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Review on Usefulness of EPID (Electronic Portal Imaging Device) (EPID (Electronic Portal Imaging Device)의 유용성에 관한 고찰)

  • Lee, Choong Won;Park, Do Keun;Choi, A Hyun;Ahn, Jong Ho;Song, Ki Weon
    • The Journal of Korean Society for Radiation Therapy
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    • v.25 no.1
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    • pp.57-67
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    • 2013
  • Purpose: Replacing the film which used to be used for checking the set-up of the patient and dosimetry during radiation therapy, more and more EPID equipped devices are in use at present. Accordingly, this article tried to evaluated the accuracy of the position check-up and the usefulness of dosimetry during the use of an electronic portal imaging device. Materials and Methods: On 50 materials acquired with the search of Korea Society Radiotherapeutic Technology, The Korean Society for Radiation Oncology, and Pubmed using "EPID", "Portal dosimetry", "Portal image", "Dose verification", "Quality control", "Cine mode", "Quality - assurance", and "In vivo dosimetry" as indexes, the usefulness of EPID was analyzed by classifying them as history of EPID and dosimetry, set-up verification and characteristics of EPID. Results: EPID is developed from the first generation of Liquid-filled ionization chamber, through the second generation of Camera-based fluoroscopy, and to the third generation of Amorphous-silicon EPID imaging modes can be divided into EPID mode, Cine mode and Integrated mode. When evaluating absolute dose accuracy of films and EPID, it was found that EPID showed within 1% and EDR2 film showed within 3% errors. It was confirmed that EPID is better in error measurement accuracy than film. When gamma analyzing the dose distribution of the base exposure plane which was calculated from therapy planning system, and planes calculated by EDR2 film and EPID, both film and EPID showed less than 2% of pixels which exceeded 1 at gamma values (r%>1) with in the thresholds such as 3%/3 mm and 2%/2 mm respectively. For the time needed for full course QA in IMRT to compare loads, EDR2 film recorded approximately 110 minutes, and EPID recorded approximately 55 minutes. Conclusion: EPID could easily replace conventional complicated and troublesome film and ionization chamber which used to be used for dosimetry and set-up verification, and it was proved to be very efficient and accurate dosimetry device in quality assurance of IMRT (intensity modulated radiation therapy). As cine mode imaging using EPID allows locating tumors in real-time without additional dose in lung and liver which are mobile according to movements of diaphragm and in rectal cancer patients who have unstable position, it may help to implement the most optimal radiotherapy for patients.

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Ontology-based User Customized Search Service Considering User Intention (온톨로지 기반의 사용자 의도를 고려한 맞춤형 검색 서비스)

  • Kim, Sukyoung;Kim, Gunwoo
    • Journal of Intelligence and Information Systems
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    • v.18 no.4
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    • pp.129-143
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    • 2012
  • Recently, the rapid progress of a number of standardized web technologies and the proliferation of web users in the world bring an explosive increase of producing and consuming information documents on the web. In addition, most companies have produced, shared, and managed a huge number of information documents that are needed to perform their businesses. They also have discretionally raked, stored and managed a number of web documents published on the web for their business. Along with this increase of information documents that should be managed in the companies, the need of a solution to locate information documents more accurately among a huge number of information sources have increased. In order to satisfy the need of accurate search, the market size of search engine solution market is becoming increasingly expended. The most important functionality among much functionality provided by search engine is to locate accurate information documents from a huge information sources. The major metric to evaluate the accuracy of search engine is relevance that consists of two measures, precision and recall. Precision is thought of as a measure of exactness, that is, what percentage of information considered as true answer are actually such, whereas recall is a measure of completeness, that is, what percentage of true answer are retrieved as such. These two measures can be used differently according to the applied domain. If we need to exhaustively search information such as patent documents and research papers, it is better to increase the recall. On the other hand, when the amount of information is small scale, it is better to increase precision. Most of existing web search engines typically uses a keyword search method that returns web documents including keywords which correspond to search words entered by a user. This method has a virtue of locating all web documents quickly, even though many search words are inputted. However, this method has a fundamental imitation of not considering search intention of a user, thereby retrieving irrelevant results as well as relevant ones. Thus, it takes additional time and effort to set relevant ones out from all results returned by a search engine. That is, keyword search method can increase recall, while it is difficult to locate web documents which a user actually want to find because it does not provide a means of understanding the intention of a user and reflecting it to a progress of searching information. Thus, this research suggests a new method of combining ontology-based search solution with core search functionalities provided by existing search engine solutions. The method enables a search engine to provide optimal search results by inferenceing the search intention of a user. To that end, we build an ontology which contains concepts and relationships among them in a specific domain. The ontology is used to inference synonyms of a set of search keywords inputted by a user, thereby making the search intention of the user reflected into the progress of searching information more actively compared to existing search engines. Based on the proposed method we implement a prototype search system and test the system in the patent domain where we experiment on searching relevant documents associated with a patent. The experiment shows that our system increases the both recall and precision in accuracy and augments the search productivity by using improved user interface that enables a user to interact with our search system effectively. In the future research, we will study a means of validating the better performance of our prototype system by comparing other search engine solution and will extend the applied domain into other domains for searching information such as portal.

