• 제목/요약/키워드: inorganic

검색결과 5,587건 처리시간 0.036초

Inorganic sulfur reduces cell proliferation by inhibiting of $ErbB_2$ and $ErbB_3$ protein and mRNA expression in MDA-MB-231 human breast cancer cells

  • Ha, Ae Wha;Hong, Kyung Hee;Kim, Hee Sun;Kim, Woo Kyoung
    • Nutrition Research and Practice
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    • 제7권2호
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    • pp.89-95
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    • 2013
  • Dietary inorganic sulfur is the minor component in our diet, but some studies suggested that inorganic sulfur is maybe effective to treat cancer related illness. Therefore, this study aims to examine the effects of inorganic sulfur on cell proliferation and gene expression in MDA-MB-231 human breast cancer cells. MDA-MB-231 cells were cultured the absence or presence of various concentrations (12.5, 25, or 50 ${\mu}mol/L$) of inorganic sulfur. Inorganic sulfur significantly decreased proliferation after 72 h of incubation (P < 0.05). The protein expression of $ErbB_2$ and its active form, $pErbB_2$, were significantly reduced at inorganic sulfur concentrations of 50 ${\mu}mol/L$ and greater than 25 ${\mu}mol/L$, respectively (P < 0.05). The mRNA expression of $ErbB_2$ was significantly reduced at an inorganic sulfur concentration of 50 ${\mu}mol/L$ (P < 0.05). The protein expression of $ErbB_3$ and its active form, $pErbB_3$, and the mRNA expression of $pErbB_3$ were significantly reduced at inorganic sulfur concentrations greater than 25 ${\mu}mol/L$ (P < 0.05). The protein and mRNA expression of Akt were significantly reduced at an inorganic sulfur concentration of 50 ${\mu}mol/L$ (P < 0.05), but pAkt was not affected by inorganic sulfur treatment. The protein and mRNA expression of Bax were significantly increased with the addition of inorganic sulfur concentration of 50 ${\mu}mol/L$ (P < 0.05). In conclusion, cell proliferation was suppressed by inorganic sulfur treatment through the ErbB-Akt pathway in MDA-MB-231 cells.

Nylon-Inorganic Filler Alloy상의 니켈 도금 기술 (Nickel Plating Techniques of Nylon-Inorganic Filler Alloy)

  • 노윤찬
    • 공업화학
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    • 제10권1호
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    • pp.67-72
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    • 1999
  • Nylon-inorganic filler alloy의 도금에 있어 최적 전처리 공정에 관하여 연구하였다. Nylon-inorganic filler alloy는 etching 공정만으로도 무정형층을 제거하여 요구되는 충분한 밀착력을 얻을 수 있었다. SEM과 표면조도 측정으로부터 etching 공정이 수지표면을 매우 거칠고 접착력을 우수하게 만든다는 결과를 얻었으며, 도금물질의 표면상태와 접착력은 Nylon-inorganic filler alloy 수지의 성형조건에 의존한다는 것을 확인하였다. EDS 분석으로 전처리 후 수지표면의 잔류금속의 종류와 양을 측정한 결과 Cr은 Sn과 Pd의 흡착에 크게 영향을 미치지 않는 것으로 나타났다.

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Inorganic sulfur reduces the motility and invasion of MDA-MB-231 human breast cancer cells

  • Kim, Jin-Joo;Ha, Hwa-Ae;Kim, Hee-Sun;Kim, Woo-Kyoung
    • Nutrition Research and Practice
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    • 제5권5호
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    • pp.375-380
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    • 2011
  • This study investigated the effects of inorganic sulfur on metastasis in MDA-MB-231 human breast cancer cells. MDA-MB-231 cells were cultured in the absence or presence of various concentrations (12.5, 25, or 50 ${\mu}mol$/L) of inorganic sulfur. Cell motility, invasion, and the activity and mRNA expression of matrix metalloproteases (MMPs) were examined. Numbers of viable MDA-MB-231 cells did not differ by inorganic sulfur treatment from 0 to 50 ${\mu}mol$/L within 48 h. Inorganic sulfur significantly decreased cell motility and invasion in the MDA-MB-231 cells in a dose-dependent manner (P<0.05), as determined using a Boyden chamber assay and a Matrigel chamber. The activities of MMP-2 and MMP-9 were significantly reduced by inorganic sulfur in a dose-dependent manner (P<0.05). The inorganic sulfur also significantly inhibited MMP-2 and MMP-9 expression in the cells (P<0.05). These data suggest that inorganic sulfur can suppress cancer cell motility and invasion by inhibiting MMP-2 and MMP-9 activity and gene expression in MDA-MB-231 cells.

