• Title/Summary/Keyword: isopropyl

Search Result 434, Processing Time 0.026 seconds

Effects of Isopropyl Alcohol Infusions on the Ruminating Behavior of Goats

  • Asato, N.;Hirata, T.;Hirayama, T.;Onodera, R.;Shinjo, A.;Oshiro, S.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.14 no.8
    • /
    • pp.1085-1089
    • /
    • 2001
  • Metabolites, such as isopropyl alcohol (IPA) produced by rumen fermentation, were intravenously infused into a jugular vein of goats during feeding to explore the mechanism and roles of IPA in ruminating behavior (number of boli and ruminating time). Three female goats were confined in metabolism cages with a stanchion, The ruminating behavior measured by the number of ruminations, ruminating time, number of remastications, and remasticating time decreased (p<0,05) with intravenous IPA infusion. The IPA concentrations and VFA concentrations increased in the blood circulation. Our data suggest that sensitive receptors of rumination to IPA are more likely to be in an area such as the brain stem where they can respond to blood metabolite levels.

Effects of Intraruminal Isopropyl Alcohol Infusions on the Ruminating Behavior of Goats

  • Asato, N.;Hirata, T.;Hirayama, T.;Onodera, R.;Shinjo, A.;Oshiro, S.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.15 no.8
    • /
    • pp.1134-1138
    • /
    • 2002
  • Isopropyl alcohol (IPA), produced from acetone by rumen bacterial action, was infused into the rumen of three female goats kept in a climatically controlled experimental room during feeding to investigate the mechanism and roles of IPA in ruminating behavior (number of boli and ruminating time). The ruminating behavior measured by the number of boli, ruminating time, number of remastications, and remasticating time increased (p<0.05) with intraruminal IPA infusion. The concentrations of IPA and acetone in the rumen and the plasma significantly increased (p<0.05) during intraruminal IPA infusion. These data suggest that rumination receptors sensitive to IPA and acetone may be in an area such as the rumen epithelium and the brain stem where they can respond to metabolite levels.

Studies on Lactobacillus Virulent Phage in Plantdrainage (공장배수계에 존재하는 유산간균 Virulent Phage에 관한 연구)

  • 강국희;백영진;강영찬;김기원
    • Microbiology and Biotechnology Letters
    • /
    • v.5 no.1
    • /
    • pp.13-17
    • /
    • 1977
  • We isolated lactobacillus phage hosting L. casei strains, and examined distribution of the phages and resistance to the sanitary reagent treatment in drainages fo Korea plant. 1) There were Type 1, 11, 111, and 1v of the phage J$_1$in plantdrainages and the order of distribution was Type 1v>Type 11>Type 1>$^1$Type 111. 2) All the phages in plantdrainages were completely removed by spreading the invert soap. 3) Sodium hypochloride, invert soap and dresol were most effective sanitary reagents, and isopropyl alcohol and ethyl alcohol were sanitary reagents.

  • PDF

Fabrication of High Efficiency Silver Halide Holograms by Reversal Bleaching Process (반전표백 방법에 의한 고효율 은염건판 홀로그램 제작)

  • 백성훈;홍석경;김철중
    • Korean Journal of Optics and Photonics
    • /
    • v.2 no.2
    • /
    • pp.89-95
    • /
    • 1991
  • High diffraction efficiency holographic gratings in silver halide emulsion were fabricated by using reversal bleaching process. The diffraction efficiencies of gratings were improved greatly by applying rapid drying procedure with isopropyl alcohol after bleaching with optimized developers. The dependency of diffraction efficiencies on the different groups of developers, the concentration of bleaching solutions, and the drying methods are investigated experimentally and the results were analyzed theoretically. Same as usual reversal bleaching process, the fabricated gratings showed very low scttering compared to those made by conventional bleach process. The maximum diffraction efficiency was 88%.

  • PDF

Synthesis of 4-(2-thiazolyloxy)phenylalkanoic Acids As An An-tiinflammatory Agent

  • Choi, Hong-Dae;Shin, Sang-Hoon;Son, Byeng-Wha
    • Archives of Pharmacal Research
    • /
    • v.19 no.2
    • /
    • pp.148-152
    • /
    • 1996
  • The efficient synthesis of 4-(2-thiazolyloxy)phenylalkanoic acids (10a-c), which are a potent antiinflammatory agent, was achieved in 5-6 steps starting from isopropoxybenzene and methyl $\alpha-chloro-\alpha-(methylthio)acetate (1)$. The key intermediate (4) was prepared by Friedel-Crafts reaction of isopropoxybenzene with (1) followed by desulfurization and the removal of isopropyl protector. Methyl 4-hydroxyphenylalkanoates (6, 8) were similarly obtained from alkylation of (3) and deprotection.

