• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.6
• /
• pp.2403-2407
• /
• 2015

Background: Very few analytical studies are available on any association between stressful life events (SLE) and colorectal cancer (CRC), at least in Iran. The aim of this case control study was to determine the association between stressful life events (SLE) and colorectal cancer. Materials and Methods: This study was conducted in four hospital colonoscopy units in Tabriz city of Iran including 414 participants aged 40-75 years: 207 cases with CRC confirmed by pathology and colonoscopy findings and 207 controls free of neoplastic conditions were selected (from the same hospitals at the same period for the cases and after matching for age and sex). Stressful life events were assessed using a 43-item Holmes and Rahe Life Events Questionnaire. Multivariate logistic regression was used to estimate adjusted odds ratios for SLE and risk of CRC. Results: The stressful life event mean score in the case group was 141.3, in contrast to 63.8 in the control group (p<0.011). After adjusting for confounders, death of dear ones increased the risk of CRC (OR: 2.49; 95%CI: 1.41-5.13). Other types of stressful life events (family and husband disputes, serious occupational problems, unemployment of > 6 months, and Serious financial problems) were also associated with CRC, but without statistical significance. Conclusions: According to our findings, it seems that SLE may increase the risk of CRC.

• Journal of Korean society of Dental Hygiene
• /
• v.10 no.6
• /
• pp.1015-1024
• /
• 2010

Objectives : This study was to investigate the level of health risk behavior, athletes stress, quality of life(WHOQOL-BREF) and oral health related quality of life(OHIP-14) and the clinical factors influencing quality of life in athletes Methods : Data were obtained from a cross-sectional survey of 202 university athletes. Data was obtained by means of questionnaire from October 11 to October 15, 2010. Health risk behaviors(Q-F index and smoking), athletes stress, WHOQOL-BREF and OHIP-14 were measured. The data was analysed with t-test, one-way ANOVA, Pearson correlation coefficient and multiple regression using the SPSS program. Results : The prevalence of alcohol drinking, smoking were 84.2% and 37.9%, respectively. Alcohol drinking and cigarette consumption were not related to quality of life though there were the negative correlation between athletes stress and quality of life. Powerful predictors of quality of life were athletes stress, OHIP-14 and perceived health for athletes. Conclusions : Based on the findings, quality of life has a significantly impact on athletes stress, OHIP-14 and perceived health. These results suggest that the implementation of health promotion program should be considered which was decreased athletes stress and was increased level of oral health and perceived health in athletes.

• Journal of Environmental Impact Assessment
• /
• v.9 no.3
• /
• pp.203-214
• /
• 2000

Health risk assessment is applied to streamlining LCA(Life Cycle Assessment) using Monte carlo simulation for probabilistic/stochastic exposure and risk distribution analysis caused by data variability and uncertainty. A case study was carried out to find benefits of this application. BTC(Benzene, Trichloroethylene, Carbon tetrachloride mixture alias) personal exposure cases were assumed as production worker(in workplace), manager(in office) and business man(outdoor). These cases were different from occupational retention time and exposure concentration for BTC consumption pattern. The result of cancer risk in these 3 scenario cases were estimated as $1.72E-4{\pm}1.2E+0$(production worker; case A), $9.62E-5{\pm}1.44E-5$(manger; case B), $6.90E-5{\pm}1.16E+0$(business man; case C), respectively. Portions of over acceptable risk 1.00E-4(assumed standard) were 99.85%, 38.89% and 0.61%, respectively. Estimated BTC risk was log-normal pattern, but some of distributions did not have any formal patterns. Except first impact factor(BTC emission quantity), sensitivity analysis showed that main effective factor was retention time in their occupational exposure sites. This case study is a good example to cover that LCA with probabilistic risk analysis tool can supply various significant information such as statistical distribution including personal/environmental exposure level, daily time activity pattern and individual susceptibility. Further research is needed for investigating real data of these input variables and personal exposure concentration and application of this study methodology.

