• 대한방사선기술학회지:방사선기술과학
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• 제40권2호
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• pp.229-235
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• 2017

상복부초음파검사에서 간실질의 에코 음영증가와 불명확한 혈관경계 등으로 지방간을 진단하는데, 여러 연구들에 의하면 지방간 진단에 84~95%의 특이도와 60~90%의 민감도를 가지나 결과가 검사자에 의존적이어서 차이가 있을 수 있고 지방의 침윤 상태의 정량적인 측정이 불가능하다. 건강검진의 상복부초음파검사와 흉부 전산화단층촬영(computed tomography; CT) 검사를 같은 날에 시행한 수검자중 초음파검사에서 지방간을 진단 받은 환자의 흉부 전산화단층촬영 영상에서 간(Liver) Hounsfield Units(HU)를 측정하여 지방간 진단의 정확성을 연관분석 하고자 하였다. 연구대상 수검자 720명 중 가정의학과 전문의에게 검사를 받고 지방간 판정을 받은 자는 448명으로 62.2%였다. 지방간 판정자의 CT영상에서 간 HU를 측정한 결과 40 HU 이하의 측정값은 720명 중 175명으로 24.3%이며, 초음파에서 진단 받은 448명에 175명 중 173명이 포함되어 98.9%가 일치하였다. 이는 지방간을 초음파로 진단 시 검사자의 주관적 경험과 능력이 병변을 진단하는데 크게 영향을 미친 것으로 생각되며 검진 CT검사에서 간 HU를 측정하여 40 HU 이하는 영상저장을 통하여 지방간 진단 시 참고자료로 활용될 수 있을 것으로 사료된다.

• 한국방사선학회논문지
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• 제13권4호
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• pp.547-555
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• 2019

본 연구는 일반적인 간 초음파영상에서 형태학적인 분류인 간 표면, 간 가장자리, 간 실질을 점수체계로 이용하여 간 조직검사 결과의 경미한 섬유화(F1), 중증도 섬유화(F2), 심한 섬유화(F3) 및 간병변(F4)으로 나눈 섬유화 단계와 비교하여 유용성을 알아보고자 하였다. 결론적으로 일반적인 초음파 검사는 경미한 섬유화(F1)~심한 섬유화(F3)를 검출할 수 있는 민감한 예측 인자로 간 가장자리>간 실질>간 표면으로 나타났으며, 간경변(F4)를 검출할 수 있는 예측인자로는 간 실질>간 표면>간 가장자리로 나타났다. 일반적인 초음파 검사에서 각각의 변수가 아닌 3가지 변수조합을 활용한다면 간 섬유화 정도와 진행 상태를 평가하는데 더 유용할 것으로 사료된다.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제25권3호
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• pp.240-250
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• 2022

Purpose: This study aimed to examine the advantages and usefulness of transient elastography (Fibroscan^®) in diagnosing non-alcoholic steatohepatitis in children and adolescents compared to those of abdominal computed tomography and liver ultrasonography. Methods: Forty-six children and adolescent participants aged between 6 and 16 years who underwent transient elastography (Fibroscan^®) as well as liver ultrasonography or abdominal computed tomography were included. Thirty-nine participants underwent liver ultrasonography and 11 underwent computed tomography. The physical measurements, blood test results, presence of metabolic syndrome, and the degree of liver steatosis and liver fibrosis were analyzed, and their correlations with transient elastography (Fibroscan^®), abdominal computed tomography, and liver ultrasonography, as well as the correlations between examinations, were analyzed. Results: Thirty-six participants (78.3%) were boys, and the mean age was 12.29±2.57 years, with a mean body mass index of 27.88±4.28. In the 46 participants, the mean values for aspartate aminotransferase, alanine aminotransferase, and total bilirubin were 89.87±118.69 IU/L, 138.54±141.79 IU/L, and 0.77±0.61 mg/dL, respectively. Although transient elastography (Fibroscan^®) and abdominal computed tomography grading had a statistically significant positive correlation with aspartate aminotransferase and alanine aminotransferase values, the correlations between the results of grading performed by transient elastography (Fibroscan^®), abdominal computed tomography, and liver ultrasonography were not statistically. Conclusion: We confirmed that each examination was correlated with the results of some blood tests, suggesting the usefulness and possibility of diagnosis and treatment of steatohepatitis mediated by transient elastography (Fibroscan^®) in the department of pediatrics.

