• 한국통신학회논문지
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• 제42권2호
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• pp.413-423
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• 2017

본 논문은 실내에서 위치를 측정하기 위해 초음파와 RF 기반의 실내 측위 시스템을 제안한다. 기존의 실내 측위 방안은 시간 동기화, 시스템의 복잡도, 측위의 정확성 등의 문제가 있다. 이러한 문제를 해결하기 위해 초음파와 무선주파수(RF)를 이용한 송수신 시스템을 제안한다. 송신시스템은 한 쌍의 초음파 송신기와 RF 송신기로 구성하고, 수신시스템은 복수의 초음파 수신기들과 하나의 RF 수신기로 구성한다. 또한, 제안된 시스템이 가질 수 있는 성능의 한계를 수학적으로 분석하였다. 제안된 시스템은 시뮬레이션뿐만 아니라 아두이노 모듈을 이용하여 실제 시스템을 제작하여 측위 성능을 평가하였다. 실내 공간 $2m{\times}2m{\times}2m$에서 25개 지점의 위치를 측정한 결과, 평균 6.1cm, 표준편차 1.6cm의 성능을 보였다.

• 한국화재소방학회논문지
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• 제17권3호
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• pp.7-12
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• 2003

지하철 역과 같이 대형 개구부가 있는 공간의 화재와 제연을 조사하기 위해, 지하철 역과 유사한 구조의 4 m ${\times}$ 1 m ${\times}$ 1.5m 크기의 공간 내 50 kW의 폴리우레탄 화재에 대한 수치모사를 수행하였다. 대와류모사를 난류모델로 사용하고, 혼합분율 연소모델과 복사 유한체적법을 사용하였다. 화재 발생 후 5초부터 급배기방식과 급기방식, 배기방식의 세가지 기계 제연방식이 각각 작동했을 때 제연방식에 따른 승강장과 출입통로의 공기온도와 연기이동을 비교하였다. 제연방식 가운데 급배기방식의 제연성능이 가장 좋고 안전한 것으로 나타났다. 그러나 지하철 역에 사용되고 있는 급기방식은 급기구를 통해 공급된 공기가 고온의 연기와 혼합됨으로써 제연성능이 오히려 자연제연방식보다 불량하므로 지하철 역과 같은 구조에서는 적합하지 않음을 확인하였다.

• Journal of Gastric Cancer
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• 제1권1호
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• pp.32-37
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• 2001

Purpose: Three subgroups of stage II stomach cancer (T1N2M0, T2N1M0, T3N0M0) by UICC-TNM staging system show obvious survival difference to each other, which becomes the pitfall of the current staging system. We analyzed the survival and relapse pattern of stage II stomach cancer patients in three subgroups retrospectively to prove the need for change in staging system. Materials and Methods: From July 1989 to December 1995, curative gastric resection was performed in 1,037 patients with gastric adenocarcinoma, and among them 268 patients ($26\%$) were in stage II. The number in each of subgroups (T1N2M0, T2N1M0, and T3N0M0) were 17, 139 and 112 respectively. Survival and relapse pattern were analyzed and median follow up period was 46 months. Results: The 3-year cumulative survival rates of T1N2M0, T2N1M0, and T3N0M0 were $50\%,\;80\%,\;and\;76\%$ respectively (p=0.001). And the 3-year cumulative survival rates of T1N2M0 was comparable to those of 2 subgroups of stage IIIa (T2N2M0, T3N1M0), $47\%\;and\;45\%$ (p>0.05). Peritoneal recurrence was the most frequent in T3N0M0. And hematogenous spread was more frequent in T2N1M0 while nodal spread was more frequent in T1N2M0. Ten out of 17 cases of T1N2M0 died of recurrence. Most of them showed submucosal tumor with depressed lesion and mean tumor size was 3.3 cm. Conclusions: Up-staging of T1N2M0 should be considered because it has the lowest survival rate and the worst prognosis among the three subgroups of Stage II stomach cancer patients. In early gastric cancer patients with high-risk factors (large tumor size, invasion into the submucosal layer, and lymphatic vessel involvement), lymph node dissection and postoperative adjuvant therapy is recommended in an attempt to prevent recurrence in the form of lymph node metastasis.

• 대한수학회논문집
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• 제12권3호
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• pp.491-497
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• 1997

Let $C(F, M)$ and $C(S^{-1}F, S^{-1}M)$ be Cousin complexes for a modula M and a module $S^{-1}M$ over a commutative Noetherian ring with respect to a filtration F and a filtration $S^{-1}F$ respectively. In this paper, it is shown that there is an isomorphism between the Cousin complexes $S^{-1}C(F, M)$ and $C(S^{-1}F, S^{-1}M)$.

