• The Korean Journal of Physiology and Pharmacology
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• v.8 no.6
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• pp.345-349
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• 2004

Heat shock ($43^{\circ}C$ for 60 minutes) is sufficient to induce apoptosis in a wide number of cell lines. In this study, we asked whether DNA strand breaks are responsible for this phenomenon. Using the highly sensitive comet assay for DNA damage detection, we were unable to demonstrate DNA breaks immediately after heat shock in Raji human Iymphoid cells. It showed that DNA breaks were not necessary for hyperthermic apoptosis, since its activity is indicative of DNA lesions. Here, we present a suggestion that a protein(s) is the major target for heat shock apoptosis. We firstly found glycerol, which reportedly stabilizes protein structure, showed a protective effect in Raji cells against hyperthermic apoptosis. In addition, quercetin, which modulates transcription of the heat shock protein family members, enhanced apoptotic death induced by hyperthermia. Furthermore, Raji cells are protected by a pre-mild heat treatment prior to the killing dose of heat shock.

• YAKHAK HOEJI
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• v.46 no.6
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• pp.459-465
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• 2002

$\beta$-l, 3-glucans are well known to enhance the immune reactions, resulting in antitumor, antibacterial, antiviral, anticoagulatory and wound healing activities. $\beta$-1, 3-glucans have various activities depending on molecular weight, degree of branching, conformation, water-solubility and intermolecular association. However, the $\beta$-1, 3-glucans linked backbone structure is essential and $\beta$-D-glucopyranosyl units are required for immunopotentiating activities. In this study, we tested the immunophamacological activities of insoluble $\beta$-1, 3-glucan from Agrobacterium sp. R259 KCTC 10197BP and confirmed the following activities: (1) IFN-${\gamma}$ production in PBMCs in the presence or in the absence of PHA, LPS, IL-18, and IL-12; (2) the induction of various cytokines in the spleen and thymus; (3) the adjuvant effect on the antibody production; (4) the cytotoxic and antitumor effects on cell lines and ICR mice. These results strongly suggest that $\beta$-1, 3-glucan from Agrobacterium sp. R259 KCTC 10197BP possesses various immunopharmacologica1 activities.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.24 no.7A
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• pp.947-954
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• 1999

A new low phase noise Dielectric Resonator Parallel Feedback Oscillator(DRPFO) that is proposed in this paper has a simple structure so that it can be fabricated in low cost and with high performance. The proposed DRPFO is in a feedback loop oscillator configuration, which is composed of a low noise amplifier, a power amplifier, a power attenuator, a power divider and a parallel resonator feedback element that consists of a dielectric resonator coupled with two microstrip lines. The measured phase noise of DRPFO was less than -81 dBc/Hz at offset frequency 1 kHz of 10.75 GHz carrier frequency, and the frequency stability of DRPFO was less than $\pm$200 kHz over the temperature range of -40$^{\circ}$C to +60$^{\circ}$C.

• Journal of Advanced Navigation Technology
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• v.17 no.6
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• pp.658-663
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• 2013

In this paper, a microstrip line implementation using via transition and its application of multilayer compact ring hybrid coupler are presented. This transition is the sandwich structure with via hole to connect two microstrip lines in different layer. For designing a compact RF/Microwave passive circuit, the microstrip line using via-hole transition is proposed to reduce a size of microwave circuit with long transmission line. For the validation of the microstrip line with via-hole transition, the multilayer ring hybrid coupler is implemented at center frequency of 2 GHz. The measured performances are in good agreement with simulation results and about 50% size reduction compare to conventional ring hybrid coupler.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.18 no.6
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• pp.151-156
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• 2018

Because of its large differences in writing style, context-independency and high recognition accuracy requirement, free handwritten digital identification is still a very difficult problem. Analyzing the characteristic of handwritten digits, this paper proposes a new handwritten digital identification method based on combining structural features. Given a handwritten digit, a variety of structural features of the digit including end points, bifurcation points, horizontal lines and so on are identified automatically and robustly by a proposed extended structural features identification algorithm and a decision tree based on those structural features are constructed to support automatic recognition of the handwritten digit. Experimental result demonstrates that the proposed method is superior to other general methods in recognition rate and robustness.

