• Title/Summary/Keyword: leukocytosis

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Group B Streptococcal Renal Abscess in a 17-Year-Old Girl with Type 1 Diabetes Mellitus

  • Oh, Kyeong Eun;Yim, Hyung Eun;Yoo, Kee Hwan
    • Childhood Kidney Diseases
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    • v.24 no.1
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    • pp.53-57
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    • 2020
  • Streptococcus agalactiae or group B streptococcus (GBS) is associated with infections in neonates and pregnant women. Herein, we describe a rare case of GBS renal abscess with peritonitis and pleural effusion in a 17-year-old girl with type 1 diabetes mellitus. The girl was admitted due to fever and right flank pain. Laboratory findings included leukocytosis and increased C-reactive protein level and erythrocyte sedimentation rate. Her serum glucose level was 484 mg/dL. Urinalysis showed no pyuria. Renal sonography revealed parenchymal swelling in the right kidney. The patient was administered intravenous cefotaxime. Urine and blood cultures were negative. Fever seemed to improve, but the following day, she complained of abdominal pain and fever. Antibiotic was switched to imipenem, and abdominal and pelvic CT revealed a ruptured right renal abscess, peritonitis, and bilateral pleural effusion with atelectasis. Pigtail catheter drainage of the abscess was performed. Culture from the abscess was positive for GBS, and fever subsided 2 days after the drainage. She was discharged with oral cefixime. The clinical course of urinary tract infections (UTIs) can be atypical in patients with diabetes, and GBS can be a cause of UTIs. Prompt diagnosis and management are necessary to prevent complications in patients showing atypical courses.

Investigation of canine dirofilariasis and brucellosis in free roaming dogs from public animal shelters in Gwangju area (광주지역 동물보호소내 유기견의 개심장사상충과 개 브루셀라병 감염 실태조사)

  • Koh, Ba-Ra-Da;Na, Ho-Myung;Jang, Mi-Sun;Kim, Ji-Yeon;Park, Seong-Do
    • Korean Journal of Veterinary Service
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    • v.30 no.1
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    • pp.155-164
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    • 2007
  • This study was conducted to investigate the prevalence of canine heartworm infections, canine brucellosis and hematologic values from 153 free roaming dogs in the area of Gwangju city from March to November 2006. Nineteen (12.4%) of 153 samples tested with modified Knott's technique showed positive reaction for microfilariae. Polymerase chain reaction using specific primers for D immitis amplified the expected product from all samples of 19 microfilaremic canine blood samples as determined by the modified Knott's test for microfilariae. The seasonal infection rates of microfilariae were higher in the spring season (10/19, 52.6%) than in the other seasons. The major hematological findings in microfilaremic dogs were mild leukocytosis and mild monocytosis. A total of 100 dogs randomly selected from 153 free roaming dogs were negative for canine brucellosis by serological test using immunochromatographic antibody test kit.

Could the Platelet-to-Lymphocyte Ratio be a Novel Marker for Predicting Invasiveness of Cervical Pathologies?

  • Kose, Mesut;Celik, Fatih;Kose, Seda Kayman;Arioz, Dagistan Tolga;Yilmazer, Mehmet
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.3
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    • pp.923-926
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    • 2015
  • Purpose: To determine whether the preoperative platelet to lymphocyte ratio (PLR) could predict invasiveness of cervical pathologies. Materials and Methods: Patients with preinvasive and invasive diseases were reviewed retrospectively, over a nine-year period, 2005-2014. The pathological records and completed blood counts of the patients were collected and recorded in the SPSS program. Patients were divided in two groups, preinvasive and invasive. Results: The median PLR was significantly higher in the invasive group than in the preinvasive group (p=0.03). There was a correlation between invasion of cervical cancer and white blood cell count, red cell distributing width (RDW), neutrophil-lymphocyte ratio (NLR), and PLR. Conclusions: This study showed that patients with uterine cervical cancer may present with leukocytosis, increased RDW, NLR and PLR. These cheap and easily available parameters, especially PLR, may provide useful information about the invasiveness of cervical lesions.

