References
- Korea Ministry of Government Legislation. (2014) Agricultural chemicals regulation law. http://www.law.go.kr/lsInfoP.dolsiSeq=152000&efYd=20140318#0000.
- Korea Crop Protection Association. (2005) Safety of Pesticides- A Great Difference between Original Toxicity and Product Toxicity. Life and Pesticides, March, pp. 38-39.
- Russell, W.M.S., Burch, R.L. and Hume, C.W. (1959) The principles of humane experimental technique, Methuen, London.
- Gupta, K., Rispin, A., Stitzel, K., Coecke, S. and Harbell, J. (2005) Ensuring quality of in vitro alternative test methods: Issues and answers. Regul. Toxicol. Pharmacol., 43, 219-224. https://doi.org/10.1016/j.yrtph.2005.03.010
- Korea Ministry of Government Legislation. (2014) Animal Protection Law. http://www.law.go.kr/lsInfoP.do?lsiSeq=152326&efYd=20140324#0000.
- Notification No. 2013-21 of Rural Development Administration, Partly Amendment of Registration Standard of Pesticides and Technical Ingredients.
- Rural Development Administration. (2012) Press material-Reducing Animals on Evaluation Tests of Pesticides Safety.
- Beyond Pesticides, Bee protective : Pollinators and Pesticides, What the Science. http://www.beyondpesticides.org/pollinators/research.php.
- Johnson, R.M., Ellis, M.D., Mullin, C.A. and Frazier, M. (2010) Pesticides and honeybee toxicity-USA. Apidologie, 41, 312-331. https://doi.org/10.1051/apido/2010018
- OECD. (2001) Test No. 420: Acute Oral Toxicity - Fixed Dose Procedure. OECD, pp. 1-14.
- OECD. (2001) Test No. 423: Acute Oral toxicity - Acute Toxic Class Method. OECD, pp. 1-14.
- Park, K.H. (2011) Pesticides toxicity test system management and management condition. Annu. Meet. Korean Soc. Pestic. Sci., 30-37.
- European Commission. (2013) Legislation on pesticides-regulation. European, 283, 284.
- EPA. Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA). U.S. Environmental Protection Agency, http://www.epa.gov/oecaagct/lfra.html.
- EPA. (2012) Pesticide Program Dialogue Committee 21st Century Toxicology/New Integrated Testing Strategies Workgroup. U.S. Environmental Protection Agency.
- Hartung, T. (2011) From alternative methods to a new toxicology. Eur. J. Pharm. Biopharm., 77, 338-349. https://doi.org/10.1016/j.ejpb.2010.12.027
- Araujo, G.L.D., Campos, M.A.A., Valente, M.A.S., Silva, S.C.T., Franca, F.D., Chaves, M.M. and Tagliati, C.A. (2014) Alternative methods in toxicity testing: the current approach. Braz. J. Pharm. Sci., 50, 55-62. https://doi.org/10.1590/S1984-82502011000100005
- Pistl, J., Kovalkovi ova, N., Holovska, V., Legath, J. and Mikula, I. (2003) Determination of the immunotoxic potential of pesticides on functional activity of sheep leukocytes in vitro. Toxicology, 188, 73-81. https://doi.org/10.1016/S0300-483X(03)00046-5
- Andersen, H.R., Vinggaard, A.M., Rasmussen, T.H., Gjermandsen, I.M. and Bonefeld-Jorgensen, E.C. (2002) Effects of Currently Used Pesticides in Assays for Estrogenicity, Androgenicity, and Aromatase Activity In Vitro. Toxicol. Appl. Pharmacol., 179, 1-12. https://doi.org/10.1006/taap.2001.9347
-
Grunfeld, H.T. and Bonefeld-Jorgensen, E.C. (2004) Effect of in vitro estrogenic pesticides on human oestrogen receptor
${\alpha}$ and${\beta}$ mRNA levels. Toxicol. Lett., 151, 467-480. https://doi.org/10.1016/j.toxlet.2004.03.021 - Kojima, H., Katsura, E., Takeuchi, S., Niiyama, K. and Kobayashi, K. (2004) Screening for estrogen and androgen receptor activities in 200 pesticides by in vitro reporter gene assays using Chinese hamster ovary cells. Environ. Health Perspect., 112, 524-531.
- Vigfusson, N.V. and Vyse, E.R. (1980) The effect of the pesticides, Dexon, Captan and Roundup, on sister-chromatid exchanges in human lymphocytes in vitro. Mutat. Res., 79, 53-57. https://doi.org/10.1016/0165-1218(80)90147-0
- Jamil, K., Shaik, A.P., Mahboob, M. and Krishna, D. (2004) Effect of organophosphorus and organochlorine pesticides (monochrotophos, chlorpyriphos, dimethoate, and endosulfan) on human lymphocytes in-vitro. Drug Chem. Toxicol., 27, 133-144.
