There is a trend toward the world's manufacturing sites moving to East Asia. After manufacture, these products are transported to the advanced nations for their consumption demands. Among such advanced nations, the U.S.A. has the largest demand, and then Japan and European countries follow. It should be noted that the infrastructures of the Asian districts used for the production sites are rather limited, and the volume of products transported from these districts of Asia to the U.S.A is becoming tremendously large. This situation is causing very serious traffic problems. New products are required to be transported swiftly by air. Once the consumption and market demands are stable however, the products should be sent rather slowly, but in larger amounts. However, the airports of China are quite restricted in capacity, while the transportation volume is becoming large. As a result, transportation cost and the time required for transportation are increasing. Now, a third method is appearing. This is the so-called Sea and Air transportation. The cost and time in transit of this mode take mean positions between Air and Ocean services. At present there exists no well-thought-out strategy for how to allocate these three methods of transportation. This paper is an attempt to theoretically describe this mechanism and to discover the optimal way to allocate the three modes. For this purpose, several mathematical properties of value and cost of the products are defined, and on this basis a simulation of the transportation is established.
Iswanto, Apri Heri;Febrianto, Fauzi;Hadi, Yusuf Sudo;Ruhendi, Surdiding;Hermawan, Dede;Fatriasari, Widya
Journal of the Korean Wood Science and Technology
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v.46
no.2
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pp.155-165
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2018
The objective of the research was to evaluate the effect of particle pre-treatment on physical, mechanical, and durability of jatropha fruit hulls (JFH) particleboard. The pre-treatments included were immersing in cold water, hot water, and acetic acid solution. After each treatment, the particles were dried up to 3% moisture content. Urea-formaldehyde (UF) resin was used to fabricate particleboards with board size, thickness and density target of 25 cm by 25 cm, 0.80 cm, and $0.70g/cm^3$, respectively. Board pressed at $130^{\circ}C$ for 10 minutes, and $25kg/cm^2$ pressure. The evaluation of particleboard followed the JIS A 5908-2003. Whilist their resistance to subterranean termite test (mass loss, mortality, antifeedant value and feeding rate) refers to the Indonesian standard (SNI 01.7207-2006). The physical and mechanical properties of particleboards showed that all pre-treatments decreased the pH of particles. Overall, all particle immersing treatments resulted of better physical and mechanical properties of particleboard than those of untreated ones. The acetic acid treatment resulted the best physical and mechanical properties of particleboard. Based on the mass loss of JFH particleboard, hot water and acetic acid treated particleboards were classified into weak resistance to subterranean attack. The other two treatments were classified into very weak resistance. Hot water treated particleboard provided the highest mortality and antifeedant as much as 87.40% and 34.20%, respectively. Based on antifeedant classification, hot water treated particleboards were classified into moderately strong resistance, while other treatments were categorized into weak resistance. The lowest feeding rate value ($45.30{\mu}g/termite/day$) was attained by hot water treatment.
Purpose - In the development of new products, suppliers involvement and developing products jointly can be said to be strategic activities that utilize the lack of knowledge from external organizations. In this new product development, supplier involvement has been proven to have a positive impact on new product development performance for a long time by previous research. However, sufficient academic research has not been conducted on the influence of supplier involvement in various product strategies or sales strategies that buyers make in order to secure a competitive advantage in the market. This study argues that product strategy and sales strategy used by buyers in the development of new products will control the effect of supplier involvement on new product development performance in order to compensate the lack of these academic aspects. Research design, data, and methodology - Specifically, we selected the modularization strategy of the product as the product strategy, which is considered as an important strategy in the new product development through the preceding research, and the mass customer satisfaction strategy was chosen as the sales strategy. In order to achieve these research objectives, regression analysis was conducted using data from manufacturing productivity panel collected jointly by the Ministry of Industry, Trade and Industry and the Korea Productivity Center. Results - As a result, supplier involvement and new product development performances (development cost efficiency, customer satisfaction) were positively related. The product modularity strategy proved to have an interactive effect on the relationship between supplier involvement and new product development performances (development cost efficiency, customer satisfaction). However, it has not been confirmed that there is a statistically significant interaction effect between supplier involvement and new product development performances. Conclusions - Supplier involvement has positive relationships with NPD performance. In addition, product modularity strategies have interaction effects with supplier involvement and affect new product development performance (development cost efficiency and customer satisfaction). The results of this study are of academic significance in the case of lack of empirical studies on the effect of supplier participation on the effect of buyer 's strategy when a supplier participates and develops new products jointly.
