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http://dx.doi.org/10.5999/aps.2015.42.2.126

Breast Lipofilling: A Review of Current Practice  

Kasem, Abdul (The London Breast Institute, Princess Grace Hospital)
Wazir, Umar (The London Breast Institute, Princess Grace Hospital)
Headon, Hannah (The London Breast Institute, Princess Grace Hospital)
Mokbel, Kefah (The London Breast Institute, Princess Grace Hospital)
Publication Information
Archives of Plastic Surgery / v.42, no.2, 2015 , pp. 126-130 More about this Journal
Abstract
Lipofilling is a reconstructive and aesthetic technique that has recently grown in popularity and is increasingly being used in breast surgery. Previous concerns had been raised regarding its safety when used for remodelling and reconstruction of the breast; however, these concerns have since been dismissed. Over the subsequent two decades, little evidence has been found to support these early theoretical concerns, and growing numbers of proponents of the procedure are confident in its safety. Many developments and refinements in the technique have taken place in recent years, and several studies have been published regarding the safety of lipofilling in the breast. We reviewed the current literature regarding the use of different lipofilling techniques as well as the current evidence regarding the oncological safety of the procedure in patients seeking aesthetic breast enhancement and in patients requiring reconstruction after treatment for breast cancer.
Keywords
Mammaplasty; Breast neoplasms; Lipectomy; Transplantation;
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1 Semprini G, Cattin F, Zanin C, et al. About locoregional recurrence risk after lipofilling in breast cancer patients: our experience. Minerva Chir 2014;69:91-6.
2 Danikas D, Theodorou SJ, Kokkalis G, et al. Mammographic findings following reduction mammoplasty. Aesthetic Plast Surg 2001;25:283-5.   DOI
3 Kirkham JC, Lee JH, Medina MA 3rd, et al. The impact of liposuction cannula size on adipocyte viability. Ann Plast Surg 2012;69:479-81.   DOI
4 Ferraro GA, De Francesco F, Tirino V, et al. Effects of a new centrifugation method on adipose cell viability for autologous fat grafting. Aesthetic Plast Surg 2011;35:341-8.   DOI
5 Petit JY, Botteri E, Lohsiriwat V, et al. Locoregional recurrence risk after lipofilling in breast cancer patients. Ann Oncol 2012;23:582-8.   DOI
6 Czerny V. Plastischer ersatz der brustdruse durch ein lipom. Verhandl Deutsche Ges Chir 1895;24:216-7.
7 Coleman SR, Saboeiro AP. Fat grafting to the breast revisited: safety and efficacy. Plast Reconstr Surg 2007;119:775-85.   DOI
8 Lexer E. Freie fettransplantation. Dtsch Med Wochenschr 1910;36:340.
9 Peer LA. Loss of volume in human fat grafts. Plast Reconstr Surg 1950;5:217.   DOI
10 Bircoll M. Cosmetic breast augmentation utilizing autologous fat and liposuction techniques. Plast Reconstr Surg 1987;79:267-71.   DOI
11 Report on autologous fat transplantation. ASPRS Ad-Hoc Committee on New Procedures, September 30, 1987. Plast Surg Nurs 1987;7:140-1.   DOI
12 Brown FE, Sargent SK, Cohen SR, et al. Mammographic changes following reduction mammaplasty. Plast Reconstr Surg 1987;80:691-8.   DOI
13 Isaacs G, Rozner L, Tudball C. Breast lumps after reduction mammaplasty. Ann Plast Surg 1985;15:394-9.   DOI
14 Largo RD, Tchang LA, Mele V, et al. Efficacy, safety and complications of autologous fat grafting to healthy breast tissue: a systematic review. J Plast Reconstr Aesthet Surg 2014;67:437-48.   DOI
15 American Society of Plastic Surgeons. Fat transfer/fat graft and fat injection: ASPS guiding principles [Internet]. Arlington Heights, IL: American Society of Plastic Surgeons; 2009 [cited 2014 Dec 24]. Available from: http://www.plasticsurgery.org/Documents/medical-professionals/health-policy/guiding-principles/ASPS-Fat-Transfer-Graft-Guiding-Principles.pdf.
