• 제목/요약/키워드: internal materials

검색결과 3,156건 처리시간 0.035초

Human Pluripotent Stem Cell-Derived Alveolar Epithelial Cells as a Tool to Assess Cytotoxicity of Particulate Matter and Cigarette Smoke Extract

  • Jung-Hyun Kim;Minje Kang;Ji-Hye Jung;Seung-Joon Lee;Seok-Ho Hong
    • 한국발생생물학회지:발생과생식
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    • 제26권4호
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    • pp.155-163
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    • 2022
  • Human pluripotent stem cells (hPSCs) can give rise to a vast array of differentiated derivatives, which have gained great attention in the field of in vitro toxicity evaluation. We have previously demonstrated that hPSC-derived alveolar epithelial cells (AECs) are phenotypically and functionally similar to primary AECs and could be more biologically relevant alternatives for assessing the potential toxic materials including in fine dust and cigarette smoking. Therefore, in this study, we employed hPSC-AECs to evaluate their responses to exposure of various concentrations of diesel particulate matter (dPM), cigarette smoke extract (CSE) and nicotine for 48 hrs in terms of cell death, inflammation, and oxidative stress. We found that all of these toxic materials significantly upregulated the transcription of pro-inflammatory cytokines such as IL-1α, IL-β, IL-6, and TNF-α. Furthermore, the exposure of dPM (100 ㎍/mL) strongly induced upregulation of genes related with cell death, inflammation, and oxidative stress compared with other concentrations of CSE and nicotine. These results suggest that hPSC-AECs could be a robust in vitro platform to evaluate pulmotoxicity of various air pollutants and harmful chemicals.

투과성 방파제의 내부수위 변동과 방파제의 수리특성 (Hydraulic Characteristics of Permeable Breakwater in relation to the internal Waterlevel Fluctuation)

  • 윤한삼;전재우;류청로
    • 한국해양공학회지
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    • 제16권3호
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    • pp.46-53
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    • 2002
  • In the study, the interaction characteristics among incident waves, run-up and internal waterlevel at core layer of breakwaters were investigated. The effect of core materials on the internal waterlevel characteristics are also discussed using the results with both regular and irregular wave tests. The main results obtained are as follows; The higher internal waterleve was observed under the permeable breakwater with core layer of the lower permeability than with the higher one. And, the internal waterlevl decreased as far as the distance from the toe. In the irregular wave test, the grouping characteristics of incident waves make large fluctuation of the waterlevel. Especially, breakwaters internal waterlevel appeared to affect the hydraulic characteristics on slope.

분포 내부 감쇠 모형에 따른 회전체 계 동특성 비교 연구 (A Comparison of Dynamics of Rotor Systems for Different Internal Damping Models)

  • 박종혁;전봉석;강중옥;홍성욱
    • 한국소음진동공학회:학술대회논문집
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    • 한국소음진동공학회 2001년도 추계학술대회논문집 II
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    • pp.838-843
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    • 2001
  • Internal damping plays an important role in some rotor dynamic systems with the use of various materials for shafts, for example, composite material. However, although the effects of internal damping have been investigated for a couple of decades, there are several different internal damping models in use, none of which are accepted as the most reliable model. The purpose of this paper is to compare the results of dynamic analysis of rotor systems with several different internal damping models. The exact dynamic element method is used to formulate and analyze the problem. The simulation results provided in this paper may be useful for the dynamic analysis of high rotor systems subject to significant internal damping.

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Inconel 617의 고온열화에 따른 미세구조 및 고온 기계적 특성 (Effect of High Temperature Degradation on Microstructure and High Temperature Mechanical Properties of Inconel 617)

  • 조태선;이승호;김길수;김세훈;김영도
    • 한국재료학회지
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    • 제17권5호
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    • pp.268-272
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    • 2007
  • Inconel 617 is a candidate tube material for high temperature gas-cooled reactors(HTGR). The microstructure and mechanical properties of Inconel 617 were studied after exposure at high temperature($1050^{\circ}C$). The dominant oxide layer was Cr-oxide. The internal oxide and Cr-depleted region were observed below the Cr-oxide layer. The depth of Cr-depleted zone and internal oxide increased with exposure time. The major phases of carbides are $M_{23}C_6\;and\;M_6C$. The composition of $M_{23}C_6\;and\;M_6C$ were determined to be Cr-rich and Mo-rich, respectively. $M_6C$ carbide is more stable than $M_{23}C_6$ at high temperature. From the results of high temperature compression test, there were no significant changes in hardness and yield strength upon increasing exposure time.

적층형 압전 세라믹 액추에이터에 대한 Ag-세라믹 복합소재 전극의 응용 (Application of Ag-Ceramic Composite Electrodes to Piezoelectric Multilayer Ceramic Actuators)

  • 김성훈;이용희;조성열;최문석;이재신;김일원;정순종;송재성
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2006년도 하계학술대회 논문집 Vol.7
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    • pp.331-332
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    • 2006
  • Ag-ceramic composite materials were investigated as internal electrodes for multilayer ceramic actuators (MLCA). Ag-ceramic pastes were prepared by adding PZT-based ceramic powders to a Ag patse in a range of 0 to 50 wt.%. PZT/Ag-PZT multilayered laminates were fabricated by tape casting and fired at low temperatures below $950^{\circ}C$. The addition of ceramic into the Ag electrode resulted in a decrease in the thermal expansion mismatch between the electrode and the ceramic sheet. The maximum strain of PZT/Ag-PZT multilayered actuators were $9{\times}10^{-4}$ under an electric field of 2.5MV/m. In conclusion, Ag-PZT composite materials are efficient for low cost piezoelectric MLCAs.

