• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2000년도 춘계학술대회논문집
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• pp.227-230
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• 2000

This paper introduces international and Korean standards related to human-related vibration. It reviews recent standards of ISO and KS and compares them. This comparison and analysis reveals that the current direction and activity in ISO is in progress and presents logical ways of updating Korean standards in the future. Finally, the current activity of upgrading Korean standards in the Korean TC 108/SC4 is introduced.

• PNF and Movement
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• 제7권1호
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• pp.17-23
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• 2009

Purpose : To provide a convenient framework for PNF practice, we reviewed the relationship between ICF framework and PNF framework. Methods : We reviewed literatures related with ICF and PNF. Results : ICF model is useful tool for physical therapist who is working in PNF to identify the interactions the components of individual's health, especially the relationship between functioning and disability. A framework for PNF is philosophy which included the concept, functional approach. It is essential to identify primary activity limitation and causal impairment in PNF field and evaluate the their relationship. The ICF model can be used to classify the examination information. Next step is to prioritize the activity limitation and then evaluate the interrelationships among each components of the ICF framework. Conclusions : ICF model guides physical therapist in PNF practice to identify patient problems and evaluate the interrelationship of components of their health. This model is logical framework to directs functional approach as PNF philosophy to be approached the goal.

• 한국수학교육학회지시리즈E:수학교육논문집
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• 제28권4호
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• pp.529-552
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• 2014

본 연구에서는 수학에서 추론의 중요성과 그 역할에 의미를 두고, 고등학교 수학 내용(문제)의 분석을 통해 학생들이 제공받는 추론의 유형이 얼마나 높은 수준, 즉 다양한 것인지에 대해 살펴보고자 한다. 현재, '수학 II' 교과목은 2009 개정에 따른 교과목들 중에서 '수학 I' 교과목을 이수한 후 선택하는 것(신이섭, 2011)으로, 중등 수학에서 가장 심도 있는 학습 내용을 다룬다고 볼 수 있다. 이러한 점에 감안하여 본 연구에서는 '수학 II' 교과목의 내용을 중심으로 Johnson, et al.(2010)의 여섯 가지 추론 유형을 재구성하여 이를 바탕으로 현행 9종의 모든 교과서에 수록된 추론 문제의 정도(비율) 및 유형을 파악하고자 한다. 이로써, 학생들에게 어느 정도의 추론 활동의 기회가 제공되고 있는지 살펴보고, 수학 수업에서의 추론 능력 신장의 긍정적 가능성을 가늠해 보고자 한다.

• 국제학술발표논문집
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• The 3th International Conference on Construction Engineering and Project Management
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• pp.747-753
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• 2009

Planning the construction for a system of bored piles in building foundation engineering is (1) to predict the time duration required to complete all the bored piles with due consideration of relevant engineering factors and site constraints; then (2) to predict the total project time generally by aggregating the predicted working duration for construction of each bored pile. The duration for construction of an individual bored pile results from analyzing various working sequences and different activity duration (such as predrilling, excavation, steelfixing, air-lifting, and concreting, etc.), which is informed by experiences and site records of previous projects. However, determining the project duration for constructing many bored piles on one site is much more complicated than adding up the time duration for individual piles. In practice, project schedules are often found to be unrealistic and incorrect during the construction stage. This is because construction planning is not based on a exhaustive and comprehensive evaluation of site factors, such as site layout plan, site constraints, quality control, environmental control, safety control and logical relationships between different trades. In this paper, we identify those factors based on a foundation engineering site in Hong Kong with ninety-seven bored piles and address their effects on uncertainties in activity time and project time.

• 한국과학교육학회지
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• 제29권1호
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• pp.1-9
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• 2009

본 연구에서는 중학교 과학교과서에서 많이 제시되는 과학 개념 모형에 대해 학생들로 하여금 단순히 읽고 지나가는 것이 아니라 주목하고 분석해 보는 시간을 갖게 하는 것이 과학 개념 학습에 어떠한 영향을 미치는지를 조사하였다. 과학 개념 모형에 좀 더 주목하고 분석해 보게 하는 방법으로 본 연구에서는 미완성 과학 개념 완성 활동과 과학 개념 모형 수정 활동을 고안하였으며, 이들 활동을 전통적 수업활동과 비교하였다. 연구 대상으로는 B광역시 소재 1개 중학교 3학년 학생 112명(3개 학급)을 표집하였다. 이렇게 표집한 3개 학급은 각각 미완성 개념 모형을 완성하는 활동, 주어진 개념 모형을 수정하는 활동, 전통적인 과학 수업 활동을 하도록 하고 그 성취도를 비교하였다. 본 연구의 결과는 첫째, 미완성 과학 개념 모형 완성활동은 전통적 과학 수업 활동에 배해 중학생들의 과학개념 학습에 효과적이라고 할 수 있다. 또한, 개념 모형 완성 활동을 통한 성취도는 학생들의 학교 성적이 높을수록 높고, 학생들의 인지 수준이 구체적 조작 단계에 있는 학생이거나 과도기에 있는 학생들이 높다. 둘째, 과학 개념 모형의 수정 활동은 전통적 과학수업 활동에 비해 중학생들의 과학 개념 학습에 효과적이라고 말하기 어렵다. 또한, 과학 개념 모형의 수정활동을 통한 성취도는 학생들의 학교 성적이 높을수록 높기는 하지만 하위 수준 학생들의 경우에는 수업 후 성취도가 높아지지 않음을 볼 때 개념 모형 수정 활동은 중학생 수준에는 적합하지 않다고 할 수 있다. 셋째, 중학교 학생들의 경우에는 미완성 과학 개념 모형의 완성 활동을 통한 수업이 과학 개념 모형 수정 활동을 통한 수업에 비해 개념 학습에 효과적이다.