• Journal of Nutrition and Health
• /
• v.37 no.5
• /
• pp.385-393
• /
• 2004

This study examined the relations of educational level and life-style behaviors to the obesity. A total of 507 male adults aged 30 - 50 years completed the self-reported questionnaires. Educational level was used for measuring socioeconomic status. Activity at work, leisure-time activity and TV watching were measured for life-style behaviors related to physical activity, and some demographic and family history of disease as well. Subjects were categorized as obese when BMI was equal to or over 25kg/$m^2$, in which 19.7％ resulted obesity. Using multivariate logistic regression, the association between the measured factors and obesity was assessed. The odds ratios (OR) for risk of obesity did not differ with either age or monthly income. Subjects who completed high school (OR = 0.36; 95％ CI = 0.20 - 0.66) or university (OR = 0.34; 95％ CI = 0.16 - 0.71) had lower risk of obesity than those with education below middle school. Those with moderate activity level at work (OR = 0.41; 95％ CI = 0.24 - 0.72) showed lower risk of obesity than in inactive ones. The subjects watching TV more than 3.5 hr/day presented higher risk of obesity (OR = 2.46; 95％ CI = 1.28 - 4.74), compared with those watching TV less than 1.5 hr/day. The higher risk of obesity observed in high level of leisure time activity than in low one was considered due to that physical activity at work and leisure-time might counteract each other. Educational level and activity at work or leisure-time activity or TV watching were jointed and categorized, and then OR for obesity was estimated. The extent of obesity risk at a given level of each work activity or leisure-time activity or TV watching was different depending the educational level, which was significantly high when educational level was below middle school. Educational difference had no effect on activity level at work. However, higher educational attainment increased the leisure activity and reduced TV watching (p＜0.05), indicating that low education tended to contribute to more sedentary life-style. The findings of this study is concluded that low education was related to obesity in adult males, and its relation can partly be explained through acquiring inactive life-style behaviors. Individuals with low education might be more susceptible to the risk factors of obesity.

• Journal of the East Asian Society of Dietary Life
• /
• v.27 no.4
• /
• pp.450-458
• /
• 2017

The purpose of this study was to investigate the levels of risk perception characteristics for food risk elements using a psychometric paradigm from 298 university students in Yeungnam region, Korea, by a self-administered questionnaire. The respondents showed the highest level of risk concern about radioactive contaminated foods and the lowest level about GM (genetically modified) foods. In the risk perception characteristics for food risk elements, they perceived radioactive contaminated foods as a catastrophic, worried, new, and uncontrollable risk. In addition, they regarded food additives and foodborne illness as a chronic, controllable, old, and scientifically and individually known risk. According to the results of the factor analysis for risk perception characteristics, dread and unknown were categorized. In the risk perception map, mad cow disease, heavy metal contaminated foods, and radioactive contaminated foods were considered as a dreaded and unknown risk, whereas pesticide residues and GM foods were perceived as a less dreaded and unknown risk. Additionally, food additives and foodborne illness were regarded as a less dreaded and known risk and endocrine disruptors and avian influenza as a dreaded and known risk. These results imply that risk perception characteristics of consumers should be considered to establish strategies for risk communication in food science.

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.7
• /
• pp.2713-2717
• /
• 2015

Background: Possible associations between the single nucleotide polymorphism (SNP) rs8034191 in the aminoglycosidephosphotransferase domain containing 1 (AGPHD1) gene and lung cancer risk have been studied by many researchers but the results have been contradictory. Materials and Methods: A computerized search for publications on rs8034191 and lung cancer risk was performed. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated to assess the association between rs8034191 and lung cancer risk with 13 selected case-control studies. Sensitivity analysis, test of heterogeneity, cumulative meta-analysis, and assessment of bias were also performed. Results: A significant association between rs8034191 and lung cancer susceptibility was found using the dominant genetic model (OR=1.344, 95% CI: 1.285-1.406), the additive genetic model (OR=1.613, 95% CI: 1.503-1.730), and the recessive genetic model (OR=1.408, 95% CI: 1.319-1.503). Moreover, an increased lung cancer risk was found with all genetic models after stratification of ethnicity. Conclusions: The association between rs8034191 and lung cancer risk was significant using multiple genetic models, suggesting that rs8034191 is a risk factor for lung cancer. Further functional studies of this polymorphism and lung cancer risk are warranted.

• Journal of Korean Academy of Nursing
• /
• v.41 no.2
• /
• pp.149-156
• /
• 2011

Purpose: This study seeks to examine prevalence, risk factors, and quality of life of Korean adults with Chronic Obstructive Pulmonary Disease (COPD). Methods: From the database of the Fourth Korean National Health and Nutrition Examination Survey (KNHANES IV-1, 2008), the researchers selected 1,458 adults over the age of 45. The original study was a population-based epidemiological survey of health and nutrition with a stratified multistage clustered probability design. Prevalence of COPD was computed on the basis of the sampling weight. Data were analyzed using descriptive statistics, ${\chi}^2$ test, t-test and multiple logistic regression with the SPSS WIN 18.0 and SAS Ver. 9.1 program. Results: The prevalence of COPD was 18.0% among people older than 45 yr. The prevalence of current smokers was 19.7% in this population and 26.3% in individuals with COPD. Age, gender, education, and smoking levels were found to be risk factors for COPD. Significant difference in quality of life was founded between adults with COPD and the healthy controls. Conclusion: The results of this study indicate that COPD is a highly prevalent disease in Korea. To reduce the prevalence of COPD and improve health-related quality of life in patients with COPD, nursing interventions must focus on prevention of risk factors.

