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http://dx.doi.org/10.5713/ajas.2002.1134

Effects of Intraruminal Isopropyl Alcohol Infusions on the Ruminating Behavior of Goats  

Asato, N. (Faculty of Agriculture, University of the Ryukyus)
Hirata, T. (Tokyo University of Agriculture and Technology)
Hirayama, T. (Faculty of Agriculture, University of the Ryukyus)
Onodera, R. (Faculty of Agriculture, Miyazaki University)
Shinjo, A. (Faculty of Agriculture, University of the Ryukyus)
Oshiro, S. (Faculty of Agriculture, University of the Ryukyus)
Publication Information
Asian-Australasian Journal of Animal Sciences / v.15, no.8, 2002 , pp. 1134-1138 More about this Journal
Abstract
Isopropyl alcohol (IPA), produced from acetone by rumen bacterial action, was infused into the rumen of three female goats kept in a climatically controlled experimental room during feeding to investigate the mechanism and roles of IPA in ruminating behavior (number of boli and ruminating time). The ruminating behavior measured by the number of boli, ruminating time, number of remastications, and remasticating time increased (p<0.05) with intraruminal IPA infusion. The concentrations of IPA and acetone in the rumen and the plasma significantly increased (p<0.05) during intraruminal IPA infusion. These data suggest that rumination receptors sensitive to IPA and acetone may be in an area such as the rumen epithelium and the brain stem where they can respond to metabolite levels.
Keywords
IPA; Acetone; Rumination; Intraruminal Infusion; Goats;
Citations & Related Records

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1 Forbes, J. M. and J. P. Barrio. 1992. Abdominal chemo-and mechanosensitivity in ruminants and its role in the control of food intake. Exp. Physiol. 77(1):27-50.   DOI
2 Luick, J. R., A. L. Black, M. G. Simesen, M. Kametaka and D. S. Kronfeld. 1967. Acetone metabolism in normal and ketotic cows. J. Dairy Sci. 50:544-549.   DOI   ScienceOn
3 Oshiro, S. and T. Katayama. 1987. Effects of physiological responses of goats. West JPN. J. Anim. Sci. 30:30-36.
4 Oshiro, S., O. M. Mamun, S. Wadud, R. Onodera, T. Hirayama, M. Hirakawa and H. Higoshi. 2000. Effects of fatty acids and acetone infusions on the ruminating behavior of goats. Small Ruminant Research 35:117-122.   DOI   ScienceOn
5 Rudney, H. 1954. Propanediol phosphate as a possible intermediate in the metabolism of acetone. J. Biol. Chem. 210:361-371.   PUBMED
6 Thin, C., H. Paver and A. Robertson. 1959. The metabolism of ketone bodies in the ruminant. J. Comp. Path. 69:45-64.   DOI
7 Trinder, P. J. 1969. Determination of blood glucose using an oxidase-peroxidase system with a non-carcinogenic chromogen. J. Cli. Path. 22:158-161.   DOI
8 Kawamura, T., N. Asato and S. Oshiro. 1999. Effects of intraruminal acetone infusions on ruminating behavior of goats. Anim. Sci. Technol. (Jpn.). Proceeding, Ⅵ-25. p. 97.
9 Lahman, S., M. Potvin, K. Schrander and I. Marino. 1980. Studies on inhalation toxicity of 2-propanol. Drug Chem. Toxicol. 3:343-360.   DOI
10 Forbes, J. M. 1986. The voluntary food intake of farm animals. Butter Worths, London, pp. 33-51.
11 Black, A. L., J. R. Luick, S. L. Lee and K. Knox. 1972. Glucogenic pathway for acetone metabolism in the lactating cow. Am. J. Physiol. 222:1575-1580.
12 Duncombe, W. G. 1964. The colorimetric micro-determination of non-esterized fatty acids in plasma. Cli. Chim. Acta. 9:122-193.   DOI   ScienceOn
13 Nordmann, R., C. Ribiere, H. Rouach, B. Beauge, Y. Giudicelli and J. Nordmann. 1973. Metabolic pathway involved in the oxidation of isopropanol into acetone by the intact rat. Life Sci. 13:919-932.   DOI   ScienceOn
14 Oshiro, S., T. Oikawa and T. Katayama. 1988. Effects of light, dark and feeding method on the circadian rhythm of ruminating and masticating behavior in goats. West JPN. J. Anim. Sci. 31:23-31.
15 Oshiro, S. 1985. Effects of forced feeding on physiological responses in goats. Anim. Sci. Technol. (Jpn.). 56:312-317.
16 Simkins, K. L. Jr., J. W. Suttie and B. R. J. Baumgrandt. 1967. Regulation of food intake in ruminants. 4. Effect of acetate, propionate, butyrate, and glucose on voluntary food intake in dairy cattle. J. Dairy Sci. 48:1635-1642.   DOI
17 Asato, N., T. Hirata, T. Katayama, R. Onodera, A. Shinjo and S. Oshiro. 2001. Effects of isopropyl alcohol infusions on the ruminating behavior of goats. Asian-Aust. J. Anim. Sci. 14(7):1085-1089.   DOI
18 Baile, C. A. and J. Mayer. 1968. Effects of intravenous versus intraruminal injections of acetate on feed intake of goats. J. Dairy Sci. 51:1490-1494.   DOI   ScienceOn
19 Montgomery, M. J. and B. R. Baumgardt. 1965. Regulation of food intake in ruminants. 1. Pelleted rations varying in energy concentration. J. Dairy Sci. 5:569-574.   DOI   ScienceOn
20 Ulyatt, M. J. 1965. The effects of intra-ruminal infusion of volatile fatty acid on food intake of sheep. N. Z. J. Agric. Res. 8:397-408.   DOI
21 Oshiro, S. and Z. Koja. 1987. Effects of feed length on feeding and ruminating behavior in Japanese Black Cattle. Sci. Bull. Coll. Agric. Univ. Ryukyus 34:59-65.
22 Snedecor, G. M. and M. G. Cochran. 1989. Statistical Methods (8th Ed.). The Iowa State University Press.
23 Thin, C. and A. Robertson. 1953. Biochemical aspects of ruminant ketosis. J. Comp. Path. 63:184-194.   DOI
24 Anderson, B. 1951. The effects of localization of electrical stimulation of certain parts of brain stem in sheep and goats. Acta. Physiol. Scand. 23:8-23.   DOI   ScienceOn
25 Bruss, M. L. and M. J. Lopez. 2000. Mixed ruminal microbes of cattle produce isopropanol in the presence of acetone but not 3-D-hydroxybutyrate. J. Dairy Sci. 83:2580-2584.   DOI   ScienceOn
26 Pothoven, A. M. and D. C. Beitz. 1975. Changes in fatty acid synthesis and lipogenic enzymes in adipose tissue from fasted and fasted-refed steers. J. Nutr. 105:1055-1061.
27 Gordon, J. C. and I. K. McAllister. 1970. The circadian rhythm of rumination. J. Agric. Sci. Camb. 74:291-297.   DOI
28 Oshiro, S., T. Oikawa and T. Katayama. 1987. A study on autocounter of masticating and ruminating behavior of goats. Anim. Sci. Technol. (Jpn.). Proceeding, Ⅶ-7. p. 176.
29 Cannan, R. K. 1965. Proposal for adoption of an international method and standard solution for hemoglobinometry, specifications for reparation of the standard solution, and notification of availability of a reference standard solution. Am. J. Clin. Pathol. 44:207-210.   DOI