• 한국화재소방학회:학술대회논문집
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• 한국화재소방학회 2008년도 추계학술논문발표회 논문집
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• pp.513-517
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• 2008

• International Journal of Naval Architecture and Ocean Engineering
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• 제11권1호
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• pp.22-32
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• 2019

On offshore platforms, oil and gas leaks are apt to be the initial events of major accidents that may result in significant loss of life and property damage. To prevent accidents induced by leakage, it is vital to perform a case-specific and accurate risk assessment. This paper presents an integrated method of Ddynamic Qquantitative Rrisk Aassessment (DQRA)-using the Decision Making Trial and Evaluation Laboratory (DEMATEL)-Bayesian Network (BN)-for evaluation of the system vulnerabilities and prediction of the occurrence probabilities of accidents induced by leakage. In the method, three-level indicators are established to identify factors, events, and subsystems that may lead to leakage, fire, and explosion. The critical indicators that directly influence the evolution of risk are identified using DEMATEL. Then, a sequential model is developed to describe the escalation of initial events using an Event Tree (ET), which is converted into a BN to calculate the posterior probabilities of indicators. Using the newly introduced accident precursor data, the failure probabilities of safety barriers and basic factors, and the occurrence probabilities of different consequences can be updated using the BN. The proposed method overcomes the limitations of traditional methods that cannot effectively utilize the operational data of platforms. This work shows trends of accident risks over time and provides useful information for risk control of floating marine platforms.

• Journal of Interdisciplinary Genomics
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• 제3권1호
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• pp.7-12
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• 2021

Adverse drug reactions (ADRs) is a hypersensitivity reactions to specific medications, and remain a common and major problem in healthcare. ADRs suchc as drug-induced liver injury and life-threatening severe cutaneous adverse drug reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug rash with eosinophilia and systemic symptoms can be occurred by uncontrolled expansion of oligoclonal T cells according to genetically predisposing HLA. In this review, I summarized the alleles of HLA genes which have been proposed to have association with ADRs caused by different drugs.

• 한국환경농학회지
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• 제30권1호
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• pp.68-75
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• 2011

최근, 동물 및 인체용 의약품류는 환경 중 새로운 오염물질로 부각되고 있다. 특히, 우리나라는 동물용의약품에 대한 수의사 처방제 미정착, 집약적 축산환경, 최근의 대규모 지속적 동물 전염병의 발생, 단위 육류 생산량 증대를 위한 동물용의 약품의 남용, 축산분뇨의 해양투기 전면 금지 등 축산분야의 위협적 요소와 함께 환경 중 동물용의약품의 잔류성 문제가 향후 식품오염 및 항생제 내성 유발 등의 요인으로 확대 될 우려가 크다. 그러므로 동물용의약품의 주된 환경배출 매개인 분변을 통한 토양 잔류성 검토는 지하수 오염과 지하수 또는 분변 중 잔류량의 흡수, 이행과정을 통한 농경지 작물의 오염 예방을 위해서도 동물용의약품의 인허가 단계 중 토양 잔류성을 환경 위해성 평가자료로 검토하는 것은 중요한 의의를 갖는다. 본 연구는 VICH, OECD 등의 국제적 기구에서 그 동안 제안하였거나, 검토 중인 동물용의약품의 환경위해성 평가 가이드 라인과 오랫동안 우리나라, 미국, 유럽 등지에서 정착되어 온 농약의 토양 중 잔류성 시험법, 그리고 문헌을 토대로 기 수행한 동물용의약품의 토양잔류성 시험 결과를 바탕으로 하여 동물용의약품의 환경 중 위해성 평가를 위한 토양 잔류성 시험법 가이드라인을 제안하였다. 시험법 가이드라인은 크게 실내, 실외 시험 방법과 잔류소실기의 예측으로 구성되어 있으며, 농경지토양 내 분변을 통한 노출 경로를 주안으로 하여 우리나라 환경에 적합토록 구성하였다.