- Undeger, U. and Bacaran, N. (2005) Effects of pesticides on human peripheral lymphocytes in vitro: induction of DNA damage. Arch. Toxicol., 79, 169-176. https://doi.org/10.1007/s00204-004-0616-6
- Das, P.P., Shaik, A.P. and Jamil, K. (2007) Genotoxicity induced by pesticide mixtures: in-vitro studies on human peripheral blood lymphocytes. Toxicol. Ind. Health, 23, 449-458. https://doi.org/10.1177/0748233708089040
- Vinggaard, A.M., Hnida, C., Breinholt, V. and Larsen, J.C. (2000) Screening of selected pesticides for inhibition of CYP19 aromatase activity in vitro. Toxicol. In vitro, 14, 227-234. https://doi.org/10.1016/S0887-2333(00)00018-7
- Uggini, G.K. and Suresh, B. (2013) Genotoxic effects of two different classes of insecticide in developing chick embryos. Toxicol. Environ. Chem., 95, 992-1005. https://doi.org/10.1080/02772248.2013.828888
- Parent-Massin, D. and Thouvenot, D. (1993) In vitro study of pesticide hematotoxicity in human and rat progenitors. J. Pharmacol. Toxicol. Methods, 30, 203-207. https://doi.org/10.1016/1056-8719(93)90018-A
- Lotti, M. and Johnson, M.K. (1978) Neurotoxicity of organophosphorus pesticides: predictions can be based on in vitro studies with hen and human enzymes. Arch. Toxicol., 41, 215-221. https://doi.org/10.1007/BF00354093
- Radio, N.M. and Mundy, W.R. (2008) Developmental neurotoxicity testing in vitro : Models for assessing chemical effects on neurite outgrowth. Neurotoxicology, 29, 361-376. https://doi.org/10.1016/j.neuro.2008.02.011
- Kishore, A.S., Surekha, P.A., Sekhar, P.V., Srinivas, A. and Murthy, P.B. (2008) Hen egg chorioallantoic membrane bioassay: an in vitro alternative to draize eye irritation test for pesticide screening. Int. J. Toxicol., 27, 449-453. https://doi.org/10.1080/10915810802656996
- Triglia, D., Braa, S.S., Yonan, C. and Naughton, G.K. (1991) In vitro toxicity of various classes of test agents using the neutral red assay on a human three-dimensional physiologic skin model. In Vitro Cell. Dev. Biol. Anim., 27, 239-244. https://doi.org/10.1007/BF02630923
- Jeong, M.H., Kim, M.K., Park, S.J., You, A.S., Hong, S.S., Park, K.H. and Park, J.E. (2012) The application of alternative methods for skin irritation evaluation on pesticides. Korean J. Pestic. Sci., 16, 261-266. https://doi.org/10.7585/kjps.2012.16.3.261
- Seo, J.H., Park, J.W., Lee, S.K. and Kim, W.K. (2014) Application of neutral red uptake assay using EPC cells as an alternative to the fish acute toxicity test for pesticide. Korean J. Pestic. Sci., 18, 8-13. https://doi.org/10.7585/kjps.2014.18.1.8
- National Research Council of the National Academies. (2011) Guide for the Care and Use of Laboratory Animals (8th edition), the National academies Press, Washington D.C, pp. 1-8.
- Rudek, Z. and Ro ek, M. (1992) Induction of micronuclei in tadpoles of Rana temporaria and Xenopus laevis by the pyrethroid Fastac 10 EC. Mutat.Res., 298, 25-29. https://doi.org/10.1016/0165-1218(92)90025-U
- Embry, M.R., Belangerb, S.E., Braunbeckc, T.A., Galay-Burgosd, M., Haldere, M., Hintonf, D.E., Leonardg, M.A., Lillicrap, A., Norberg-Kingi, T. and Whalej, G. (2010) The fish embryo toxicity test as an animal alternative method in hazard and risk assessment and scientific research. Aquat. Toxicol., 97, 79-87. https://doi.org/10.1016/j.aquatox.2009.12.008
- Lagadic, L. and Caquet, T. (1998) Invertebrates in testing of environmental chemicals: Are they alternatives? Environ. Health Perspect., 106 Suppl 2, 593-611. https://doi.org/10.1289/ehp.98106593
- Bellas, J., Beiras, R., Marino-Balsa, J.C. and Fernandez, N. (2005) Toxicity of organic compounds to marine invertebrate embryos and larvae: a comparison between the sea urchin embryogenesis bioassay and alternative test species. Ecotoxicology, 14, 337-353. https://doi.org/10.1007/s10646-004-6370-y
- OECD. (2010) Guidance document on using cytotoxicity tests to estimate starting doses for acute oral systemic toxicity tests. OECD, France, pp. 1-54.