• 한국임상수의학회지
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• 제20권4호
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• pp.508-515
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• 2003

A 4-month-old 5.7 kg male Golden retriever with history of seizure, depression, lethargy and anorexia was referred to Veterinary Medical Teaching Hospital, Chungbuk National University. Hematologic examination revealed microcytosis and nonregenerative anemia. Serum chemical values showed increased serum ammonia (423 $\mu$mol/L), ALP (1101 U/L), r-GTP (13.9 U/L) and CPK (1454 U/L), and decreased total protein (4.9 g/dl) and BUN (1.6 mg/dl). Microhepatia was shown in survey abdominal radiographs. Color doppler ultrasonographic examination revealed dilated tortuous vein with turbulent flow within liver parenchyma. Intraoperative jejunoportography and intraoperative ultrasonography confirmed the location and size of single intrahepatic shunt vessel in the left medial liver lobe. Also, the anomalous vessel entering the caudal vena cava was identified beneath the diaphragm. The shunting vessel was ligated with using an Ameroid constrictor. General conditions, hematologic and serum chemical values resolved gradually after surgery. One month after surgery abdominal radiograph showed normal gastric axis and it was consistent whit the normal size liver. Normal echogenecity of liver and enlargement of portal vein were shown in ultrasonography. It is assumed that survey radiography and ultrasonography are useful for diagnosis of single intrahepatic shunt in a dog and especially jejunoportography vein portography and intraoperative ultrasonography are suitable for confirmation of the anatomic location and size of the shunting vessels.

• 한국임상수의학회지
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• 제18권4호
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• pp.350-353
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• 2001

The purpose of this study is to construct fundamental information about the ultrasonographic diagnosis for extrinsic and intrinsic abdominal disease. Normal ultrasonography of liver, gall bladder, spleen, kidney, urinary bladder, stomach, pylorus, duodenum, and heart of 4 cynomolgus monkey(Macaca fascicularis) were determined by use of ultrasonography. One cynomolgus monkey was autopsied at the time of euthanasia which is performed 24 hours after ultrasonography, and above mentioned organs were measured actually. In ultrasonography of cynomolgus monkey, the gall bladder was 17.5 cm long, and 6.6 cm wide. The width of spleen was 8.8 mm. The right kidney was 35.5 mm long, 23.7 mm wide, and 15.2 mm deep. The ultrasonographic measurements of the left kidney in calves was similar. The urinary bladder was 27.7 mm long, and 20.5 mm wide.

• 한국임상수의학회지
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• 제18권4호
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• pp.354-357
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• 2001

The purpose of this study is to construct fundamental information about the ultrasonographic diagnosis for extrinsic and intrinsic abdominal disease. Normal ultrasonography of liver, gall bladder, spleen, kidney, urinary bladder, stomach, pylorus, duodenum, and heart of 5 common marmoset(Callithrix jacchus) were determined by use of ultrasonography. One common marmoset was autopsied at the time of euthanasia which is performed 24 hours after ultrasonography, and above mentioned organs were measured actually. In ultrasonography of common marmoset, the gall bladder was 8.2 cm long, and 3.4 cm wide. The width of spleen was 4.3 mm. The right kidney was 22.2 mm long, 16.1 mm wide, and 9.3 deep. The ultrasonographic measurements of the left kidney in calves was similar. The urinary bladder was 8.6 mm long, and 5.0 mm wide.

• 대한방사선기술학회지:방사선기술과학
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• 제42권3호
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• pp.187-194
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• 2019

The purpose of this study was to evaluate the pathologic results of hepatic parenchyma parameters such as liver parenchyma, liver surface, liver margin and liver, portal vein, spleen size, And to evaluate the usefulness of fibrosis progression and hepatic ultrasonography. The sensitivity, specificity, positive predictive value, and prognostic value according to the stage of fibrosis and grade of inflammation were divided into two groups according to the morphologic variable "A" through ultrasound and "B" We evaluated the predictive value and predicted the variables to evaluate fibrosis in clinical diagnosis and treatment of patients with chronic liver disease. The sensitivity and specificity of hepatic fibrosis in hepatic morphologic variables and other size variables were highest in liver surface and edge. The morphologic parameters used in the evaluation of fibrosis were clinically relevant in distinguishing the fibrosis stage from the results of liver biopsy.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제24권2호
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• pp.187-196
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• 2021

Purpose: The rising prevalence of childhood obesity in the past decades has caused non-alcoholic fatty liver disease (NAFLD) to become the most common cause of pediatric chronic liver disease worldwide. This study was aimed at determining the effect of vitamin D (Vit D) on ultrasonography and laboratory indices of NAFLD and some blood biochemical indicators in children. Methods: In this interventional study liver ultrasonography was performed in 200 children with overweight and obesity. A 108 had fatty liver among which 101 were randomly divided into two groups of study (n=51) and control (n=50). The study group was treated with Vit D, 50000 U once a week whereas the control group received placebo with the same dose and package, both for 12 weeks. At the end of the intervention lab tests and ultrasound study was performed once again to evaluate the response to treatment. Results: It was found out that Vit D supplementation improved the fatty liver grade in the study group. The mean changes in hemoglobin (Hb), uric acid, highdensity lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), insulin, albumin and alanine aminotransferase (ALT) was significantly higher in the study group compared to controls (p<0.05). After the intervention and means adjustment, a significant difference was obtained in HDL-C, insulin, LDL-C and homeostasis model assessment of insulin resistance (HOMA-IR) between the two groups. Conclusion: Vit D supplementation in addition to improving the fatty liver grade in ultrasonography and increasing the blood Vit D level, increases the HDL and Hb level besides decreasing uric acid, LDL, HOMA-IR, insulin and ALT levels.