Influence of Dexamethasone on the Recrudescence of Theileria sergenti in Carrier Calves (Theileria sergenti 불현성감염우(不顯性感染牛)에 대(對)한 Dexamethasone의 영향(影響)에 관(關)한 연구(硏究))

  • Son, Jae-young;Ko, Ki-whan
    • Korean Journal of Veterinary Research
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    • v.27 no.1
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    • pp.93-99
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    • 1987
  • A study was conducted to observe the effects of dexamethasone sodium 21 phosphate injection in different amounts, intervals and times on the fluctuation of the parasitized erythrocytes in the peripheral blood of the T. sergenti carrier calves. A total of 31 calves including 15 Holstein and 16 Korean native male calves aged 6-12 months (125-300kg) was used. Results observed were as follows. 1. The calves injected 0.2mg/kg body weight two and three times in 48 hour intervals and 5 times in 24 hour intervals observed that 2 out of 2 heads, 3 out of 6 heads, and 4 out of 5 heads, respectively were substantially increased parasitized erythrocytes in the blood for 3-11 days after the first injection and continued to 2-10 days. 2. However, the calves injected once with 0.1mg/kg body weight and all control calves showed no visible change of the parasitized erythrocytes in the blood during the experimental period. 3. The animals injected over 2 times with 0.2mg/kg body weight tended to be decreased the number of erythrocytes, hemoglobin concentration and PCV for 2-3 days after first injection and continued about one week. 4. All animals injected the dexamethasone were observed the neutrophilic leukocytosis, eosinopenea and lymphopenea until 48 hours after injection.

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Flurbiprofen toxicity in 2 dogs (두 마리 개에서의 flurbiprofen 중독 2례)

  • Lee, Ye-Hyun;Nam, Eui-Hwa;Park, Seol-Hee;Song, Chi-Youn;Lee, Yong-Uk;Lee, Jong-Myung;Park, Jung-Hoon;Hwang, Cheol-Yong
    • Korean Journal of Veterinary Research
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    • v.53 no.3
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    • pp.177-180
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    • 2013
  • Two dogs were presented with melena, vomiting and depression after accidental swallowing of candy form of Strepsils (flurbiprofen), which is one of non-steroidal anti-inflammatory drugs used in human medicine for controlling a sore throat. These dogs had common signs of anemia induced by gastrointestinal ulceration and hemorrhage with azotemia and leukocytosis. The dogs were treated with blood transfusion, fluid therapy, proton-pump inhibitor, antiemetics, mucus protectant and antibiotic. Although most of clinical signs of two dogs were resolved, azotemic problem with evidence of renal injury have remained.

Ultrasonographic Diagnosis of Pneumoperitoneum Associated with a Mast Cell Tumor in a Dog (개에서 비만세포종과 관련된 기복증의 초음파학적 진단례)

  • Wang, Ji-Hwan;Park, Ki-Tae;Lee, Kyung-Woo;Yeon, Seong-Chan;Lee, Hyo-Jong;Lee, Hee-Chun
    • Journal of Veterinary Clinics
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    • v.27 no.4
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    • pp.483-487
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    • 2010
  • A 7-year-old female maltese dog with anorexia and vomiting for a week, and left axillary and perineal mass was admitted to Gyeongsang National University Veterinary Teaching Hospital. CBC revealed mild leukocytosis and severe anemia. Abdominal radiography revealed multiple gas opacities in upper abdomen. On ultrasonography, large amount of echogenic free abdominal fluid were detected. In addition, There are enhanced peritoneal strip sign (EPSS) indicating peumoperitoneum in the upper abdomen. Fine needle aspiration of the mass was performed and the result was mast cell tumor. Duodenal perforation caused by mast cell tumor was identified on laparotomy.

Medical Imaging of Pyothorax in a Dog (개에서 농흉증의 영상의학적 접근)

  • Choi, Ho-Jung;Lee, Young-Won;Park, Ki-Tae;Wang, Ji-Hwan;Kim, Young-Ki;Yeon, Seong-Chan;Lee, Hyo-Jong;Lee, Hee-Chun
    • Journal of Veterinary Clinics
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    • v.27 no.1
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    • pp.107-112
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    • 2010
  • A 3-years-old female Pointer was evaluated for anorexia, dyspnea and exercise intolerance for 10 days. Auscultation revealed muffling of heart sound. There were leukocytosis, anemia, hypoalbuminaemia and hyperglobulinaemia on the blood profiles. Radiography showed severe pleural effusion. Thorax ultrasonographs described traped pleural effusion, pericardial effusion and collapsed right lung lobe(s). On CT images, thoracic neoplasia and lung torsion were ruled-out. Thoracocentesis with thoracoscopy and bacterial culture revealed pyothorax and pleuritis. The diagnosis of pyothorax in dogs and cats is based on clinical signs, radiography, thoracocentesis and cytology and culture of the exudate. In this case, various diagnostic medical imaging techniques (radiography, ultrasonography, CT and thoracoscopy) were used for diagnosis of pyothorax.

