• Asian Pacific Journal of Cancer Prevention
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• 제16권10호
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• pp.4297-4302
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• 2015

Background: To evaluate HPV testing by Hybrid Capture II (HCII) in conjunction with cytology in detecting the residual/recurrence disease after treatment of high-grade cervical intraepithelial neoplasia (CIN II-III) with loop electrosurgical excision procedure (LEEP). Materials and Methods: A retrospective review of 158 patients with histologically confirmed CIN II-III who underwent LEEP between January 2011 and October 2012 was conducted. Post-treatment control was scheduled at the 3rd, 6th, 12th and 18th month. All patients were followed up by Pap smear and HR-HPV genotype and viral load testing. Results: Pre-treatment, HR-HPV DNA, was detected in all specimens of the patients. At follow-up, 25 patients were diagnosed as the residual/recurrent disease during the FU visit, among whom, 16 patients with positive margin: 13 patients (52%) with HR-HPV DNA+/cytology+, 2 patients (8%) with HR-HPV DNA+/cytology-, 1 patient (4%) with cytology+/HR-HPV DNA-; 9 patients with clean margin - 5 patients (55.6%) with HR-HPV DNA+/cytology+; 2 patients (22.2%) with HRHPV DNA+/cytology-, 2 patients (22.2%) with cytology+/HR-HPV DNA-. None of them persisting HR-HPV DNA-/cytology-with positive or negative margin was identified as the residual/recurrent disease. The majority of residual/recurrent disease was detected at the 12th and 18th month FU, and there was almost no difference in the sensitivity and negative predictive value (NPV) between at the 3rd month and the 6th month FU visits. 14 residual/recurrence disease (14/46:30.4%) had pre-treatment high viral load (>5 000 RUL/PC) and 11 (11/112, 9.8%) with pre-treatment low viral load, P<0.05. Conclusions: (1) The persistence HR-HPV DNA is the root cause of the residual/recurrent disease for the women treated for high-grade CIN; the pre-treatment viral load and margin can be seen as the predictor. (2) The FU visit beginning at the 6th month post-treatment and lasting at least 24 months with the combination of cytology and HPV testing. (3) Patients with high pre-treatment HPV load, which is considered as one risk of developing the residual/recurrent disease, should be paid more attention (especially above 500RUL/PC) to by clinicians.

• Journal of Korean Neurosurgical Society
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• 제46권2호
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• pp.144-151
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• 2009

Objective: To compare two testing protocols for evaluating range of motion (ROM) changes in the preloaded cadaveric spines implanted with a mobile core type Charite$^{TM}$ lumbar artificial disc. Methods: Using five human cadaveric lumbosacral spines (L2-S2), baseline ROMs were measured with a bending moment of 8 Nm for all motion modes (flexion/extension, lateral bending, and axial rotation) in intact spine. The ROM was tracked using a video-based motion-capturing system. After the Charite$^{TM}$ disc was implanted at the L4-L5 level, the measurement was repeated using two different methods: 1) loading up to 8 Nm with the compressive follower preload as in testing the intact spine (Load control protocol), 2) loading in displacement control until the total ROM of L2-S2 matches that when the intact spine was loaded under load control (Hybrid protocol). The comparison between the data of each protocol was performed. Results: The ROMs of the L4-L5 arthroplasty level were increased in all test modalities (p < 0.05 in bending and rotation) under both load and hybrid protocols. At the adjacent segments, the ROMs were increased in all modes except flexion under load control protocol. Under hybrid protocol, the adjacent segments demonstrated decreased ROMs in all modalities except extension at the inferior segment. Statistical significance between load and hybrid protocols was observed during bending and rotation at the operative and adjacent levels (p< 0.05). Conclusion: In hybrid protocol, the Charite$^{TM}$ disc provided a relatively better restoration of ROM, than in the load control protocol, reproducing clinical observations in terms of motion following surgery.

• 한국구조물진단유지관리공학회 논문집
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• 제17권6호
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• pp.70-76
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• 2013

본 연구에서는 강거더 연속교에 대해 국내외 설계기준에 규정되어 있는 활하중으로 인한 충격계수를 실험을 통해 검증하였다. 대부분의 도로교의 설계기준에서는 도로교의 경우 충격계수를 약 0.3 정도의 값으로 규정하고 있으나, 연속교의 경우에는 명확한 규정 및 명시가 없는 상황이다. 그러므로 단순교에 적용되는 충격계수를 연속교에 동일하게 적용하는 것이 일반적이다. 이 연구에서는 현장실험을 통해 연속교의 충격계수가 단순교에 적용되는 경우와 같이 사용될 수 있는지를 검증하였다. 현장실험 결과 얻어진 충격계수는 2차선 교량에서 1대의 만재트럭이 통과했을 경우 가장 하중이 많이 작용한 거더에서 0.2 이내의 충격계수가 계측되었으며, 2개의 차선을 통시에 만재트럭이 통과한 경우 그 충격계수는 0.05 이내의 값을 얻었다.

• 비파괴검사학회지
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• 제32권6호
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• pp.637-647
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• 2012

Bridges are ones of fundamental facilities for roads which become social overhead capital facilities and they are designed to get safety in their life cycles. However as time passes, bridge can be damaged by changes of external force and traffic environments. Therefore, a bridge should be repaired and maintained for extending its life cycle. The working load on a bridge is one of the most important factors for safety, it should be calculated accurately. The most important load among working loads is live load by a vehicle. Thus, the travel characteristics and weight of vehicle can be useful for bridge maintenance if they were estimated with high reliability. In this study, a B-WIM system in which the bridge is used for a scale have been developed for measuring the vehicle loads without the vehicle stop. The vehicle loads can be estimated by the developed B-WIM system with the reaction responses from the supporting points. The algorithm of developed B-WIM system have been verified by numerical analysis.

