Aptamers as Functional Nucleic Acids: in vitro Selection and Biotechnological Applications
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You, Kyung-Man
(Division of Molecular and Life Sciences, Pohang University of Science and Technology)
Lee, Sang-Hyun (Division of Molecular and Life Sciences, Department of Chemical Engineering, Pohang University of Science and Technology) Aesul Im (Division of Molecular and Life Sciences, Department of Chemical Engineering, Pohang University of Science and Technology) Lee, Sun-Bok (Division of Molecular and Life Sciences, Department of Chemical Engineering, Pohang University of Science and Technology) |
| 1 |
The use of mRNA display to select high-affinity proteinbinding peptides
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DOI ScienceOn |
| 2 |
2'- Fluoropyrimidine RNA-based aptamers to the 165-amino acid form of vascular endothelial growth factor (VEGF165). Inhibition of receptor binding and VEGF-induced ascular permeability through interactions requiring the exon 7-encoded domain
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DOI ScienceOn |
| 3 |
Aptasensors-The fure of biosensing
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DOI ScienceOn |
| 4 |
Peptide conjugation to an in vitro-selected DNA ligand improves enzyme inhibition
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DOI ScienceOn |
| 5 |
In vitro selection of RNA lectins: using combinatorial chemistry to interpret ribozyme evolution
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DOI ScienceOn |
| 6 |
Anti-Rex aptamers as mimics of the Rex-binding element
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| 7 |
Cutting edge: novel RNA ligands able to bind CD4 antigen and inhibit <TEX>$CD4^+$</TEX> T lymphocyte function
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| 8 |
An RNA pocket for an aliphatic hydrophobe
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DOI ScienceOn |
| 9 |
tRNA prefers to kiss
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DOI ScienceOn |
| 10 |
Molecular beacon aptamer fluoresces in the presence of Tat protein of HIV-1
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DOI ScienceOn |
| 11 |
Aptamers as ligands in affinity probe capillary electrophoresis
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DOI ScienceOn |
| 12 |
Open-tubular capillary electrochromatography of bovine beta-lactoglobulin variants A and B using an aptamer stationary phase
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DOI ScienceOn |
| 13 |
Characterization and divalent metal-ion dependence of in vitro selected deoxyribozymes which cleave DNA/RNA chimeric oligonucleotides
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DOI ScienceOn |
| 14 |
StreptoTag: a novel method for the isolation of RNA-binding proteins
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DOI ScienceOn |
| 15 |
In vitro selection of RNA aptamers specific for cyanocobalamin
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DOI ScienceOn |
| 16 |
Allosteric regulation of a ribozyme activity through ligand-induced conformational change
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| 17 |
Aptamers as analytical reagents
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| 18 |
Structure analysis of nucleic acid aptamers
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DOI ScienceOn |
| 19 |
Mutagenic PCR
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DOI |
| 20 |
In vitro selection of the RNA aptamer against the Sialyl Lewis X and its inhibition of the cell adhesion
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DOI ScienceOn |
| 21 |
Synthesis and radioiodination of a stannyl oligodeoxyribonucleotide
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DOI ScienceOn |
| 22 |
Diagnostic potential of PhotoSELEX-evolved ssDNA aptamers
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DOI ScienceOn |
| 23 |
Adapting selected nucleic acid ligands(aptamers) to biosensors
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DOI ScienceOn |
| 24 |
Automated RNA selection
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| 25 |
in vitro evolution of new ribozymes with polynucleotide kinase activity
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DOI ScienceOn |
| 26 |
Novel approach to specific growth factor inhibition in vivo: antagonism of platelet-derived growth factor in glomerulonephritis by aptamers
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DOI ScienceOn |
| 27 |
Inhibition of vascular endothelial growth factor induced angiogenesis suppresses tumour growth in vivo
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DOI ScienceOn |
| 28 |
novel nucleotide-based thrombin inhibitor inhibits clot-bound thrombin and reduces arterial platelet thrombus formation
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| 29 |
Retention and separation of adenosine and analogues by affinity chromatography with an aptamer stationary phase
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DOI ScienceOn |
| 30 |
Aptamers
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| 31 |
The generation and characterization of antagonist RNA aptamers to human oncostatin
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| 32 |
Separation of nontarget compounds by DNA aptamers
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DOI ScienceOn |
| 33 |
In vitro selection of dopamine RNA ligands
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DOI ScienceOn |
