• Title/Summary/Keyword: light sensitivity

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A Delphi Survey on Performance Indicators of Korean Advanced Practice Nurses (전문간호사 성과지표에 관한 델파이 조사)

  • Kim, Keum Soon;Kang, Ji Yeon;Kim, Bok Ja;Lee, Young Hee;Lee, Eun Nam
    • Journal of Korean Clinical Nursing Research
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    • v.16 no.1
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    • pp.131-143
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    • 2010
  • Purpose: The purpose of this survey was to identify a set of performance indicators for Korean APNs (Advanced Practice Nurses). Methods: A convenience sample of 78 APNs working in 2 leading hospitals in south Korea participated in the three-round Delphi survey. In the first round, subjects were asked to propose performance indicators to evaluate the effectiveness of their practice. They rated the relevancy of each indicator during the second round. In the final round of survey, subjects rated the relevancy of indicators again in the light of second round's overall results and they also were asked to check on current and future use of indicators. Results: After 5 months of three-round Delphi survey, 60 performance indicators were identified. In regard to relevancy, the 10 highly ranked indicators were patient satisfaction, self-care ability, expertise of service, family satisfaction, nurse satisfaction, satisfaction in nursing education, advanced nursing service count, education for patient/ family, education for nurse, and compliance. Advanced nursing service count, education for patient/ family, and education for nurse are currently used as indicators by more than 70% of respondents. Conclusion: Additional research is needed to identify subsets of performance indicators for specialized areas and to determine the validity and sensitivity of indicators.

Electrochemical Detection of Hydroxychloroquine Sulphate Drug using CuO/GO Nanocomposite Modified Carbon Paste Electrode and its Photocatalytic Degradation

  • G. S. Shaila;Dinesh Patil;Naeemakhtar Momin;J. Manjanna
    • Journal of the Korean Electrochemical Society
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    • v.27 no.1
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    • pp.15-31
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    • 2024
  • The antimalarial drug hydroxychloroquine sulphate (HCQ) has taken much attention during the first COVID-19 pandemic phase for the treatment of severe acute respiratory infection (SARI) patients. Hence it is interest to study the electrochemical properties and photocatalytic degradation of the HCQ drug. Copper oxide (CuO) nanoparticles, graphene oxide (GO) and CuO/GO NC (nanocomposite) modified carbon paste electrodes (MCPE) are used for the detection of HCQ in an aqueous medium. Electrochemical behaviour of HCQ (20 μM) was observed using CuO/MCPE, GO/MCPE and CuO/GO NC/MCPE in 0.1 M phosphate buffer at pH 7 with a scan rate of 20 to 120 mV s-1 by cyclic voltammetry (CV). Differential pulse voltammetry (DPV) of HCQ was performed for 0.6 to 16 μM HCQ. The CuO/GO NC/MCPE showed a reasonably good sensitivity of 0.33 to 0.44 μA μM cm-2 with LOD of 69 to 92 nM for HCQ. Furthermore, the CuO/GO NC was used as a catalyst for the photodegradation of HCQ by monitoring its UV-Vis absorption spectra. About 98% was degraded in about 34 min under visible light and after 4 cycles it was 87%. The improved photocatalytic activity may be attributed to decrease in bandgap energy and enhanced ability for the electrons to migrate. Thus, CuO/GO NC showed good results for both sensing and degradation applications as well as reproducibility.

Long-term shape sensing of bridge girders using automated ROI extraction of LiDAR point clouds

  • Ganesh Kolappan Geetha;Sahyeon Lee;Junhwa Lee;Sung-Han Sim
    • Smart Structures and Systems
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    • v.33 no.6
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    • pp.399-414
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    • 2024
  • This study discusses the long-term deformation monitoring and shape sensing of bridge girder surfaces with an automated extraction scheme for point clouds in the Region Of Interest (ROI), invariant to the position of a Light Detection And Ranging system (LiDAR). Advanced smart construction necessitates continuous monitoring of the deformation and shape of bridge girders during the construction phase. An automated scheme is proposed for reconstructing geometric model of ROI in the presence of noisy non-stationary background. The proposed scheme involves (i) denoising irrelevant background point clouds using dimensions from the design model, (ii) extracting the outer boundaries of the bridge girder by transforming and processing the point cloud data in a two-dimensional image space, (iii) extracting topology of pre-defined targets using the modified Otsu method, (iv) registering the point clouds to a common reference frame or design coordinate using extracted predefined targets placed outside ROI, and (v) defining the bounding box in the point clouds using corresponding dimensional information of the bridge girder and abutments from the design model. The surface-fitted reconstructed geometric model in the ROI is superposed consistently over a long period to monitor bridge shape and derive deflection during the construction phase, which is highly correlated. The proposed scheme of combining 2D-3D with the design model overcomes the sensitivity of 3D point cloud registration to initial match, which often leads to a local extremum.

