• YAKHAK HOEJI
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• v.47 no.1
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• pp.25-30
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• 2003

This study is performed to investigate the effects of citrus essential oils on melanin production in B16 melanoma cells. Five kinds of citrus essential oils (Bergamot, Grapefruit, Lemon, Mandarin, Petigrain) did not have any influence on DPPH radical scavenger activity, cell growth and cytotoxicity in B16 melanoma cells. Both mandarin and petigrain essential oils dose-dependently inhibited purified tyrosinase activity, but bergamot did not. In 1$\mu$M MSH-stimulated B16 melanoma cells, all of 5 citrus essential oils inhibited melanin production in a dose dependent manner. From the above results, it is possible that citrus essential oils may be developed to be an anti-melanogenesis agent on the basis of their inhibitory effect on MSH-induced melanin production.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.48
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• pp.41-48
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• 2003

The number of natural products obtained from plants has now reached over 100,000 and new chemical compounds are being discovered ever year. Medicinal and Aromatic plants and their extracts have been used for centuries to relieve pain, aid healing, kill bacteria and insects are important as the antifungal and anti-herbivore agents with further compounds being involved in the symbiotic associations. Although their functions in plants have not been fully established, it is Known that some substances have growth regulatory properties while others are involved in pollination and seed dispersal. The complex nature of these chemicals are usually produced in various types of secretory structures which is an important character of a plant family and also influenced and controlled by genetic and ecological factors. Detailed anatomical description of these structures ave relevant to the market value of the plants, the verification of authenticity of a given species and for the detection of substitution or adulteration. Volatile oils are used for their therapeutic action for flavoring of lemon, in perfumery of rose or as starting materials for the synthesis of other compounds of turpentine. For therapeutic purposes they are administered as inhalations of eucalyptus oil, peppermint oil, as gargles and mouthwashes of thymol and transdermally many essential oils including those of lavender, etc. With these current trend for using volatile components in essential oil will be increasing in the future in Korea and in the world as well.

• Journal of Microbiology and Biotechnology
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• v.23 no.6
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• pp.771-778
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• 2013

Essential oils are increasingly of interest for use as novel drugs acting as antimicrobial and antiviral agents. In the present study, we report the in vitro antiviral activities of 29 essential oils, extracted from Chinese indigenous aromatic plants, against the tobacco mosaic virus (TMV). Of these essential oils, those oils from ginger, lemon, tea tree, tangerine peel, artemisia, and lemongrass effected a more than 50% inhibition of TMV at 100 ${\mu}g/ml$. In addition, the mode of antiviral action of the active essential oils was also determined. Essential oils isolated from artemisia and lemongrass possessed potent inactivation and curative effects in vivo and had a directly passivating effect on TMV infection in a dose-dependent manner. However, all other active essential oils exhibited a moderate protective effect in vivo. The chemical constitutions of the essential oils from ginger, lemon, tea tree, tangerine peel, artemisia, and lemongrass were identified by gas chromatography and gas chromatography-mass spectrometry. The major components of these essential oils were ${\alpha}$-zingiberene (35.21%), limonene (76.25%), terpinen-4-ol (41.20%), limonene (80.95%), 1,8-cineole (27.45%), and terpinolene (10.67%). The curative effects of 10 individual compounds from the active essential oils on TMV infection were also examined in vivo. The compounds from citronellal, limonene, 1,8-cineole, and ${\alpha}$-zingiberene effected a more than 40% inhibition rate for TMV infection, and the other compounds demonstrated moderate activities at 320 ${\mu}g/ml$ in vivo. There results indicate that the essential oils isolated from artemisia and lemongrass, and the individual compound citronellal, have the potential to be used as an effective alternative for the treatment of tobacco plants infected with TMV under greenhouse conditions.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2000.11a
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• pp.44-47
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• 2000

본 연구에서는 향이 인간에 미치는 영향을 EEG의 시계열 분석을 통해 알아보았다. 피험자는 20대 초반의 후각자애가 없는 30명(남녀 각각 15명)을 대상으로 하여, 국제 기준 전극법을 사용하여 Fz과 Cz에서 뇌파를 기록하였다. 100%의 Rose oil Bulgarian, Lemon oil Mistitano, Jasmine abs, Lavender oil France, Peppermint oil을 실험 시약으로 사용하였다. 각 향 자극에 대하여 1분 동안의 측정을 10초 간격으로 구분하여 $\alpha/(\alpha+\beta)$ 비와 $\beta/(\alpha+\beta)$ 대역의 비를 비교 분석하였다. 30초까지는 안정과 향 자극간의 차이가 증대되는 성향을 보였으나 50초부터는 감소되는 경향을 보였다. 본 연구를 통해 향간의 차이가 자극제시 후 30초 일 때 가장 큰 것으로 나타났다고 이 시간을 기준으로 각 향의 선호도를 분석하였다.

• Journal of Korean Biological Nursing Science
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• v.16 no.3
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• pp.219-225
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• 2014

Purpose: This study was aimed to evaluate the effect of blending oils on atopic dermatitis (AD) model of NC/Nga mice. Methods: Adult NC/Nga mice were assigned to 1 of 3 groups: control group (C, n=8), experimental group [AD-induced group, blending oil-treated group (E=8, 8)]. Mice in the E group were given a treatment of blending oils such as Lavender, Rosemary and Lemon Balm (LRL) for 2 sessions (every day) for 6 days. Results: The AD-induced mice with LRL blending oils treatment showed a significant decrease in epidermal thickness, number of mast cells and degranulation, expression of TNF-${\alpha}$ and scoring of sensual assessment. Conclusion: LRL blending oils may be a putative resource for the cure of or treatment of AD by the diminution of AD-pathological factors such as the epidermal thickness, the number of mast cells and degranulation as well as the expression of TNF-${\alpha}$.