• Safety and Health at Work
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• 제2권2호
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• pp.105-121
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• 2011

Objectives: This paper presents the framework and protocol design for a construction industry risk management toolbox. The construction industry needs a comprehensive, systematic approach to assess and control occupational risks. These risks span several professional health and safety disciplines, emphasized by multiple international occupational research agenda projects including: falls, electrocution, noise, silica, welding fumes, and musculoskeletal disorders. Yet, the International Social Security Association says, "whereas progress has been made in safety and health, the construction industry is still a high risk sector." Methods: Small- and medium-sized enterprises (SMEs) employ about 80% of the world's construction workers. In recent years a strategy for qualitative occupational risk management, known as Control Banding (CB) has gained international attention as a simplified approach for reducing work-related risks. CB groups hazards into stratified risk 'bands', identifying commensurate controls to reduce the level of risk and promote worker health and safety. We review these qualitative solutions-based approaches and identify strengths and weaknesses toward designing a simplified CB 'toolbox' approach for use by SMEs in construction trades. Results: This toolbox design proposal includes international input on multidisciplinary approaches for performing a qualitative risk assessment determining a risk 'band' for a given project. Risk bands are used to identify the appropriate level of training to oversee construction work, leading to commensurate and appropriate control methods to perform the work safely. Conclusion: The Construction Toolbox presents a review-generated format to harness multiple solutions-based national programs and publications for controlling construction-related risks with simplified approaches across the occupational safety, health and hygiene professions.

• Journal of Microbiology and Biotechnology
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• 제14권2호
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• pp.390-394
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• 2004

The genetically modified glyphosate-tolerant soybean contains the following introduced DNA sequences: the EPSPS (5-enol-pyruvylshikimate-3-phosphate synthase) gene from Agrobacterium sp. strain CP4, the 35S promoter from the cauliflower mosaic virus, and the NOS terminator from Agrobacterium tumefaciens. In the present study, detection of these introduced DNAs was performed by amplification using the polymerase chain reaction (PCR). A multiplex PCR method was also applied to prevent false positive results. When primers for 35S promoter, nos3', CTP(chloroplast transit peptide), and CP4 EPSPS (EPSPS from Agrobacterium sp. CP4) were used, positive results were obtained in PCR reactions using DNA from genetically modified glyphosate-tolerant soybeans. There were no false positive results when using DNA from non-genetically modified soybeans. The CP4 EPSPS gene was detected when less than 125 pg glyphosate-tolerant soybean DNA was amplified. Lectin Lel and psb A were amplified from both non-genetically modified and genetically modified glyphosate-tolerant soybean DNA. Multiplex PCR was performed using different primer sets for actin Sacl, 35S promoter and CP4 EPSPS. The actin gene was detectable in both non-genetically modified and glyphosate-tolerant soybeans as a constant endogenous gene. Target DNAs for the 35S promoter, and CP4 EPSPS were detected in samples containing 0.01-0.1% glyphosate-tolerant soybean, although there were variations depending on primers by multiplex PCR. Soybean seeds from five plants of non-genetically modified soybean were co-cultivated for six months with those of genetically modified soybean, and they were analyzed by PCR. As a result, they were not positive for 35S promoter, nos3' or CP4 EPSPS. Therefore, these results suggest there was no natural crossing of genes between glyphosate-tolerant and non-genetically modified soybean during co-cultivation, which indicates that gene transfer between these plants is unlikely to occur in nature.

• ETRI Journal
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• 제37권5호
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• pp.1032-1043
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• 2015

ETRI's Co-Pilot project is aimed at the development of an automated vehicle that cooperates with a driver and interacts with other vehicles on the road while obeying traffic rules without collisions. This paper presents a core block within the Co-Pilot system; the block is named "Co-Pilot agent" and consists of several main modules, such as road map generation, decision-making, and trajectory generation. The road map generation builds road map data to provide enhanced and detailed map data. The decision-making, designed to serve situation assessment and behavior planning, evaluates a collision risk of traffic situations and determines maneuvers to follow a global path as well as to avoid collisions. The trajectory generation generates a trajectory to achieve the given maneuver by the decision-making module. The system is implemented in an open-source robot operating system to provide a reusable, hardware-independent software platform; it is then tested on a closed road with other vehicles in several scenarios similar to real road environments to verify that it works properly for cooperative driving with a driver and automated driving.

