• Title/Summary/Keyword: inorganic

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Inorganic sulfur reduces cell proliferation by inhibiting of $ErbB_2$ and $ErbB_3$ protein and mRNA expression in MDA-MB-231 human breast cancer cells

  • Ha, Ae Wha;Hong, Kyung Hee;Kim, Hee Sun;Kim, Woo Kyoung
    • Nutrition Research and Practice
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    • v.7 no.2
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    • pp.89-95
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    • 2013
  • Dietary inorganic sulfur is the minor component in our diet, but some studies suggested that inorganic sulfur is maybe effective to treat cancer related illness. Therefore, this study aims to examine the effects of inorganic sulfur on cell proliferation and gene expression in MDA-MB-231 human breast cancer cells. MDA-MB-231 cells were cultured the absence or presence of various concentrations (12.5, 25, or 50 ${\mu}mol/L$) of inorganic sulfur. Inorganic sulfur significantly decreased proliferation after 72 h of incubation (P < 0.05). The protein expression of $ErbB_2$ and its active form, $pErbB_2$, were significantly reduced at inorganic sulfur concentrations of 50 ${\mu}mol/L$ and greater than 25 ${\mu}mol/L$, respectively (P < 0.05). The mRNA expression of $ErbB_2$ was significantly reduced at an inorganic sulfur concentration of 50 ${\mu}mol/L$ (P < 0.05). The protein expression of $ErbB_3$ and its active form, $pErbB_3$, and the mRNA expression of $pErbB_3$ were significantly reduced at inorganic sulfur concentrations greater than 25 ${\mu}mol/L$ (P < 0.05). The protein and mRNA expression of Akt were significantly reduced at an inorganic sulfur concentration of 50 ${\mu}mol/L$ (P < 0.05), but pAkt was not affected by inorganic sulfur treatment. The protein and mRNA expression of Bax were significantly increased with the addition of inorganic sulfur concentration of 50 ${\mu}mol/L$ (P < 0.05). In conclusion, cell proliferation was suppressed by inorganic sulfur treatment through the ErbB-Akt pathway in MDA-MB-231 cells.

Nickel Plating Techniques of Nylon-Inorganic Filler Alloy (Nylon-Inorganic Filler Alloy상의 니켈 도금 기술)

  • Roh, Yun-Chan
    • Applied Chemistry for Engineering
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    • v.10 no.1
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    • pp.67-72
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    • 1999
  • Optimal pretreatment processes for metal plating on engineering plastics, especially on Nylon-inorganic filler alloy was studied. For Nylon-inorganic filler alloy, adhesion strength between resin surface and metal could be improved by just etching process that eliminate amorphous layer. In the SEM picture and surface roughness measurement, etching treatment was found to make enabled the surface condition very rough and the adhesion strength good. It was also found that the surface condition of plated article and its adhesion strength partly depended upon molding condition of Nylon-inorganic filler alloy. EDS, peaks showed that what kinds of and how much of the metal elements remained on the resin surface after pretreatment processes. Cr did not affect on adsorption of Sn and Pd remarkably.

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Inorganic sulfur reduces the motility and invasion of MDA-MB-231 human breast cancer cells

  • Kim, Jin-Joo;Ha, Hwa-Ae;Kim, Hee-Sun;Kim, Woo-Kyoung
    • Nutrition Research and Practice
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    • v.5 no.5
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    • pp.375-380
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    • 2011
  • This study investigated the effects of inorganic sulfur on metastasis in MDA-MB-231 human breast cancer cells. MDA-MB-231 cells were cultured in the absence or presence of various concentrations (12.5, 25, or 50 ${\mu}mol$/L) of inorganic sulfur. Cell motility, invasion, and the activity and mRNA expression of matrix metalloproteases (MMPs) were examined. Numbers of viable MDA-MB-231 cells did not differ by inorganic sulfur treatment from 0 to 50 ${\mu}mol$/L within 48 h. Inorganic sulfur significantly decreased cell motility and invasion in the MDA-MB-231 cells in a dose-dependent manner (P<0.05), as determined using a Boyden chamber assay and a Matrigel chamber. The activities of MMP-2 and MMP-9 were significantly reduced by inorganic sulfur in a dose-dependent manner (P<0.05). The inorganic sulfur also significantly inhibited MMP-2 and MMP-9 expression in the cells (P<0.05). These data suggest that inorganic sulfur can suppress cancer cell motility and invasion by inhibiting MMP-2 and MMP-9 activity and gene expression in MDA-MB-231 cells.