• 생약학회지
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• 제32권4호통권127호
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• pp.311-315
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• 2001

The root of Astragalus membranaceus Bunge (Leguminosae), which has been used for the treatment of hypertension, chronic hepatitis, duodenal ulcers, chronic nephritis and promotion of immunity in folk remedies. Cyclooxygenase (COX-2) is responsible for the production of large amounts of proinflammatory prostaglandins (PGs) at the inflammatory site. Thus, a logical approach to the treatment of inflammatory disease should involve the inhibitors of COX-2. To develop new COX-2 inhibitors from natural products, Astragali Radix was screened by inhibiting prostaglandin $E_2(PGE_2)$ generation in the culture medium using enzyme immunometric assay. Two isoflavone glycosides, $7,2'-dihydroxy-3',4'-dimethoxyisoflavan-7-O-{\beta}-D-glucoside$ and $calycosin-7-O-{\beta}-D-glucoside$ isolated from Astragali Radix inhibited COX-2 activity.

• 한국미생물·생명공학회지
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• 제24권6호
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• pp.678-686
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• 1996

To improve the preservation of Kimchi, we isolated Lactobacillus plantarum lytic enzyme-producing strain from soil, and the enzyme was purified and characterized. From the observation of cultural and morpho- logical characteristics, the isolated strain was identified as Metarrisium anisopliae (Metschn.) Sorok. The enzyme was purified to 75-folds with 40% yields through affinity adsorption and CM-Sephadex C-50 column chromatog- raphy. The optimum pH and temperature for lytic activity are 4.0 and 40$\circ$C, respectively, and the enzyme acitvity is stable between pH 3.0 and 9.0, and up to 50$\circ$C. The enzyme is a monomeric protein with molecular weight of 40,000 daltons by SDS-PAGE and gel filtration. The enzyme is endopeptidase which breaks the peptide linkage of Lactobacillus plantarum peptidoglycan. The lytic action spectra confirmed that Leuconostoc mesenteroides, a useful strain for the fermentation of Kimchi, is not lysed by the enzyme. The enzyme activity is inhibited by N-bromosuccinimide (NBS), which probably indicates the involvement of tryptophan residue in active site of the enzyme, and also inhibited by Ag$^{+}$. The amino acid composition analysis showed that the enzyme contains more acidic amino acids than basic ones, and composition of alanine, glycine, proline and tyrosines was very high.

• The Plant Pathology Journal
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• 제20권2호
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• pp.115-126
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• 2004

The actinomycete strain PK-A41 was isolated from a soil sample from pepper fields in Ko-yang, Korea. The strain PK-A41 inhibited the mycelial growth of some plant pathogenic fungi and oomycete, Alternaria mali, Colletotrichum orbiculare, Fusarium oxysporum f.sp. lycopersici, Magnaporthe grisea, Rhizoctonia solani, and Phytophthora capsici. The presence of LL-diaminopi-melic acid in the cell wall extract and the nucleotide sequence of the 16S rDNA region of the strain PK-A41 was assigned to Streptomyces scabiei. Further morpho-logical, biochemical, and pathological analyses also confirmed the strain PK-A41 to be S. scabiei, which is pathogenic to potato tubers. The maximum antibiotic production of the strain PK-A41 was achieved when grown on the glycerol peptone broth (GPB) medium for 9 days.

• 약학회지
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• 제41권5호
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• pp.565-570
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• 1997

High levels of extracellular phospholipase $A_2$ (Plase $A_2$) associated with inflammatory process in man and animal models have been extensively reported elsew here. Thus, a logical approach to the treatment of inflammatory diseases should involve the inhibitors of Plase $A_2$. To develop new Plase $A_2$ inhibitors from natural products, two hundred crude drugs were screened using group II PLA$A_2$ inhibitory activity. Among them, methanol extract of 5 medicinal plants such as, Raphani Semen, Moutan cortex radicis, Arecae semen, Caryophylli Cortex and Betulae Cortex inhibited more than 90% of PLase $A_2$ activity at a concentration 2.5${\mu}g/ml$. Then, 10 methanol extracts sample were transferred into organic solvents, PLase $A_2$ inhibitory effects were found mainly in CHCl3 and EtoAc fractions.

• Bulletin of the Korean Chemical Society
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• 제30권11호
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• pp.2523-2531
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• 2009

Effects of some diacid, diamine and dinitro aromatic compounds on the structure and activity of adenosine deaminase (ADA) were investigated by UV-Vis spectrophotometry in 50 mM phosphate buffer at pH = 7.5 and 27 ${^{\circ}C}$ and molecular docking studies. The results showed that all tested ligands are showing inhibition; five ligands are uncompetitive and other two ligands are mixed of competitive and noncompetetive inhibitors with majority of competitive behavior. For the later case analysis was done based on competitive inhibition. Diacids have larger size and higher inhibition constant ($K_I$) relative to others. A logical correlation between calculated free energy of binding and experimental values was obtained for un-competitive. Experimental and calculated data showed that competitive inhibitors are distributed near the active site of enzyme and form several cluster of ranks, whereas uncompetitive inhibitors bind to the enzyme-substrate complex and distributed far from the active site. Results of structure-activity relationship showed that, larger, more hydrophobe, less spherical and more aromatic ligands have higher inhibition constants.