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Influence of abutment materials on the implant-abutment joint stability in internal conical connection type implant systems

  • Jo, Jae-Young;Yang, Dong-Seok;Huh, Jung-Bo;Heo, Jae-Chan;Yun, Mi-Jung;Jeong, Chang-Mo
    • The Journal of Advanced Prosthodontics
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    • 제6권6호
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    • pp.491-497
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    • 2014
  • PURPOSE. This study evaluated the influence of abutment materials on the stability of the implant-abutment joint in internal conical connection type implant systems. MATERIALS AND METHODS. Internal conical connection type implants, cement-retained abutments, and tungsten carbide-coated abutment screws were used. The abutments were fabricated with commercially pure grade 3 titanium (group T3), commercially pure grade 4 titanium (group T4), or Ti-6Al-4V (group TA) (n=5, each). In order to assess the amount of settlement after abutment fixation, a 30-Ncm tightening torque was applied, then the change in length before and after tightening the abutment screw was measured, and the preload exerted was recorded. The compressive bending strength was measured under the ISO14801 conditions. In order to determine whether there were significant changes in settlement, preload, and compressive bending strength before and after abutment fixation depending on abutment materials, one-way ANOVA and Tukey's HSD post-hoc test was performed. RESULTS. Group TA exhibited the smallest mean change in the combined length of the implant and abutment before and after fixation, and no difference was observed between groups T3 and T4 (P>.05). Group TA exhibited the highest preload and compressive bending strength values, followed by T4, then T3 (P<.001). CONCLUSION. The abutment material can influence the stability of the interface in internal conical connection type implant systems. The strength of the abutment material was inversely correlated with settlement, and positively correlated with compressive bending strength. Preload was inversely proportional to the frictional coefficient of the abutment material.

경화공정에 따른 복합재 부품 외부와 내부의 경화 거동 차이에 대한 연구 (Study of Cure Behavior of the External and Internal of Composite Parts)

  • 현동근;이동승;신도훈;김지훈
    • Composites Research
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    • 제33권5호
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    • pp.302-308
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    • 2020
  • 본 연구는 탄소 복합소재를 이용하여 오토클레이브와 진공백(Vacuum Bag Only) 공정으로 소재의 열전도 계수를구하고 경화 거동 모델을 통해 표면부와 내부의 경화 거동을 예측 및 비교하였다. 공정에 따른 열전도 계수의 변화로 인해 내부 온도가 표면부와 차이를 보였다. 오토클레이브 공정의 경우 높은 열전도 계수를 통하여 표면부와 내부의 온도는 거의 일치를 하였으며, 경화 거동 역시 유사하게 진행이 되었다. 하지만, 진공백 공정의 경우 표면부와 내부의 경화 거동이 많은 차이를 보였다. 이 차이는 부품 내부의 품질 및 공기 배출에 영향을 준다. 기계적 물성 차이를 확인하고자 0도 단방향 시편으로 압축시험을 수행하였고, 그 결과 진공백 성형이 조금 낮은 물성을 갖는다는 것을 확인하였다.

튜브 액압성형 공정의 가이드영역에서 소재 및 윤활에 따른 마찰 특성의 실험적 연구 (Experimental investigation of friction in guide zone of tube hydroforming with material and lubricant)

  • 이혜경;임홍섭;이건엽;이성문;정기석;문영훈
    • 한국소성가공학회:학술대회논문집
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    • 한국소성가공학회 2008년도 추계학술대회 논문집
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    • pp.83-86
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    • 2008
  • In this study, friction test was proposed to obtain coefficient of friction between tube and die in guide zone of tube hydroforming and friction coefficients were evaluated at different materials, viscosity of lubricants and internal pressures. For this study, STKM11A and SUS tubes were prepared. The tube was expanded by an internal pressure against the tool wall. By pushing the tube through the tool, a friction force at the contact surface between the tube and the tool occurs From the recorded axial feeding forces, the friction coefficients between tube and die at the guide zone in tubular hydroforming can be estimated. The effects of the various internal pressures, viscosity of lubricants, tube materials, tube size and die coating on the friction forces and friction coefficients are discussed.

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대나무(대체근계)의 토질강도보강효과에 대한 실험적 연구 -토양수분제어하의 단순전단시험에 의한 해석- (Experimental Study on Reinforcement Effectives of Soil Shear Strength by Bamboo(Substitute Materials Simulating a Root System) -Analysis caused by Simple Shear Test under Soil Suction Control-)

  • 이창우
    • 한국환경복원기술학회지
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    • 제7권2호
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    • pp.46-51
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    • 2004
  • In this paper, reinforcement of soil shear strength by bamboo(substitute materials simulating a root system) are evaluated by soil strength parameters(apparent cohesion(c) and internal friction angle(tan${\Phi}$)), using simple shear tester which clearly depicts shear deformation and controls soil suction. The results show that the internal friction angle does not change under various soil suction conditions but the apparent cohesion, which reach a peak in suction of 45cm$H_2O$ near critical capillary head, is effected by soil suction. And the reinforcement of soil strength by bamboo are expressed by apparent cohesion more than internal friction angle. In addition the increment of apparent cohesion by bamboo reached a peak in suction 45cm$H_2O$ too.