| 34 |
Aptamers: An emerging class of molecules that rival antibodies in diagnostics
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| 35 |
In vitro selection of RNA molecules that inhibit the activity of ricin A-chain
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DOI ScienceOn |
| 36 |
Pharmacokinetics and safety of an anti-vascular endothelial growth factor aptamer(NX1838) following injection into the vitreous humor of rhesus monkeys
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| 37 |
Chemical modification of hammerhead ribozymes: Catalytic activity and nuclease resistance
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DOI ScienceOn |
| 38 |
Developing aptamers into therapeutics
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| 39 |
High density, covalent attachment of DNA to silicon wafers for analysis by MALDI-TOF mass spectrometry
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DOI ScienceOn |
| 40 |
SELEX selection of high-affinity oligonucleotides for bacteriophage Ff gene 5 protein
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DOI ScienceOn |
| 41 |
In vitro selection identifies key determinants for loop-loop interactions: RNA aptamers selective for the TAR RNA element of HIV-1
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DOI ScienceOn |
| 42 |
Nucleic acid and polypeptide aptamers: A powerful approach to ligand discovery
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DOI ScienceOn |
| 43 |
Use of a high affinity DNA ligand in flow cytometry
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DOI ScienceOn |
| 44 |
Adapting selected nucleic acid ligands(aptamers) to biosensors
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DOI ScienceOn |
| 45 |
RNA aptamers that bind L-arginine with sub-micromolar dissociation constants and high enantioselectivity
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DOI ScienceOn |
| 46 |
Selection in vitro of single-stranded DNA molecules that fold into specific ligand-binding structures
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DOI ScienceOn |
| 47 |
Selection of single-stranded DNA molecules that bind and inhibit human thrombin
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DOI ScienceOn |
| 48 |
A DNA aptamer that binds adenosine and ATP
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DOI ScienceOn |
| 49 |
Detection and plasma pharmacokinetics of an anti-vascular endothelial growth factor oligonucleotide-aptamer (NX1838) in rhesus monkeys
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DOI |
| 50 |
Rapid evolution of a protein in vitro by DNA shuffling
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DOI ScienceOn |
| 51 |
Blocking the initiation of coagulation by RNA aptamers to factor VIIa
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| 52 |
RNA aptamers to S-adenosylhomocysteine: kinetic properties, divalent cation dependency, and comparison with anti-S-adenosylhomocysteine antibody
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DOI ScienceOn |
| 53 |
Controlling gene expression in living cells through small molecule-RNA interactions
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DOI |
| 54 |
High-affinity oligonucleotide ligands to human IgE inhibit binding to Fce receptor I
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| 55 |
RNA aptamers that specifically bind to the Ras-binding domain of Raf-1
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DOI ScienceOn |
| 56 |
Identification of two novel arginine binding DNAs
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| 57 |
High-resolution molecular discrimination by RNA
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| 58 |
Simple method for 30-labeling of RNA
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DOI ScienceOn |
| 59 |
Cleavage of highly structured viral RNA molecules by combinatorial libraries of hairpin ribozymes. The most effective ribozymes are not predicted by substrate selection rules
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DOI ScienceOn |
| 60 |
Nucleic acid evolution and minimization by nonhomologous random recombination
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DOI ScienceOn |
| 61 |
Isolation and characterization of 2'-fluoro-, 2'-amino-, and 2'-fluoro-/amino-modified RNA ligands to human IFN-gamma that inhibit receptor binding
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| 62 |
A semiconserved residue inhibits complex formation by stabilizing interactions in the free state of a theophylline-binding RNA
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DOI ScienceOn |
| 63 |
The application of a modified nucleotide in aptamer selection: novel thrombin aptamers containing 5-(1-pentynyl)-2'-deoxyuridine
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DOI ScienceOn |
| 64 |
Staining of cell surface human CD4 with 2'-F-pyrimidine containing RNA aptamers for flow cytometry
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DOI ScienceOn |
| 65 |
Functional requirements for specific ligand recognition by a biotinbinding RNA pseudoknot
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DOI ScienceOn |
| 66 |
In vitro selection of RNA aptamers that bind special elongation factor SelB, a protein with multiple RNA-binding sites, reveals one major interaction domain at the carboxyl terminus
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DOI |
| 67 |
An enzyme-linked oligonucleotide assay
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DOI ScienceOn |
