• Title/Summary/Keyword: meaning of work

Search Result 898, Processing Time 0.031 seconds

Reactive oxygen species-dependent down-regulation of ubiquitin C-terminal hydrolase in Schizosaccharomyces pombe (Schizosaccharomyces pombe에서의 유비퀴틴 C-말단 가수분해효소의 활성산소종 의존성 하향조절)

  • Jo, Hannah;Lim, Hye-Won;Kwon, Hee-Souk;Lim, Chang-Jin;Park, Kwang Hark;Jin, Chang Duck;Kim, Kyunghoon
    • Korean Journal of Microbiology
    • /
    • v.52 no.2
    • /
    • pp.236-241
    • /
    • 2016
  • The Schizosaccharomyces pombe $sdu1^+$ gene, belonging to the PPPDE superfamily of deubiquitinating enzyme (DUB) genes, was previously shown to encode a protein with ubiquitin C-terminal hydrolase (UCH) activity and to participate in the response against oxidative and nitrosative stresses. This work focused on the reactive oxygen species (ROS)-dependent regulation of the S. pombe $sdu1^+$ gene. UCH activities, encoded by the $sdu1^+$ gene, were attenuated in the S. pombe cells exposed to $H_2O_2$, superoxide radical-generating menadione (MD), and nitric oxide (NO)-generating sodium nitroprusside (SNP). Reduced glutathione (GSH) and its precursor N-acetylcysteine (NAC) were able to significantly enhance the UCH activities in the absence or presence of $H_2O_2$. However, the influences of both GSH and NAC on the ROS levels in the absence or presence of $H_2O_2$ were opposite to their effects on the UCH activities under the same conditions. The UCH activities in the Sdu1-overexpressing S. pombe cells were also diminished under exposure to $H_2O_2$, MD and SNP, but still remained to be higher than those in the vector control cells. In brief, it is proposed that the S. pombe $sdu1^+$ gene is regulated by ROS in a negative manner, the meaning of which largely remains elusive.

Searching for Laws and Systems to Revitalize Private Archives (민간 아카이브 활성화를 위한 법·제도 모색)

  • Sohn, Dong You
    • The Korean Journal of Archival Studies
    • /
    • no.69
    • /
    • pp.7-33
    • /
    • 2021
  • From the beginning of the enactment and implementation of the Public Records Management Act, there has been a steady discussion on the establishment of local archives. Local archives include not only administrative records of local governments, but also private archives such as containing the lives of residents. Along with the academic discussion, there have been movements for local autonomy and decentralization. Currently, interest and discussion on private archiving are in the historical flow. In addition, private archiving has become a social concern because of the establishment of systems such as the Public Records Management Act and the Information Disclosure Act, the establishment of a digital environment, and the spread of the meaning and value of village community activities. There are several government agencies related to private archiving, and the grounds for performing their work are different, and there are many central administrative agencies to which they belong. Therefore, I propose that the National Archives take the lead and form a 'Consortium of Private archives Management Institutions'. The organization should promote first, cooperation of collection information and archives, second, coordination of tasks and functions between institutions, and third, establishment of a nationwide private archives management system. Now is our chance. Instead of reacting on an ad hoc basis, respond systematically with a long-term perspective.

A Study on the Art Works Creation of the Subconscious Experiences though the Scene Setting Technique : Focused on the Floral Art Work Creation based on Artist's Experiences (장면화 기법을 통한 무의식적 경험의 작품화에 관한 연구 -본인 경험을 바탕으로 한 화예 작품 창작을 중심으로-)