• 대한방사선기술학회지:방사선기술과학
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• 제31권2호
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• pp.135-140
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• 2008

목 적: 지방간은 복부초음파 검사상 나타나는 가장 흔한 질환으로 초음파상 지방간은 그 정도에 따라 경증, 중등도, 중증의 세 등급으로 구분하여 적용하고 있다. 본 연구는 초음파상 지방간을 세 등급으로 구분하여 적용하는 것이 어떠한 임상적 의의가 있는지 알아보고자 하였다. 대상 및 방법: 2007년 1월부터 12월까지 대전 D 검진센터에서 복부초음파 검사를 받은 2,185명 중 지방간으로 진단된 524명(남 290명, 여 234명)을 대상으로 초음파상 간실질의 에코정도, 음향감쇄정도, 간내혈관 및 횡격막이 보이는 정도에 따라 I군(경증), II군(중등도), III군(중증)의 세 등급으로 분류하고, 각 군별 비만지표, 간기능 수치 및 대사증후군과의 연관성을 남녀로 구분하여 분석하였다. 결 과: 지방간의 정도는 I군 350명(66.8%), II군 153명(29.2%), III군 21명(4.1%)이었으며, 남자는 여자에 비해 중증 지방간의 비율이 높았다. 각 군별 평균연령은 남자(46.1세, 44.5세, 39.1세), 여자(48.8세, 50.2세, 52.4세)로 남자는 심한 지방간일수록 평균연령이 낮았으며, 여자는 심한 지방간일수록 평균연령이 높았다. 비만지표, AST, ALT 및 대사증후군 유병률은 남녀 모두에서 지방간의 정도가 심할수록 유의하게 증가하였다(p < 0.05). 결 론: 초음파상 지방간을 정도에 따라 세분하여 적용하는 것은 지방간의 치료 및 경과관찰에 도움이 될 것으로 사료되며, 초음파에 의한 지방간 검사시 지방간 유무 뿐만 아니라 지방간의 심한 정도를 파악할 수 있는 세심한 검사가 요구된다. 또한 초음파상 지방간의 등급을 보다 객관적으로 구분할 수 있는 기준의 제시가 필요할 것으로 사료된다.

• 한국임상수의학회지
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• 제14권1호
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• pp.11-18
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• 1997

This study was performed to make fundamental data of ultrasonographic diagnosis for liver and duodenum disease in native Korean cattle. Ultrasonographic appearance of liver, caudal vena cava, portal vein, gall bladdr and duodenum according to the growth were determined from 6 to 13 months by monthly examinations in 9 native Korean cattle. The caudal vena cava was determined at 11th intercostal space by use of ultrasonography. The portal vein and gallbladder were determined at 10th intercostal space by use oof ultrasonography. The liver were determined at 12, 11 and 10 th intercostal space by use of ultrasonography. The liver, caudal vena cava, portal cein, gallbladder and duodenum were examinde in standing position. Ultrasonograms were obtainde with 3.5 or 5.0-MHz convex and 5.0-MHz sector transducer. The diameter of vena cava at the 6, 7, 8, 9, 10, 11, 12 and 13 months old age were 18.4, 20.6, 22.4, 25.1, 26.9, 27.3, 28.5 and 29.4 mm, respectively. The diameter of portal vein at the 6, 7, 8, 9, 10, 11, 12 and 13 months old age were 19.5, 20.6, 22.3, 24.5, 26.9, 28.1, 30.7 and 31.5 mm, respectively. The diameter of gall bladder at the 6, 7, 8, 9, 10, 11, 12 and 13 months old age were 63.2, 72.2, 75.1, 78.6, 80.5, 82.3, 84.4 and 91.1 mm, respectively. Cranial part of duodenum was identified near gall bladder by moving of hyperechoic ingesta. Descending duodenum paralleled with vertebrae is seen in the right upper flank and was adjacent to the abdominal wall, and was enveloped in the hyperechoic greater omentum, differentiating it from the jejunum and ileum. The diameter of cranial duodenum at the 6, 7, 8, 9, 10, 11, 12 and 13 months old age were 23.3, 27.9, 29.9, 32.2, 34.4, 34.5, 35.1 and 36.5 mm, respectively. The diameter of descending duodenum revealed smaller diameter than that of cranial duodenum. Calculi in gallbladder were observed by ultrasonography.