The technique for in situ simultaneous measurements of IR-RAS and QCM, which has been developed for investigation of corrosion in gaseous environments, was employed to study the effects of an extremely thin water layer on the corrosion rate. An evaporated copper film on a QCM element was exposed to air containing water vapor and $SO_2$, and time-resolved IR-RAS spectra were measured and mass gains were simultaneously followed with QCM. The tested ranges of relative humidity (RH) and concentration of $SO_2$ were 60% - 90% and 1 - 20 ppm, respectively. On the basis of 2D-IR analysis, the corrosion products were determined to be Chevreul's salt ($CuSO_3Cu_2SO_3{\cdot}2H_2O$) and $CuSO_4{\cdot}5H_2O$. By constructing curves of the relations between band intensities of IR spectra and mass gains of QCM for the corrosion products, the time variations in each product were determined from spectral experiments on copper plates. The thicknesses of physically adsorbed water layers in course of the corrosion process were also determined from water band intensities. The results showed that the thickness of the physically adsorbed water layer increased with increase in RH, and it also increased with increase in accumulation of corrosion products. The latter is probably due to the capillary effect of the corrosion products.
Hem, Lina;Khay, Sathya;Choi, Jeong-Heui;Morgan, E.D.;El-Aty, A.M. Abd;Shim, Jae-Han
Toxicological Research
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v.26
no.2
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pp.149-155
/
2010
The pesticide trichlorfon is readily degraded under experimental conditions to dichlorvos. A method has therefore been developed by which residues of trichlorfon in milk are determined as dichlorvos, using gas chromatography with ${\mu}$-electron capture detection. The identification of dichlorvos was confirmed by mass spectrometry. Milk was extracted with acetonitrile followed by centrifugation, freezing lipid filtration, and partitioning into dichloromethane. The residue after partitioning of dichloromethane was dissolved in ethyl acetate for gas chromatography. Recovery concentration was determined at 0.5, 1.0, and 2.0 of times the maximum permitted residue limits (MRLs) for trichlorfon in milk. The average recoveries (n = 6) ranged from 92.4 to 103.6%. The repeatability of the measurements was expressed as relative standard deviations (RSDs) ranging from 3.6%, to 6.7%. Limit of detection (LOD) and limit of quantification (LOQ) were 3.7 and $11.1{\mu}g/l$, respectively. The accuracy and precision (expressed as RSD) were estimated at concentrations from 25 to $250{\mu}g/l$. The intra- and inter-day accuracy (n = 6) ranged from 89.2% to 91% and 91.3% to 96.3%, respectively. The intra- and inter-day precisions were lower than 8%. The developed method was applied to determine trichlorfon in real samples collected from the seven major cities in the Republic of Korea. No residual trichlorfon was detected in any samples.
The study aimed to investigate a novel approach by utilizing liquid chromatography (LC) and liquid chromatography-mass spectrometry (LC-MS) to separate, identify and characterize very nominal quantities of degradation products (DPs) of balsalazide along with its process related impurities without isolation from their reaction mixtures. The impurities along with balsalazide were resolved on spherisorb ODS2 (250×4.6 mm, 5.0 ㎛) column at room temperature using 0.2 M sodium acetate solution at pH 4.5 and methanol in the ratio of 55:45 (v/v) as mobile phase pumped isocratically at 1.0 mL/min as mobile phase and UV detection at 255 nm. The method shows sensitive detection limit of 0.003 ㎍/mL, 0.015 ㎍/mL and 0.009 ㎍/mL respectively for impurity 1, 2 and 3 with calibration curve liner in the range of 50-300 ㎍/mL for balsalazide and 0.05-0.30 for its impurities. The balsalazide pure compound was subjected to stress studies and a total of four degradation products (DPs) were formed during the stress study and all the DPs were characterized with the help of their fragmentation pattern and the masses obtained upon LC-MS/MS. The DPs were identified as 3-({4-[(E)-(4-hydroxyphenyl) diazenyl]benzoyl}amino)propanoic acid (DP 1), 4-[(E)-(4-hydroxyphenyl)diazenyl] benzamide (DP 2), 5-[(E)-(4-carbamoylphenyl)diazenyl]-2-hydroxybenzoic acid (DP 3) and 3-({4-[(E)-phenyldiazenyl]benzoyl}amino)propanoic acid (DP 4). Based on findings, it was concluded that, the proposed method was successfully applicable for routine analysis of balsalazide and its process related impurities in pure drug and formulations and also applicable for identification of known and unknown impurities of balsalazide.
