• Korean Journal of Digital Imaging in Medicine
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• v.12 no.1
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• pp.33-41
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• 2010

National Cancer Screening Project and Korean Society of Breast Imaging recommend that breast cancer screening should be performed on those aged 40 and above. Nevertheless, this recommendation is usually ignored by a number of medical institutions. The purpose of this study is to emphasize the necessity of an age limitation in screening mammography. Ten institutions were randomly selected and telephone inquiries about patients' age limitation and internal guidelines were set up. The 3,214 women, who underwent screening mammography through 'GE Senography 2000D' in each hospital, were classified into five groups according to age(from 20s to 40s, at intervals of 5). And then, collected data was analyzed by a radiologist in accordance with ACR-BIRADS(American College of Radiology Breast Imaging Reporting and Data System), through which breast parenchymal density and the results of analysis were categorized in order to predict the sensitivity of mammography. Information about craniocaudal-view mammograms was automatically produced by use of GE Senography 2000D, and the average glandular dose was retrospectively analyzed through the program 'Excel 2007.' Two institutions did not set the age limitation. Other seven institutions internally allowed those who wanted to receive mammography regardless of age. Approximately 99% of those aged 20 to 29 were judged as having the dense breast. In those aged 35 to 39, breast parenchymal density tended to be lower, but the fatty breast to increase. In the case of 'category-zero' that does not need additional tests, the rate of 'heterogeneously dense' and 'extremely dense' reached to 83.1% and 15.1% respectively. Regarding dense breasts, there was no sufficient information for image reading. The glandular dose, applied to 3,214, was 1.47mGy on the average. In those aged 20 to 24 who are sensitive to radiation, the average glandular dose indicated 1.59mGy. Those aged 35 and above showed the lowest value, 1.43mGy. In those aged 35 to 39, the breast tended to change from denseness to fattiness. The average glandular dose was lowest in those aged 35 and above, which suggests that screening mammography should be periodically performed on those aged 35 and above in order that breast cancer may be early detected. On the other hand, in those aged less than 35, it is difficult to analyze mammograms due to the high density of breast parenchyma, and also retakes become frequent. In particular, subjects may be exposed to excessive doses. Accordingly, it should be substituted by breast self-examination or clinical breast examination. In case of need, it is advisable to perform ultrasonography.

• Journal of Korean Society on Water Environment
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• v.26 no.3
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• pp.377-386
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• 2010

Introduction of TBELs into Korean environmental regulatory system for wastewater may require very careful considerations and appropriate modifications of the TBELs applied in US. The Korean regulations for wastewater are based on uniform regulatory criteria for wastewater effluent discharge and are quite different from the individual permit system in US. In addition, the toxic pollutants regulated in Korea are much less than those in US. Therefore, the effects of TBELs application on the pollutants reduction and the economic feasibility should be carefully assessed for different categories of wastewater sources. In this study, the applicability of TBELs for the industrial categories of Korea was discussed. The TBELs were derived for a sample category, the pulp paper paperboard manufacture, based on the previously reported analytical data from 52 facilities of the domestic pulp paper paperboard manufacture in Korea. It was suggested that the BAT effluent limitations were BOD 30 mg/L, $COD_{Mn}$ 40 mg/L, SS 40 mg/L, T-N 30 mg/L and T-P 4 mg/L and that the allowable effluent loads were $0.31{\sim}1.75kgCOD_{Mn}/ton$-products. Due to the limitation of insufficient data, there were difficult to obtain the important factors to derive more systematic and accurate limitation standards for the pollutants such as the 'Long Term Average (LTA)', the 'Product Normalized Discharge Flow (PNDF)', and the 'Variability Factor (VF)'. However, as the first trial of TBELs determination based on the all available analytical data reported, the procedure and the outcome of the study may provide valuable insight on application of TBELs in Korea.