• 한국과학교육학회지
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• 제44권1호
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• pp.57-75
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• 2024

본 연구는 중등 과학교사들이 생각하는 과학기술 관련 위험교육 실태와 교육 요구를 조사하고자 총 366명의 중등 과학교사를 대상으로 설문조사를 실시하였다. 그 결과는 다음과 같다. 첫째, 과학기술로 인해 발생할 수 있는 위험을 위험지각, 위험평가, 위험관리 측면에서 교육해 본 적이 있는 교사보다 그렇지 않은 교사들이 더 많았다. 교사들이 지도해 본 위험으로는 지구온난화가 가장 많았으며, 지진, 인공지능, 교통사고가 그다음으로 많이 다루어졌다. 둘째, 교사들은 자신이 2022 개정 과학과 교육과정의 성취기준에 과학기술로 인해 발생할 수 있는 위험이 포함되어 있다는 것에 대한 이해가 부족하다고 인식하였으나 가르칠 준비는 되어 있다고 생각하였다. 셋째, 교사들은 위험관리, 위험평가보다 위험지각에 대한 자신들의 이해도가 높다고 인식하였다. 넷째, 교사들이 받은 위험에 대한 연수 경험은 매우 적었으며 위험지각에 비해 위험평가와 위험관리에 대한 연수 경험이 있는 교사의 수가 더 적었다. 교사들이 경험한 연수로는 실험실 안전교육이 가장 많았다. 다섯째, 교사들은 위험교육의 10가지 목표에 대한 자신들의 역량이 높지 않다고 인식하고 있었다. 중학교 교사, 통합과학교육 전공 교사의 경우 상대적으로 자신들의 역량을 높이 평가하였다. 여섯째, 다수의 교사들이 학교 과학교육에서 위험을 다루는 것에 대해 중요하게 생각하고 있었다. 또한 정보 활용, 의사 결정 역량, 대중매체의 영향평가 순으로 중요하다고 생각하였으며, 실천역량, 정보활용, 위험특성영향평가 순으로 교육이 시급하다고 응답하였다. 일곱째, 위험교육의 10가지 목표별 교육요구도 우선순위를 도출한 결과, 실천역량, 위험특성의 영향평가, 위험평가방법에 대한 평가가 각각 1, 2, 3위로 나타났다.

• 대한불안의학회지
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• 제15권1호
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• pp.29-34
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• 2019

Objective : To determine predictors of posttraumatic stress disorder (PTSD) symptoms in burn injured patients and evaluate factors for identifying high risk group of PTSD. Methods : This study examined sixty one patients aged in the range of 19-65 years with burn injuries. All subjects completed self-assessment inventories about PTSD (The PTSD Check List for DSM-5. PCL-5), depression (Patient Health Questionnaire-9, PHQ-9), embitterment (Posttraumatic embitterment disorder self-rating scale, PTED scale) and meaning of life (Meaning in Life Questionnaire, MLQ). Stepwise multiple regression and ROC curve analysis were the tools used for analysis. Results : The results revealed higher depression, embitterment and lower presence of meaning in life predicted severe PTSD symptoms. ROC analysis indicated PTED scale and PHQ-9 were useful for discriminating high risk group of PTSD. Conclusion : The present study established that the need to consider embitterment, depression and meaning of life for alleviation and prevention of PTSD symptoms in burn patients.

• Safety and Health at Work
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• 제11권4호
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• pp.431-442
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• 2020

Background: Psychosocial risks are increasingly a type of risk analyzed in organizations beyond chemical, physical, and biological risks. To this type of risk, a greater attention has been given following the update of ISO 9001: 2015, more precisely the requirement 7.1.4 for the process operation environment. The update of this normative reference was intended to approximate OHSAS 18001: 2007 reference updated in 2018 with the publication of ISO 45001. Thus, the organizations are increasingly committed to achieving and demonstrating good occupational health and safety performance. Methods: The aim of this study was to characterize the psychosocial risks in a cryopreservation laboratory and to develop a predictive model for psychosocial risk management. The methodology followed to collect the information was the inquiry by questionnaire that was applied to a sample comprising 200 employees. Results: The results show that most of the respondents are aware of the psychosocial risks, identifying interpersonal relationships and emotional feelings as the main factors that lead to this type of risks. Furthermore, terms such as lack of resources, working hours, lab equipment, stress, and precariousness show strong correlation with psychosocial risks. The model presented in this study, based on artificial neural networks, exhibited good performance in the prediction of the psychosocial risks. Conclusion: This work presents the development of an intelligent system that allows identifying the weaknesses of the organization and contributing to the enhancement of the psychosocial risks management.