• 제목/요약/키워드: kit evaluation

검색결과 216건 처리시간 0.027초

Alpha feto protein(AFP)검사 키트의 유효성 평가실험 (Evaluation of the Kit's Efficiency of Alpha Fetoprotein (AFP) Test)

  • 조현수;노경운;유태민
    • 핵의학기술
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    • 제22권2호
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    • pp.101-104
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    • 2018
  • Purpose Alpha fetoprotein(AFP) is a fetal serum protein that increases in germ cell tumors derived from liver cancer or egg yolk. AFP test has been used for screening of liver cancer, determination of tumor stage, determination of therapeutic effect, and fetal congenital malformations. The purpose of this study was to compare the results of the four kits, identify the advantages and disadvantages of each kit, and select the appropriate kits for our laboratory. Materials and Methods Blood samples were obtained from 89 patients attending the Seoul national university hospital. Experiments were carried out in accordance with manufacturer's instructions of four companies(A, B, C, D). The precision, recovery, linearity, and sensitivity test were performed for each kit. Results In case of the precision within the measurement, the CV value of the C kit was less than 5% at the low, middle, and high concentrations. The A, B and D kit's the CV value was less than 5% at the concentrations except the low concentration. The recovery rates of the A, B, C, and D kits were $100{\pm}15%$, $100{\pm}30%$, $100{\pm}16%$ and $100{\pm}14%$, respectively. All kits showed good linearity. Sensitivity was measured as 0.5 IU/mL for A, 0.4 IU/mL for B, 0.98 IU/mL for C, and 0.3 IU/mL for D. Conclusion The CV values of the four kits were within 10%, and the correlation coefficients were close to 1 for $R^2=0.978$, $R^2=0.992$ and $R^2=0.8957$. As a result, they are clinically available. Therefore, each laboratory should select the appropriate kit for their experiment's environment.

근골격계질환 예방을 위한 인간공학적 작업시스템 평가킷의 표준화 (Standardization of the Ergonomics Kit for Evaluating Musculoskeletal Hazards in the Work System)

  • 김상호;이홍태
    • 대한안전경영과학회지
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    • 제7권1호
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    • pp.57-76
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    • 2005
  • A standardized ergonomics kit is suggested to evaluate and reduce musculoskeletal hazards that yield large socioeconomic burdens in the work system. This kit comprises basic and detailed analysis tools with proper tool selection rules. The basic tool includes a checklist for various risk factors to screen potentially hazardous jobs among manual works. Selective detailed analysis tools can then be applied to the screened job lists for more quantitative and precise evaluation. The tool selection rules are devised for using the basic and detailed analysis tools in a mutually supplemental way. To validate the standardized ergonomics kit, it was applied to evaluate jobs related to the musculoskeletal hazards in a paper-making industry. Among 101 manual jobs investigated, 44 potential hazardous jobs were screened during basic investigation phase and finally 16 hazardous jobs were identified by the detailed analysis phase. The result provided fairly promising ideas of ergonomic interventions for the hazardous jobs.

Hepatitis B Surface Antigen을 신속히 검출하기 위한 Immunochromatographic Assay kit의 성능 평가 (The Evaluation of Immunochromatographic Assay kit for Rapid Detection of Hepatitis B Surface Antigen)

  • 신형순;김영봉;신정우;김창규;이왕식;김한겸;신광순
    • 대한바이러스학회지
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    • 제27권2호
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    • pp.137-141
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    • 1997
  • We evaluated Immunochromatographic assay kit to screen HBsAg in human serum. When the reference HBsAg was applyed to ICA, HA and EIA kits, the limit of detection for HBsAg were found out to be 4, 2 and 0.25 ng/ml respectively. But ICA kit required 5 minutes to read the result whereas HA and EIA kit more than one hour. The sensitivity was 97% (29 of 30 samples) and the specificity 100% (45 samples) compared with conventional EIA. The ICA kit needs no instrument or machine to perform the test contrary to the conventional methods. Therefore, this rapid and sensitive ICA kit can be used for HBsAg-screening, especially in the emergency room and in the scene of the accident.