- McMahon, T., McCall, D., Matheson. J., Jacobs, A., Burns, T., Allen, D. and Stokes, W. (2011) Evaluation of the Murine Local Lymph Node Assay (LLNA) for Assessing the Allergic Contact Dermatitis Hazard Potential of Pesticide Formulations. Niceatm-Iccvam 8th World Congress Poster, USA, pp. 1
- Doosan encyclopedia. http://www.doopedia.co.kr, 'In silico'.
- Judson, R.S., Houck, K.A., Kavlock, R.J., Knudsen, T.B., Martin, M.T., Mortensen, H.M., Reif, D.M., Rotroff, D.M., Shah, I., Richard, A.M. and Dix, D.J. (2010) In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project. Environ. Health Perspect., 118, 485-492.
- Korea Food And Drug Administration. (2011) Press material - KFDA hosted international symposium on computational toxicity evaluation system. Korea.
- Hieter, P. and Boguski, M. (1997) Functional genomics: it's all how you read it. Science, 278, 601-602. https://doi.org/10.1126/science.278.5338.601
- Costa, L.G., Cole, T.B., Jarvik, G.P. and Furlong, C.E. (2003) Functional genomics of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism. Annu. Rev. Med., 54, 371-392. https://doi.org/10.1146/annurev.med.54.101601.152421
- Houck, K.A. and Kavlock, R.J. (2008) Understanding mechanisms of toxicity: Insights from drug discovery research. Toxicol. Appl. Pharmacol., 227, 163-178. https://doi.org/10.1016/j.taap.2007.10.022
- Krewski, D., Westphal, M., Al-Zoughool, M., Croteau, M.C. and Andersen, M.E. (2011) New directions in toxicity testing. Annu. Rev. Public Health, 32, 161-178. https://doi.org/10.1146/annurev-publhealth-031210-101153
- Wetmore, B.A., Wambaugh, J.F., Ferguson, S.S., Sochaski, M.A., Rotroff, D.M., Freeman, K., Clewell, H.J. 3rd., Dix, D.J., Andersen, M.E., Houck, K.A., Allen, B., Judson, R.S., Singh, R., Kavlock, R.J., Richard, A.M. and Thomas, R.S. (2012) Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment. Toxicol. Sci., 125, 157-174. https://doi.org/10.1093/toxsci/kfr254
- Hartung, T. (2010) Evidence-based toxicology-The toolbox of validation for the 21st century? ALTEX, 27, 253-263.
- Guzelian, P.S., Victoroff, M.S., Halmes, N.C., James, R.C. and Guzelian, C.P. (2005) Evidence-based toxicology: a comprehensive framework for causation. Hum. Exp. Toxicol., 24, 161-201. https://doi.org/10.1191/0960327105ht517oa
- Balls, M., Combes, R.D. and Bhogal, N. (2012) Physiologically-based pharmacokinetic (PBPK) models in toxicity testing and risk in New Technologies for Toxicity Testing (Lipscomb, J.C., Haddad, S., Poet, T., Krishnan, K.). Springer, New York, pp. 76-95.
- Timchalk, C., Nolan, R.J., Mendrala, A.L., Dittenber, D.A., Brzak, K.A. and Mattsson, J.L. (2002) A physiologically based pharmacokinetic and pharmacodynamic (PBPK/PD) model for the organophosphate insecticide chlorpyrifos in rats and humans. Toxicol. Sci., 66, 34-53. https://doi.org/10.1093/toxsci/66.1.34
- Poet, T.S., Kousba, A.A., Dennison, S.L. and Timchalk, C. (2004) Physiologically based pharmacokinetic/pharmacodynamic model for the organophosphorus pesticide diazinon. Neurotoxicology, 25, 1013-1030. https://doi.org/10.1016/j.neuro.2004.03.002
- van der Merwe, D., Brooks, J.D., Gehring, R., Baynes, R.E., Monteiro-Riviere, N.A. and Riviere, J.E. (2006) A physiologically based pharmacokinetic model of organophosphate dermal absorption. Toxicol. Sci., 89, 188-204. https://doi.org/10.1093/toxsci/kfj014
- Sharma, N.S., Jindal, R., Mitra, B., Lee, S., Li, L., Maguire, T.J., Schloss, R. and Yarmush, M.L. (2012) Perspectives on Non-Animal Alternatives for Assessing Sensitization Potential in Allergic Contact Dermatitis. Cell. Mol. Bioeng., 5, 52-72. https://doi.org/10.1007/s12195-011-0189-4
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