• Journal of the Korean Chemical Society
• /
• v.56 no.1
• /
• pp.115-127
• /
• 2012

This is a survey research which investigated perceptions of 85 elementary and secondary school science teachers on inter-disciplinary teaching in general. It is expected that the results of this survey will help to find out the necessity, the appropriate time, the proper approach and the obstacles of inter-disciplinary education. Results indicated that 49.5% of the teachers were aware of inter-disciplinary teaching and 61.2% of the teachers agreed with the necessity of implementing inter-disciplinary strategy. However, considering difficulties in objective assessment and burdens of college entrance exam preparation, they responded that inter-disciplinary teaching could be more appropriate and feasible to be implemented for lower graders at elementary schools than secondary school students. Of the answers to the integrated approaches, 57.6% of teachers chose the theme-based approach, and 16.5% chose the problem-based approach. When they chose the theme-based approach, they stated the reason of educational readiness. On the other hand, when they chose the problem-based approach, they stated the reason of educational obligation which assumes that a problem solving needs inter-disciplinary approach. The teachers also selected 'lack of knowledge on other subjects' and 'lack of time to prepare teaching materials' as major predicaments in implementing inter-disciplinary approach. This suggests that there needs a clear and specific teaching strategy along with a guidance to teaching materials for inter-disciplinary teaching.

• Health Policy and Management
• /
• v.16 no.2
• /
• pp.96-116
• /
• 2006

To assess the economic value of pharmaceutical therapy with Kremezin, we investigated the maximum amount of willingness-to-pay (WTP) of patients with chronic renal failure (CRF) for a hypothetical effect of Kremezin in delaying the initiation of dialysis treatments. A face-to-face survey was carried out in a sample of 141 CRF patients from 2 dialysis centers, composed of 82 hemodialysis patients, 38 peritoneal dialysis patients, and 21 non-dialysis CRF patients. Using a bidding game method with a starting point of 320,000 Won, which is the average monthly out-of-pocket payment for dialysis treatment, we asked the study subjects how much they would pay per month to receive Kremezin therapy. The mean out-of-pocket monthly WTP for Kremezin was 310,000, 430,000, and 520,000 Won (p<0.05, repeated one-way ANOVA)) when Kremezin delays the initiation of dialysis treatments by 1, 2, and 4 years. Significant correlation between the respondent's WTP and income $(r=0.266{\sim}0.368,\;p<0.05)$ confirmed the construct validity of the WTP instrument. Regression results showed that patients with a higher education, with diabetes as a major causes of CRF, and undergoing hemodialysis treatments tended to express higher WTP for Kremezin. The economic value of WTP from the perspective of patients varied from 310,000 to 520,000 Won depending on the effect size of Kremezin. The mean WTP was higher than 32,000 Won, only when the hypothetical effect of Kremezin in delaying the initiation of dialysis is for 2 years. This implies that Kremezin might be the preferred choice of therapy by CRF patients if it delays the initiation of dialysis treatment for at least 2 years.

• Journal of dental hygiene science
• /
• v.14 no.2
• /
• pp.207-213
• /
• 2014

How to eliminate health disparity to ensure health equity is one of major issues that are handled across the world. The purpose of this study was to examine any possible differences in self-rated oral health state according to socioeconomic status and the relationship between the two based on the data of the 5th National Health & Nutrition Examination Survey of 2010~2012. As for differences in self-rated oral health state according to sociodemographic characteristics, the women considered themselves to be in poorer oral health than the men. The older respondents found themselves to be in poorer oral health, and there was a tendency that the respondents who were less educated and whose household income was smaller rated their own health as worse. When a logistic regression analysis was made to determine influential factors for self-rated oral health status, the women perceived they were in better oral health than the men did, and the better-educated respondents were more likely to consider themselves healthier. Concerning disparities in self-rated health state according to income level, there were broader differences in that regard according to an increase of income. The findings of the study illustrated that there was oral health inequity according to social stratum. It's required to make a nationwide effort to promote national oral health, and appropriate support should especially be provided for disadvantaged people at the same time in order to get rid of the gap in oral health among different social classes, as there is a yawning gap between them and the other classes.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.21 no.5
• /
• pp.544-550
• /
• 1992

This study was investigated on the antitumor effects of protein-polysaccharide fraction(PPF) extracted from seaweeds such as sea-lettuce and gonpi toward sarcoma-180 cells. In the PPF extracted from these seaweeds, the polysaccharide contents of sea-lettrce and gonpi were 52.20% and 48.16%, respectively. The highest levels of constituents monosaccharides found in seaweeds was fructose. The major amino acids were aspartic acid, glutamic acid, glycine and cystein. The solid tumor growth inhibition showed the highest level of 64.55% when 50mg/kg sea-lettuce was administerated. The life prolongation effect was 18.31% at 50mg/kg of gonpi. In the effects of immunologic activity, when 50mg/kg sea-lettuce was administrated, the number of circulating leucocyte showed the highest level (65.11%). The number of total peritoneal exudate cells of the sea-lettuce administerated group was increased significantly in comparison with the control group. The hematological analysis of the experimental group was similar with that of the control group.