Three-dimensional magnetotelluric surveys for geothermal development in Pohang, Korea (포항지역 지열 개발을 위한 3 차원 자기지전류 탐사)

  • Lee, Tae-Jong;Song, Yoon-Ho;Uchida, Toshihiro
    • Geophysics and Geophysical Exploration
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    • v.10 no.1
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    • pp.89-97
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    • 2007
  • A three-dimensional (3D) magnetotelluric (MT) survey has been carried out to delineate subsurface structures and possible fractures, for development of low-temperature geothermal resources in Pohang, Korea. Quite good quality MT data could be obtained throughout the survey region by locating the remote reference in Kyushu, Japan, which is ${\sim}480\;km$ from the centre of the field site. 3D modelling and inversion are performed taking into account the sea effect in MT measurements near the seashore. The nearby sea in the Pohang area affects MT data at frequencies below $1\;Hz{\sim}0.2\;Hz$, depending on the distance from the seashore. The most severe sea effects were observed in the south-east parts of the survey area, closer to Youngil Bay. 3D inversion with and without the seawater constraint showed very similar results at shallow depths, roughly down to 2 km. At greater depths, however, a strong sea effect seems to form a fictitious conductive structure in ordinary 3D inversion, especially in the south-eastern part of the survey region. Comparison between drilling results and the resistivity profiles from inversions showed that five layered structures can be distinguished the subsurface beneath the target area. They are: (a) semi-consolidated mudstones with resistivity less than $10\;{\Omega}m$, which are ${\sim}300\;m$ thick in the northern part and ${\sim}600\;m$ thick in the southern part of the survey area; (b) occasional occurrence of trachybasalt and lapilli tuff within the mudstone layer has resistivity of a few tens of${\Omega}m$, (c) intrusive rhyolite ${\sim}400\;m$ thick has resistivity of several hundreds of ${\Omega}m$, (d) alternating sandstone and mudstone down to 1.5 km depth shows resistivity of ${\sim}100\;{\Omega}m$, (e) a conductive structure was found at a depth of ${\sim}3\;km$, but more geological and geophysical study should be carried out to identify this structure.

A Study on the Environment for Lowbirth Weight Infants in Neonatal Intensive Care Unit in the United States (신생아집중간호단위 환경과 저체중출생아의 반응에 대한 연구)