• 한국농림기상학회지
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• 제23권4호
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• pp.306-315
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• 2021

본 연구는 유리온실 내에서 초분광 영상을 취득하였을 때 차광 커튼과 할로겐이 DN value스펙트럼에 미치는 영향에 관한 것이다. 국립식량과학원 남부작물부 유리온실에 설치된 자동영상취득시스템을 이용하였으며 30° 기울어진 보정용 Tarp (1.4×1.4 m, 12%)를 설치한 후 하우징과 거리별(0.7~2.1 m) 영상데이터를 4가지 조건으로 3반복 취득했다. 차광 커튼과 할로겐을 모두 사용하지 않고 영상을 취득하였을 경우, 직달광부분과 그림자부분은 550 nm를 기준으로 스펙트럼의 변동성이 커졌다. 직달광부분과 그림자부분의 평균 변동계수(Coefficient of variation, CV)값은 각각 1.8%, 4.2%이며 그림자 유무에 관계없이 CV값을 계산 할 경우 12.5%로 증가되었다. 차광 커튼을 사용하지 않고 할로겐만을 이용한 경우 직달광부분과 그림자 부분의 CV 값은 2.6%, 10.6%이고 그림자 유무에 관계없이 CV 값을 계산할 경우 11.2%로 나타났으며 하우징과 거리에 따른 할로겐 보광량 차이로 인해 스펙트럼 변화폭이 증가되었다. 차광커튼만을 사용한 경우 CV 값은 1.6%이며 직달광과 그림자부분의 구분이 사라졌다. 차광 커튼과 할로겐을 모두 사용한 경우 하우징과 거리에 따른 할로겐의 보광량 차이로 CV 값은 10.2%로 증가했다. 할로겐과 차광 커튼을 모두 사용한 영상의 높이 범위 별 CV 값을 계산하였을 때 0.1 m 범위는 1.4%, 0.2 m범위는 1.9%, 0.3 m 범위는 2.6%, 0.4 m 범위는 3.3%로 나타났다. 따라서 온실에서 표준화된 영상데이터를 취득하기 위해서는 차광 커튼을 이용해 광을 균일하게 해야하고 할로겐램프를 이용해 보광 할 경우 대상의 수직 높이가 0.2 m 미만이며 대상과 하우징의 거리가 일정하게 유지 되었을 때 유효하다고 판단된다.

• 대한의생명과학회지
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• 제12권1호
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• pp.17-22
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• 2006

The baculovirus expression system is a powerful method for producing large amounts of the human erythrocyte-type glucose transport protein, heterologously. Characterization of the expressed protein is expected to show its ability to transport sugars directly. To achieve this, it is a prerequisite to know the properties of the endogenous sugar transport system in Spodoptera frugiperda Clone 21 (Sf21) cells, which are commonly employed as a host permissive cell line to support the baculovirus replication. The Sf21 cells can grow well on TC-100 medium that contains 0.1% D-glucose as the major carbon source, strongly suggesting the presence of endogenous glucose transport system. However, unlike the human glucose transport protein that has a broad substrate and inhibitor specificity, very little is known about the nature of the endogenous sugar transport system in Sf21 cells. In order to characterize further the inhibitor recognition properties of the Sf21 cell transporter, the ability of phloretin, cytochalasin B and D-fructose to inhibit 2-deoxy-D-glucose (2dGlc) transport was examined by measuring inhibition constants $(K_i)$. The $K_i's$ for reversible inhibitors were determined from plots of uptake versus inhibitor concentration. The 2dGlc transport in the Sf21 cells was very potently inhibited by phloretin, the aglucone of phlorizin with a $K_i$ similar to the value of about $2{\mu}M$ reported for inhibition of glucose transport in human erythrocytes. However, the Sf21 cell transport system was found to differ from the human transport protein in being much less sensitive to inhibition by cytochalasin B (apparent $K_i$ approximately $10\;{\mu}M$). In contrast, It is reported that the inhibitor binds the human erythrocyte counterpart with a $K_d$ of approximately $0.12\;{\mu}M$. Interestingly, the Sf21 glucose transport system also appeared to have high affinity for D-fructose with a $K_i$ of approximately 5mM, contrasting the reported $K_m$ of the human erythrocyte transport protein for the ketose of 1.5M.

• 농업과학연구
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• 제48권1호
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• pp.21-31
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• 2021

Yeast strains are capable of hydrolyzing non-digestible saccharides, such as melibiose, raffinose, and stachyose, found in soy meal components. This study revealed the biochemical properties of fermented soybean meal during 72 hours with kefir. Starchyose and raffinose, non-digestible components, were almost digested in kefir 150 mL + soybean meal 500 g + water 70 mL and galactose was produced. Proteolysis of the soybean meal produced most of the small molecule peptides in kefir 150 mL + soybean meal 500 g + water 70 mL. The production of the vitamin B group and C were the highest in kefir 250 mL + soybean meal 500 g. The yeast number of the fermented soybean meal was 7.0 × 10⁶ CFU·mL^-1 which was the highest in kefir 250 mL + soybean meal 500 g. The lactic acid bacteria of the fermented soybean meal was the highest at 3.5 × 10⁹ CFU·mL^-1 in kefir 70 mL + soybean meal 500 g. The antioxidant effect was the highest at 57% in kefir 250 mL + soybean meal 500 g. Expression of inflammation-related cytokine (interleukin [IL]-1β, tumor necrosis factor [TNF]-α, and interleukin [IL]-6) was significantly inhibited in fermented soybean meals with different treatments. These results suggest that fermented soybean meal by kefir has an antiinflammatory and anti-oxidation activity and could be utilized in feed manufacturing, and inhydrolyzing non-digestible soy meal components.