16 Agostini T, Lazzeri D, Pini A, et al. Wet and dry techniques for structural fat graft harvesting: histomorphometric and cell viability assessments of lipoaspirated samples. Plast Reconstr Surg 2012;130:331e-339e.   DOI
17 Klein JA. Tumescent technique for local anesthesia improves safety in large-volume liposuction. Plast Reconstr Surg 1993;92:1085-98.   DOI
18 Lee JH, Kirkham JC, McCormack MC, et al. The effect of pressure and shear on autologous fat grafting. Plast Reconstr Surg 2013;131:1125-36.   DOI
19 Erdim M, Tezel E, Numanoglu A, et al. The effects of the size of liposuction cannula on adipocyte survival and the optimum temperature for fat graft storage: an experimental study. J Plast Reconstr Aesthet Surg 2009;62:1210-4.   DOI
20 Ueberreiter K, von Finckenstein JG, Cromme F, et al. BEAULI: a new and easy method for large-volume fat grafts. Handchir Mikrochir Plast Chir 2010;42:379-85.   DOI
21 Smith P, Adams WP Jr, Lipschitz AH, et al. Autologous human fat grafting: effect of harvesting and preparation techniques on adipocyte graft survival. Plast Reconstr Surg 2006;117:1836-44.   DOI
22 Chung CW, Marra KG, Li H, et al. VEGF microsphere technology to enhance vascularization in fat grafting. Ann Plast Surg 2012;69:213-9.   DOI
23 Witort EJ, Pattarino J, Papucci L, et al. Autologous lipofilling: coenzyme Q10 can rescue adipocytes from stress-induced apoptotic death. Plast Reconstr Surg 2007;119:1191-9.   DOI
24 Coleman SR. Hand rejuvenation with structural fat grafting. Plast Reconstr Surg 2002;110:1731-44.   DOI
25 Munch DP. Breast augmentation with autologous fat: experience of 96 procedures with the BEAULI-technique. Handchir Mikrochir Plast Chir 2013;45:80-92.   DOI
26 Rohrich RJ, Sorokin ES, Brown SA. In search of improved fat transfer viability: a quantitative analysis of the role of centrifugation and harvest site. Plast Reconstr Surg 2004;113:391-5.   DOI
27 Li FC, Chen B, Cheng L. Breast augmentation with autologous fat injection: a report of 105 cases. Ann Plast Surg 2014;73 Suppl 1:S37-4.   DOI
28 Pulsfort AK, Wolter TP, Pallua N. The effect of centrifugal forces on viability of adipocytes in centrifuged lipoaspirates. Ann Plast Surg 2011;66:292-5.   DOI
29 Kim IH, Yang JD, Lee DG, et al. Evaluation of centrifugation technique and effect of epinephrine on fat cell viability in autologous fat injection. Aesthet Surg J 2009;29:35-9.   DOI
30 Conde-Green A, Wu I, Graham I, et al. Comparison of 3 techniques of fat grafting and cell-supplemented lipotransfer in athymic rats: a pilot study. Aesthet Surg J 2013;33:713-21.   DOI
31 Zuk PA, Zhu M, Ashjian P, et al. Human adipose tissue is a source of multipotent stem cells. Mol Biol Cell 2002;13:4279-95.   DOI
32 Khater R, Atanassova P, Anastassov Y, et al. Clinical and experimental study of autologous fat grafting after processing by centrifugation and serum lavage. Aesthetic Plast Surg 2009;33:37-43.   DOI
33 Pfaff M, Wu W, Zellner E, et al. Processing technique for lipofilling influences adipose-derived stem cell concentration and cell viability in lipoaspirate. Aesthetic Plast Surg 2014;38:224-9.   DOI
34 Matsumoto D, Sato K, Gonda K, et al. Cell-assisted lipotransfer: supportive use of human adipose-derived cells for soft tissue augmentation with lipoinjection. Tissue Eng 2006;12:3375-82.   DOI
35 Khouri RK, Eisenmann-Klein M, Cardoso E, et al. Brava and autologous fat transfer is a safe and effective breast augmentation alternative: results of a 6-year, 81-patient, prospective multicenter study. Plast Reconstr Surg 2012;129:1173-87.   DOI
36 Kolle SF, Fischer-Nielsen A, Mathiasen AB, et al. Enrichment of autologous fat grafts with ex-vivo expanded adipose tissue-derived stem cells for graft survival: a randomised placebo-controlled trial. Lancet 2013;382:1113-20.   DOI
37 Peltoniemi HH, Salmi A, Miettinen S, et al. Stem cell enrichment does not warrant a higher graft survival in lipofilling of the breast: a prospective comparative study. J Plast Reconstr Aesthet Surg 2013;66:1494-503.   DOI
38 Khouri RK, Khouri RK Jr, Rigotti G, et al. Aesthetic applications of Brava-assisted megavolume fat grafting to the breasts: a 9-year, 476-patient, multicenter experience. Plast Reconstr Surg 2014;133:796-807.   DOI
39 Ho Quoc C, Delay E. Tolerance of pre-expansion BRAVA and fat grafting into the breast. Ann Chir Plast Esthet 2013;58:216-21.   DOI
40 Rubin JP, Coon D, Zuley M, et al. Mammographic changes after fat transfer to the breast compared with changes after breast reduction: a blinded study. Plast Reconstr Surg 2012;129:1029-38.   DOI
41 Lohsiriwat V, Curigliano G, Rietjens M, et al. Autologous fat transplantation in patients with breast cancer: "silencing" or "fueling" cancer recurrence? Breast 2011;20:351-7.   DOI
42 Zocchi ML, Zuliani F. Bicompartmental breast lipostructuring. Aesthetic Plast Surg 2008;32:313-28.   DOI
43 Perez-Cano R, Vranckx JJ, Lasso JM, et al. Prospective trial of adipose-derived regenerative cell (ADRC)-enriched fat grafting for partial mastectomy defects: the RESTORE-2 trial. Eur J Surg Oncol 2012;38:382-9.   DOI
44 Panettiere P, Marchetti L, Accorsi D. The serial free fat transfer in irradiated prosthetic breast reconstructions. Aesthetic Plast Surg 2009;33:695-700.   DOI
45 Petit JY, Rietjens M, Botteri E, et al. Evaluation of fat grafting safety in patients with intraepithelial neoplasia: a matched-cohort study. Ann Oncol 2013;24:1479-84.   DOI
46 Sarfati I, Ihrai T, Duvernay A, et al. Autologous fat grafting to the postmastectomy irradiated chest wall prior to breast implant reconstruction: a series of 68 patients. Ann Chir Plast Esthet 2013;58:35-40.   DOI
47 Iannace C, Di Libero L, Manetta F, et al. Coleman lipofilling: experience of an Italian group and review of the literature. Chir Ital 2009;61:67-75.