• Title/Summary/Keyword: literature evidence

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No Association between Egg Intake and Prostate Cancer Risk: A Meta-analysis

  • Xie, Bo;He, Huadong
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.9
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    • pp.4677-4681
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    • 2012
  • Objective: Egg consumption has been suggested to increase the risk of colorectal and some other cancers. The present study summarized and quantified the current evidence relating dietary intake of eggs and prostate cancer. Materials and methods: Literature searches were conducted to identify peer-reviewed manuscripts published up to July 2012. Twenty manuscripts from nine cohort studies and 11 case-control studies were identified. Summary risk estimates with 95% confidence intervals (CIs) were calculated for case-control and cohort studies separately. Results: Neither the case-control not the cohort studies showed any association of prostate cancer incidence with egg consumption (case-control studies: odds ratio 1.09, 95% CI 0.86-1.31; cohort studies: relative risk 0.97, 95% CI 0.97-1.07). The results were consistent in subgroup analysis. Furthermore, no association was observed between egg consumption and prostate cancer-specific mortality. Conclusions: Our analyses provided no evidence of a significant influence of egg consumption on prostate cancer incidence and mortality. However, more studies, particularly large prospective studies, are needed.

Regulatory T Cell Therapy for Autoimmune Disease

  • Ha, Tai-You
    • IMMUNE NETWORK
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    • v.8 no.4
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    • pp.107-123
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    • 2008
  • It has now been well documented in a variety of models that T regulatory T cells (Treg cells) play a pivotal role in the maintenance of self-tolerance, T cell homeostasis, tumor, allergy, autoimmunity, allograft transplantation and control of microbial infection. Recently, Treg cell are isolated and can be expanded in vitro and in vivo, and their role is the subject of intensive investigation, particularly on the possible Treg cell therapy for various immune-mediated diseases. A growing body of evidence has demonstrated that Treg cells can prevent or even cure a wide range of diseases, including tumor, allergic and autoimmune diseases, transplant rejection, graft-versus-host disease. Currently, a large body of data in the literature has been emerging and provided evidence that clear understanding of Treg cell work will present definite opportunities for successful Treg cell immunotherapy for the treatment of a broad spectrum of diseases. In this Review, I briefly discuss the biology of Treg cells, and summarize efforts to exploit Treg cell therapy for autoimmune diseases. This article also explores recent observations on pharmaceutical agents that abrogate or enhance the function of Treg cells for manipulation of Treg cells for therapeutic purpose.

The Electropalatographic Evidence of the Korean Flap: An Intervocalic Korean Liquid Sound

  • Ahn, Soo-Woong
    • Speech Sciences
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    • v.9 no.3
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    • pp.155-168
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    • 2002
  • The intervocalic Korean liquid sound has been recognized as a flap in the studies of the Korean language. But there has been very little experimental data corroborating it. The electropalatographic (EPG) experiment was conducted to test this. The subjects were one Korean speaker and one native English speaker who had a pseudopalate and did the EPG experiment at the UCLA phonetics laboratory. The spectrographic evidence of the flaps in both the English t-flap and the Korean liquid flap was also sought. The English and Korean flaps were between mid/low back vowels so that the vowels themselves would not affect palatal contacts of the tongue. The results confirmed that the Korean liquid is realized as a flap in intervocallical position with many similar properties to English flap in both EPG and spectrographic data. The Korean initial liquid sound in borrowed words such as 'rotary' and 'radio' was also a flap. But the Korean liquid in the word-final and geminate positions was a lateral as in words 'dol ' (stone), 'dollo' (with stone), 'nal' (day) and 'nallara' (carry). The intuitive theory of the Korean liquid flap was proved by the EPG and spectrographic data.

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Breast Lipofilling: A Review of Current Practice

  • Kasem, Abdul;Wazir, Umar;Headon, Hannah;Mokbel, Kefah
    • Archives of Plastic Surgery
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    • v.42 no.2
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    • pp.126-130
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    • 2015
  • Lipofilling is a reconstructive and aesthetic technique that has recently grown in popularity and is increasingly being used in breast surgery. Previous concerns had been raised regarding its safety when used for remodelling and reconstruction of the breast; however, these concerns have since been dismissed. Over the subsequent two decades, little evidence has been found to support these early theoretical concerns, and growing numbers of proponents of the procedure are confident in its safety. Many developments and refinements in the technique have taken place in recent years, and several studies have been published regarding the safety of lipofilling in the breast. We reviewed the current literature regarding the use of different lipofilling techniques as well as the current evidence regarding the oncological safety of the procedure in patients seeking aesthetic breast enhancement and in patients requiring reconstruction after treatment for breast cancer.

Essentials of Physiotherapy after Thoracic Surgery: What Physiotherapists Need to Know. A Narrative Review

  • Ahmad, Ahmad Mahdi
    • Journal of Chest Surgery
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    • v.51 no.5
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    • pp.293-307
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    • 2018
  • Physiotherapy has recently become an essential part of enhanced recovery protocols after thoracic surgery. The evidence-based practice of physiotherapy is essential for the effective management of postoperative patients. Unfortunately, only a small body of literature has discussed the rationale of the physiotherapy interventions that are routinely implemented following thoracic surgery. Nonetheless, we can integrate the available knowledge into our practice until new evidence emerges. Therefore, in this review, the principles of physiotherapy after thoracic surgery are presented, along with a detailed description of physiotherapy interventions, with the goals of enhancing the knowledge and practical skills of physiotherapists in postoperative care units and helping them to re-evaluate and justify their traditional practices.

