• Proceedings of the Korea Information Processing Society Conference
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• 2008.11a
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• pp.288-291
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• 2008

전세계 인터넷 사용자 수가 약 12억 6천 만명에 이르며 2012년에는 17억명 이상이 인터넷을 사용할 것이라고 추정되는 가운데 웹 데이터베이스 응용에 대한 수요가 비즈니스를 포함하는 모든 분야에서 급속히 증가되고 있다. [1] 그러나 급증하는 수요에 비해 웹 응용의 생성 및 유지·보수는 대부분 수작업에 의존하기 때문에 많은 시간과 노력이 소요되고 있다. 본 논문에서 소개하는 WebAppGen은 ScriptGen과 InteraceGen으로 구성된 웹 응용 자동 생성기로서 웹 응용을 전자동으로 생성해 생산성을 향상시킨다. ScriptGen은 웹 응용에 필요한 폼들과 이 폼들을 통해 이루어지는 질의에 대해 데이터베이스와 연동하여 처리하는 웹 스크립트들을 자동생성하고 InterfaceGen은 ScriptGen을 통해 생성된 폼들을 엮어 접근하기 쉬운 트리 형태의 인터페이스를 제공한다. 상용 웹 응용 생성기들과 달리, WebAppGen은 웹 응용의 전 과정을 자동화 시킴으로써 생산성을 한 단계 더 향상시키고, 생성된 응용은 직관적인 계층구조를 가지는 트리 형태의 인터페이스를 지원한다. WebAppGen이 생성한 응용에서, 한 개의 폼은 관심의 대상인 엔티티 외에 이 엔티티와 직·간접적으로 연관된 모든 엔티티들에 대한 정보를 표현한다. 또한, WebAppGen은 생성될 응용의 기본 틀인 템플릿을 기반으로 하기 때문에 생성된 응용 및 WebAppGen 자체의 유지·보수를 용이하게 한다.

• Proceedings of the Korea Information Processing Society Conference
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• 2015.10a
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• pp.1042-1044
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• 2015

나날이 향상되고 있는 디바이스 성능과 기능에 따라 사용자가 활용할 수 있는 App의 수가 증가하고 있다. 이로 인해 사용자 입장에서 유지 및 관리해야 하는 App이 점차 많아지고 있지만 사용자의 편의성을 위해 효율적으로 분류하기 위한 연구는 많지 않다. 본 논문에서는 App을 좀 더 효율적으로 관리하기 위한 분류 방법을 제안한다.

• Korean Journal of Food Science and Technology
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• v.29 no.1
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• pp.26-31
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• 1997

Bee venom (Apis mellifera) phospholipase $A_2$ solubilized in reversed micelles containing small amount of water stabilized by surfactant could catalyze the hydrolysis of dipalmitoyl phosphatidylcholine (DPPC). A sensitive and simple high performance liquid chromatographic (HPLC) methodology of phospholipase $A_2$ assay for the hydrolysis of DPPC was developed. Kinetic analysis of the phospholipase $A_2$-catalyzed reaction was found to be possible in reversed micelles. Among the surfactants and organic solvents tested, aerosol-OT and isooctane were most effective for the hydrolysis of DPPC in reversed micelles. Optimal temperature, optimal pH, $K_{m,app.},\;V_{max.,app.}$ and activation energy were determined to be $35{\sim}40^{\circ}C$, 7.0, 8.73 mM, 2.83 units/㎎ protein and 12.31 kcal/mole, respectively. The hydrolysis activity was dependent on water content and maximum activity was obtained at R value (=[water]/[aerosol-OT]) of 10.0.

• Molecules and Cells
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• v.27 no.6
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• pp.651-656
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• 2009

The formation of ${\beta}$-amyloid peptide ($A{\beta}$) is initiated from cleavage of amyloid precursor protein (APP) by a family of protease, ${\alpha}$-, ${\beta}$-, and ${\gamma}$-secretase. Sub W, a substrate peptide, consists of 10 amino acids, which are adjacent to the ${\beta}$-cleavage site of wild-type APP, and Sub M is Swedish mutant with double mutations on the left side of the ${\beta}$-cleavage site of APP. Sub W is a normal product of the metabolism of APP in the secretary pathway. Sub M is known to increase the efficiency of ${\beta}$-secretase activity, resulting in a more specific binding model compared to Sub W. Three-dimensional structures of Sub W and Sub M were studied by CD and NMR spectroscopy in water solution. On the basis of these structures, interaction models of ${\beta}$-secretase and substrate peptides were determined by molecular dynamics simulation. Four hydrogen bonds and one water-mediated interaction were formed in the docking models. In particular, the hydrogen bonding network of Sub M-BACE formed spread over the broad region of the active site of ${\beta}$-secretase (P5-P3'), and the side chain of P2- Asn formed a hydrogen bond specifically with the side chain of Arg235. These are more favorable to the cleavage of Sub M by ${\beta}$-secretase than Sub W. The two substrate peptides showed different tendency to bind to ${\beta}$-secretase and this information may useful for drug development to treat and prevent Alzheimer's disease.