Photosynthesis and Formation of UV-absorbing Substances in Antarctic Macroalgae Under Different Levels of UV-B Radiation (중파자외선에 대한 남극산 해조류의 광합성 및 자외선 흡수물질 형성 반응)

  • 한태준;박병직;한영석;강성호;이상훈
    • Korean Journal of Environmental Biology
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    • v.20 no.3
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    • pp.205-215
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    • 2002
  • Effects of artificial and solar W-B radiation on five rhodophytes (Curdiea racovitzae, Gigaytina skottsbergii, Mazzaella obovata, Myriogramme manginii, Palmaria decipiens) from Antarctica have been investigated using PAM fluorescence in laboratory and in the field. Laboratory studies showed that there were significant differences in the UV sensitivity between different species, and that the differences appeared to be correlated with the depth of collection of the specimens. It was apparent from the observations that the samples such as M. manginii and P. decipiens collected from 20-30 m depths were move sensitive to W-B radiation compared with those collected from shallower depths, The present study confirmed that an acclimation to the surrounding light regime could be an important factor to determine the UV-sensitivity of a species or individuals and that PAM measurements are rapid and non-destructive methods to evaluate UV influences. From field studies on M. manginii and P. decipiens it was observed that both plants exhibited changes in the effective quantum yield, with the minimum values nt noon followed by n recovery in the evening. Photoinhibition occurred in these species could therefore be accounted for by so- called dynamic photoinhibition. It seems likely that this protective mechanism may contribute to survival of the species in shallow water where they may encounter intense solar radiation. The presence or absence of the W- B component under solar radiation differently affected the photosynthetic recovery process, and the rate of recovery was much stoney in UV- present than in W- absent conditions. Functional role of W- B appears to delay the recovery of photosynthesis in the studied macroalgae. Differential sensitivity to UV-B recognised between M. manginii and P. decipiens seemed to correspond well with the amount of UV-absorbing substances (UVAS) contained in the respective species. Higher tolerance to solar radiation by the latter species may be due to the higher amount of UVAS. There were variations of UVAS concentrations in algal thalli depending on the season and depth of collection.

Investigation of O4 Air Mass Factor Sensitivity to Aerosol Peak Height Using UV-VIS Hyperspectral Synthetic Radiance in Various Measurement Conditions (UV-VIS 초분광 위성센서 모의복사휘도를 활용한 다양한 관측환경에서의 에어로솔 유효고도에 대한 O4 대기질량인자 민감도 조사)

  • Choi, Wonei;Lee, Hanlim;Choi, Chuluong;Lee, Yangwon;Noh, Youngmin
    • Korean Journal of Remote Sensing
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    • v.36 no.2_1
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    • pp.155-165
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    • 2020
  • In this present study, the sensitivity of O4 Air Mass Factor (AMF) to Aerosol Peak Height (APH) has been investigated using radiative transfer model according to various parameters(wavelength (340 nm and 477 nm), aerosol type (smoke, dust, sulfate), aerosol optical depth (AOD), surface reflectance, solar zenith angle, and viewing zenith angle). In general, it was found that O4 AMF at 477 nm is more sensitive to APH than that at 340 nm and is stably retrieved with low spectral fitting error in Differential Optical Absorption Spectroscopy (DOAS) analysis. In high AOD condition, sensitivity of O4 AMF on APH tends to increase. O4 AMF at 340 nm decreased with increasing solar zenith angle. This dependency isthought to be induced by the decrease in length of the light path where O4 absorption occurs due to the shielding effect caused by Rayleigh and Mie scattering at high solar zenith angles above 40°. At 477 nm, as the solar zenith angle increased, multiple scattering caused by Rayleigh and Mie scattering partly leads to the increase of O4 AMF in nonlinear function. Based on synthetic radiance, APHs have been retrieved using O4 AMF. Additionally, the effect of AOD uncertainty on APH retrieval error has been investigated. Among three aerosol types, APH retrieval for sulfate type is found to have the largest APH retrieval error due to uncertainty of AOD. In the case of dust aerosol, it was found that the influence of AOD uncertainty is negligible. It indicates that aerosol types affect APH retrieval error since absorption scattering characteristics of each aerosol type are various.