• Journal of Microbiology and Biotechnology
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• 제34권5호
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• pp.1154-1163
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• 2024

Glucosylation is a well-known approach to improve the solubility, pharmacological, and biological properties of flavonoids, making flavonoid glucosides a target for large-scale biosynthesis. However, the low yield of products coupled with the requirement of expensive UDP-sugars limits the application of enzymatic systems for large-scale. C. glutamicum is a Gram-positive and generally regarded as safe (GRAS) bacteria frequently employed for the large-scale production of amino acids and biofuels. Due to the versatility of its cell factory system and its non-endotoxin producing properties, it has become an attractive system for the industrial-scale biosynthesis of alternate products. Here, we explored the cell factory of C. glutamicum for efficient glucosylation of flavonoids using apigenin as a model flavonoid, with the heterologous expression of a promiscuous glycosyltransferase, YdhE from Bacillus licheniformis and the endogenous overexpression of C. glutamicum genes galU1 encoding UDP-glucose pyrophosphorylase and pgm encoding phosphoglucomutase involved in the synthesis of UDP-glucose to create a C. glutamicum cell factory system capable of efficiently glucosylation apigenin with a high yield of glucosides production. Consequently, the production of various apigenin glucosides was controlled under different temperatures yielding almost 4.2 mM of APG1(apigenin-4'-O-β-glucoside) at 25℃, and 0.6 mM of APG2 (apigenin-7-O-β-glucoside), 1.7 mM of APG3 (apigenin-4',7-O-β-diglucoside) and 2.1 mM of APG4 (apigenin- 4',5-O-β-diglucoside) after 40 h of incubation with the supplementation of 5 mM of apigenin and 37℃. The cost-effective developed system could be used to modify a wide range of plant secondary metabolites with increased pharmacokinetic activities on a large scale without the use of expensive UDP-sugars.

• 천문학회보
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• 제46권2호
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• pp.76.1-76.1
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• 2021

Maemi Dual Field Telescope System (MDFTS) is a dual telescope system located at Kyung Hee University. The system consists of 0.4 m telescope and 0.1 m telescope for wide-field observation. The 0.4 m telescope provides photometric observation which covers a field of view of 21'×16'. It has been used for various purposes with Johnson-Cousins UBVRI broadband filter system, e.g., SomangNet and Intensive Monitoring Survey of Nearby Galaxies. In this poster, we present the standard calibration result for our broadband filter system. Also, we suggest a new usage of the KHAO 0.4m telescope which is narrowband photometry by demonstrating the standard calibration of H-alpha filter. For flux calibration, not only R filter but also V filter is used for compensating the central wavelength discrepancy between R filter and H-alpha filter.

• Safety and Health at Work
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• 제10권3호
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• pp.377-383
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• 2019

Objectives: Exposure to fine particles in urban air has been associated with a number of negative health effects. High levels of fine particles have been detected at underground stations in big cities. We investigated the exposure conditions in four occupational groups in the Stockholm underground train system to identify high-exposed groups and study variations in exposure. Methods: $PM_1$ and $PM_{2.5}$ were measured during three full work shifts on 44 underground workers. Fluctuations in exposure were monitored by a real-time particle monitoring instrument, pDR, DataRAM. Qualitative analysis of particle content was performed using inductively coupled plasma mass spectrometry. Nitrogen dioxide was measured using passive monitors. Results: For all underground workers, the geometric mean (GM) of $PM_1$ was $18{\mu}g/m^3$ and of $PM_{2.5}$ was $37{\mu}g/m^3$. The particle exposure was highest for cleaners/platform workers, and the GM of $PM_1$ was $31.6{\mu}g/m^3$ [geometric standard deviation (GSD), 1.6] and of $PM_{2.5}$ was $76.5{\mu}g/m^3$ (GSD, 1.3); the particle exposure was lowest for ticket sellers, and the GM of $PM_1$ was $4.9{\mu}g/m^3$ (GSD, 2.1) and of $PM_{2.5}$ was $9.3{\mu}g/m^3$ (GSD, 1.5). The $PM_1$ and $PM_{2.5}$ levels were five times higher in the underground system than at the street level, and the particles in the underground had high iron content. The train driver's nitrogen dioxide exposure level was $64.1{\mu}g/m^3$ (GSD, 1.5). Conclusions: Cleaners and other platform workers were statistically significantly more exposed to particles than train drivers or ticket sellers. Particle concentrations ($PM_{2.5}$) in the Stockholm underground system were within the same range as in the New York underground system but were much lower than in several older underground systems around the world.