• Journal of Environmental Science International
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• v.13 no.1
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• pp.99-107
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• 2004

This research is to determine the level of environmental pollution at a blasting construction area which is the origin of noise, vibration, and suspended particle, and to compare the results with other domestic and international standard data. This experiment is also to find out the effects resulting from blasting construction and to propose a plan that can decrease environmental pollution. The blasting construction area is a factory site which is about one and half million square meter and sewage disposal plant is about ninety thousand square meter. Both were selected as the areas for the tests to be conducted in determination test. The test to determine the level of noise, vibration, and total suspended particle was conducted thirty times around the blasting construction area by comparing measurement results and numerical analysis. However, as the test was not conducted in the laboratory but in the actual blasting construction area, it was not possible to do the test with the same exact conditions each true. Therefore, the test was not ideal as conditions could change from test to test. For the most part, the level of noise was below the standard level of 70dB. Every vibration test was under the standard limitation. For example, a house, 200m away was tested for noise and vibration and the level was found to be under the 0.2 cm/sec which is the standard for specialty designed cultural sites., i.e very low level. Also a buried oil pipeline that was 30m away also marked under 2.0cm/sec which is the norm for an industrial area. However, if there were an oil pipeline under the house, the amount of charging gunpowder per hole should be decreased compared to the amount used in the test. The test result for suspended particles under the standard limitation which is 24hour average 300$\mu\textrm{g}$/㎥ at a distance from blasting wavelength, but at detonator, total suspended particle from the blast origin exceeded the standard limitation. If explosion occurs when it detonates in the hole, most of the energy would be absorbed in the crushing of rocks, but some remaining energy would make noises and vibration inevitable. So the important thing is how to minimize the environmental pollution from the blasting. There should be regulations in order that the standard limitation is not exceeded, and to decrease the environmental pollution from the blasting.

• Biomedical Science Letters
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• v.15 no.4
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• pp.309-317
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• 2009

Occupational exposure to inorganic dusts such as coal and silica has been identified as a chronic obstructive pulmonary disease (COPD) risk factor. This risk factor causes lung inflammation and protease-antiprotease imbalance. This abnormal inflammatory response of the lung induces parenchymal tissue destruction and leads to progressive airflow limitation that is characteristics of COPD. The aim of this study was to determine the relationship of proteases such as neutrophil elastase (NE) and matrix metalloproteinase (MMP)-9 and antiproteases such as alpha-1 antitrypsin (AAT) and tissue inhibitors of metalloproteinase (TIMP)-1 with lung function. The study population contained 223 retired workers exposed to inorganic dusts. We performed lung function test, including percent of forced expiratory volume in one second ($%FEV_1$) predicted and $%FEV_1$/forced vital capacity (FVC). We analyzed serum MMP-9, AAT, TIMP-1 and plasma NE concentrations by sandwich enzyme immunoassay. NE, AAT, and TIMP-1 concentrations in workers, who had $%FEV_1$<80% predicted, were higher than those of workers who had $%FEV_1{\geq}80%$ (P<0.05). Both AAT and TIMP-1 concentrations in workers with airflow limitation were higher than those of workers with normal airflow (P<0.05). $%FEV_1$ predicted showed significant negative correlation with AAT (r=-0.255, P<0.0l), TIMP-1 (r=-0.232, P<0.01), and NE (r=-0.196, P<0.01). $%FEV_1$/FVC predicted showed significant negative correlation with NE (r=-0.172, P<0.05). From the results of stepwise multiple regression analysis about $%FEV_1$ and $%FEV_1$/FVC, significant independents were NE (r=-0.135, P=0.001) and AAT (r=-0.100, P=0.013) in $%FEV_1$, and NE (r=-0.160, P=0.014) in $%FEV_1$/FVC. In the present study, there were significant correlations between airflow limitation and protease concentration and between airflow limitation and antiprotease concentration. Serum protease and antiprotease concentrations, however, may be affected by the biological and inflammatory responses. It is necessary to evaluate specimens more reflected the effects of proteases and antiproteases in the lung such as lung tissue, bronchoalveolar lavage fluid, and exhaled breath condensate (EBC).