DETECTION OF EARLY PROXIMAL CARIES WITH LASER FLUORESCENCE (레이저 형광법을 이용한 인접면 우식증의 진단)

  • Seol, Jae-Heon;Oh, You-Hyang;Lee, Nan-Young;Lee, Sang-Ho
    • Journal of the korean academy of Pediatric Dentistry
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    • v.31 no.2
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    • pp.236-246
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    • 2004
  • Artificial carious lesions in various depths were observed with visual examination using light transillumination, bite-wing radiography, laser fluorescence, and dye-enhanced laser fluorescence to determine the reproducibility, correlation of each diagnostic method, diagnostic sensitivity and diagnostic specificity. And optical densities according to demineralized times were measured whether laser fluorescence could be used as a quantitative diagnostic method. The following results were obtained whether laser fluorescence could be used for diagnosis of initial proximal caries. 1. Tau-c values of visual examination was 0.08 which showed lowest reproducibility and those of bite-wing radiography, laser fluorescence, dye-enhanced laser fluorescence were 0.60, 0.48, and 0.64, respectively which showed relatively high reproducibility. 2. The correlation between demineralization time and each examination was the highest in dye-enhanced laser fluorescence$({\gamma}=0.51)$ followed by laser fluorescence$({\gamma}=0.43)$, bite-wing radiograph$({\gamma}=0.35)$, and visual examination$({\gamma}=0.33)$. Dye-enhanced laser fluorescence and laser fluorescence showed significant correlation with demineralization time. 3. The sensitivity of laser fluorescence and dye-enhanced laser fluorescence for diagnosing approximal caries based on bite-wing radiography were 67%, 100% and those of specificity were 57%, 11% which showed diagnostic specificity was relatively lower than sensitivity. 4. The difference in optical density(DFR) between sound teeth and carious lesions according to lesion depth was high with dye-enhanced laser fluorescence compared with laser fluorescence. DFR measured with laser fluorescence according to changes in lesion depth was statistically significant but was not statistically significant with dye-enhanced laser fluorescence. Based on these results, laser fluorescence and dye-enhanced laser fluorescence have comparable diagnostic power as bite-wing radiography in early diagnosis of proximal caries.

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Feasibility Study of the Real-Time IMRT Dosimetry Using a Scintillation Screen (고감도 형광판을 이용한 실시간 선량측정 가능성 연구)

  • Lim Sang Wook;Yi Byong Yong;Ko Young Eun;Ji Young Hoon;Kim Jong Hoon;Ahn Seung Do;Lee Sang Wook;Shin Seong Soo;Kwon Soo-Il;Choi Eun Kyoung
    • Radiation Oncology Journal
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    • v.22 no.1
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    • pp.64-68
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    • 2004
  • Purpose : To study the feasibility of verifying real-time 2-D dose distribution measurement system with the scintillation screen for the quality assurance. Materials and Methods : The water phantom consisted of a scintillation screen (LANEX fast screen, Kodak, USA) that was axially located in the middle of an acrylic cylinder with a diameter of 25 cm. The charge-coupled device (CCD) camera was attached to the phantom In order to capture the visible light from the scintillation screen. To observe the dose distribution In real time, the intensity of the light from the scintillator was converted to a dosage. The isodose contours of the calculations from RTP and those of the measurements using the scintillation screen were compared for the arc therapy and the Intensity modulated radiation therapy (IMRT). Results : The kernel, expressed as a multiplication of two error functions, was obtained in order to correct the sensitivity of the CCD of the camera and the scintillation screen. When comparing the calculated isodose and measured isodose, a discrepancy of less than 8 mm in the high dose region was observed. Conclusion : Using the 2-D dosimetry system, the relationship between the light and the dosage could be found, and real-time verification of the dose distribution was feasible.

Monitoring of Mythimna separata Adults by Using a Remote-sensing Sex Pheromone Trap (원격감지 성페로몬트랩을 이용한 멸강나방(Mythimna separata) 성충 예찰)

