• 대한임상검사과학회지
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• 제54권2호
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• pp.79-94
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• 2022

COVID-19로 인한 높은 전염성과 호흡기 질환의 심각성 때문에, 전염의 확산을 더 잘 모니터링하고 예방하기 위해 경제적이고 정확한 검사가 필요하다. COVID-19 대유행의 초기 단계에서 SARS-CoV-2의 구조적 및 분자적 특성이 밝혀짐에 따라, 많은 COVID-19 진단 키트 제조업체들은 진단 테스트의 설계, 개발, 검증 및 구현에 적극적으로 투자했다. 현재, SARS-CoV-2에 대한 진단검사로써 신속한 항원, 특정 IgG 및 IgM 항체검사를 위한 면역 혈청학적 검사 그리고 분자 진단 검사가 가장 널리 사용되고 검증된 기술이다. 분자 진단 분석법은 SARS-CoV-2에 감염된 것으로 의심되는 개인에서 바이러스 RNA를 직접 검출하기 위한 gold standard이다. 항체 기반 혈청 검사는 지역사회에서 COVID-19 유병률을 결정하고 면역력을 획득한 개인을 식별하는 데 사용되는 간접 검사이다. 본 논문에서는 시판되고 FDA가 승인한 분자 및 면역학적 진단 측정을 평가하여 성능 특성을 분석하였다.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 2004년도 ICCAS
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• pp.1324-1329
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• 2004

In this article we have tested stability of classifier based on fuzzy similarity in generalized Lukasiewicz structure. Two different tests for stability was made:In on test stability was checked respect to weight parameters and other test was carried out for idealvectors. Tests have made with three different classification problems.

• Computers and Concrete
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• 제7권2호
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• pp.191-202
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• 2010

A laboratory investigation was conducted to characterize the constitutive property behavior of Cor-Tuf, an ultra-high-performance composite concrete. Mechanical property tests (hydrostatic compression, unconfined compression (UC), triaxial compression (TXC), unconfined direct pull (DP), uniaxial strain, and uniaxial-strain-load/constant-volumetric-strain tests) were performed on specimens prepared from concrete mixtures with and without steel fibers. From the UC and TXC test results, compression failure surfaces were developed for both sets of specimens. Both failure surfaces exhibited a continuous increase in maximum principal stress difference with increasing confining stress. The DP tests results determined the unconfined tensile strengths of the two mixtures. The tensile strength of each mixture was less than the generally assumed tensile strength for conventional strength concrete, which is 10 percent of the unconfined compressive strength. Both concretes behaved similarly, but Cor-Tuf with steel fibers exhibited slightly greater strength with increased confining pressure, and Cor-Tuf without steel fibers displayed slightly greater compressibility.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2000년도 봄 학술발표회 논문집
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• pp.387-394
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• 2000

In the present study, laboratory pull-out tests with screw anchors are carried out to investigate behavior characteristics of underground structures applied uplift seepage forces. Small scaled pull-out tests in sand were conducted under saturated condition. And then, it was observed that the upward displacement as well as the pullout load varied with spacing of the anchor. Also, analyses have been performed with the aim of pointing out the effects of various parameters on the group effect of the screw anchors.

• 한국농공학회:학술대회논문집
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• 한국농공학회 1999년도 Proceedings of the 1999 Annual Conference The Korean Society of Agricutural Engineers
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• pp.556-561
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• 1999

The real strength evvelope for soils without cemetation goes through the origin and is curved. The Mohr -Coulomb failure criterion with the strength parameters c' and ø' from conventional tests overestimates the shear strength available at low normal stresses. The results of laboratory tests interpreted in terms of the Mohr-Coulomb failure criterion are not appropriate for evaluation of surficial slope stability , because the range of effective normal stresses in the field are not used in the laboratory tests.

• Toxicological Research
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• 제30권3호
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• pp.159-168
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• 2014

Pesticides have provided significant benefits including plant disease control and increased crop yields since people developed and utilized them. However, pesticide use is associated with many adverse effects, which necessitate precise toxicological tests and risk assessment. Most of these methods are based on animal studies, but considerations of animal welfare and ethics require the development of alternative methods for the evaluation of pesticide toxicity. Although the usage of laboratory animals is inevitable in scientific evaluation and alternative approaches have limitations in the whole coverage, continuous effort is necessary to minimize animal use and to develop reliable alternative tests for pesticide evaluation. This review discusses alternative approaches for pesticide toxicity tests and hazard evaluation that have been used in peer-reviewed reports and could be applied in future studies based on the critical animal research principles of reduction, replacement, and refinement.