The Role of Similarity in the Metaphor and Simile Preference

  • Kim, Ki-Soo
    • English Language & Literature Teaching
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    • v.9 no.spc
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    • pp.61-78
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    • 2003
  • The purpose of this article is to examine the role of similarity in the metaphor and simile preference and offer empirical evidence against the equivalence view of simile and metaphor. This evidence was obtained from two experiments to examine the correlation between the similarity ratings and the preference ratings. The results suggest that Korean people choose the metaphor form when the similarity of a target and a source increases, whereas they choose the simile form when the similarity of a target and a source decreases. The results from these experiments are consistent with Chiappe and Kennedy's (1999, 2001) findings. Moreover, the experiments found that Korean people were more likely to express particular comparisons as similes over metaphors than American people.

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Craniospinal Metastasis from a Metastasizing Mixed Tumor of Salivary Gland : Unusual Presentation

  • Ye, Hyun-Hee;Cho, Chang-Won;Jeon, Mi-Young;Kim, Dae-Jo
    • Journal of Korean Neurosurgical Society
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    • v.41 no.3
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    • pp.186-189
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    • 2007
  • Metastasizing mixed tumors [MMT] of salivary glands are inexplicably metastasize maintaining benign histology. There is no pathologic and flow cytometric analysis criteria to predict the metastasis. MMT is known to metastasize by local implantation, vascular and lymphatic embolization after multiple surgery to local recurrences of primary tumor. However, multiple metastasis including cranium and spine occurred even without surgery to the primary tumor in this case. No pathological evidence of malignancy could be found in both primary and metastatic tumor. MMT is considered as an low grade malignancy based on clinical behavior rather than histologic evidence, such as low mortality rate, long delay of metastasis after primary lesion. Cranial metastasis is also extremely rare and only two cases have been reported. We report this unusual case with a literature review.

Off-label use of Psychotropic Medications in Preschool Children with Attention-deficit Hyperactivity Disorder (주의력결핍 과잉행동장애에서 허가 초과 약물 처방 : 학령전기 아동 중심으로)

  • Kim, Eui-Jung
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.22 no.2
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    • pp.74-80
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    • 2011
  • Attention-deficit hyperactivity disorder (ADHD) is a neurobehavioral disorder with an onset of symptoms before 7 years of age, often starting as early as the preschool years. The off-label use of methylphenidate (MPH) for 3- to 6-year-old preschool children with ADHD is being more common, although MPH is not licensed for use in children younger than age 6 years, in most countries. Despite the limited data, the review of the literature suggests that MPH meets evidence based criteria as beneficial and safe for carefully diagnosed ADHD preschool children. Carefully monitored administration of evidence-based psychotropic medication in preschool children with ADHD may be indicated if psychosocial treatments are ineffective.

Against a Lenition Account of Tapping: Evidence from Yonbyon Korean

  • Han, Jeong-lm;Kang, Hyun-Sook
    • Speech Sciences
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    • v.8 no.2
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    • pp.107-117
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    • 2001
  • The purpose of this study is to revisit the property of tapping, based on the data from Yonbyon Korean. Taps have been described as short segments derived from corresponding stops or trills. It is also widely assumed that tapping occurs due to lenition to minimize articulatory effort. However, Yonbyon Korean data show that taps can occur in strong as well as weak positions The results of the acoustic experiments conducted in this study show that in syllable-onset position, obstruent taps consistently appear from the underlying laterals, while in intervocalic position, sonorant taps similar to American English taps occur. The results of this study provide evidence against the uniform account of tapping as the result of lenition.

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Dry Socket Etiology, Diagnosis, and Clinical Treatment Techniques

  • Mamoun, John
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.44 no.2
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    • pp.52-58
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    • 2018
  • Dry socket, also termed fibrinolytic osteitis or alveolar osteitis, is a complication of tooth exodontia. A dry socket lesion is a post-extraction socket that exhibits exposed bone that is not covered by a blood clot or healing epithelium and exists inside or around the perimeter of the socket or alveolus for days after the extraction procedure. This article describes dry socket lesions; reviews the basic clinical techniques of treating different manifestations of dry socket lesions; and shows how microscope level loupe magnification of $6{\times}$ to $8{\times}$ or greater, combined with co-axial illumination or a dental operating microscope, facilitate more precise treatment of dry socket lesions. The author examines the scientific validity of the proposed causes of dry socket lesions (such as bacteria, inflammation, fibrinolysis, or traumatic extractions) and the scientific validity of different terminologies used to describe dry socket lesions. This article also presents an alternative model of what causes dry socket lesions, based on evidence from dental literature. Although the clinical techniques for treating dry socket lesions seem empirically correct, more evidence is required to determine the causes of dry socket lesions.