  • Jung, Jin Kyo;Seo, Bo Yoon;Cho, Jum Rae;Kim, Yong
    • Korean journal of applied entomology
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    • v.52 no.4
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    • pp.341-348
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    • 2013
  • We desinged and evaluated a remote-sensing sex pheromone trap for real-time monitoring of Mythimna separata (Lepidoptera: Noctuidae), a migratory insect in Korea. The system consisted of a modified cone-trap with a sex pheromone lure, a sensing module based on light interruption, a signal transmission module based on code division multiple access, a main electronic board for system control, a power supply based on a solar collector, a stainless steel-pole supporting the system, and a signal collection and display system based on an internet web page. The ratio (>92%) of the actual number of insects to the signal number in the remote-sensing trap was improved by sensing only within a limited period at night on the basis of the insect's circadian rhythm, control of signal sensitivity on the basis of sensing software programming, 1-h interval for signal transmission, and adjustment of the signal transmission program. The signal occurrence pattern in the remote-sensing trap was conclusively similar (correlation coefficient, >0.98) to the actual pattern of adult occurrence in the trap. The result indicated that the remote-sensing trap based on the attraction of the sex pheromone lure for M. separata has a promising potential for practical use. Occurrence of M. separata adults was observed several times in 2011 and 2012, and the peaks were sharp.

Outlier Detection from High Sensitive Geiger Mode Imaging LIDAR Data retaining a High Outlier Ratio (높은 이상점 비율을 갖는 고감도 가이거모드 영상 라이다 데이터로부터 이상점 검출)

  • Kim, Seongjoon;Lee, Impyeong;Lee, Youngcheol;Jo, Minsik
    • Korean Journal of Remote Sensing
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    • v.28 no.5
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    • pp.573-586
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    • 2012
  • Point clouds acquired by a LIDAR(Light Detection And Ranging, also LADAR) system often contain erroneous points called outliers seeming not to be on physical surfaces, which should be carefully detected and eliminated before further processing for applications. Particularly in case of LIDAR systems employing with a Gieger-mode array detector (GmFPA) of high sensitivity, the outlier ratio is significantly high, which makes existing algorithms often fail to detect the outliers from such a data set. In this paper, we propose a method to discriminate outliers from a point cloud with high outlier ratio acquired by a GmFPA LIDAR system. The underlying assumption of this method is that a meaningful targe surface occupy at least two adjacent pixels and the ranges from these pixels are similar. We applied the proposed method to simulated LIDAR data of different point density and outlier ratio and analyzed the performance according to different thresholds and data properties. Consequently, we found that the outlier detection probabilities are about 99% in most cases. We also confirmed that the proposed method is robust to data properties and less sensitive to the thresholds. The method will be effectively utilized for on-line realtime processing and post-processing of GmFPA LIDAR data.

Phototoxicity Evaluation of Pharmaceutical Substances with a Reactive Oxygen Species Assay Using Ultraviolet A

  • Lee, Yong Sun;Yi, Jung-Sun;Lim, Hye Rim;Kim, Tae Sung;Ahn, Il Young;Ko, Kyungyuk;Kim, JooHwan;Park, Hye-Kyung;Sohn, Soo Jung;Lee, Jong Kwon
    • Toxicological Research
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    • v.33 no.1
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    • pp.43-48
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    • 2017
  • With ultraviolet and visible light exposure, some pharmaceutical substances applied systemically or topically may cause phototoxic skin irritation. The major factor in phototoxicity is the generation of reactive oxygen species (ROS) such as singlet oxygen and superoxide anion that cause oxidative damage to DNA, lipids and proteins. Thus, measuring the generation of ROS can predict the phototoxic potential of a given substance indirectly. For this reason, a standard ROS assay (ROS assay) was developed and validated and provides an alternative method for phototoxicity evaluation. However, negative substances are over-predicted by the assay. Except for ultraviolet A (UVA), other UV ranges are not a major factor in causing phototoxicity and may lead to incorrect labeling of some non-phototoxic substances as being phototoxic in the ROS assay when using a solar simulator. A UVA stimulator is also widely used to evaluate phototoxicity in various test substances. Consequently, we identified the applicability of a UVA simulator to the ROS assay for photoreactivity. In this study, we tested 60 pharmaceutical substances including 50 phototoxins and 10 non-phototoxins to predict their phototoxic potential via the ROS assay with a UVA simulator. Following the ROS protocol, all test substances were dissolved in dimethyl sulfoxide or sodium phosphate buffer. The final concentration of the test solutions in the reaction mixture was 20 to $200{\mu}M$. The exposure was with $2.0{\sim}2.2mW/cm^2$ irradiance and optimization for a relevant dose of UVA was performed. The generation of ROS was compared before and after UVA exposure and was measured by a microplate spectrophotometer. Sensitivity and specificity values were 85.7% and 100.0% respectively, and the accuracy was 88.1%. From this analysis, the ROS assay with a UVA simulator is suitable for testing the photoreactivity and estimating the phototoxic potential of various test pharmaceutical substances.