Physical Properties of Cement System Insulation Using Blast Furnace Slag

  • Seo, Sung Kwan;Park, Jae Wan;Cho, Hyeong Kyu;Chu, Yong Sik
    • 한국세라믹학회지
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    • 제55권1호
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    • pp.61-66
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    • 2018
  • In this study, fabrication method of inorganic insulation were studied to reduce $CO_2$ from buildings. Main materials for inorganic insulation were used cement, blast furnace slag and aluminum powder as foaming agent. Mixing ratio of cement and slag was controlled and physical properties of inorganic insulation were analyzed. When inorganic insulation was fabricated using cement and slag, expanded slurries were not sunken and hardened normally. Pore size was 0.5 - 2 mm; mean pore size was about 1mm in inorganic insulation. Compressive strength of inorganic insulation increased with curing time and increased slightly with cement fineness. However, specific gravity decreased slightly with curing time; this phenomenon was caused by evaporation of adsorptive water. When inorganic insulation was dried at $60^{\circ}C$, compressive strength was higher than that of undried insulation. The highest compressive strength was found with a mixture of cement (50%) and slag (30%) in inorganic insulation. Compressive strength was 0.32 MPa, thermal conductivity was 0.043 W/mK and specific gravity was $0.12g/cm^3$.

천연 무기 광물계 혼화재료를 혼입한 철근콘크리트 구조물의 부식저항성에 관한 연구 (A Study on Corrosion Resistance of Reinforced Concrete Structures using Natural Inorganic Minerals)

  • 태성호;박재영;김재영;박재승;경제운;남호윤
    • KIEAE Journal
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    • 제7권4호
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    • pp.127-133
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    • 2007
  • As a fundamental study on the corrosion resistance of reinforced concrete structures using Natural Inorganic Minerals exposed to carbonation environment, The test specimens were concrete(W/C=60%) with Natural Inorganic Minerals content of 0%, 10%. Accelerated carbonation and autoclave corrosion accelerated curing were then conducted with them. The corrosion resistance of steel in concrete with Natural Inorganic Minerals content of 0%, 10% was examined by corrosion form, half-cell potential, polarization resistance, corrosion area and weight loss after 24 hours of autoclave corrosion accelerated curing.The results of the study showed that as for steel in concrete with Natural Inorganic Minerals content of 10%, the corrosion resistance was more excellent than steel in concrete with Natural Inorganic Minerals content of 0%.

경량무기발포 세라믹보드 및 무기단열재의 함수율에 따른 단열특성 (Characteristic of Insulation with Moisture Content Light-weight Inorganic Foam Ceramic Board)

  • 신현욱;송훈;추용식;이종규
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2013년도 추계 학술논문 발표대회
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    • pp.198-199
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    • 2013
  • To prevent energy waste in buildings used heat insulator. Heat insulator materials can be classified inorganic and organic. The inorganic material has lower water resistance. The inorganic material is heavy and worse thermal performance than organic materials. Technologies on energy saving and materials used in curtain walls have progressed with increase of high-rise and large buildings. However, there is little study to explain water resistance performance of the curtain walls. This study focused on evaluation of insulation of inorganic materials and performance evaluation by thermal conductivity.

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경량 무기 단열재에 관한 연구 (A Study on Light-weight Inorganic Insulation)

  • 신현욱;송훈;추용식;이종규
    • 한국건축시공학회:학술대회논문집
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    • 한국건축시공학회 2012년도 춘계 학술논문 발표대회
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    • pp.217-218
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    • 2012
  • To prevent energy waste in buildings used heat insulator. Heat insulator materials can be classified inorganic and organic. The organic material is be toxic gas emission, when a fire occurs. And it has lower water resistance. The inorganic material is heavy and worse thermal performance than organic materials. This study focused on thermal conductivity and density of inorganic foam material for using industrial by-products materials.

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Removal of Inorganic Nitrogen and Phosphorus from Cow s Liquid Manure by Batch Algal Culture

  • KIM, MAM-SOO;MOO-YOUNG PACK
    • Journal of Microbiology and Biotechnology
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    • 제3권3호
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    • pp.214-216
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    • 1993
  • Cow's liquid manure (CLM), an animal waste, was treated by a batch algal culture to remove inorganic nutrients. CLM used in this study was especially high in concentrations of inorganic nitrogen and phosphorus. The optimum dilution ratio of the CLM for maximum algal growth was 1:25. Ninety five percent of inorganic nitrogen and 100% of inorganic phosphorus were removed from the CLM with a dilution ratio of 1:25.

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