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http://dx.doi.org/10.7586/jkbns.2014.16.3.219

The Effect of Essential Oil on Atopic Dermatitis Model of NC/Nga Mice  

Han, Sun Hee (Department of Nursing, Wonkwang Health Science University)
Seo, Young Mi (Department of Nursing, Wonkwang Health Science University)
Publication Information
Journal of Korean Biological Nursing Science / v.16, no.3, 2014 , pp. 219-225 More about this Journal
Abstract
Purpose: This study was aimed to evaluate the effect of blending oils on atopic dermatitis (AD) model of NC/Nga mice. Methods: Adult NC/Nga mice were assigned to 1 of 3 groups: control group (C, n=8), experimental group [AD-induced group, blending oil-treated group (E=8, 8)]. Mice in the E group were given a treatment of blending oils such as Lavender, Rosemary and Lemon Balm (LRL) for 2 sessions (every day) for 6 days. Results: The AD-induced mice with LRL blending oils treatment showed a significant decrease in epidermal thickness, number of mast cells and degranulation, expression of TNF-${\alpha}$ and scoring of sensual assessment. Conclusion: LRL blending oils may be a putative resource for the cure of or treatment of AD by the diminution of AD-pathological factors such as the epidermal thickness, the number of mast cells and degranulation as well as the expression of TNF-${\alpha}$.
Keywords
Atopic dermatitis; Essential oil; Skin;
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Times Cited By KSCI : 8  (Citation Analysis)
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