Browse > Article
http://dx.doi.org/10.17555/jvc.2021.38.4.189

Management of Feline Idiopathic Hypertension with Target Organ Damage: A Case Report  

Lee, Ji-Hye (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonnam National University)
Kim, Jihee (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonnam National University)
Kim, Yoonji (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonnam National University)
Kim, Soomin (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonnam National University)
Kim, Hyeon-Jin (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonnam National University)
Kim, Ha-Jung (Department of Veterinary Internal Medicine, College of Veterinary Medicine, Chonnam National University)
Publication Information
Journal of Veterinary Clinics / v.38, no.4, 2021 , pp. 189-193 More about this Journal
Abstract
An 11-years old spayed female Persian chinchilla cat presented with acute onset of blindness from bilateral retinal detachment and systemic hypertension. On physical examination, the cat was tachycardic (240 beats/min) with a systolic blood pressure of around 250 mmHg. Clinical findings, blood works, urinalysis, thyroid function test, radiography, echocardiogram, and ultrasonography were performed to rule out underlying diseases. Organ injury induced by systemic hypertension including bilateral retinal detachment and left ventricular hypertrophy were confirmed by ultrasound. Based on these results, it was diagnosed as feline idiopathic hypertension with target organ damage (TOD). The cat was treated with a combination therapy using high doses of amlodipine, telmisartan, and atenolol. After the treatment, its hypertension and TOD were improved. This case showed that appropriate therapeutic management can help prevent TOD associated with feline hypertension.
Keywords
calcium channel blocker; angiotensin-converting-enzyme inhibitor; angiotensin II receptor blocker; systemic hypertension; cat;
Citations & Related Records
연도 인용수 순위
  • Reference
1 Lesser M, Fox PR, Bond BR. Assessment of hypertension in 40 cats with left ventricular hypertrophy by Doppler-shift sphygmomanometry. J Small Anim Pract 1992; 33: 55-58.   DOI
2 Van Boxtel SA. Hypertensive retinopathy in a cat. Can Vet J 2003; 44: 147-149.
3 Henik RA, Stepien RL, Wenholz LJ, Dolson MK. Efficacy of atenolol as a single antihypertensive agent in hyperthyroid cats. J Feline Med Surg 2008; 10: 577-582.   DOI
4 Chetboul V, Lefebvre HP, Pinhas C, Clerc B, Boussouf M, Pouchelon JL. Spontaneous feline hypertension: clinical and echocardiographic abnormalities, and survival rate. J Vet Intern Med 2003; 17: 89-95.   DOI
5 Elliott J, Barber PJ, Syme HM, Rawlings JM, Markwell PJ. Feline hypertension: clinical findings and response to antihypertensive treatment in 30 cases. J Small Anim Pract 2001; 42: 122-129.   DOI
6 Dunn FG, Chandraratna P, deCarvalho JG, Basta LL, Frohlich ED. Pathophysiologic assessment of hypertensive heart disease with echocardiography. Am J Cardiol 1977; 39: 789-795.   DOI
7 Glaus TM, Elliott J, Herberich E, Zimmering T, Albrecht B. Efficacy of long-term oral telmisartan treatment in cats with hypertension: results of a prospective European clinical trial. J Vet Intern Med 2019; 33: 413-422.   DOI
8 Acierno MJ, Brown S, Coleman AE, Jepson RE, Papich M, Stepien RL, et al. ACVIM consensus statement: guidelines for the identification, evaluation, and management of systemic hypertension in dogs and cats. J Vet Intern Med 2018; 32: 1803-1822.   DOI
9 Bijsmans ES, Doig M, Jepson RE, Syme HM, Elliott J, Pelligand L. Factors influencing the relationship between the dose of amlodipine required for blood pressure control and change in blood pressure in hypertensive cats. J Vet Intern Med 2016; 30: 1630-1636.   DOI
10 Conroy M, Chang YM, Brodbelt D, Elliott J. Survival after diagnosis of hypertension in cats attending primary care practice in the United Kingdom. J Vet Intern Med 2018; 32: 1846-1855.   DOI
11 Taylor SS, Sparkes AH, Briscoe K, Carter J, Sala SC, Jepson RE, et al. ISFM consensus guidelines on the diagnosis and management of hypertension in cats. J Feline Med Surg 2017; 19: 288-303.   DOI
12 Erickson PA, Fisher SK, Anderson DH, Stern WH, Borgula GA. Retinal detachment in the cat: the outer nuclear and outer plexiform layers. Invest Ophthalmol Vis Sci 1983; 24: 927-942.
13 Jepson RE. Feline systemic hypertension: classification and pathogenesis. J Feline Med Surg 2011; 13: 25-34.   DOI
14 Sent U, Gossl R, Elliott J, Syme HM, Zimmering T. Comparison of efficacy of long-term oral treatment with telmisartan and benazepril in cats with chronic kidney disease. J Vet Intern Med 2015; 29: 1479-1487.   DOI
15 Young WM, Zheng C, Davidson MG, Westermeyer HD. Visual outcome in cats with hypertensive chorioretinopathy. Vet Ophthalmol 2019; 22: 161-167.   DOI
16 Kemp BA, Howell NL, Keller SR, Gildea JJ, Padia SH, Carey RM. AT2 receptor activation prevents sodium retention and reduces blood pressure in angiotensin II-dependent hypertension. Circ Res 2016; 119: 532-543.   DOI