  • Kim, Dawoon;Yoo, Taeksang
    • Journal of the Korean Society of Floral Art and Design
    • /
    • no.44
    • /
    • pp.53-73
    • /
    • 2021
  • This study is on the creation of art works through the methodological process of deducting the experiences and inspired feeling which the researcher experienced in the subconscious level as well as the conscious level in the field of floral art creation. The scene setting technique was applied to seize inner experiences and feeling in subconscious level. More concretely, visual note technique and image research technique were applied to record and preserve scenes as the seized inner mental images. To delineate the contents, the researcher created art works based on the experiences during the preparation period at the small town of Tours in France as well as the competitive and tough every day life during the attendance at the fashion school of ESOMD International Paris. The researcher was able to create 5 art works of Deja Vu, 'ㅅ(Seoul-Paris)', '崩(A Mountain on Two Moons)', '燈 (Load out and Stay)', 'ㅇ'deducting the deep experiences and inspired feeling through the methodological process in the subconscious level as well as the conscious level. The researcher was able to explore inner experiences finding self in disquietude and process of personal realization through the creation. The meaning of this research could be found as a case of qualitative research which presents approaches utilizing method of deducting experiences in subconscious level and applying to the creation of art works.

A Study on the Directorial Approaches of by Juan Mayorga (후안 마요르가 작 <하멜린> 연출적 접근방법 연구)

  • Lee, Seo-A;Cho, Joon-Hui
    • Journal of Korea Entertainment Industry Association
    • /
    • v.15 no.8
    • /
    • pp.161-180
    • /
    • 2021
  • The purpose of this study is to define Juan Mayorga's play Hamelin as a Post-Epic Theatre and to study the practical directing technique for Hamelin as a Post-Epic Theatre. Post-Epic Theatre, which appeared after the Post-drama, has the purpose of presenting social issues, communicating interactively between the actors and the audience, and making the audience think about the issues presented by the techniques of immersion and alienation. To this end, after examining the theoretical background of the Post-Epic Theatre, the characteristics of the Post-Epic Theatre of Hamelin were identified and based on these features, '1. Building a visual image based on a Cubistic multifocal concept' and '2. The concept of directing was derived from reinforcing Meta-drama through role-playing'. Next, the actual directing technique was discussed, focusing on the chain action of immersion and alienation that occurs in the form of communication between actors and audiences. '1. Presenting the characteristics of the work through Post-Epic Theatre scenography', '2. Co-existence of actors and characters', '3. Building and utilizing body-centered gestus' are them. As a result, demanding an active attitude from the audience, various experiences such as critical thinking of the audience, strengthening the characteristics of post-epic dramas, and active meaning creation were made possible.

Violence Experiences of Community Mental Health Nurse (지역사회 정신보건간호사의 폭력경험)

  • Kim, Mi-Hye;Kim, Han-Na;Shin, Yoon-Mee;Oh, Hyun-Mi;Lee, Jeong-Seop
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.16 no.12
    • /
    • pp.8626-8636
    • /
    • 2015
  • This study is a qualitative study to disclose the meaning and reality of violence experiences of the mental health nurses by the phenomenological approach. This study is done with the participation of 9 community mental health nurses who have work experiences more than 3 years in the city of S, from Nov 7, 2014 till Dec 21, 2014. The result of the study revealed that the violence experiences of this study participants may be categorized into 4 categories, 'a small boat running into a storm', 'open sea', 'a small boat lost of the sign post', 'a captain controlling the rudder' and may be identified with 11 theme cluster and 32 theme.Therefore violence from patients who have experienced mental health nurse could be found to affect even the identity of the mental health nurse as well as threaten safety of professionals. This may threaten the quality of service provided to the patient, so we have to accept reality as a serious problem. Also it has been preceded by what the support program development of the nursing organization for the nurse who is violence victims with preparing for violence Prevention. As the result we suggest that you prepare a practical measures for the safety and quality nursing services performed by mental health nurses.