• 대한한방내과학회지
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• 제39권2호
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• pp.176-183
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• 2018

Objectives: To observe the treatment progress of two patients diagnosed with alcoholic liver cirrhosis. Methods: We closely observed two patients with alcoholic liver cirrhosis who had visited the Department of Hepato-hemopoietic System, Kyung Hee University Korean Medicine Hospital in 2017. They were treated with Chungganhaeju-tang and auricular acupuncture, and we evaluated the changes in their general conditions and laboratory tests. Results: In the first case, the patient underwent continuous drinking despite the treatment, and the laboratory tests showed exacerbation. During the treatment, the patient stopped drinking for one week, and both clinical symptoms and laboratory tests were slightly improved. However, overall, there were no substantial improvements. In the second case, clinical symptoms and laboratory tests were markedly improved as the patient took herbal medicine and was treated with auricular acupuncture combined with abstinence from drinking. Conclusion: Two patients with alcoholic liver cirrhosis were observed with the treatment of Chungganhaeju-tang and auricular acupuncture. A patient with continuous drinking showed no improvements while a patient with abstinence from drinking showed substantial improvements in both clinical symptoms and laboratory tests.

• 의료ㆍ복지 건축 : 한국의료복지건축학회 논문집
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• 제26권1호
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• pp.73-84
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• 2020

Purpose: Though Korean healthcare services have been upgraded, infection and fire had been broken out in general hospitals. And higher concerns about quality assessment made it to clinical laboratory design guideline studies. So, this study investigates the facilities, equipment and personnel of laboratory medicine focusing on more than five hundred fifty bed hospital, and contributes to make guidelines for safety and efficiency in lab. Methods: Questionnaires to supervisor technologist and field surveys to medical laboratories in korean hospitals have been conducted for the data collection. 16 answers have been analysed statistically by MS Excel program. Results: Most of the sample tests such as hematology, clinical chemistry, immunology, transfusion, urinalysis, microbiology and molecular diagnosis are performed by more than 80% in large sized general hospital laboratory. In the test methods, automatic analyzers are used up to 80%, total laboratory automation up to 43% in clinical chemistry and immunology, and manual tests in all sorts of the test. There are placed in single lab or two and three labs above the ground, which are all in semi-open lab. There is some correlation with the number of specimens and the number of lab people depending on the number of hospital beds. Laboratory environment shows that work distance is good, but evacuation path width, visibility, separation of staff area from automatic analyzer, and equipment installations are needed to have more spaces and gears. Most of the infection controls are equipped with mechanical ventilation, air-conditioning, washbasin and wastewater separation, BSC installation and negative pressure lab room. Implications: Although the laboratory space area is calculated considering the number of hospital beds, type of tests and number of staff, hospital's expertise and the samples numbers per year should be taken into account in the planning of the hospital.

• 대한임상검사과학회지
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• 제37권2호
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• pp.111-117
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• 2005

The purpose of this study is to provide the basic guidelines of spatial and physical environment for the planning and design of clinical laboratory by analysing the extent of satisfaction of clinical laboratory scientists. The data for this analysis was gathered from March to May 2005 by the questionnaires of 208 clinical laboratory scientists who work in the 13 hospitals. All the collected data was analyzed by the SPSSWIN program. In this study, the satisfaction measurement tool was composed with 8 items and 5 score scale. The mean score of satisfaction for spatial and physical environment was 2.89 out of 5.0, "noise" was the lowest 2.40, "temperature and moisture of the lab." was 2.72, "lab. area, service area and administration area" was 2.77, "passageway space" was 2.94, circulation of workers was 2.94, "color of finish" was 3.19, "lighting of lab." was the highest 3.39. In conclusion, various factors, noise, temperature and moisture, clinical lab area, were evaluated to moderate dissatisfaction. Noise was especially the first serious problem in clinical lab. Considering the high growth of the number of tests, the planning of the clinical laboratory size should be considered not only to provide the optimal size but how it will correspond to the growth of the number of tests. Therefore the arrangement of each section need to be flexible in arrangement which is inevitable in expansion and reconstruction in the future.

• 한국지반환경공학회 논문집
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• 제14권1호
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• pp.61-68
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• 2013

본 연구에서는 지반보강재로서 폐타이어 사용에 따른 환경영향을 평가하기 위하여 실내실험 및 현장시험시공을 수행하였다. 실내실험을 통하여 폐타이어의 용출특성에 가장 큰 영향을 미치는 폐타이어의 입경과 배수조건을 변화시켜가며 유출수의 pH, 탁도, TOC, Zn 농도를 분석하였다. 또한, 현장시험시공을 통하여 폐타이어를 이용한 보강토 옹벽 시공 후 하부 집수정의 수질을 분석하였다. 입경에 따른 용출실험 결과 폐타이어 입경이 증가할수록 용출농도가 감소하는 것을 확인할 수 있었으며, 이는 비표면적의 차이 때문으로 판단된다. 배수조건에 따른 용출실험 결과 배수조건인 경우 시간이 경과할수록 용출농도가 감소하여 주변 환경에 큰 영향을 미치지 않을 것으로 판단되나, 비배수 조건인 경우 시간이 경과할수록 용출농도가 증가하는 현상을 발견할 수 있었다. 1년간의 현장모니터링 결과 폐타이어로 보강된 옹벽으로부터 발생되는 침출수는 전반적으로 용출농도가 높지 않은 것으로 나타났으며, 침출수 발생 초기에 농도가 증가하다가 이후 점점 감소하여 원수인 우수와 비슷해지는 경향을 나타내었다. 따라서 폐타이어를 지반보강재로 사용함에 따라 발생하는 환경적 영향은 무시할 수 있는 수준임을 알 수 있었다.