• Journal of Korean Society of Coastal and Ocean Engineers
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• v.26 no.4
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• pp.217-224
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• 2014

Cochlodinium polykrikoides is a typical harmful algal species which generates the red-tide in the coastal zone, southern Korea. Accurate algal growth model can be established and then the prediction of the red-tide occurrence using this model is possible if the information on the optimal growth model parameters are available because it is directly related between the red-tide occurrence and the rapid algal bloom. However, the limitation factors on the algal growth, such as light intensity, water temperature, salinity, and nutrient concentrations, are so diverse and also the limitation function types are diverse. Thus, the study on the algal growth model development using the available laboratory data set on the growth rate change due to the limitation factors are relatively very poor in the perspective of the model. In this study, the growth model on the C. polykrikoides are developed and suggested as the optimal model which can be used as the element model in the red-tide or ecological models. The optimal parameter estimation and an error analysis are carried out using the available previous research results and data sets. This model can be used for the difference analysis between the lab. condition and in-situ state because it is an optimal model for the lab. condition. The parameter values and ranges also can be used for the model calibration and validation using the in-situ monitoring environmental and algal bloom data sets.

• Journal of the korean academy of Pediatric Dentistry
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• v.32 no.2
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• pp.256-261
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• 2005

Scleroderma is a connective tissue disease of unknown etiology, but known as a kind of auto-immune disease. It is most common in women especially in $30{\sim}50$ years, and very rare in childhood. It can be classified into two main classes : localized scleroderma & systemic sclerosis. Localized type has better prognosis, and usually involves skin only, or in some cases, the muscle below, except inner organs. Systemic type involves skin, oral mucosa and major internal organs. Involving facial skin, we can see small and sharp nose, expressionless stare and narrow oral aperture. Usually they have Raynaud's phenomenon, and in progress, show mouth opening limitation and sclerosis of tongue and gingiva. It is called CREST syndrome showing calcinosis cutis, Raynaud's phenomenon, esophageal dysfunction, sclerodactyly, and telangioectasia. Treatment of scleroderma is systemic and localized steroid therapy, use of collagen-link inhibitor (D-penicillamine), immune depressor and etc. Mouth opening limitation can be improved by mouth stretching exercise. We report a 6 years old boy, diagnosed with localized scleroderma who had mouth opening limitation. We could get additional mouth opening, and have done successful restorative treatment of mandibular and maxillary 1st and 2nd deciduous molar under deep sedation with nitrous oxide and enflurane.

• Journal of KIISE:Information Networking
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• v.28 no.2
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• pp.251-261
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• 2001

The traffic on the Internet has been growing exponentially for some time. This growth is beginning to stress the current-day routers. However, switching technology offers much higher performance. So the label switching network which combines IP routing with switching technology, is emerged. EspeciaJJy in the data driven label switching, flow classification and cache table management are needed. Flow classification is to classify packets into switching and non-switching packets, and cache table management is to maintain the cache table which contains information for flow classification and label switching. However, the cache table management affects the performance of label switching network considerably as well as flowclassification because the bigger cache table makes more packet switched and maintains setup cost lower, but cache is restricted by local router resources. For that reason, there is need to study the cache replacement scheme for the efficient cache table management with the Internet traffic characterized by user. So in this paper, we propose several cache replacement schemes for label switching network. First, without the limitation at switching capacity in the router. we introduce FIFO(First In First Out). LFC(Least Flow Count), LRU(Least Recently Used! scheme and propose priority LRU, weighted priority LRU scheme. Second, with the limitation at switching capacity in the router, we introduce LFC-LFC, LFC-LRU, LRU-LFC, LRU-LRU scheme and propose LRU-weighted LRU scheme. Without limitation, weighted priority LRU scheme and with limitation, LRU-weighted LRU scheme showed best performance in this paper.

• Journal of Biomedical Engineering Research
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• v.21 no.4
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• pp.391-401
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• 2000

Flow through compliant tubes with linear taper in wall thickness is numerically simulated by finite element analysis. For verification of the numerical method, flow through a compliant stenotic vessel is simulated and the results are compared to the existing experimental data. Steady two-dimensional flow in a collapsible channel with initial tension is also simulated and the results are compared with numerical solutions from the literature. Computational results show that as cross-sectional area decreases with the reduction in downstream pressure, flow rate increases and reaches the maximum when the speed index (mean velocity divided by wave speed) is near the unity at the point of minimum cross-section area, indicating the flow limitation or choking (flow speed equals wave speed) in one-dimensional studies. for further reductions in downstream pressure, flow rate decreases. The flow limitation or choking consist of the main reasons of waterfall effect which occurs in the airways, capillaries of lung, and other veins. Cross-sectional narrowing is significant but localized. When the ratio of downstream-to-upstream wall thickness is 2, the area throat is located near the downstream end. As this ratio is increased to 3, the constriction moves to the upstream end of the tube.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.15 no.5
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• pp.3345-3350
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• 2014