Investigation of the Korean Traditional Hobun(Oyster shell W.) Manufacturing Technique : Centering on Calcination Method (전통 호분(합분) 제조기술 연구 : 소성방법을 중심으로)

  • Lee, Han-Hyoung;Kim, Soon-Kwan;Kim, Ho-Jeong;Jeong, Hye-Young
    • Journal of Conservation Science
    • /
    • v.23
    • /
    • pp.103-118
    • /
    • 2008
  • Hobun(Oyster shell W.) is a traditional material used as extender and white pigment from ancient times. The production method of it, however, has been discontinued. We have studied the traditional production method of Hobun through calcination of oyster shell, which is one of the traditional ways for preparing Hobun. Our work has the important meaning in that we can reproduce the manufacturing method of the discontinued traditional material and also it provides a solid background knowledge to stabilize the production and supply of Hobun for the cultural asset repairing materials. The result can be summarized as followings: The production processes of Hobun by calcination method are divided into 4 steps - calcination ${\rightarrow}$ slaking(pulverization) ${\rightarrow}$ separating fine powder by submergence in water ${\rightarrow}$ drying. In calcination step, the temperature is required to exceed $700^{\circ}$ to get pure white color of Hobun, since organic materials in the shell cause the final powder to be less white below $600^{\circ}$. And the calcination methods produce significant amount of calcium hydroxide, which is incongruent for pigment materials without additional treatments. The experimental study also demonstrated that the additional treatment process introduced in traditional paintings can be a probable process since the calcium of potassium hydroxide is observed to be promoted by this treatment. It is also concluded that, the calcination method of Hobun is appropriate for a small amount and high quality production.

  • PDF

The First Telescope in the Korean History I. Translation of Jeong's Report (한국사 최초의 망원경 I. 정두원(鄭斗源)의 "서양국기별장계(西洋國奇別狀啓)")

  • Ahn, Sang-Hyeon
    • Journal of Astronomy and Space Sciences
    • /
    • v.26 no.2
    • /
    • pp.237-266
    • /
    • 2009
  • In 1631 A.D. Jeong Duwon, an ambassador of the Joseon dynasty was sent to the Ming dynasty. There he met $Jo\tilde{a}o$ Rodrigues, a Jesuit missionary, in Dengzhou of Shandong peninsula. The missionary gave the ambassador a number of results of latest European innovations. A detailed description on this event was written in 'Jeong's official report regarding a message from an European country'(西洋國奇別狀啓), which is an important literature work to understand the event. Since the document was written in classical Chinese, we make a comprehensive translation to Korean with detailed notes. According to the report, the items that Rodrigues presented include four books written in Chinese that describe European discoveries about the world, a report on the tribute of new cannons manufactured by Portuguese in Macao, a telescope, a flintlock, a Foliot-type mechanical clock, a world atlas drawn by Matteo Ricci, an astronomical planisphere, and a sun-dial. We discuss the meaning of each item in the Korean history of science and technology. In particular, Jeong's introduction is an important event in the history of Korean astronomy, because the telescope he brought was the first one to be introduced in Korean history. Even though king Injo and his associates of the Joseon dynasty were well aware of the value as military armaments of new technologies such as telescopes, cannons, and flintlocks, they were not able to quickly adopt such technologies to defend against the military threat of Jurchen. We revisit the reason in view of the general history of science and technology of east-Asian countries in the 17th century.

Stephen Sondheim's Experiments and Strategies for Musical Fusion Style (스티븐 손드하임의 뮤지컬 융합 양식을 향한 실험과 전략)

  • Lee, Eun-Hye
    • Journal of Korea Entertainment Industry Association
    • /
    • v.13 no.7
    • /
    • pp.15-23
    • /
    • 2019
  • This paper aims to identify the characteristics implied in the process of change of Stephen Sondheim's musical style and to derive the structural communication tools that connect the creator and audience and the implications. The strategies that appear in Sondheim's musical works are the following. First, Sondheim's early musical works follow the principles of book musical and emphasize the integration faithful to the basic elements such as the rhythm and meaning of the lyrics. Second, in the era of early postmodernism, Sondheim attempts the principle of extreme deconstruction through the concept musical Company and pursues rational thought through fragmented dramatic flow. Third, while maintaining dramatic linearity to overcome the lack of immersion caused by extreme deconstruction, Sondheim realizes a more elaborate and formalized fusion style of the principles of integration and deconstruction through the choruses and the songs of the characters in Little Night Music and Sweeney Todd. Finally, Sondheim attempts multiple experiments to break down the boundaries of act and scene and to express new subject matters through his works such as Sunday Park with George and Into the Woods. In conclusion, Sondheim's fusion experiments and strategies are the process of finding a framework and a medium of communication to induce dramatic immersion of audience and at the same time create rational thinking about social problems to deliver the message of the creative work with the leading aesthetics of the modern musical's box-office success.