| 68 |
In vitro selection of RNAs that bind to the human immunodeficiency virus type-1 gag polyprotein
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DOI ScienceOn |
| 69 |
Selection in vitro of an RNA enzyme that specifically cleaves single-stranded DNA
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DOI ScienceOn |
| 70 |
RNA aptamers specifically interact with the prion protein
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| 71 |
High-affinity RNA as a recognition element in a biosensor
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DOI ScienceOn |
| 72 |
2.8 A crystal structure of the malachite green aptamer
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DOI ScienceOn |
| 73 |
In vitro selection of novel RNA ligands that bind human cytomegalovirus and block viral infection
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DOI ScienceOn |
| 74 |
Proteomics: translating genomics into products
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DOI ScienceOn |
| 75 |
HIV-1 reverse transcriptase-pseudoknot RNA aptamer interaction has a binding affinity in the low picomolar range coupled with high specificity
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DOI ScienceOn |
| 76 |
An RNA motif that binds ATP
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DOI ScienceOn |
| 77 |
Liposome-anchored vascular endothelial growth factor aptamers
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DOI ScienceOn |
| 78 |
Saccharide-RNA recognition in a complex formed between neomycin B and an RNA aptamer
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DOI ScienceOn |
| 79 |
Design of highly specific cytotoxins by using transsplicing ribozymes
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DOI ScienceOn |
| 80 |
Oligonucleotide inhibitors of human thrombin that bind distinct epitopes
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DOI ScienceOn |
| 81 |
In vitro selection of RNA molecules that bind specific ligands
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DOI ScienceOn |
| 82 |
Aptamer affinity chromatography: combinatorial chemistry applied to protein purification
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DOI ScienceOn |
| 83 |
A fiber-optic microarray biosensor using aptamers as receptors
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DOI ScienceOn |
| 84 |
Enhancing RNA repair efficiency by combining trans-splicing ribozymes that recognize different accesible sites on a target RNA
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DOI ScienceOn |
| 85 |
RNA aptamers that bind L-arginine with sub-micromolar dissociation constants and high enantioselectivity
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DOI ScienceOn |
| 86 |
Nonradioactive 3'-end labeling of RNA molecules of different lengths by terminal deoxynucleotidyl transferase
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DOI |
| 87 |
Stereospecific recognition of tryptophan agarose by in vitro selected RNA
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| 88 |
RNA molecules that bind to and inhibit the active site of a tyrosine phosphatase
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DOI ScienceOn |
| 89 |
In vitro selection of aptamers that act with <TEX>$Zn^{2+}$</TEX>
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| 90 |
DNA aptamers block L-selectin function in vivo. Inhibition of human lymphocyte trafficking in SCID mice
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DOI ScienceOn |
| 91 |
Solution structure of the tobramycin-RNA aptamer complex
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DOI ScienceOn |
| 92 |
An enzyme-linked oligonucleotide assay
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DOI ScienceOn |
| 93 |
Potent 2'-amino-2'-deoxypyrimidine RNA inhibitors of basic fibroblast growth factor
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DOI ScienceOn |
| 94 |
Oligomeric and biogenetic combinatorial libraries
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DOI ScienceOn |
| 95 |
Staining of cell surface human CD4 with 2'-F-pyrimidine-containing RNA aptamers for flow cytometry
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DOI ScienceOn |
| 96 |
The RNA aptamer-binding site of hepatitis C virus NS3 protease
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DOI ScienceOn |
| 97 |
Aptamers as therapeutic and diagnostic reagents: problems and prospects
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DOI ScienceOn |
| 98 |
SELEX primer
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DOI |
| 99 |
Systematic evolution of ligands by exponential enrichment: RNA ligands to bacteriophage T4 DNA polymerase
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DOI |
| 100 |
Anti-L-selectin oligonucleotide ligands recognize CD62L-positive leukocytes: binding affinity and specificity of univalent and bivalent ligands
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DOI ScienceOn |
| 101 |
A tetracycline-binding RNA aptamer
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DOI ScienceOn |
| 102 |
In vitro selection of a 7-methyl-guanosine binding RNA that inhibits translation of capped mRNA molecules
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DOI ScienceOn |
| 103 |
The structural basis for molecular recognition by the vitamin <TEX>$B^ {12}$</TEX> RNA aptamer
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DOI ScienceOn |
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