We investigated to assess the relationships between the major nutrients and phytoplankton dynamics during the spring season in 2010 and 2011 at 23 stations in Jinhae Bay, Korea. The bay is divided into four different zones based on pollutant sources and geographical characteristics. Nutrient limitation (>80%) was significant in Zone II, which is located in central bay and is influenced by the water well mixed from outer bay. The limited nutrient was followed in Zone III and IV that was occupying between 17% and 83%. However, the low levels are being kept below 35% in Zone I, which is characterized by the semi-enclosed eutrophic area of Masan and Haegam bays. Based on the PCA (principle component analysis) analysis, the nitrogen (N) sources in 2010 were particularly dominant and it may be due to the water mixing and wastewater formed from bottom layers and sewage. In 2011, major nutrients including nitrogen, silicon and phosphorus were dominant in the bay and are supplied by the river discharge after rainfalls with low salinity conditions. In particular, the N nutrients being supplied in 2010 are correlated with pennate diatoms Pseudo-nitzchia spp. and is not related to the phytoplankton population densities in 2011. The present study suggests that N sources play an important role in the proliferation of diatom, and the rapid nutrient uptakes by them are potential nutrient limitation factors in the bay.

• The Korean Journal of Nuclear Medicine Technology
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• v.22 no.1
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• pp.55-66
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• 2018

Purpose In PET/CT exam, washed-out artifact could occur due to severe motion of the patient and high specific activity, it results in lowering not only qualitative reading but also quantitative analysis. Scatter limitation correction by GE is an algorism to correct washed-out artifact and recover the images in PET scan. The purpose of this study is to measure the threshold of specific activity which can recovers to original uptake values on the image shown with washed-out artifact from phantom experiment and to compare the quantitative analysis of the clinical patient's data before and after correction. Materials and Methods PET and CT images were acquired in having no misalignment(D0) and in 1, 2, 3, 4 cm distance of misalignment(D1, D2, D3, D4) respectively, with 20 steps of each specific activity from 20 to 20,000 kBq/ml on $^{68}Ge$ cylinder phantom. Also, we measured the distance of misalignment of foley catheter line between CT and PET images, the specific activity which makes washed-out artifact, $SUV_{mean}$ of muscle in artifact slice and $SUV_{max}$ of lesion in artifact slice and $SUV_{max}$ of the other lesion out of artifact slice before and after correction respectively from 34 patients who underwent $^{18}F-FDG$ Fusion Whole Body PET/CT exam. SPSS 21 was used to analyze the difference in the SUV between before and after scatter limitation correction by paired t-test. Results In phantom experiment, $SUV_{mean}$ of $^{68}Ge$ cylinder decreased as specific activity of $^{18}F$ increased. $SUV_{mean}$ more and more decreased as the distance of misalignment between CT and PET more increased. On the other hand, the effect of correction increased as the distance more increased. From phantom experiments, there was no washed-out artifact below 50 kBq/ml and $SUV_{mean}$ was same from origin. On D0 and D1, $SUV_{mean}$ recovered to origin(0.95) below 120 kBq/ml when applying scatter limitation correction. On D2 and D3, $SUV_{mean}$ recovered to origin below 100 kBq/ml. On D4, $SUV_{mean}$ recovered to origin below 80 kBq/ml. From 34 clinical patient's data, the average distance of misalignment was 2.02 cm and the average specific activity which makes washed-out artifact was 490.15 kBq/ml. The average $SUV_{mean}$ of muscles and the average $SUV_{max}$ of lesions in artifact slice before and after the correction show a significant difference according to a paired t-test respectively(t=-13.805, p=0.000)(t=-2.851, p=0.012), but the average $SUV_{max}$ of lesions out of artifact slice show a no significant difference (t=-1.173, p=0.250). Conclusion Scatter limitation correction algorism by GE PET/CT scanner helps to correct washed-out artifact from motion of a patient or high specific activity and to recover the PET images. When we read the image occurred with washed-out artifact by measuring the distance of misalignment between CT and PET image, specific activity after applying scatter limitation algorism, we can analyze the images more accurately without repeating scan.