Journal of Veterinary Clinics (한국임상수의학회지)

The Korean Society of Veterinary Clinics (한국임상수의학회)
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Diagnosis of Anaplasmosis by PCR and Long Term Medication in a Dog

PCR을 이용한 개의 아나플라즈마병 진단과 장기간 치료

  • Lee Sook-jin (Dept. of Veterinary Laboratory Medicine, College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University) ;
  • Lee Mi-jin (Dept. of Vet. Internal Medicince & Laboratory Medicine, College of Veterinary Medicine, Chonbuk National University) ;
  • Chae Joon-seok (Dept. of Vet. Internal Medicince & Laboratory Medicine, College of Veterinary Medicine, Chonbuk National University) ;
  • Na Ki-jeong (Dept. of Veterinary Laboratory Medicine, College of Veterinary Medicine and Research Institute of Veterinary Medicine, Chungbuk National University)
  • 이숙진 (충북대학교 수의과대학 및 동물의학연구소) ;
  • 이미진 (전북대학교 수의과대학) ;
  • 채준석 (전북대학교 수의과대학) ;
  • 나기정 (충북대학교 수의과대학 및 동물의학연구소)
  • Published : 2005.06.01
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Abstract

A 4-year-old female Shunauzer dog was referred to the Veterinary Teaching Hospital of Chungbuk National University due to anorexia and depression. The dog had a history of regular walking on grass fields, weight loss, and hyperthermia $(40.6^{\circ}C)$. In the physical examination, lymph node enlargement was confirmed. Complete blood count result revealed leukocytosis and thrombocytopenia but there was no decreasing of red blood cells. On blood chemistry, serum ALP, GGT, CPK, and LDH were elevated. Abdominal radiograph showed splenomegaly. Anaplasma platys infection was suspected with inclusion body-like substances in platelets on blood smear. Anaplasma platys was confirmed by PCR. On the basis of laboratory examination, final diagnosis was anaplasmosis. Treatment was followed for 3 months with tetracycline and doxycycline. The patient was monitored every week during the treatment. The patient has recovered to normal condition without any clinical signs. We are going to emphasize the need of PCR technique in diagnosis and to report the possibility of long term treatment more than two months in rickettial disease.

Keywords

References

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