• 대한기계학회논문집A
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• 제33권4호
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• pp.388-395
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• 2009

An accelerated fatigue test is essentially required to maintain the reliability of the actual structures of KTX under operation conditions. However, actual fatigue life cannot be obtained because the conventional fatigue tests are not adequate to the real load conditions. Moreover foreign component makers have not provided data of the loading stresses (S) versus cycles at the failure (N). In this study, we suggested a deduction method of the S-N curve for establishing an accelerating test under various load levels. Load history was acquired from the field tests. A Rainflow method was used on the cycle counting of the field load data. After that, an S-N curve was obtained through the iteration process under the condition that the damage index satisfies to 1 in the Miner's rule. The deduced S-N curve was applied to the performance evaluation of Korean-made sealed knuckles compared with imports.

• 한국공작기계학회논문집
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• 제13권6호
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• pp.127-134
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• 2004

As the result of reduction of the barrier of national economy on matters of quality assurance of weighing instruments in recently, it is considering in domestic as well as international matters. Therefore, this study is to analysis and compare with international md national measuring standards on the electric self-indicating scale, to improve the quality of electronic machine by providing a reformation plan on currently problems of domestic manufactured, and to identify to introduce in domestic criteria from international standards. I had compared KSC 1313 to OIML R 76-1 as the performance assessment items, such as metrology Properties test, static temperature test, temperature effect testing under the un-load, electronic wave disturbance test, high-tempereature and high-humidity stability test and durability test. Therefore, only one company is passed all items of the test according to the international (reference) standards, but it is possible to improve the quality in general if it should be use the load cell and electric components which is stability of temperature change in order to supplementation to the static temperature test and temperature effect testing under the un-load. It is also possible to apply in the domestic with the OIML 76-1 after correcting the design.

• 비파괴검사학회지
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• 제29권1호
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• pp.21-26
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• 2009

이차원 표면균열을 가진 재료의 모드 I 응력확대계수($K_1$)를 교류전위차법으로 효과적으로 계측할 수 있는 방법을 결정하기 위해 하중이 가해질 때 균열면을 포함한 시험편 내부 및 외부의 자속 변화 해석이 필요하여 이를 이론적 및 실험적으로 규명하였다. 이론 해석 결과 균열면 사이의 공기중 자속은 시험편에 하중을 가하여도 변하지 않았으며, 실험 결과와 일치하였다. 따라서 유도기전력을 많이 유도할 수 있도록 제작된 계측계로 측정한 하중에 따른 교류전위차 변화는 시험편의 내부 인덕턴스 변화와 시험편 내부 인덕턴스 변화와 관련된 상호 인덕턴스 변화에 의하여 발생한다.

• 비파괴검사학회지
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• 제22권2호
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• pp.125-131
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• 2002

본 연구에서는 3종류의 취성재료에 비커스 경도기를 사용하여 압축하중에 의한 신호특성과 잔류응력의 에너지 해방에 의하여 검출되는 신호특성을 조사하였다. 각 시험편에서 I영역과 III영역에서는 신호가 검출되었으나, 일정 하중이 유지되는 II영역에서는 음향방출 신호가 전혀 검출되지 않았다. 유리 시험편은 III영역에서 높은 진폭값을 가지는 신호가 검출되었고, $Al_2O_3$ 및 $Al_2O_3/SiC$ 시험편은 I영역에서 높은 진폭값을 가지는 신호가 검출되었다.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2001년도 춘계학술대회논문집A
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• pp.447-452
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• 2001

An automated system is developed to perform fatigue crack growth tests under constant effective stress intensity factor range ${\Delta}K_{eff}$. In the system, crack length and crack opening load are measured in real-time by using the unloading elastic compliance method. The system consists of two personal computers, an analogue electrical subtraction circuit, a stepping motor, a stepping motor driver, a PIO board, and the application software used to integrate the whole system. The performance of the developed system was tested and discussed performing constant ${\Delta}K_{eff}$ crack growth tests on a CT specimen of 7075-T6 aluminum alloy. The performance of the system is found to be strongly dependent on the accuracy of measurements of crack opening load. Besides constant ${\Delta}K_{eff}$ testing, the system is expected to be successfully applied for automation of various fatigue tests.

• Steel and Composite Structures
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• 제38권3호
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• pp.271-280
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• 2021

In this study, the fatigue property of U rib-to-crossbeam connections in orthotropic steel bridge (OSB) crossbeams under heavy traffic vehicle load was investigated considering the effects of in-plane shear stress. The applicability of an improved structural stress (ISS) method was validated for the fatigue behavior analysis of nonwelded arc-shaped cutout regions in multiaxial stress states. Various types of fatigue testing specimens were compared for investigating the equivalent structural stress, fatigue crack initiation positions, and failure modes with the unified standards. Furthermore, the implications of OSB crossbeams and specified loading cases are discussed with respect to the improved method. The ISS method is proven to be applicable for analyzing the fatigue property of nonwelded arc-shaped cutout regions in OSB crossbeams. The used method is essential for gaining a reliable prediction of the most likely failure modes under a specific heavy traffic vehicle load. The evaluated results using the used method are proven to be accurate with a slighter standard deviation. We obtained the trend of equivalent structural stress in arc-shaped cutout regions and validated the crack initiation positions and propagation directions by comparing them with the fatigue testing results. The implications of crossbeam spans on fatigue property are less significant than the effects of crossbeams.