• Journal of radiological science and technology
• /
• v.30 no.3
• /
• pp.219-225
• /
• 2007

This study was performed for the purpose of providing basic data of the pelvic disorders through survey of the frequency of management of occurrence by major risk factor. Female pelvic mass was detected using sonography, and necessary data were collected from 604 female visitors to a obstetrics and gynecology hospital located at S-si. Female pelvic mass was uterus mass, ovarian mass, cervical cyst, endometrial disease. For the analysis, such variables as age, weight and frequency of pregnancy were chosen as risk factors. Results of the analysis and conclusions are as follows ; 1) The frequency of occurrence of the female pelvic mass is highest, as 38.9% of the component ratio, in the age of 35 to 54. It maintains high level of 35.8% even in the age of 55 and above. 2) The frequency of occurrence of the female pelvic mass increases in proportion as the weight and frequency of pregnancy increase. 3) The size of the uterus tumor has no statistical relationship with the risk factors, age, weight and frequency of pregnancy.

• Journal of the Korea Convergence Society
• /
• v.8 no.7
• /
• pp.151-158
• /
• 2017

This study explored the development and utilization strategies based on the recognition of Massive Open Online Courses(MOOC) of students and professors who are the subjects of university teaching and learning. All members of the university recognized the basic concepts of MOOC as openness, sharing, and participation positively. In the understanding and recognition level of MOOC, undergraduate and graduate students were very low but professors were relatively high. They wanted the MOOC to develop courses in the humanities, natural sciences, social sciences, technology engineering and the arts and sciences, aiming at innovation in college curricula and diffusion of unique contents. The undergraduates wanted MOOC to be able to complete the liberal arts curriculum, basic learning in other areas and extra-curriculum and the graduate students who were lifelong learners wanted MOOC to be developed and utilized for strengthening lifelong education of local citizens. Professors who are providers of high quality education and lifelong learners wanted MOOC to be used for the deepening of their major courses in order to innovate the university education and to spread unique contents. The university should support the development of various MOOCs, establish the completion system, and provide advanced and high quality online education service.

• Journal of Microbiology and Biotechnology
• /
• v.33 no.4
• /
• pp.430-440
• /
• 2023

The type three secretion system (T3SS) is a major virulence system of Pseudomonas aeruginosa (P. aeruginosa). The effector protein Exotoxin S (ExoS) produced by P. aeruginosa is secreted into the host cells via the T3SS. For the purpose of an experiment on inhibitors with regard to ExoS secretion, we developed a sandwich-type enzyme-linked immunosorbent assay (ELISA) system. Quercetin was selected because it has a prominent ExoS inhibition effect and also is known to have anti-inflammatory and antioxidant effects on mammalian cells. In this study, we investigated the effects of quercetin on the expression and secretion of ExoS using ELISA and Western blot analysis methods. The results showed that the secretion of ExoS was significantly decreased by 10 and 20 µM of quercetin. Also, popB, popD, pscF, and pcrV which are composed of the T3SS needle, are reduced by quercetin at the mRNA level. We also confirmed the inhibitory effect of quercetin on cytokines (IL-6, IL-1β, and IL-18) in P. aeruginosa-infected H292 cells by real-time polymerase chain reaction (PCR) and ELISA. Collectively, quercetin inhibits the secretion of ExoS by reducing both ExoS production and the expression of the needle protein of T3SS. Furthermore, these results suggest that quercetin has the potential to be used as an anti-toxic treatment for the inflammatory disease caused by P. aeruginosa infection.