  • Han Kyung Ja
    • Child Health Nursing Research
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    • v.4 no.2
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    • pp.159-176
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    • 1998
  • In effort to conduct comparative study on the caregiving environment of Neonatal Intensive Care Unit(NICU) in both U. S and Korea, this study was been conducted first in the U.S. Purpose : The purpose of this study is to identify the physical environment and direct caregiving practices to lowbirth weight infants in NICU in the US. It also aims to examine the NICU outcome status and behavioral reponses of lowbirth weight infants. Methods : A study design using descriptive and inferential statistics was been conducted through an observational, field method. A sample of 15 preform infants admitted to NICU were recruited for the study. The subjects were those with birth weight between 1,000 gm to 1,500 gm, born at the gestation period of 27 to 33 weeks, and without any chromosomal or other genetic anomalies, major congenital infections, or maternal illness. Thirty minutes observation(three times of ten minutes of continuous observation)of the infant's behavior and physiological status, and an four-hour observation of the physical environment and direct care giving procedures were been conducted on the 3rd and 10th day after birth, and on the day of discharge from the NICU or at 34weeks postconception. The data to be collected were in four areas : the demograghic characteristics of the infants, the physical environment and care giving procedures, the frequency of the infant's designated behavior and physiological response, and NICU outcome variables. A descriptive analysis and Kruskal-Wallis, Pearson r were been applied according to variable characteristics. Results : 1. Mother's mean age was 29.47. The sample consisted of 6 males and 9 females. Mean gestational ages were 29.17 weeks. Mean birth weight was 1236.33g. Mean Apgar scores at one minute were 6.6, and 7.8 at five minutes. 2. The location for the incubator was in the distance from the light, X-ray screens and nursing station, in proximity to side-lamp, telephone and faucet on the third day after birth. The location for the incubator was in the distance from the light and radio on the tenth day and in proximity to nursing station on the day of dischage from the NICU or at 34weeks postconception. 3. Nesting was the most applying aids to the infants. And foot roll, shielding and plastic frame were frequently using by nurses for facilitating well modulated restful posture. 4. There were statistically significant changes in the patterns of physical environment included locating the infant's incubator and bedding, specific aids to self regulation on the 3rd and 10th day after birth, and on the day of discharge from the NICU or at 34weeks postconception. 5. Statistically significant changes were not appeared in the patterns of direct caregiving procedure to the infants included stress inducing or reducing manipulations on the 3rd and 10th day after birth, and on the day of discharge from the NICU or at 34weeks postconception. 6. The stress response of the infants in NICU were significantly reduced as the infants grow older. 7. There were not statistically significant correlation between the physical envronment and the stress responses of the infants in NICU. 8. There were statistically significant correlation between the direct caregiving procedure to the infants and the stress response of the infants in NICU in the second and third observation on the day three. 9. Average weight gain per day from birth to discharge was 38.73g, number of days in the hospital was 42.60, number of days before bottle feeding was 3.6. Postconception age starting bottle feed ing was 31/sup +5/ weeks. Number of days on mechanical ventilator was average 7.64, 11.42 was an average number of days of oxygen need. Conclusion : It, thus, appears that to minimize the sensorymotor stimulation for the low birthweight preterm infant in NICU, manipulation of care giving practices to the babies whatever the stress inducing or reducing procedures, have to be limited in the immediate early stage after birth. And it needed to be reexamine to identify the appropriate and specific physical environment and the patterns of direct caregiving to the low birthweight preform infant as the infants grow older in NICU.

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The Design of Smart-phone Application Design for Intelligent Personalized Service in Exhibition Space (전시 공간에서 지능형 개인화 서비스를 위한 스마트 폰 어플리케이션 설계)

  • Cho, Young-Hee;Choi, Ae-Kwon
    • Journal of Intelligence and Information Systems
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    • v.17 no.2
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    • pp.109-117
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    • 2011
  • The exhibition industry, as technology-intensive, eco-friendly industry, contributes to regional and national development and enhancement of its image as well, if it joins cultural and tourist industry. Therefore, We need to revitalize the exhibition industry, as actively holding an exhibition event. However, to attract a number of exhibition audience, the work of enhancing audience satisfaction and awareness of value for participation should be prioritized after improving quality of service within exhibition hall. As one way to enhance the quality of service, it is thought that the way providing personalized service geared toward each audience is needed. that is, if audience avoids the complexity in exhibition space and it affords them service to enable effective time and space management, it will improve the satisfaction. All such personalized service affordable lets the audience's preference on the basis of each audience profile registered in advance online grasp. and Based on this information, it is provided with exhibition-related information suited their purpose that is the booth for the interesting audience, the shortest path to go to the booth and event via audience's smart phone. and it collects audience's reaction information, such as visiting the booth, participating the event through offered the information in this way and location information for the flow of movement, the present position so that it makes revision of existing each audience profile. After correcting the information, it extracts the individual's preference. hereunder, it provides recommend booth and event information. in other words, it provides optimal information for individual by amendment based on reaction information about recommending information built on basic profile. It provides personalized service dynamic and interactive with audience. This paper will be able to provide the most suitable information for each audience through circular and interactive structure and designed smart-phone application supportable for updating dynamic and interactive personalized service that is able to afford surrounding information in real time, as locating movement position through sensing. The proposed application collects user‘s context information and carrys information gathering function collecting the reaction about searched or provided information via sensing. and it also carrys information gathering function providing needed data for user in exhibition hall. In other words, it offers information about recommend booth of position foundation for user, location-based services of recommend booth and involves service providing detailed information for inside exhibition by using service of augmented reality, the map of whole exhibition as well. and it is also provided with SNS service that is able to keep information exchange besides intimacy. To provide this service, application is consisted of several module. first of all, it includes UNS identity module for sensing, and contain sensor information gathering module handling and collecting the perceived information through this module. Sensor information gathered like this transmits the information gathering server. and there is exhibition information interfacing with user and this module transmits to interesting information collection module through user's reaction besides interface. Interesting information collection module transmits collected information and If valid information out of the information gathering server that brings together sensing information and interesting information is sent to recommend server, the recommend server makes recommend information through inference with gathered valid information. If this server transmit by exhibition information process, exhibition information process module is provided with user by interface. Through this system it raises the dynamic, intelligent personalized service for user.