• The Journal of the Korea institute of electronic communication sciences
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• v.13 no.3
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• pp.643-650
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• 2018

This service uses beacon with BLE technology, and USER APP has priority with Anchor IPS which secures location and device. Since then, it has been linked with character beacons that can be used in various places. The character beacon which is recognized as a service is able to confirm the user's location through API key of the LBS CMS server, and receives various contents services of the UESR CMS server. The service network consists of character beacon, Anchor IPS, USER APP, LBS CMS server, and USER CMS server. The purpose of the service is to promote local tourism and local culture to tourists through local unique characters.

• Journal of Oriental Neuropsychiatry
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• v.15 no.2
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• pp.103-118
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• 2004

Objective : This experiment was designed to investigate the effect of KongJin-dan(KJD) on the Alzheimer's disease. Method : The effects of KJD on $LI-1{\beta}$, IL-6, $TNF-{\alpha}$, amyloid precursor proteins(APP), acetylcholinesterase(AChE), glial fibrillary acidic protein(GFAP) mRNA of PC-12 and THP-1 cell treated by CT105 and AChE activity, APP production of PC-12 cell lysate treated by CT105 were investigated, respectively. Results : 1. KJD suppressed $LI-1{\beta}$, IL-6, $TNF-{\alpha}$, APP, AChE, GFAP mRNA in THP-1 and PC-12 cell treated by CT105. 2. KJD suppressed AChE activity and production of APP significantly in cell lysate of PC-12 cell treated by CT105. Conclusions : This study shows that KJD might be usefully applied for prevention and treatment of Alzheimer's disease.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.2
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• pp.394-403
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• 2006

This research investigated the effect of the CMT and MCMT on Alzheimer's disease. The effects of the CMT and MCMT extract on expression of proinflammatory cytokine($IL-1{\beta}$, IL-6, $TNF-{\alpha}$) in the THP-1 cell; amyloid precursor proteins(APP), acetylcholinesterase(AChE) mRNA of PC-12 cells treated with CT105; the AChE activity and the APP production of PC-12 cell lysate treated with CT105 were investigated. The CMT and MCMT extract suppressed overexpression of $IL-1{\beta}$, IL-6, $TNF-{\alpha}$ in the THP-1 cell treated by LPS; the expression of APP, AChE mRNA in PC-12 cells treated with CT105; the AChE activity and the production of APP in PC-12 cell lysate treated with CT105 significantly. This study suggest that CMT and MCMT may be effective for the prevention and treatment of Alzheimer's disease.

• Journal of Physiology & Pathology in Korean Medicine
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• v.20 no.1
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• pp.138-148
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• 2006

This research investigated the effect of the CMT and SCMT on Alzheimer's disease. The effects of the CMT and SCMT extract on expression of proinflammatory cytokine(IL-$1{\beta}$, IL-6, TNF-$\alpha$) in the THP-1 cell; amyloid precursor proteins(APP), acetylcholinesterase(AChE) mRNA of PC-12 cells treated with CT105; the AChE activity and the APP production of PC-12 cell lysate treated with CT105 were investigated. The CMT and SCMT extract suppressed overexpression of IL-$1{\beta}$, IL-6, TNF-$\alpha$ in the THP-1 cell treated dy LPS; the expression of APP, AChE mRNA in PC-12 cells treated with CT105; the AChE activity and the production of APP in PC-12 cell Iysate treated with CT105 significantly. This study suggest that CMT and SCMT may be effective for the prevention and treatment of Alzheimer's disease.

• Proceedings of the Korea Information Processing Society Conference
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• 2014.11a
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• pp.466-469
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• 2014

기존 Window8 Style 에 대한 디지털 포렌식 연구는 윈도우 기본 애플리케이션에 대해서만 진행되어 있는 상황이고, 다른 3rd party Style App 들에 대해서만 진행되어있는 상황이다. 본 논문에서는 Window8 Style UI 의 Instant Messengers 에 대해 디지털 포렌식 분석하고 이를 통해 범인의 행동 흐름 파악 및 증거확보 매커니즘을 제시하고자 한다. 본 논문은 기존의 Window8 의 접근방법을 토대로 하여, Style App 의 사용흔적이나 내용에 대해 확인하며, 시간정보, 이미지 등 각종 애플리케이션들을 다각적으로 분석한다. 본 논문에서 제안한 접근법은 개별 App 들에 대한 정보를 효율적이고 빠르게 분석하고 사건에 대한 정보를 제공함으로써 범죄수사과정에 도움이 될 것으로 기대된다.

• Convergence Security Journal
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• v.12 no.4
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• pp.9-15
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• 2012

In recently years, repackaged malwares are becoming increased rapidly in Android smartphones. The repackaging is a technique to disassemble an app in a market, modify its source code, and then re-assemble the code, so that it is commonly used to make malwares by inserting malicious code in an app. However, it is impossible to collect all the apps in many android markets including too many apps. To solve the problem, we propose RePAD (RePackaged App Detector) scheme that is composed of a client and a remote server. In the smartphone-side, the client extracts the information of an app with low CPU overhead when a user installs the app. The remote server analyzes the information to decide whether the app is repackaged or not. Thus, the scheme reduces the time and cost to decide whether apps are repackaged. For the experiments, the client and server are implemented as an app on Galaxy TAB and PC respectively. We indicated that seven pairs of apps among ones collected in official and unofficial market are repackaged. Furthermore, RePAD only increases the average of CPU overhead of 1.9% and the maximum memory usage of 3.5 MB in Galaxy TAB.