• Journal of the Korean Institute of Gas
• /
• v.10 no.1 s.30
• /
• pp.32-37
• /
• 2006

Major components of refinery plants are exposed to various damage mechanisms depending on the operation condition, material selection and kinds of internal fluid. Inspection techniques and damage monitoring methods should be selected considering the damage mechanisms of the components. Hence, it is quite necessary to have an information system with a standardized database on the various damage mechanisms. In this study a damage information system with contents on the damage mechanisms included in API 571 code was developed. Concept of the screening table employed in USA and Japan was also adopted to identify the probable damage mechanisms from the information on operating temperature, internal fluid, metal used for the component and stress condition. This system can be used before the risk based inspection planning to identify key damage mechanisms involved.

• Herbal Formula Science
• /
• v.17 no.2
• /
• pp.225-231
• /
• 2009

Heterotopic ossification is often complicated in patients with brain injury. It occurs in the connective tissue of skeletal muscle close to a joint, especially most highly in the hip joint. This study have reported a case of heterotopic ossification in hypoxic brain damage patient due to cardiac attack. Binso-san is known by medication on arthritis. It has an effect on pain control or reduce of swelling in the joints. This study suggest that Binso-san has an improving effect on hip joint affected by Heterotopic ossification.

• Tuberculosis and Respiratory Diseases
• /
• v.72 no.4
• /
• pp.386-389
• /
• 2012

Diffuse alveolar damage (DAD) is a histological change in lung tissue, and is generally caused by an acute lung injury, which is characterized by bilateral and widespread damages. Localized DAD occurs very rarely. The causes for DAD are numerous, but the chief cause is acute interstitial pneumonia or acute exacerbation of idiopathic interstitial pneumonia, in cases of idiopathic manifestation. The 82-year-old patient, in this case study, showed a DAD lesion in only 1 lobe. The patient was otherwise healthy, with no previous symptoms of DAD. He was admitted to our medical center owing to localized infiltration, observed on his chest radiograph. Laboratory studies showed no signs of infections. DAD was confirmed by a surgical lung biopsy. The patient received corticosteroid treatment and had gradually improved. We report the case of a patient with localized, idiopathic DAD that cannot be classified as acute interstitial pneumonia or acute exacerbation of idiopathic interstitial pneumonia.

• The Journal of Internal Korean Medicine
• /
• v.22 no.2
• /
• pp.127-134
• /
• 2001

The purpose of this investigation is to evaluate the effects of Samwha-tang(三化湯) Extracts on reversible forebrain ischemia experimentally induced from the occlusion of middle cerebral artery. The volume of cerebral ischemia, the volume of cerebral edema, and the change of pyramidal neuron of the CA1 area in hippocampus through light microscopy were investigated. we obtained the following results. The volume of the control group, which had ischemic damage was 21%, and the volume of the sample group, which had ischemic damage, was 16%. The ratio of the volume of the right/left hemisphere was 117.2 in the control group, and 108.8 in the sample group. Also, the light microscopy revealed that the pyramidal cells of CA1 area in hippocampus had many damages like changes into discontinuous and unsystematic forms. But, in the sample group, the cells were less damaged compared with the control group.

• Journal of Veterinary Clinics
• /
• v.38 no.4
• /
• pp.189-193
• /
• 2021

An 11-years old spayed female Persian chinchilla cat presented with acute onset of blindness from bilateral retinal detachment and systemic hypertension. On physical examination, the cat was tachycardic (240 beats/min) with a systolic blood pressure of around 250 mmHg. Clinical findings, blood works, urinalysis, thyroid function test, radiography, echocardiogram, and ultrasonography were performed to rule out underlying diseases. Organ injury induced by systemic hypertension including bilateral retinal detachment and left ventricular hypertrophy were confirmed by ultrasound. Based on these results, it was diagnosed as feline idiopathic hypertension with target organ damage (TOD). The cat was treated with a combination therapy using high doses of amlodipine, telmisartan, and atenolol. After the treatment, its hypertension and TOD were improved. This case showed that appropriate therapeutic management can help prevent TOD associated with feline hypertension.