A Study on the Landscape Symbolism of Tongdo-palkyung and It's Narrative Structure (통도팔경(通度八景)의 경관상징성(景觀象徵性)과 서사구조(敍事構造))

  • Rho, Jae-Hyun
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.28 no.1
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    • pp.27-37
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    • 2010
  • This study tries to illuminate the features and values of the Buddhist temple Palkyung by closely examining the forms, structures, and meanings of Tongdo-palkyung(通度八景) handed down at Tongdosa Temple, the best among Korea's Buddhist temples with its three treasures of Buddha, law of Buddha and Buddhist monks. The findings of this study can be summarized as the following. First of all, it reveals the meaning of the geographical name Yeongchuksan(靈鷲山), located to the west of Tongdosa, and a spectacular sight spread like an eagle's spread wings, as well as its location and spatial features. In particular, the arrangement features of a number of attached hermitages clearly show Yeongchuksan's world as being a temple with buddhist treasures. The multi-layered unfolding and centripetal intention of the scenery can be perceived through the shape of the Sshangryongnongju(雙龍弄珠形), around Tongdosa and the feature of the enclosed landscape encircling the steps of Hyeolcheo(穴處) Geumganggyedan. The substances and components of Tongdopalkyung include sound-based spectacles derived from Beoneumgu(梵音具) creating sounds related to religious rituals to enlighten and redeem mankind, such as Yeongji(影池: a holy pond with shadow reflections), drum sounds, and bell sounds along with physical features like pine trees, Dae(臺), waterfalls, Dongcheon (洞天), and a glow in the sky. On the other hand, Palkyung's geographical arrangements exhibit a circular spatial formation based on the main motif as Buddhist symbolism, beginning with the 'Gukjangsangseokpyo(國長生石標)' awakening the territoriality of Tongdosa and locating the first scene 'Mupunghansong(舞風寒松)' in its introductory area, with the features of water, bridge, pine grove, and Iljumun(gate) to stand for the influx. Six other scenes including 'Anyangdongdae(安養東臺)' are placed in the sacred precincts around Daeungjeon and Geumganggyedan while the glow of sunset at 'Danjoseong' just outside the domain closes the symbolic circular formation of the Tongdopalkyung, which coincides with the development of the Mandala figure symbolizing 'Gusanpalhae(九山八海)' centered in Sumisan(須彌山). What is more, Tongdopalkyung, while excluding primary scenic elements inside the temple, maximizes the domain of the mountain's entrance and the effects of the multi-layered mountain, mountain upon mountain, by intensifying the influx and centripetal qualities. The Tongdopalkyung analysis reveals the antithesis of four-coupled scenes conveying buddhist principles and thoughts on the basis of seasons, directions, space and time to display a narrative structural landscape when viewed from the temple's territoriality. Likewise, the characteristics and porch structures of Tongdopalkyung are tools and language of symbols to both externally strengthen the temple's territoriality and to internally, maximize the desires to the Land of Happiness as well as intensify religious wishes and the Mandala's multi-layered qualities through the meanings of time and space.

Hypersensitive Large Intestine Syndrome in Hyungsang Medicine (과민성대장증후군의 형상의학적 고찰 -동의보감(東醫寶鑑)을 중심으로-)

