• Herbal Formula Science
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• v.16 no.1
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• pp.169-183
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• 2008

In this study, we measured body mass index, visceral fat ratio and 6 parts of body, neck circumference, circumference of upper arm, chest circumference, abdomen circumference, hip circumference, and thigh circumference by bioimpedence analysis system, after taking Gyeongshingangjeehwan16 (GGEx16) in five months except the first period before taking GGEx16 on 49 women who are obesity or high-level obesity. In order to examine the significance test for the effect of obesity improvement of GGEx16, we practices repeated measure ANOVA with values of measurement variables in 6 monthly times. As a result of all measurement variables, there were significant difference (P-value=0.001). Therefore, we can say that GGEx16 is effective about obesity improvement. As it dramatically decreased between second measure period and first measure period for all measure variables, we can see that there were the most effect of GGEx16 in the first time after taking GGEx16. It is known that a important measurement variable to have a effect for obesity improvement about two variable which are body mass index and visceral fat ratio is waist circumference through correlation analysis. The result of whether there are differences to effect of obesity improvement for GGEx16 around the climacteric, there were significant difference for the effect of obesity improvement for GGEx16 around the climacteric about all parts of body (P-value=0.001). There were also powerfully difference in effect of obesity improvement for GGEx16 around the climacteric about all parts of body (P-value=0.001). Especially, the climacteric before is more effective than the climacteric after in the aspect of the effect of GGEx16.

• Food Science of Animal Resources
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• v.34 no.6
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• pp.749-756
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• 2014

A rapid and simple analytical method for L-carnitine was developed for infant and toddler formulas by liquid chromatography tandem mass spectrometry (LC-MS/MS). A 0.3 g of infant formula and toddler formula sample was mixed in a 50 mL conical tube with 9 mL water and 1 mL 0.1 M hydrochloric acid (HCl) to chemical extraction. Then, chloroform was used for removing a lipid fraction. After centrifuged, L-carnitine was separated and quantified using LC-MS/MS with electrospray ionization (ESI) mode. The precursor ion for L-carnitine was m/z 162, and product ions were m/z 103 (quantitative) and m/z 85 (qualitative), respectively. The results for spiked recovery test were in the range of 93.18-95.64% and the result for certified reference material (SRM 1849a) was within the range of the certificated values. This method could be implemented in many laboratories that require time and labor saving.

• Analytical Science and Technology
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• v.28 no.6
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• pp.460-466
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• 2015

An isotope dilution liquid chromatography tandem mass spectrometry was developed as a primary method for the quantitative analysis of cholesterol in infant formula. Cholesterol-d₄ was used as an internal standard and spiked into the infant formula sample. In order to release cholesterol out of cholesteryl ester, which is cholesterol bound to fatty acids in infant formula, saponification was carried out. Saponification conditions were optimized with heating temperature, reaction time and the concentration of KOH. The optimum conditions were as follows; heating temperature was 70 ℃, reaction time was 180 min and the concentration of KOH was 0.8 mL of 8 M KOH for about 0.1 g infant formula sample. Extraction of cholesterol out of sample solution was carried out with hexane uisng liquid-liquid extraction. Chromatographic analysis was carried out using Phenomenex Kinetex C₁₈ column. Mobile phase was 0.1% acetic acid in methanol/water (v/v, 99/1) and flow rate was 0.3 mL/min. Cholesterol and cholesterol-d₄ were monitored at mass transfer m/z 369/259 and 373/263 respectively. Reproducibility of the method was evaluated to be 0.23% of the measurement result. The expanded uncertainty of the measurement result of cholesterol in infant formula was approximately 1.9% at a 95% confidence level. NIST standard reference material having certified values of cholesterol in infant formula, was analyzed in order to verify this method. The ID-LC/MS/MS results were well agreed with the certified values of NIST SRM within the uncertainty.

• Bulletin of the Society of Naval Architects of Korea
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• v.23 no.3
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• pp.10-16
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• 1986

This paper deals with a simple, approximate formula to predict the natural frequencies of the sagged cable structures. Assuming that the propagation velocity of the lateral wave is dependent only on the local mass per unit length and local tension, the explicit simple formula to predict the fundamental period is newly derived. The modified form of these formula is also presented for the prediction of the fundamental period of general shaped cable structures. The results of comparison shows fairly good agreements with experimental results and with theoretical ones. This formula is also used to predict the natural frequencies of a long vertical cable and the derived approximate formula in that case, becomes identical to the exact solution.