• The Journal of Internal Korean Medicine
• /
• v.42 no.6
• /
• pp.1269-1284
• /
• 2021

Objectives: Phragmitis Rhizoma is the fresh or dried rhizome of Phragmites communis Trin., which has been prescribed in traditional Korean medicine to relieve fever and vomiting and to nourish the body fluids. Recently, the protective effect of Phragmitis Rhizoma extract or its components on myelotoxicity and inflammatory responses have been reported, but no study has yet been conducted on oxidative stress. Methods: The present study investigated whether an ethanol extract of Phragmitis Rhizoma (PR) could protect against cellular damage induced by oxidative stress in Chang liver cells. Results: Pretreatment with PR significantly suppressed the hydrogen peroxide (H₂O₂)-induced reduction of Chang cell viability and generation of reactive oxygen species (ROS), thereby deferring apoptosis. PR also markedly inhibited H₂O₂-induced comet tail formation and phospho-γH2AX expression, suggesting that PR protected against oxidative stress-mediated DNA damage. PR also effectively prevented the inhibition of ATP synthesis in H₂O₂-treated Chang cells by inhibiting the loss of mitochondrial membrane potential, indicating that PR maintains energy metabolism through preservation of mitochondrial function while eliminating ROS generated by H₂O₂. Immunoblotting results indicated that PR attenuated the H₂O₂-induced downregulation of Bcl-2 and upregulation of Bax expression. Conclusions: PR protects against oxidative injury in Chang liver cells by regulating energy homeostasis via ROS generation blockade, which is at least partly mediated through inactivation of the mitochondria-mediated apoptosis pathway.

• Selected Papers of The Society of Naval Architects of Korea
• /
• v.2 no.1
• /
• pp.106-128
• /
• 1994

An elasto-plastic-damage constitutive model for ductile materials is proposed within the framework of a thermodynamic approach of continuum damage mechanics (CDM) in which internal irreversible thermodynamic changes of micro-structure of materials such as plastic deformation and damage evolution are considered as thermodynamic state variables. The new constitutive model can predict not only the elasto-plastic behaviors but also the sequential stiffness degradation process of ductile materials more rationally.

• Steel and Composite Structures
• /
• v.1 no.3
• /
• pp.283-294
• /
• 2001

In the present work a constitutive model is developed which permits the assessment of the structural performance through a criterion based on cumulative damage. For it, a damage index is defined and is evaluated through the application of the Miner's rule in low-cycle fatigue. However, the damage index is not considered as a posteriori variable since is incorporated explicitly as an internal variable in the constitutive equations which produces a direct coupling between the damage and the structural mechanical behaviour allowing the possibility of considering as a whole different coupled phenomena. For the elaboration of this damage model, the concepts of the mechanics of continuum medium are applied on lumped dissipative models in order to obtain a coupled simplified model. As a result an elastoplastic model coupled with damage and fatigue damage is obtained.

• The Journal of Internal Korean Medicine
• /
• v.25 no.4
• /
• pp.410-417
• /
• 2004

Fever is a rise in body temperature from any of a variety of causes. One might even feel a fever when body temperature is normal. An imbalance of Yin and Yang due to exogenous pathogenic factors or internal damage is usually considered the cause of fever in Oriental Medicine. Fever from deficiency of Qi is one of the major components of the theory of fever due to internal damage. Clinically, such cases are usually encountered along with wasting diseases and fever does not run high. The compliment of Qi is usually considered the appropriate treatment in these cases. Oriental Medical treatment was performed using herbal medicine after the cause of fever was diagnosed as deficiency of Qi. The herb medicine used in these cases was mainly Bojoongikki-tang(補中益氣湯). Through those treatments good results were seen. More clinical case reports are needed.

• The Journal of the Convergence on Culture Technology
• /
• v.10 no.1
• /
• pp.585-590
• /
• 2024

In this study, rail surface defects are increasing due to the aging of urban railway rails, but in the detailed guidelines for track performance evaluation established by the country, rail surface damage is inspected with the naked eye of engineers and simple measuring tools. With the recent enactment of the Track Diagnosis Act, a large budget has been invested and the volume of rail diagnosis is rapidly increasing, but it is difficult to secure the reliability of diagnosis results using labor-intensive visual inspection techniques. It is very important to discover defects in the rail surface through periodic track tours and visual inspection. However, evaluating the severity of defects on the rail surface based on the subjective judgment of the inspector has significant limitations in predicting damage inside the rail. In this study, the rail internal crack characteristics due to rail surface damage were studied. In field measurements, rail surface damage locations were selected, samples of various damage types were collected, and the rail surface damage status was evaluated. In indoor testing, we intend to analyze the correlation between rail surface defects and internal defects using a electron scanning microscope (SEM). To determine the crack growth rate of urban railway rails currently in use, the Gaussian probability density function was applied and analyzed.