• 한국임상약학회지
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• 제2권1호
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• pp.29-39
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• 1992

In a survey of drug abuse of fourteen types of drugs by employees of public house, the results are follows. $87.4\%$ of male and $82.1\%$ of female ever smoked in his/her life time. $82.2\%$ of male and $75.2\%$ of female smoked in the past month. $90.4\%$ of male and $93.9\%$ of female ever drank in his/her life time. $82.2\%$ of male and $81.6\%$ of female in the past month. $57.8\%$ of male and $54.9\%$ of female smoked daily and $27.4\%$ of male and $53.6\%$ of female drank daily. $3.9\%$ of the employees of public house ever used marijuana in his/her life time: $1.7\%$, stimulants : $5.6\%$ inhalants : $10.0\%$ tranquilizers: $14.6\%$, hypnotics : $32.9\%$ analgesics: $3.7\%$, antitussives: and $1.4\%$, antihistamines; $1.5\%$, cocaine; $0.0\%$ amphetamines; $0.6\%$ narcotics: and $4.71\%$, hallucinogens. Drug use and delinquency showed a dosed relationship: drug users committed higher degree of delinquent behaviors and delinquents used drugs more frequently.

• 한국품질경영학회:학술대회논문집
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• 한국품질경영학회 2010년도 춘계학술대회
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• pp.262-268
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• 2010

Organic light emitting diode is developed fast from 1963 after discovering electric light emitting phenomenon. First PMOLED(passive matrix OLED) product is manufactured and AMOLED(active matrix OLED) using TFT(thin film ransistor) is now in the center. PMOLED is mainly mounted at sub display. but AMOLED is mounted at main display. Also AMOLED expand the market to PMP(portable multimedia players), navigation and TV. Even thought OLED's market is opening to many applications, OLED is worried about lifetime until now. That's appeared in market in a very short time and is not known well about result of OLED's lifetime and reliability test. And there is no standard ssessment method and not enough study to standardization the method. A study's purpose is reduce the time for life test by accelerated current and it can do production possible design by accelerated life model in design phase. It's must be add to process variables and design variables(like ratio of light emitting, organic material structure, condition of aging, etc) to make the best use of supplied accelerated lifetime model in this paper. In terms of lifetime it needs each criterion of applications because of image sticking. In conclusion, it's possible to discover new defect because there is not much time to be opened in market and develop a method of manufacturing process & materials, so we need to study on the subject of this paper continuously.

• Journal of the Korean Wood Science and Technology
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• 제48권4호
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• pp.548-561
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• 2020

Paecilomyces japonica is widely cultured to produce mycelium for medicinal and health food use. Illumination is an important factor in the growth and production of mycelium in submerged culture. The effects of different light-emitting diode (LED) combinations on the growth and cordycepin content as bioactive substances of mycelium were investigated. The results showed that the mycelium dry weights were lower under dark condition and red LED treatments. Dark condition, fluorescent light, and ultraviolet-A failed to increase the cordycepin content. Blue light was necessary to increase the cordycepin content, and a red-to-blue ratio of 3:7 induced the highest cordycepin content. The cordycepin contents of mycelium in submerged culture were significantly higher in a 12 h/day illumination time under red and blue (red-to-blue ratio of 3:7) LED treatments, showing an increase of up to 38% compared with those under the fluorescent-light control condition. The results demonstrated the roles of light with different wavelengths on the biosynthesis of cordycepin as bioactive substances. The low-heat release and replacement of traditional fluorescent lights with low-energy-consuming LEDs could increase the contents of bioactive substances. After optimization of the cordycepin production using response surface methodology (Box-Behnken design) to its canonical form, the optimum combination was found to be as follows: illumination time = 17.7 h/day, sugar content in the medium = 9.7 g/50 mL, and incubation time = 61.2 h. The model predicted a maximum response of 3779.2 ㎍/mL cordycepin yield.

• 감성과학
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• 제26권4호
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• pp.15-28
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• 2023

행복은 개인들이 추구하는 삶의 가장 중요한 목적이라고 할 수 있다. 본 연구에서는 행복 증진을 위해서 개인들이 스스로 자신의 웰니스를 점검하고 관리하는 것이 필요하다고 보고, 셀프 라이프코칭 앱의 웰니스 증진 효과에 대한 예비 연구를 진행하였다. 이를 위해, 총 36명의 참여자를 실험집단(1·2)과 통제집단에 무선배정하고, 실험집단에는 연구용 앱을 활용해 4주간 셀프 라이프코칭을 수행하도록 하였다. 실험처치 중 주간 피드백을 실험집단1에는 제공하고, 실험집단2에는 제공하지 않았다. 종속변인으로 노동자를 위한 웰니스 지수(WIW)와 한국형 웰니스 척도(KWS)를 사용하였다. 실험결과, 사전, 사후, 추후의 시점과 집단 간의 상호작용 효과는 통계적으로 유의미하지 않았으나, 효과의 경향성을 확인하였다. 주간 피드백 유무에 따른 실험처치 효과 차이는 확인되지 않았다. 시간에 따른 웰니스 증진 효과가 통계적으로 유의미했으며, 실험처치가 웰니스에 미치는 효과가 선형적임을 확인하였다. 참여의견 조사 결과, 참여자의 84.2%가 이번 활동이 도움이 된다고 하였으며, 78.9%가 상용화된 앱이 있다면 1주 또는 2주에 한번 사용하겠다고 응답하였다. 본 연구는 누구나 스스로 자신의 웰니스 증진에 활용할 수 있는 방법론을 제시하였으며, 그 효과를 일정 부분 확인하였다는 점에서 의의가 있다.