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WebKit 모바일 웹 브라우저의 성능 향상을 위한 기법 연구 (A Study of High Performance WebKit Mobile Web Browser)

  • 김정길
    • 한국위성정보통신학회논문지
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    • 제7권1호
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    • pp.48-52
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    • 2012
  • 스마트폰의 급속한 보급 확산에 따라 모바일 기기에서 웹 브라우저는 주요한 기능으로 자리 잡고 있으며 사용자는 모바일 기기에서 PC 수준의 고속화된 성능을 기대하는 현실이다. 웹키트(WebKit)는 구글의 안드로이드(Android) 플랫폼에 사용되고 있는 웹 브라우저를 만드는 데 기반을 제공하는 오픈 소스 응용 프로그램 프레임워크이다. 본 논문에서는 WebKit 라이브러리의 연산의 병렬처리를 통한 성능 향상 기법을 제안하였다. 제안된 병렬처리 기법은 JPEG 라이브러리에 적용되었으며, 성능 검증은 PC 기반의 실험을 통하여 이기종 컴퓨팅 기반의 모바일 임베디드 시스템 환경에서의 예측 방법을 사용하였다. 실험 결과는 제안된 병렬화 기법이 이기종 컴퓨팅 환경의 모바일 임베디드 기기로의 적용을 통한 성능 향상 가능성을 보여주었다.

수중형 자율운항 해양로봇키트 개발 (Development of Underwater-type Autonomous Marine Robot-kit)

  • 김현식;강형주;함연재;박승수
    • 한국지능시스템학회논문지
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    • 제22권3호
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    • pp.312-318
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    • 2012
  • 최근에는, 극한 분야에서 해양로봇의 필요성이 제기되고 있으나, 그 기반이 매우 부족한 실정이다. 다행히 로봇경진대회가 활성화되고 로봇교육에 대한 수요가 증가하는 추세이므로, 해양로봇키트의 개발/보급을 통하여 해양로봇 연구개발/산업화 기반을 마련하고 전문인력을 양성하는 것이 바람직하다. 그런데, 기존에는 수중이동 및 표적 탐지/회피가 가능한 해양로봇경진대회용 수중형 자율운항 해양로봇키트가 없었다. 이 문제를 해결하기 위해서 수중이동성, 수중방수성 및 무게조절성이 우수한 보급형 해양로봇키트가 개발되었다. 개발된 키트의 성능 검증을 위해서 Surge, Pitch, Yaw, 장애물회피 등의 시험 평가가 수행되었다. 시험평가 결과는 개발된 키트의 실제 적용 가능성을 보여준다.

Accuracy of c-KIT in lung cancer prognosis; a systematic review protocol" instead of c-KIT Expression in Lung Cancer Prognostic Evaluation - a Systematic Review Protocol

  • Roudi, Raheleh;Kalantari, Elham;Keshtkar, Abbas;Madjd, Zahra
    • Asian Pacific Journal of Cancer Prevention
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    • 제17권2호
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    • pp.863-866
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    • 2016
  • Background: Extensive efforts have been made to investigate c-KIT expression in lung cancer specimens and its correlation with clinical outcomes, but the issue remains unresolved. Thus, this study will be conducted to clarify the prognostic value of c-KIT expression in lung cancer patients. Materials and Methods: We will search Pubmed, SCOPUS, and ISI web of sciences with no restriction of language. Studies with any design (except case reports or case series) evaluating correlations of c-KIT expression with survival or outcome in patients with lung cancer will be included. The outcome measures will include all types of survival indexes, including overall survival rate and disease free survival using Kaplan-Meier analysis and hazard ratios. Study selection and data extraction will be performed by two independent researchers. Quality assessment (assessment of risk of bias) and data synthesis will be implemented using Stata software version 11.1. Results: No ethical issues are predicted. These findings will be published in a peer-reviewed journal and presented at national and international conferences. Conclusions: This systematic review protocol is registered in the PROSPERO International Prospective Register of Systematic Reviews, registration number = CRD42015023391.

Assessment of dentists' subjective satisfaction with a newly developed device for maxillary sinus membrane elevation by the crestal approach

  • Kim, Young-Kyun;Cho, Yong-Seok;Yun, Pil-Young
    • Journal of Periodontal and Implant Science
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    • 제43권6호
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    • pp.308-314
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    • 2013
  • Purpose: The purposes of this study were to assess the dentists' subjective satisfaction with the crestal approach sinus (CAS) kit, a device for maxillary sinus membrane elevation by the crestal approach using a special drilling system and hydraulic pressure, and to summarize the subjective satisfaction of dental implants placed after a sinus lift procedure with the CAS kit. Methods: Thirty dental clinicians who had experience with dental implant placement after a sinus lift procedure with the CAS kit from June 2010 to May 2012 were included in this study. The questionnaire for the evaluation of the dentists' subjective satisfaction with the CAS kit was sent to the respondents and returned. The questionnaire was composed of two main parts. The first part was related to the sinus membrane perforation rate. The second part was related to the dentists' subjective satisfaction with the CAS kit. Results: A total of 28 dentists answered the questionnaire. Among 924 implant cases, sinus membrane perforation occurred in 38 cases (4.1%). Among the 28 dentists, 26 dentists (92.9%) were satisfied or very satisfied with the CAS kit. In particular, 24 dentists (85.7%) reported that safety, cutting performance, and user-friendliness of the CAS drill were advantages of the CAS kit. However, 7 dentists (25%) did not routinely use the hydraulic lifter for sinus membrane elevation. Conclusions: From the survey, it was shown that the respondents were generally satisfied with the CAS kit and that the cutting performance and safety of the drill component were considered strengths of the CAS kit.