• Applied Microscopy
• /
• v.36 no.2
• /
• pp.73-82
• /
• 2006

Major contributions has been made in cellular ultrastructure studies with the use of high voltage electron microscopy (HVEM) and tomography. Applications of HVEM, accompanied by appropriate image processing, have provided great improvements in the analysis of three-dimensional cellular structures. In the present study, structural patterns of the crystalline bodies that are distinguished in mesophyll plastids of CAM-performing Sedum rotundifolium L., have been investigated using HVEM and tomography. Tilting, and diffraction pattern analysis were performed during the investigation. The titlting was performed at ${\pm}60^{\circ}\;with\;2^{\circ}$ increments while examining serial sections ranging from 0.125 to $1{\mu}m$ in thickness. The young plastids exhibited crystalline inclusion bodies that revealed a peculiar structural pattern. They were irregular in shape and also variable in size. Their structural attributes affected the plastid morphology. The body consisted of a large number of tubular elements, often reaching up to several thousand in number. The tubular elements typically aggregated to form a fluster The elements demonstrated either a parallel or lattice arrangement depending on the sectioning angle. The distance between the elements was approximately 20nm as demonstrated by the diffraction analysis. HVEM examination of the serial sections revealed an occasional fusion or branching of elements within the inclusion bodies. Finally, a three-dimensional reconstruction of the plastid crystalline bodies has been attempted using two different image processing methods.

• Journal of Korean Society of Environmental Engineers
• /
• v.22 no.7
• /
• pp.1319-1330
• /
• 2000

Activated carbons prepared by chemical activation of organic waste sludges with $ZnCl_2$ and $K_2S$ have been studied in terms of their pore development and adsorptivity. Pore development of the carbons prepared from organic waste sludges was characterized by the nitrogen adsorption at 77K. The $ZnCl_2$-activated carbon produced by chemical activation with zinc chloride exhibited type I isotherm characteristics according to the BDDT classification, suggesting the presence of micropores formed by activation process. The isotherms of the commercial powdered activated carbon and $K_2S$-activated carbon reveal a hysteresis similar to that of type IV in BDDT classification, indicating the formation of mesopores. This result implies that the major pores of $K_2S$-activated carbon are composed of meso and micropores, and a macropores are minor. The adsorptive capacities of metal on the $K_2S$-activated carbon prepared from organic waste sludges were found to be superior to those on a commercial granular activated carbon. The Langmuir and Freundlich isotherms yield a fairly good fit to the adsorption data, indicating a monolayer adsorption of metals onto $K_2S$-activated carbon. The adsorptive capacity of the $K_2S$-activated carbon was superior to $ZnCl_2$-activated carbon for $PO_4$-P, and vice versa for $NO_3$-N. From the results of the studies reported here, it can be concluded that activated carbons with adsorptivity superior to commercial granular activated carbons can be produced from organic waste sludge using a two-step carbonization/activation procedure with zinc chloride or potassium sulfide as the activating agents.

• Journal of the Korean Society for information Management
• /
• v.17 no.3
• /
• pp.21-43
• /
• 2000

Not only the infomatmn seeking bellavmr or acadenuc sources by social scientists was analyzed bnt its eiieclive usmg method was also presented in this paper. For thc purpose, the questionnaires were prepared md admmislered lo social sacnilsin who are the profcsso~s oi a large unlverslty m Taegu, Korea. and the survey for tiler academic environment and its sateiaclion, characterislics, inforn~ahon seeking behavior of academic sources, etc. was conducted. Also, iheir research mlercsts and period, informauon s e e h g behav~or and its dfficulties, reineval melhods, and uslng rrequcncies of current issues elc. were analyzed in lliis paper. The major hdings ol the quanm.live pa on the development 01 academic sources for soaal sciencc study and t11e11 uses for education md study m !hi7 study are: (1) Socid sclenhsts preferred acquiring matenal ihrougli internet. CD-ROM, and PC, etc, lo the traditional methods; (2) They spend approxinmtciy 41 days for collecihg matend they wanl. and each of them has petty various period la collect n~atenal and acquiring methods. (standard deviation : about 35 days); (3) The cilalion kequencies of fore~gu material was hi&r than domeslic one; (4) They, social sc~entists, have a pretty hard time to access and use the theses, journal, magazinc. mmol~ches and m s r o f i , CD-ROM malerid etc. technicdly; (5) The group that has morc sat~sIaclion to thesa aud more fiequenl participant ol seminar seek [or more recen issues of a journal lhrough ihc research modcl of melag. (6) The group thal has higher positioned and 1on.a tenure o: office can access lo shorter time at period lhau the one that bas lhe lowcr and the shortcr group. Also, tutule research topic and recommcndations [or a ~ocial saentlst are proposed and suggested when using a social science material