• Korean Journal of Community Nutrition
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• v.21 no.2
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• pp.178-189
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• 2016

Objectives: The objectives of the study were to assess body composition, physical activity level (PAL), basal metabolic rate (BMR), and daily energy expenditure (DEE) and to examine associations between PAL and body composition, BMR, and DEE of elderly in Busan. Methods: A cross-sectional study was conducted among 226 elderly aged 65-93 years. Body composition was measured by Inbody 720. PAL was calculated by daily activity diary. BMR was calculated by Harris-Benedict (H-B) formula, Dietary Reference Intakes (DRI) formula, and Inbody 720 measurement. DEE was calculated by H-B formula, DRI formula, Inbody 720 measurement, and estimated energy requirements (EER) formula. Results: The mean fat free mass (FFM) in elderly men was significantly higher than that in elderly women (p<0.001). The mean percent body fat and fat mass (FM) in elderly women were significantly greater than those in elderly men (p<0.001, p<0.001). The mean PAL in elderly men (1.59) was significantly higher than that in elderly women (1.53) (p<0.001). The mean DEEs calculated by 3 methods except for H-B formula in elderly men were higher than EER for elderly men (2000kcal). The mean DEEs calculated by 4 different methods in elderly women were higher than EER for elderly women (1600kcal). Age showed significantly negative correlations with height (p<0.001, p<0.001), FFM (p<0.001, p<0.001), BMRs calculated by H-B formula (p<0.001, p<0.001), DRI formula (p<0.001, p<0.001) and Inbody 720 measurement (p<0.05 p<0.01) and DEEs calculated by H-B formula (p<0.001, p<0.001), DRI formula (p<0.001, p<0.001), Inbody 720 measurement (p<0.05, p<0.05), and EER formula (p<0.001, p<0.001) in elderly men and elderly women. PAL showed significantly positive correlations with FFM (p<0.05), BMR by Inbody 720 measurement (p<0.05) in elderly men and negative correlations with FM (p<0.05) in elderly women. Conclusions: Based on the results, PAL was associated with greater FFM in elderly men and lesser FM in elderly women. Therefore, nutritional education to increase physical activity for health promotion in late life is needed in the elderly.

• Geomechanics and Engineering
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• v.30 no.6
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• pp.503-515
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• 2022

The permeability coefficient is an essential parameter for the study of seepage flow in fractured rock mass. This paper discusses the feasibility and application value of using readily available RQD (rock quality index) data to estimate mine water inflow and grouting quantity. Firstly, the influence of different fracture frequencies on permeability in a unit area was explored by combining numerical simulation and experiment, and the relationship between fracture frequencies and pressure and flow velocity at the monitoring point in fractured rock mass was obtained. Then, the stochastic function generation program was used to establish the flow analysis model in fractured rock mass to explore the relationship between flow velocity, pressure and analyze the universal law between fracture frequency and permeability. The concepts of fracture width and connectivity are introduced to modify the permeability calculation formula and grouting formula. Finally, based on the on-site grouting water control example, the rock mass quality index is used to estimate the mine water inflow and the grouting quantity. The results show that it is feasible to estimate the fracture frequency and then calculate the permeability coefficient by RQD. The relationship between fracture frequency and RQD is in accordance with exponential function, and the relationship between structure surface frequency and permeability is also in accordance with exponential function. The calculation results are in good agreement with the field monitoring results, which verifies the rationality of the calculation method. The relationship between the rock mass RQD index and the rock mass permeability established in this paper can be used to invert the mechanical parameters of the rock mass or to judge the permeability and safety of the rock mass by using the mechanical parameters of the rock mass, which is of great significance to the prediction of mine water inflow and the safety evaluation of water inrush disaster management.