• Journal of Society of Preventive Korean Medicine
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• v.12 no.3
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• pp.47-58
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• 2008

The anticancer and antioxidant effect of different lengths of saturated fatty acids was tested on NIH3T3 fibroblasts and human skin melanoma cellsn in this study. The cell existence rate and antioxidizing capacity and optic reservation of cells were observed. This saturated fatty acid was concentration-dependent. IC50 Concentrations in NIH3T3 fibroblasts, human skin melanoma cells and DPPH radical scavenging activity of fatty acid was increasing the order of carbochain length ; caprylic acid < lauric acid < palmitic acid < stearic acid. The reduction in cell number and morphological change in human skin melanoma cells was increasing the order of carbochain length ; caprylic acid < lauric acid < palmitic acid < stearic acid. These results suggest that carbochain length of fatty acid can be used as structure-activity relationships for anticancer and antioxidant.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.58 no.12
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• pp.2462-2467
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• 2009

This paper proposes a dual band branch line coupler (BLC) using a composite right/left handed (CRLH) transmission line. The existing dual band BLCs with open stubs require hundreds of line impedance for the open stub as the frequency bands approach to each other, so it has been almost impossible to realize them. However in the proposed BLC, a CRLH transmission line replaces the open stub with an extremely high line impedance so that the BLC circuit may be realized even two frequencies are close to each other. As an example, a dual band BLC operating at 1800MHz and 2300MHz (the frequency ratio is 1:1.28) is designed and measured. Open stubs with $560\Omega$ line impedance are replaced by CRLH transmission lines for realizing the dual band BLC. The measured performances prove that the dual band operation is well acceptable and the proposed design method is successful even the ratio between two frequencies is not around two nor more.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.23 no.6
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• pp.69-74
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• 2023

In this paper we review techniques for building and analyzing wavelets on irregular point sets in one and two dimensions. In particular we focus on subdivision schemes and commutation. Subdivision means the skill that approximates the initial lines or mesh into a tender curve or a curved surface by continuous partitioning operation. The key to generalizing wavelet constructions to non-traditional settings is the use of generalized subdivision. The first generation setting is already connected with subdivision schemes, but they become even more important in the construction of second generation wavelets. Subdivision schemes provide fast algorithms, create a natural multi-resolution structure, and yield the underlying scaling functions and wavelets we seek.

• Journal of the Korea Society of Computer and Information
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• v.8 no.1
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• pp.13-19
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• 2003

There are active researches on automated guided vehicles(AGV) generally used in flexible manufacturing system(FMS) or automated warehouse systems(AWS). Because existing AGV uses magnetic tapes, electric wire, RF or laser as guidelines, its installation and modification require a lot of money and time. The present study implemented AGV that detects paths marked with 50mm Yellow tape using a mono-color CCD camera. Because it uses color tape, it is easy and inexpensive to install and change lines. This study presented the structure of the developed AGV, the image Processing technique for detecting guidelines by ing the characteristics of color, and the result of operating AGV.

• Proceedings of the KIEE Conference
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• 2003.10a
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• pp.107-109
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• 2003

This paper was to measure the structure, piezoelectric properties of $0.03Pb(Mg_{0.5}W_{0.5})O_3$ - $0.12Pb(Sb_{0.5}Nb_{0.5})O_3$ - $0.85Pb(Zr_{0.52}Ti_{0.48})O_3$ + $0.5[wt%]MnO_2$ ceramics dropped with additive CuO after manufacturing the specimens with a general method. It is shown that X-ray diffraction pattern variation of lines (211) have tendency to move minutely by addition of additive CuO. According to dropping with Cu, the dielectric constant at 20[$^{\circ}C$] reduced to CuO 3.0[wt%]. In case of sintering at 1050[$^{\circ}C$], dielectric constant was maximum value 623.59 at CuO 1.0[wt%]. Dielectric loss was maximum value 2.7[%] at Cu 2.0[wt%] in case of sintering at 1050[$^{\circ}C$].