  • Choi Byung-Tae;Choi Yung-Hyun;Han Jin-Soo;Lee Yong-Tae
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.5
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    • pp.1129-1136
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    • 2005
  • The writer reports the conclusions gained from study about the cause of the hypersensitive large intestine syndrome with Dongeuibogam as the central figure through researching the disharmony among Body Essence, Vital Energy, Mentality, and Blood, mutual action of five viscera and six bowels, and external shapes. The hypersensitive large intestine syndrome is generally chronic and recurred in many cases, so it is more efficacious than symptomatic to treat according to find the contradictions of individual shapes. The shapes and cases suffering frequently the hypersensitive large intestine syndrome are Gi-kwa and Sin-kwa, having a long nose, having a bruised spot on Triple warmer, man with inclined mouth, Taeeum type, man with congested fluids, man with colic symptoms. The hypersensitive large intestine syndrome in Oriental medicine is recognized of diarrhea, constipation, abdominal pain, abdominal distention and fullness caused by seven emotions. In Dongeuibogam it can be found out the similarity in depressive symptoms due to disorder of Gi, stagnation of Gi, dysphasia due to disorder of Gi, diarrhea due to disorder of Gi, fullness of due to Gi, diarrhea due to phlegm-retention, retention of undigested food, immoderate drinking, hypo-function of the spleen, or deficiency, abdominal pain from colic symptom, and difficulty in defecation and urination, internal injury, diarrhea due to weakness and fatigue. If the Jung, Gi, Sin, and Hyul composed the human body is broken harmony, the function of large intestinal transmission would be fallen, so similar symptoms like the hypersensitive large intestine syndrome are gotten. Especially Gi-kwa suffers diarrhea, constipation abdominal pain, and abdominal distention and fullness due to depressive symptoms from disorder of Seven emotions or Seven Gi. And Sin-kwa suffers from the hypersensitive large intestine syndrome due to emotional restlessness having an influence on rhythmic movement of abdomen. Examining between five viscera and six bowels and the hypersensitive large intestine syndrome, Liver cannot disperse well having influence on mutual relation of Liver-Large intestine, Heart reduces the function of defecation and urination not to control the seven emotions, Lung having exterior and interior relation with intestine has an influence on primordial energy and let the main symptoms occur, Spleen circulating the body fluid let the main symptoms occur due to malfunction of circulation, Kidney locating in lower part of the body has deep connection with intestine, so let the disorder. Urinary bladder is connected with intestine in moisture metabolism, Stomach is connected in receive and transmission, Small intestine is connected in absorption and excretion, from small intestine pain disturbing the abdominal movement, Samcho managing the catharsis of lower heater if declined its function causes the hypersensitive large intestine syndrome. The colic symptoms of Front private parts which disorder in lower abdomen give rise to abdominal pains, difficulty in defecation and urination due to Cold are similar to the hypersensitive large intestine syndrome. The treatments of applying the shapes of colic syndrome advocated by Master Park can be efficacious cure in clinic. Researching after the clinical cases of Master Park advocating Hyungsang medicine, we came to know that plenty of prescriptions of internal injury are applied and take good effects.

Usefulness of DFOV Changes in Pediatric PET/CT Image Reconstruction (PET/CT에서 소아환자 영상 재구성 시DFOV 변화의 유용성)

  • Choi, Sung-Wook;Choi, Choon-Ki;Lee, Kyoo-Bok;Seok, Jae-Dong
    • The Korean Journal of Nuclear Medicine Technology
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    • v.12 no.3
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    • pp.171-175
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    • 2008
  • Purpose: There have been something difficulties in locating focuses and quantitative analysis in case of pediatric patients because of the relatively small body compared to adults. This author of this study, therefore, evaluated the usefulness of DFOV (Display Field Of View) according to its changes in PET/CT image reconstruction by means of the phantom experiment and pediatric patients examination. Materials & Methods: 0.023 MBq/cc of $^{18}F$-FDG was put into the uniform NU2-94 phantom, and then emission scan was acquired for 10 minutes. For reconstruction, DFOV values were changed to 50, 45, 40, 35, 30, and 25 cm respectively. As for patient images, 20 patients who were diagnosed as the one or suspicion of the children tumor are targeted from Oct 2007 to Jan 2008. For image reconstruction, 50 cm was the basis of DFOV, and the value was adjusted to DFOV 45 cm to 25 cm respectively. In the phantom and the reconstruction image of pediatric patients, the changes in pixel size and $SUV_{max}$ according to DFOV changes were analyzed. Results: As DFOV decreased to 50, 45, 40, 35, 30, and 25 cm by means of the phantom, the pixel size was changed to 3.906, 3.515, 3.125, 2.734, 2.343, and 1.953 mm respectively. Besides, as a result of reconstruction DFOV in images of pediatric patients to 50, to 25 cm, the different values of $SUV_{max}$ are shown as 3.3, 7.3, 12, 14, 18% and 2.6, 4.3, 5.0, 7.0, 10.0% on respectively when 50 cm was the standard. Conclusion: In $SUV_{max}$ using the phantom, as DFOV decreased every 5 cm, the mean value gradually increased. With 50 cm as the standard, the increase rates were 3.7, 6.5, 11.2, 19.5, and 32.1% respectively. As for pediatric patients image too, as DFOV decreased, the rates increased as in the phantom experiment. In image reconstruction, since DFOV decrease regardless of matrix size change reduced the pixel size, the image quality can be improved. This would be more useful than reconstruction and enlarge images of pediatric patients in the same way of examining adults. However, when the value of 35 cm DFOV was applied, this may result in truncated artifact, and thus the application should be properly controlled. Change of DFOV may produce better image for pediatric patients, but changes of SUV values according to DFOV change should be considered in reading.