The Development of the Conceptual Model Visualization Program (개념모델 가시화 프로그램의 개발)

  • Choi, Hong-Seok;Okazaki, Akira
    • Science of Emotion and Sensibility
    • /
    • v.13 no.3
    • /
    • pp.573-580
    • /
    • 2010
  • The earlier KANSEI evaluation had to choose not to overlap the opposite meaning of the words, had to choose that some figures are shown step by step and had to choose be prepared things in advance. However, The Study shows a method which visualizes the imprecise evaluations of human without choosing evaluation items which are not prepared figures. The program is used the way which is entered by hand-drawing that the subjects use the way to enter their subjective feelings about the evaluations presented by using the mouse or the graphics tablet. It is possible to express imprecise things about evaluations and the method of drawing is free. The program provides that we can express our thinking by drawing and there are a few limits and the prescribed standard. The area ratio of each circle is expressed as a pie chart and the area of circle what is drawn which is counted automatically at the same time. These things are possible not only to modify a transparency, a thickness of a line, a color and the area of circle what is drawn, but also to adjust the area of circle. The conceptual model is visualized that expresses something by hand-drawing such as a circle. The conceptual model has wide range of applications such as a personnel evaluation, a suffering evaluation and product evaluation. The program currently has been testing the effective of the program's possibilities which is used with the personnel appraisal tool of the nurses themselves who work in nurse support department where the St. Marianna University School of Medicine Hospital is. And also the program is proceeding with development to visualize the conceptual model by dynamic interfaces effectively and the program is applied such as KJ method and a program is used to express the kind of the patient's pain and its level.

  • PDF

The study on the Integrated Thinking Ability in Problem Based Learning Program Using Historical Materials in Mathematics (수학 문제중심학습(PBL)에서 융합적 사고력 신장 도모에 관한 의의 - 역사 소재를 중심으로-)

  • Hwang, Hye Jeang;Huh, Nan
    • Communications of Mathematical Education
    • /
    • v.30 no.2
    • /
    • pp.161-178
    • /
    • 2016
  • Mathematics problem based learning(PBL), which has recently attracted much attention, is a teaching and learning method to increase mathematical ability and help learning mathematical concepts and principles through problem solving using students' mathematical prerequisite knowledge. In spite of such a quite attention, it is not easy to apply and practice PBL actually in school mathematics. Furthermore, the recent instructional situations or environments has focused on student's self construction of their learning and its process. Because of this reason, to whom is related to mathematics education including math teachers, investigation and recognition on the degree of students' acquisition of mathematical thinking skills and strategies(for example, inductive and deductive thinking, critical thinking, creative thinking) is an very important work. Thus, developing mathematical thinking skills is one of the most important goals of school mathematics. In particular, recently, connection or integration of one subject and the other subject in school is emphasized, and then mathematics might be one of the most important subjects to have a significant role to connect or integrate with other subjects. While considering the reason is that the ultimate goal of mathematics education is to pursue an enhancement of mathematical thinking ability through the enhancement of problem solving ability, this study aimed to implement basically what is the meaning of the integrated thinking ability in problem based learning theory in Mathematics. In addition, using historical materials, this study was to develop mathematical materials and a sample of a concrete instructional guideline for enhancing integrated thinking ability in problem based learning program.