Since the existing mass production and consumption systems are no longer sustainable, countries are pushing for policies to make fisheries by-products as resources in an eco-friendly manner, and international standards are also being strengthened to increase the value of by-products. In Korea, economic and environmental perceptions of the by-products are rapidly changing, such as realizing carbon neutrality and enhancing circular resources by Korean Sustainable Development Goals. Raw materials derived from the by-products have been steadily imported from 2018. In particular, the number of imports of fish collagen peptides was only 16 number of times in 2017, but was rapidly increased to 483 number of times in 2020. Simultaneously, the demand for raw materials and nutrients for health functional food derived from fish by-products, which did not exist statistically until 2017, started to arise from 2018, and in 2019, consumption of high-value-added raw materials for fish by-products increased by 45% compared to the previous year. However, limitations are in legal and biotechnical industry aspects while its value as a biomaterial is recognized in the by-products-related industry. In this study, therefore, the status of by-products for upcycling biomaterials was reported and provided a scientific basis for supporting governmental strategies. In order to fulfill with the principles of a sustainable circular economy, the factors on hinder the marine bio-industrialization of the by-products were derived and suggested directions and plans for development into a high-value added the by-products as the marine bio-industry by substituting imported raw materials to support the development.
The purpose of this study was to examine the consumption behaviors regarding environment-friendly agricultural products by food-related lifestyles of housewives. The data were collected from 298 housewives living in Yeungnam region through a self-administered questionnaire during April, 2010. Frequencies, Cronbach's $\alpha$, factor analysis, cluster analysis, one-way analysis of variance, Duncan's multiple range test and chi-square test were conducted by SPSS Windows. The results obtained from this study were as follows. Lifestyles were categorized into five factors by factor analysis: healthy-seeking type, popularity-seeking type, convenience-seeking type, safety-seeking type and taste-seeking type. The respondents belonged to one of three groups by cluster analysis: popularity-seeking group, convenience-seeking group, and wellbeing-seeking group. The main reason given for purchasing environment-friendly agricultural products was safety. The respondents were satisfied with the safety of environment-friendly agricultural products the most. Many respondents purchased environment-friendly agricultural products at large discount markets, and received information about them from mass media. There were significant differences among three groups in the place of purchase environment-friendly agricultural products, information source for environment-friendly agricultural products, most important factor when purchasing environment-friendly agricultural products, the level of satisfaction with environment-friendly agricultural products and the purchase rate of environment-friendly agricultural products among the monthly food expenses.
Oxidation behaviours of ash free coal (AFC), carbon, and H2 fuels were investigated with a coin type molten carbonate fuel cell. Because AFC has no electrical conductivity, its oxidation occurs via gasification to H2 and CO. An interesting behaviour of mass transfer resistance reduction at higher current density was observed. Since the anode reaction has the positive reaction order of H2, CO2 and H2O, the lack of CO2 and H2O from AFC results in a significant mass transfer resistance. However, the anode products of CO2 and H2O at higher current densities raise their partial pressure and mitigate the resistance. The addition of CO2 to AFC reduced the resistance sufficiently, thus the resistance reduction at higher current densities did not appear. Electrochemical impedance results also indicate that the addition of CO2 reduces mass transfer resistance. Carbon and H2 fuels without CO2 and H2O also show similar behaviour to AFC: mass transfer resistance is diminished by raising current density and adding CO2.
Exosomes have gained the attention of the scientific community because of their role in facilitating intercellular communication, which is critical in disease monitoring and drug delivery research. Exosome research has grown significantly in recent decades, with a focus on the development of various technologies for isolating and characterizing exosomes. Among these efforts is the use of matrix-assisted laser desorption ionization (MALDI) mass spectrometry (MS), which offers high-throughput direct analysis while also being cost and time effective. MALDI is used less frequently in exosome research than electrospray ionization due to the diverse population of extracellular vesicles and the impurity of isolated products, both of which necessitate chromatographic separation prior to MS analysis. However, MALDI-MS is a more appropriate instrument for the analytical approach to patient therapy, given it allows for fast and label-free analysis. There is a huge drive to explore MALDI-MS in exosome research because the technology holds great potential, most notably in biomarker discovery. With methods such as fingerprint analysis, OMICs profiling, and statistical analysis, the search for biomarkers could be much more efficient. In this review, we highlight the potential of MALDI-MS as a tool for investigating exosomes and some of the possible strategies that can be implemented based on prior research.
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