• Journal of the Ergonomics Society of Korea
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• v.20 no.3
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• pp.1-9
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• 2001

In the present study, the correlation between subjective assessment and EEG for essential odors were investigated quantitatively. EEG signals were measured from 19 electrodes according to the International 10-20 system (Fp1, Fp2, F3/4, F7/8, Fz, C3/4, Cz, P3/4, Pz, T3/4, T5/6, O1/2) from 8 healthy males subjects for four odor(Rose oil bulgarian, Lemon oil misitano, jasmin abs, Laverder oil france (KIMEX co. Ltd) conditions. The result of the subjective assessment shows the most pleasant odor for each subject. and the power spectrum of ${\alpha}/({\alpha}+{\beta})$ of EEG signals from the most pleasant odor was compared with those from the control condition, which has no odor at all. Power spectrum of ${\alpha}/({\alpha}+{\beta})$ of EEG from the most pleasant odor was increased significantly at T4, T6 compared to the control condition. This result implies that the parameter, power spectrum of ${\alpha}/({\alpha}+{\beta})$, could be an important index for signifying the levels of pleasantness for odors.

• Proceedings of the Korean Society for Emotion and Sensibility Conference
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• 2000.11a
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• pp.38-43
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• 2000

In this present study, the correlation between subjective preference of essential odors and EEG response were investigated quantitatively. EEG signals were measured from 19 electrodes according to the International 10-20 system (Fpl, Fp2, F2/4, F7/8, Fz, C3/4, Cz, P3/4, Pz, T3/4, T5/6, Ol/2) from 8 healthy males subjects in four odor conditions. Four odor conditions (Rose oil bulgarian, Lemon oil misitano, Jasmin abs, Laverder iol france (KIMEX co. Ltd)) were applied for each subject in the experiment. Through the subjective evaluation, the most pleasant odor for each subject was determined. The power spectrum of ${\alpha}$/${\beta}$ of EEG signals from the most pleasant odor was compared with those from the control condition, which has no odor at all. It was observed that the power spectrum of ${\alpha}$/${\beta}$ of EEG from the most pleasant odor was increased significantly on F3, F3, F4,74 comparing to the control condition. This result indicates that the power spectrum of ai${\beta}$ could be a new index for measuring the levels of pleasantness of odors.

• The Korean Journal of Pesticide Science
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• v.12 no.2
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• pp.162-167
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• 2008

To enhance the control efficacy against cockroaches in dwelling space, repellent ("Push") was set down on one comer and a poison bait including attractant ("Pull") was on the opposite side. And we tested the control efficacy of Push-Pull strategy by behavior-stimuli of cockroaches. In a mini-field test, German cockroach males primarily chose shelters nearest to the attractant-treated surfaces and farthest from the repellent-treated surfaces. The consumption of food or bait was also highest from food nearest to the preferred shelters by push-pull effect. We evaluated the push-pull insecticidal efficacies of five essential oils belong to Citrus plant, namely, grapefruit, lemon, lime, orange, and petitgrain. The combined push-pull treatments appeared to be faster and higher insecticidal effects than single (pull) treatment, and the repellent efficacy of Citrus oils was in the order of grapefruit > lemon > lime > orange > petitgrain. Therefore, we propose the effective control of the german cockroach using Citrus oils as repellents and push-pull method into a limited area.

• The Korean Journal of Pesticide Science
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• v.17 no.4
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• pp.419-427
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• 2013

The insecticidal activity of 124 plant essential oils and control efficacy of six experimental spray formulations (SF) containing 0.25, 0.5, 1, 2.5, 5, and 10% of the selected oils was examined against both nymph and adult of the citrus flatid planthopper, Metcalfa pruinosa using direct contact applications (leaf dipping and spray). Reponses varied according to dose (1,000 and 500 mg/L). When exposed at 1,000 mg/L for 24 h using leaf dipping assay, 19 essential oils showed strong mortality (100%) among 124 essential oils screened. At 500 mg/L, 100% mortality was observed in cinnamon technical, cinnamon green leaf, cinnamon #500, cassia tree, citronella java and pennyroyal followed by origanum, thyme white, grapefruit, savory, fennel sweet, aniseed and cinnamon bark showed considerable mortality (93.3-80%) against nymphs of M. pruinosa. The moderate mortality (73.3-60%) was found in thyme red, tagetes, calamus, lemoneucalptus and geranium. Oils applied as SF-10% sprays provided 100 % mortality against adult M. pruinosa. One hundred mortalities were achieved in cinnamon technical at >SF-0.5 formulation, in cinnamon #500, cinnamon green leaf and penny royal at >SF-2.5. To reduce the level of highly toxic synthetic insecticides in the agricultural environment, the active essential oils as potential larvicides could be provided as an alternative to control M. pruinosa populations.

• Journal of Digital Convergence
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• v.14 no.8
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• pp.547-553
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• 2016

This study was conducted to look at the antimicrobial synergistic effect of blended oil into the target skin flora. The essential oils used in antimicrobial test were 100% eucalyptus (EU), lemon (LE), lavender (LA) and four blended oils, EU+LE, LE+LA, EU+LA, and, EU+LE+LA in ratio of 1:1 and 1:1:1 respectively. As a result, LE showed the highest, LA showed the lowest antimicrobial activity among single oil group. In blended oil group, antimicrobial activity of the EU + LA showed significantly increasing effect than the sum of the antimicrobial activity of the single oil. However, the antimicrobial effects of the blend of three oils did not show any synergistic effect. This result showed that the interaction between the chemical components constituting the oil than the number of blended oil seems more significant on the synergistic effect. Therefore, blending essential oil based on scientific evidence becomes more necessary in the future.