  • PDF

Inhibition of MMP-1 Expression and Collagen Synthesis Activity of Ultrasonication Processed Ginseng Flower Buds Extract (초음파 처리 인삼화뢰 추출물의 콜라겐 합성작용 및 MMP-1 발현저해)

  • Kim, Shin Jung;Nam, Yun Min;Kim, Yong Min;Ko, Sung Kwon
    • Korean Journal of Pharmacognosy
    • /
    • v.46 no.2
    • /
    • pp.154-159
    • /
    • 2015
  • This study was to evaluate the effect of isopropyl alcohol fraction of ultrasonication processed ginseng flower buds(GFB-IF) on the collagen synthesis activity and inhibition of MMP-1 suppression in UV-irradiated human dermal fibroblasts. The higher contents of ginsenoside Rg2(8.234%), Rh1(5.749%), F4(3.881%) in isopropyl alcohol fraction of ginseng flower buds obtained by ultrasonication process at 600W(100℃) for 16 hours. GFB-IF had collagen synthesis effect. GFB-IF induced a significant dose-dependent decrease in the expression for MMP-1 protein. These results suggest that GFB-IF is a potential candidate for the prevention and treatment of wrinkle improving.

Chiral Recognition in Gas chromatographic Resolution of Amino -$^1H\;and^{13}C$ Nuclear magnetic resonance studies of hydrogen bonding in dinmide chiral stationary phases-

  • Park, Man-Ki;Yang, Jeong-Sun;Sohn, Dong-Hwan;Lee, Mi-Young
    • Archives of Pharmacal Research
    • /
    • v.12 no.1
    • /
    • pp.58-61
    • /
    • 1989
  • Studies of selectivity of hydrogen bond formation in chiral solute-solvent systems have been performed by $^1H\;and\;^{13}C$ nuclear magnetic resonance techniques. These data are correlated with the results of gas chromatographic investigations of the same systems. Interactions between the optically active solvent(N-(N-benzoyl-L-amino acid)-anilide) and optically active solute (N-trifluoroacetyl -L-alanyl isopropyl ester) were examined. NMR evidence indicated that hydrogen bonding interaction occurred between two N-H portion and on peptidyl carbonyl portion in stationary phase and solute molecule on three points. The association constants of solvent-solute interaction were calculated and the structure of the diastereomeric association complex between N-(N-benzoyl-L-valyl)-anilide and N-TFA-L-alanyl isopropyl ester was proposed.

  • PDF

Synthesis and Properties of Organosilicon Polymers Containing 3,4-Benzo-1-silacyclopentene Derivatives

  • 박영태;박상욱;김호창;이광
    • Bulletin of the Korean Chemical Society
    • /
    • v.19 no.3
    • /
    • pp.328-332
    • /
    • 1998
  • Anionic ring-opening polymerization of 3,4-[(dimethylsilyl)isopropyl]benzo-1,1-dimethyl-1-silacyclopentene in the presence of n-butyllithium and HMPA in THF at - 78 ℃ afforded poly[3,4-(dimethylsilylisopropyl)benzo-1,1-dimethyl-1-silapentene]. The characteristic Si-H stretching frequency in the IR is observed at 2100 cm-1. The polycarbosilane has been modified by chloroplatinic acid catalyzed addition of styrene to the polycarbosilane SiH units. Molecular weights and thermal properties of the polymers were compared. The sol-gel polymerization of 3,4-[(dimethoxysilyl)isopropyl]benzo-1,1-dimethoxy-1-silacyclopentene in the presence of aqueous HCl or NaOH in THF resulted in a cross-linked polysiloxane. The xerogel has a low surface area of 13-14 m2/g and is stable up to about 400 ℃ with only 5% weight loss under a nitrogen atmosphere.

Influence of 3-(N-methyl-N-X(sub.)phenylaminooxoacetyl) group on the herbicidal activity of Imazethapyr derivatives (Imazethapyr 유도체의 제초활성에 미치는 3-(N-methyl-N-(X)-치환-phenylaminooxoacetyl) group의 영향)

  • Sung, N.D.;Kim, H.J.;Chang, H.S.;Kim, D.W.
    • Applied Biological Chemistry
    • /
    • v.36 no.5
    • /
    • pp.381-386
    • /
    • 1993
  • New twenty five Imazethapyr derivatives, [2-(4-isopropyl-4-methyl-5-oxo-2-imidazolin -2-yl)-3-(N-methyl-N-X(sub.)-phenylaminooxoacetyl)-5-methylpyridine] were synthesized. and The quantitative structure activity relationships (QSARs) between their post-emergence herbicidal activity$(pI_{50})$ values in vivo against Barnyard grass (Echinochloa crus-galli) and physicochemical parameters of substituents(X) of 3-(N-methyl-N-X(sub.)-phenylaminooxoacetyl) group have been studied. From the basis on the findings, in case of post-emergence, the activities were dependent on the steric constant$(E_s<0)$ and electron donating $(\sigma<0)$ effect by subsitituents(X) of 3-(N-methyl-N-X(sub.)phenylaminooxoacetyl) group. Therefore, The most effective compound,15 (4-t-butyl group) and 20 (3,5-dimethyl group) were examined in this study. And the conditions on the compounds predicted to show higher herbicidal activity were also discussed.

  • PDF