Diagnosis of Anaplasmosis by PCR and Long Term Medication in a Dog (PCR을 이용한 개의 아나플라즈마병 진단과 장기간 치료)

  • Lee Sook-jin;Lee Mi-jin;Chae Joon-seok;Na Ki-jeong
    • Journal of Veterinary Clinics
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    • v.22 no.2
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    • pp.170-173
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    • 2005
  • A 4-year-old female Shunauzer dog was referred to the Veterinary Teaching Hospital of Chungbuk National University due to anorexia and depression. The dog had a history of regular walking on grass fields, weight loss, and hyperthermia $(40.6^{\circ}C)$. In the physical examination, lymph node enlargement was confirmed. Complete blood count result revealed leukocytosis and thrombocytopenia but there was no decreasing of red blood cells. On blood chemistry, serum ALP, GGT, CPK, and LDH were elevated. Abdominal radiograph showed splenomegaly. Anaplasma platys infection was suspected with inclusion body-like substances in platelets on blood smear. Anaplasma platys was confirmed by PCR. On the basis of laboratory examination, final diagnosis was anaplasmosis. Treatment was followed for 3 months with tetracycline and doxycycline. The patient was monitored every week during the treatment. The patient has recovered to normal condition without any clinical signs. We are going to emphasize the need of PCR technique in diagnosis and to report the possibility of long term treatment more than two months in rickettial disease.

Systemic Lupus Erythematosus in a Dog, Suspexted Systemic Lupus Erythematosus in a Dog, and Autoimmune Thrombocytopenic Purpura Hemorrhagica in a Dog (개에 있어서 전신성홍반성루프스 1예와 전신성혼반성루프스 의증 1예 및 자가면역성혈소판감소성출혈성자반병 1예)

  • 이창우;나기정;임정식;서정욱
    • Journal of Veterinary Clinics
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    • v.13 no.1
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    • pp.81-86
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    • 1996
  • Systemic lupus erythematosus in a dog, suspected systemic lupus erythematosus in a dog, and autoimmune thrombocytopenic purpura hemmorrhagica in a dog are reported. A fice-year old, female Chihuahua (Case 1) showed initially hemorrhagic diathesis and purpura hemorrhagica. Afterward, it showed polymyositis and polyarthritis. LE-cell was demonstrated on LE-cell preparation trom blood. Systemic lupus erythematosus was diagnosed. This reponded well to the immunosuppressants, but developed iatrogenic Cushing syndrome and steroid hepatopathy. A two-and-half-year old, male toy poodle (Case 2) had chief complaint of red urine. Occult blood test for the urine sediment. This did not respond at all to antibiotics and carbazochrome, which is one of systemic coagulants. LE-cell was demonstrated on LE-cell preparation from blood. This responded relatively well to immunosupressants such as prenisolone, azathioprine and cyclophosphamide. systemic lupus erythematosus is suspected. A nine-year-and-three-month old, female Maltese (Case 3), which had history of congestive heart failure and ovariohysterectomy showed purpura hemorrhagica in the skin of chest. This had severe thrombocytopenia and leukocytosis. As prednisolone was administered before immunological examination or demonstration of LE-cell, it was impossible to diagnose whether purpura hemorrhagica developed as a member of systemic lupus erythematosus or independent of systemic lupus erythematosus. This responded well to prednisolone, and so autoimmune thrombocytopenic purpura hemorrhagica was diagnosed.

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A Case of Acute Intoxication with Glyphosate and Oxyfluorfen Containing Powder Herbicide ($Daejangun^{(R)}$) (Oxyfluoren이 함유된 입제 glyphosate 제초제(대장군) 급성 중독 1예)

  • Lee Seung Hee;Yi Kum Ho;Yoo Sung-Soo;Roh Heung-Keun
    • Journal of The Korean Society of Clinical Toxicology
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    • v.3 no.2
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    • pp.110-113
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    • 2005
  • Glyphosate containing herbicides are an alternative to paraquat and have been widely used with increasing frequency in suicide attempts throughout Asia. It is an organophosphorus compound that is not a cholinesterase inhibitor. Daejangun powder consists of glyphosate ammonium, surfactant and another herbicide, oxyfluorfen. A 60-year-old man ingested about 300 g of Daejangun powder with 500 ml of water in a suicide attempt. He was brought to emergency room 6 hours after the ingestion and showed severe metabolic acidosis (pH 6.75), marked leukocytosis (WBC 35,800/$mm^3$), hypoglycemia (glucose 13 mg/dL) and increased liver enzymes (AST/ALT 1,683/418 IU/L). Later he developed aspiration pneumonia, acute renal failure and hyperchloremic acidosis. Upper gastrointestinal endoscopy which performed 5 days after the ingestion revealed corrosive injuries (grade 1) in both esophagus and stomach. However, intensive treatment with supportive measures improved the abnormal findings almost completely 4 weeks after the ingestion.

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