Evaluation of Two ELISA and Two Indirect Hemagglutination Tests for Serodiagnosis of Pulmonary Hydatid Disease

  • Eris, Fatma Nur;Akisu, Ciler;Aksoy, Umit
    • Parasites, Hosts and Diseases
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    • 제47권4호
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    • pp.427-429
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    • 2009
  • To establish a definite diagnosis for pulmonary hydatid disease, combination of radiology and serology is useful. In this study, 19 preoperative sera from patients with surgically confirmed pulmonary hydatidosis, 40 sera from patients with other parasitosis and pulmonary diseases, and 20 sera from healthy donors were evaluated using 4 different serological tests, i.e., the commercial ELISA (ELISA-kit) test, the ELISA (ELISA-lab) test prepared in our laboratory, the commercial indirect hemagglutination assay kit (IHA-kit) test, and the IHA test using sensitized sheep red blood cells with tannic acid (IHA-TA). The ELISA-kit was the most sensitive (84.2%) and the most specific test (100.0%). The ELISA-kit also demonstrated the highest positive (100.0%) and negative (95.2%) predictive values. The sensitivity of the ELISA-lab test, that we prepared, was found to be 73.6%, whereas the IHA-kit test and the IHA-TA test were found to be 73.6% and 68.4%, respectively. The specificity of these tests was 96.6%, 98.3%, and 83.3%, respectively. When all 4 tests were assessed together, it was found that the sensitivity had risen to 94.7%. When the ELISA-kit was assessed with the IHA-kit and IHA-TA together, it was found that the sensitivity was 89.5% and 84.2%, respectively. Likewise, the combination of the ELISA-lab and IHA-kit or IHA-TA allowed us to achieve a sensitivity of 84.2% in cases of pulmonary echinococcosis. In conclusion, the diagnosis would be imminent if least 2 tests were applied together.

한우 인공수정에서 수정적기 진단키트 활용이 수태율에 미치는 영향 (Effects of Optimal Heat Detection Kit on Fertility after Artificial Insemination (AI) in Hanwoo (Korean Native cattle))

  • 최선호;진현주
    • 한국수정란이식학회지
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    • 제32권3호
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    • pp.153-157
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    • 2017
  • This study was conducted to investigate the optimal artificial insemination (AI) time with diagnostic kit at ovulation time. We already applied the patent about the protein in the cow heat mucose in external reproductive tract. And we would examine the accuracy for detection of cow heat by the kit produced with the protein. Evaluation of optimal heat detection was tried two time at 12 hrs and 24 hrs after the heat. And then, AI service also performed two times with no relation to the results of heat diagnosis by heat detection kit and pregnancy rates were checked with rectal palpation on $60^{th}$ day after AI. Heat diagnostic results by kit in natural heat after 12 hrs in Hanwoo cows were showed 31.3~75.0% on positive in first heat detection and 33.3~100.0% on positve in second heat detection. In the $1^{st}$ positive results were significant different (p<0.05), but $2^{nd}$ positive were not. The results of heat detection showed different result on regional influence and individual cow effects. The pregnancy rates of first trial of heat detection were showed 34.4~78.7% on positive and 21.3~68.8% on negative after the diagnosis by heat detection kit. And the pregnancy rates of next trial of heat detection were showed 33.3~85.7% on positive and 14.3~66.6% on negative after the heat diagnosis. Both positive results of first trial and next trial also were showed significant different (p<0.05), but negative results were not. In positive result, first trial of total pregnancy rates was higher than the next trial of pregnancy, but there showed opposite results on negative results. In conclusion, the optimal heat detection kit is suitable to ordinary Hanwoo cows and it suggested that we have to improve the kit's accuracy by detecting the materials like proteins related optimal AI time.