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The Contact Metamorphism Due to the Intrusion of the Ogcheon and Boeun granites (옥천화강암과 보은화강암 관입에 의한 접촉변성작용)

  • 오창환;김창숙;박영도
    • The Journal of the Petrological Society of Korea
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    • v.6 no.2
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    • pp.133-149
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    • 1997
  • In the metapelites around the Ogcheon granite, the metamorphic grade increases from the biotite zone through the andalusite zone to the sillimanite zone towards the intrusion contact. In the metabasites around the Boeun granite, the metamorphic grade increases from transitional zone between the greenchist and amphibolite facies through the amphibolite facies to the upper amphibolite facies towards the intrusion contact. In the Doiri area locating near the intrusion contact of the Boeun granite, sillimanite- and andalusite-bearing metapelites are found with in 500 m away from the contact. The evidence described above indicates that the Ogcheon and Boeun granites caused low-P/T type contact metamorphism to the country rocks. The P-T condition of contact metamorphism due to the intrusion of the Ogcheon granite is $540{\pm}40^{circ}C, 2.8{\pm}0.9$ kb. The temperature condition of contact metamorphism due to the intrusion of the Boeun granite is $698{\pm}28^{\circ}C$. The wide compositional range of amphibole and plagioclase in the metabasites around the Boeun granite is due to the immisibility gab of amphibole and plagioclase and unstable relict composition resulted from an incomplete metamorphic reaction. The compositional range of stable amphibole and plagioclase decreases as a metamorphic grade increases due to a close of immiscibility gab. The thermal effect of contact metamorphism due to the intrusion of the Ogcheon and Boeun granites, are calculated using the CONTACT2 program based on a two dimensional finite difference method. In order to estimate the thermal effect of an introduced pluton, a circle with 10 km diameter and a triangle with 20 km side are used for the intrusion geometries of the Ogcheon granite and the Boeun granite, respectively. The results from the field and modeling studies suggest that the intrusion temperatures of the Ogcheon granite close to $800^{\circ}C$ and the intrusion temperature of the Boeun granite is higher than $1000^{\circ}C$. However, the intrusion temperatures can be lower than the suggested temperature, if the geothermal gradient prior to the intrusion of the Ogcheon and Boeun granites was higher than the normal continental grothermal gradient.

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Regulation of xylA Gene Expression in Escherichia coli (대장균에서 xylA 유전자의 발현조절)

  • Ghang, G-Hee;Roh, Dong-Hyun;Kang, Byung-Tae;Rhee, In-Koo
    • Applied Biological Chemistry
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    • v.39 no.6
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    • pp.430-436
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    • 1996
  • The induction by xylose and repression by glucose of xylose isomerase(XI) were investigated to elucidate the regulation for production of XI in Escherichia coli. Regulation for expression of xyIA gene which codes XI is under control of xylR which is a regulatory gene for xylose catabolism. When xyIR gene was resided in chromosome, the inductions of XI by the addition of 0.4% xylose were increased to 1.9 and 1.7-fold in case of locating on multicopy(pEX202/DH77) and low copy Plasmid(pEX102/DH77), respectively, as compared with that of xylA gene which was resided in chromosome(JM109). xyIR gene product derived from xyIR gene on chromosome might react to xylA gene on the plasmid as same as xylA gene on chromosome. In JM109 and xylA transformant; pEX202/DH77 and pEX102/DH77, the inductions of XI were completely repressed by the addition of 0.2% glucose and these catabolite repressions were derepressed by the addition of 1 mM cAMP In comparison with the addition of 0.4% xylose only for the induction XI was inductively produced 1.7 to 2-fold with the addition of xylose plus 1 mM cAMP in DM minimal media. pEX13/TP2010, xylA transformant of the deficient mutant($xyl^-,\;cya^-$; TP2010) of XI and cAMP production, did not induce XI by the addition of xylose only but induced in case of simultaneous addition of xylose and cAMP. These results show that cAMP and xylose are the indispensable effectors for the induction and derepression of Xl in E. coli.

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