• The Bulletin of The Korean Astronomical Society
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• v.35 no.1
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• pp.80-80
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• 2010

About 50% of Active Galactic Nuclei(AGNs) are found to be red and dust-obscured. They are believed to be in an early dusty stage of AGNs evolution or affected by dust torus in the direction of line of sight. However, optical spectrum is affected by dust extinction, making it difficult to study their properties, such as FWHM and luminosity. In order to reveal the mass of central Black Hole(BH) in red AGN, we establish a new BH mass estimator for typical type1 AGNs using Near InfraRed(NIR) hydrogen line($P_{\alpha}$ and $P_{\beta}$), since these lines are at longer wavelength, less affected by dust extinction than optical hydrogen lines, such as $H_{\alpha}$ and $H_{\alpha}$. To derive the new empirical formula, we use a sample of well-known 36 AGN with a wide BH mass range of $10^6-10^9\;M_{\odot}$, where $M_{BH}s$ are estimated by reverberation mapping method and single epoch method. The $P_{\alpha}/P_{\beta}$ luminosities and FWHMs are derived by analyzing IRTF NIR spectra or taken from literature values. We show that luminosities and FWHMs of these lines correlate well with those of Balmer lines. Suggesting that Paschen and Balmer broad lines are originated from same region. Finally, we present the new $M_{BH}$ formula that are based on $P_{\alpha}/P_{\beta}$ luminosity and FWHM. We hope that our result will be used for investigating red AGNs.

• Herbal Formula Science
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• v.25 no.2
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• pp.193-207
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• 2017

Objectives : This study was designed to investigate anti-obesity effects of DF in a ob/ob mouse model. Methods : Fifteen-week-old ob/ob mice were divided into four groups: a normal lean group given a standard diet, an ob/ob control group given a standard diet, and DF(1) and DF(2) groups given a standard diet with DF(1) (300 mg/kg), and DF(2) (600 mg/kg), respectively. After 10 weeks of treatment, body weight gain, feeding efficiency ratio, blood lipid markers, fat weight and histology were examined. Results : Body weight gain and fat mass were significantly decreased in DF(1) and DF(2) groups compared with control. The extent of decreases was eminent in DF(2) group. Feeding efficiency ratio were significantly decreased in DF(2) group compared with control. Consistent with their effects on body weight gain and fat mass, circulating concentrations of LDL, total cholesterol, free fatty acid, and insulin were decreased in DF(2) group compared with control. The size of adipocytes were significantly decreased by DF(2) compared with control. Consistent with their effects on body weight gain, hepatic lipid accumulation and liver weights were reduced in DF compared with control. Conclusions : In conclusion, these results suggest that DF not only decrease feeding efficiency ratio, and blood anti-obesity biomarkers, but also reduce fat mass, contributing to the improvement of obesity. DF also inhibits hepatic lipid accumulation.

• Transactions of the Korean Society of Automotive Engineers
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• v.19 no.1
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• pp.25-31
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• 2011

The purpose of the study is to enhance the vehicle handling stability of the PACE formula vehicle. Required data for the dynamic analysis of the vehicle are as follows: Mass, moment of inertia, and tire's dynamic properties. Mass and moment of inertia data were calculated using Siemens NX 5.0 which results were verified with VIMF measurements of GMDAT. Dynamic data for the tire were supplied by Kumho Tire. Aerodynamic forces play an important role in the formula vehicle which forces were calculated by using Fluent. Full vehicle dynamic analysis using Carsim software has been carried out to find out the improvement of the vehicle stability by changing the shapes of the rear wing.

• Bulletin of the Korean Chemical Society
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• v.28 no.5
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• pp.745-750
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• 2007

An isotope dilution-liquid chromatography/tandem mass spectrometric method was developed as a candidate reference method for the accurate determination of folic acid in infant milk formula. Sample was spiked with 13C5-folic acid and then extracted with phosphate buffer (pH 6) solution. The extract was further cleaned up by deproteinization followed by a C18 solid-phase extraction cartridge. The extract was analyzed by using LC/ ESI/MS/MS with selectively monitoring the collisionally induced dissociation channels of m/z 442 → m/z 295 and m/z 447 → m/z 295, which are the neutral glutamyl loss from the [M+H]+ ions of folic acid and 13C5-folic acid, respectively. LC/MS/MS chromatograms showed substantially reduced background from chemical noises compared to LC/MS chromatograms. Repeatability and reproducibility studies showed that the LC/MS/ MS method is a reliable and reproducible method which can provide less than 1.5 relative percentage of method precision.