• 산업진흥연구
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• 제8권2호
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• pp.119-132
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• 2023

본 논문의 목적은 명리학과 기문둔갑에서 사용하는 사주(四柱)라는 동양의 시간 개념을 재정립하고 특히 시주(時柱)에 대한 정확성과 객관화를 위해 출생 지역에 따른 진태양시의 사용, 야자시(夜子時)와 정자시(正子時) 중 정자시의 선택, 태시(胎時)에 대한 정확한 의미 확인 등을 논의하고자 함이다. 한국 사회에서 통념적 시간의 사용은 동경시를 표준시로 삼고, 자정 0시를 기준으로 새로운 날이 시작되는 시진을 사용한다. 하지만 역학적으로 중요한 것은 사회적 통용성이 아니라 우주의 중심인 내가 태어난 그 우주의 시간과 공간이 내 명(命)의 기준이 되어야 하므로 내가 태어난 장소의 경도를 사용하여 정확한 나의 시진(時辰)을 결정해야만 하고, 우주 에너지의 흐름은 반 시진, 즉 1시간은 앞서 '기미와 징조'가 발생하므로 역술과 명리학에서 오랜 기간 논쟁의 화두가 되어왔던 간지기시법 중 야자시와 정자시의 선택 문제는 정자시법을 적용해야 한다고 주장한다. 이러한 시진과 시주의 설정에 대한 타당성을 확보하기 위해 기문둔갑의 포국을 통한 시진 조정법을 활용하여 사례 분석을 시행하였다. 분석 대상자와의 심층 면담을 통해 과거 살아온 인생을 날짜와 시간별로 수집한 후 각 인생 사건의 발생 시기가 정확한지를 기문둔갑 해단법으로 확인해 보았다.

• 품질경영학회지
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• 제39권1호
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• pp.71-77
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• 2011

In the fields of reliability application, the most commonly used test methods for reliability qualification are zero failure tests since they require fewer test samples and less test time compared to other test methods that guarantee the same reliability with a given confidence level. An economic zero failure test plan is developed that minimizes the total cost related to perform a life test to guarantee a specified reliability of a product with a given confidence level and a numerical example is provided to illustrate the use of the proposed test method.

• Architectural research
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• 제7권2호
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• pp.81-89
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• 2005

Over the years, existing bridges have had various degrees of maintenance to extend the service life. As the existing bridges continue to deteriorate, however, each Department of Transportation (DOT) of the United States of America faces increasing demands on the limited funds available for bridge maintenance. Therefore, it is very important for State Department of Transportations to establish Maintenance, Repair, and Rehabilitation (MR&R) strategies for bridge structures such that funds get allocated for appropriate maintenance over the service life. This paper identifies the state-of-art and the state-of-practice of MR&R actions and the use of MR&R strategies in concrete bridge decks. In addition, a questionnaire survey was conducted to identify the type and timing for MR&R actions as well as existing MR&R strategies taken in concrete bridge deck by each DOT. This paper also presents the results of the survey.

• Journal of the Korean Data and Information Science Society
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• 제13권2호
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• pp.87-95
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• 2002

In this paper we consider optimal designs of partially accelerated life testing which is devised for multi-component mixed systems with the considerably long lifetime. Test items are run at both use condition and accelerated condition until a specified censoring time. The optimal criterion for the sample-proportion allocated to accelerated condition is to minimize asymptotic variance of the maximum likelihood estimators of the acceleration factor and hazard rates.

• Biomolecules & Therapeutics
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• 제18권4호
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• pp.375-385
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• 2010

Conventional cancer chemotherapy is seriously limited by tumor cells exhibiting multidrug resistance (MDR), which is caused by changes in the levels or activity of membrane transporters that mediate energy-dependent drug efflux and of proteins that affect drug metabolism and/or drug action. Cancer scientists and oncologists have worked together for some time to understand anticancer drug resistance and develop pharmacological strategies to overcome such resistance. Much focus has been on the reversal of the MDR phenotype by inhibition of ATP-binding cassette (ABC) drug transporters. ABC transporters are a family of transporter proteins that mediate drug resistance and low drug bioavailability by pumping various drugs out of cells at the expense of ATP hydrolysis. Many inhibitors of MDR transporters have been identified, and though some are currently undergoing clinical trials, none are in clinical use. Herein, we briefly review the status of MDR in human cancer, explore the pathways of MDR in chemotherapy, and outline recent advances in the design and development of MDR modulators.

• 한국응용과학기술학회지
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• 제27권2호
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• pp.196-201
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• 2010

The influence of red lead($Pb_3O_4$) to curing and formation reaction properties when it was added in positive material of lead acid battery for vehicle use has been investigated. At the results, it was confirmed that the addition of red lead led 4BS crystal size to be smaller and increased the rates of 4BS formation and Pb consumption. Consequently the curing time was shortened to half compared with that of red lead-free one. In addition to this, the lead acid battery prepared by adding red lead showed 14% higher efficiency at the life cycle test than that without red lead.