Physical Properties of Cement System Insulation Using Blast Furnace Slag

  • Seo, Sung Kwan;Park, Jae Wan;Cho, Hyeong Kyu;Chu, Yong Sik
    • Journal of the Korean Ceramic Society
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    • v.55 no.1
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    • pp.61-66
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    • 2018
  • In this study, fabrication method of inorganic insulation were studied to reduce $CO_2$ from buildings. Main materials for inorganic insulation were used cement, blast furnace slag and aluminum powder as foaming agent. Mixing ratio of cement and slag was controlled and physical properties of inorganic insulation were analyzed. When inorganic insulation was fabricated using cement and slag, expanded slurries were not sunken and hardened normally. Pore size was 0.5 - 2 mm; mean pore size was about 1mm in inorganic insulation. Compressive strength of inorganic insulation increased with curing time and increased slightly with cement fineness. However, specific gravity decreased slightly with curing time; this phenomenon was caused by evaporation of adsorptive water. When inorganic insulation was dried at $60^{\circ}C$, compressive strength was higher than that of undried insulation. The highest compressive strength was found with a mixture of cement (50%) and slag (30%) in inorganic insulation. Compressive strength was 0.32 MPa, thermal conductivity was 0.043 W/mK and specific gravity was $0.12g/cm^3$.

A Study on Corrosion Resistance of Reinforced Concrete Structures using Natural Inorganic Minerals (천연 무기 광물계 혼화재료를 혼입한 철근콘크리트 구조물의 부식저항성에 관한 연구)

  • Tae, Sung Ho;Park, Jae Young;Kim, Jae Young;Park, Jae Seung;Kyung, Je Woon;Nam, Ho Yoon
    • KIEAE Journal
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    • v.7 no.4
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    • pp.127-133
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    • 2007
  • As a fundamental study on the corrosion resistance of reinforced concrete structures using Natural Inorganic Minerals exposed to carbonation environment, The test specimens were concrete(W/C=60%) with Natural Inorganic Minerals content of 0%, 10%. Accelerated carbonation and autoclave corrosion accelerated curing were then conducted with them. The corrosion resistance of steel in concrete with Natural Inorganic Minerals content of 0%, 10% was examined by corrosion form, half-cell potential, polarization resistance, corrosion area and weight loss after 24 hours of autoclave corrosion accelerated curing.The results of the study showed that as for steel in concrete with Natural Inorganic Minerals content of 10%, the corrosion resistance was more excellent than steel in concrete with Natural Inorganic Minerals content of 0%.

Characteristic of Insulation with Moisture Content Light-weight Inorganic Foam Ceramic Board (경량무기발포 세라믹보드 및 무기단열재의 함수율에 따른 단열특성)

  • Shin, Hyeon-Uk;Song, Hun;Chu, Yong-Sik;Lee, Jong-Kyu
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2013.11a
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    • pp.198-199
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    • 2013
  • To prevent energy waste in buildings used heat insulator. Heat insulator materials can be classified inorganic and organic. The inorganic material has lower water resistance. The inorganic material is heavy and worse thermal performance than organic materials. Technologies on energy saving and materials used in curtain walls have progressed with increase of high-rise and large buildings. However, there is little study to explain water resistance performance of the curtain walls. This study focused on evaluation of insulation of inorganic materials and performance evaluation by thermal conductivity.

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A Study on Light-weight Inorganic Insulation (경량 무기 단열재에 관한 연구)

  • Shin, Hyeon-Uk;Song, Hun;Chu, Yong-Sik;Lee, Jong-Kyu
    • Proceedings of the Korean Institute of Building Construction Conference
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    • 2012.05a
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    • pp.217-218
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    • 2012
  • To prevent energy waste in buildings used heat insulator. Heat insulator materials can be classified inorganic and organic. The organic material is be toxic gas emission, when a fire occurs. And it has lower water resistance. The inorganic material is heavy and worse thermal performance than organic materials. This study focused on thermal conductivity and density of inorganic foam material for using industrial by-products materials.

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Removal of Inorganic Nitrogen and Phosphorus from Cow s Liquid Manure by Batch Algal Culture

  • KIM, MAM-SOO;MOO-YOUNG PACK
    • Journal of Microbiology and Biotechnology
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    • v.3 no.3
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    • pp.214-216
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    • 1993
  • Cow's liquid manure (CLM), an animal waste, was treated by a batch algal culture to remove inorganic nutrients. CLM used in this study was especially high in concentrations of inorganic nitrogen and phosphorus. The optimum dilution ratio of the CLM for maximum algal growth was 1:25. Ninety five percent of inorganic nitrogen and 100% of inorganic phosphorus were removed from the CLM with a dilution ratio of 1:25.

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