• The Journal of Health Technology Assessment
• /
• v.6 no.2
• /
• pp.133-141
• /
• 2018

Objectives: In the past, the pharmaceutical drug heparin was mostly used as the anticoagulant for continuous renal replacement therapy (CRRT), but the duration time is long to have the risk of a bleeding adverse effect, and in that case the drug therapy Nafamostat mesilate was utilized instead, as it is more safe in this case, with a short half-life and is increasing in use to permit lower concerns for bleeding incidents. However, there are insufficient number of large-scale studies on the comparison of Nafamostat mesilate and heparin. Methods: In this study, a systematic review are used to compare the bleeding risk of Nafamostat mesilate and Heparin, as subjected to patients and procedures for measuring risks performed with a CRRT, and the filter life span is to be evaluated as well in this patients. Results: As a result of literature review search, a total of 6 studies were included in systematic review. The reducing risk of bleeding and filter life span was analyzed. The retrospective cohort studies confirm that Nafamostat mesilate is less at risk of bleeding than heparin. And a cohort study confirms that Nafamostat mesilate is longer filter lifespan than heparin and randomized controlled trial studies show that Nafamostat mesilate is longer filter lifespan than not using the anticoagulants. Conclusion: Nafamostat mesilate is considered to be a good therapeutic option because it has a longer filter life span as well as the advantage of reducing bleeding.

• The Korean Journal of Community Living Science
• /
• v.22 no.3
• /
• pp.429-444
• /
• 2011

The objective of this study was to identify the risk factor and protection factor related to suicide ideation in each life course based on an ecological-system perspective. A questionnaire was carried out for 393 adolescents, 473 adults and 376 aged men living nationwide. The results are as follows. First, the suicide ideation was low with 1.78 points in the full mark of 5 points. Second, the difference in suicide ideation, depression, hopelessness, stress in the organic system variables, family solidarity in the micro system variables, intermediate system variables, residence, the existence/inexistence of counselling center and the influence of mass media in mezo system variables in each life course were significant. Third, the relative influence of organic system variables on the suicide ideation were largest in all life courses. Further, the depression and the influence of mass media in all life courses were a risk factor of suicide ideation and stress was also a risk factor of suicide ideation in the case of adolescents and the aged. When examining protection factors of suicide ideation, family solidarity, minute as it is, works as the protection factor of suicide ideation in the case of adolescents. For the adults, living in a metropolis was a protection factor from suicide ideation. For the aged, family solidarity, family history of suicide and adult children's attention to their friends and neighbors (intermediate system variable) were protection factors from suicide ideation. I suggested that policy, service, counseling and educational program proper to each life course were necessary to lower risk factors of suicide ideation and to improve protection factors.

• Research in Community and Public Health Nursing
• /
• v.12 no.2
• /
• pp.468-481
• /
• 2001

The purpose of this study was to collect basic data to develop school health policy and health promotion program. This survey measured the levels of risk behaviors in six categories in a middle school students in Kyungju(n=490). The data was collected from November to December 2000. It was done using a 1999 version of the Youth Risk Behavior Survey of CDC, which was translated and make a partial modification. The major results were as follows. Many middle school students engaged in behaviors that will increase the likelihood of death or illness. 1) A high percentage of middle school students engaged in behaviors that contribute to unintentional injuries and school-related violence (42.1 -78%) 2) Students who perceived their school life are happy experienced more depression(p=.000) and Students who perceived their school and family life are so-and-so seriously considered attempting suicide(p = .000) than other subgroup. 3) In spite of they were normal weight, 14.5% of students considered themselves overweight. 4) There was significantly difference or correlation between health risk behaviors and grade, parents educational level perception of school life and performance, perception of family life and religion. Based on this results of study, it is necessary to develop school health program and school health policy to prevent health risk behaviors and improve health promotion especially considering characteristics of middle school students.