• Parasites, Hosts and Diseases
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• v.27 no.1
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• pp.41-46
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• 1989

This study was performed to observe the infection rate and infection intensity of fresh water fish such as pale chub (Z. platypus) and dark chub (Z. temminckii) with the metacercariae of C. armatus. The fish were caught in several rivers and streams from June to September, 1988 and examined by artificial digestion technique. Total 370 fish were caught at 19 rivers. The metacercarial (C. armatus) infection rate and average burden in Z. Platypus were 86.8% and 224, and those in Z. tsmminckii were 78.5% and 131. The infection rate and burden per fish were 73.4% and 32 in the fish caught from the Han river, and 88.0% and 44 from the Youngsan river. All fish caught from the Keum and the Tamjin river were infected and their mean metacercarial density was 45 and 59 respectively. The infection rate and density in fish caught from the Seomjin and Nagdong rivers were 100% and 119, and 81.0% and 348 respectively. From this study, it is confirmed that C. armatus is widely distributed along 5 major rivers in Korea.

• Parasites, Hosts and Diseases
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• v.51 no.6
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• pp.663-667
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• 2013

Free-grazing ducks play a major role in the rural economy of Eastern Asia in the form of egg and meat production. In Thailand, the geographical location, tropical climate conditions and wetland areas of the country are suitable for their husbandry. These environmental factors also favor growth, multiplication, development, survival, and spread of duck parasites. In this study, a total of 90 free-grazing ducks from northern, central, and northeastern regions of Thailand were examined for intestinal helminth parasites, with special emphasis on zoonotic echinostomes. Of these, 51 (56.7%) were infected by one or more species of zoonotic echinostomes, Echinostoma revolutum, Echinoparyphium recurvatum, and Hypoderaeum conoideum. Echinostomes found were identified using morphological criteria when possible. ITS2 sequences were used to identify juvenile and incomplete worms. The prevalence of infection was relatively high in each region, namely, north, central, and northeast region was 63.2%, 54.5%, and 55.3%, respectively. The intensity of infection ranged up to 49 worms/infected duck. Free-grazing ducks clearly play an important role in the life cycle maintenance, spread, and transmission of these medically important echinostomes in Thailand.

• Journal of Aquaculture
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• v.19 no.4
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• pp.236-241
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• 2006

Seasonal variation of the infection by three species of symbiotic copepods in clam, Tresus keenae was investigated in south coast of Korea. The prevalence and abundance of three symbiotic copepods showed seasonal variation with a peak in winter. Reproduction of the copepods occurs from early autumn to spring as indicated by higher ratio of gravid copepods. The frequency distribution of Lichomolgus inflatus, Pseudomyicola spinosus and Anthessius progectus in their host population could be fitted with negative binominal distribution. Results from the present study suggest that seasonal fluctuation in prevalence, relative density and mean intensity is related to temperature and life history of the symbiotic copepods.

• Parasites, Hosts and Diseases
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• v.31 no.3
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• pp.207-214
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• 1993

This study was conducted to evaluate the current endemicity and the transition mode of the Clonorchis infection in Sanchong-gun Kyongsangnam-do. The areas of investigation, villages and schools surveyed, method and techniques used in this study were the same as in 1984. The egg positive rate of clonorchiasis in the general population of Sanchong-gun was 37.6% out of 837 exanuned persons. In the schoolchildren. the rate was 9.7% out of 145 persons examined. In the Intensity of the infEction among the cases. the mean EPG (Egg Per gram of feces) in the inhabitants and schoolchildren were 3, 310 (male 4, 221, female 1, 978) and 711 tamale 620. female 8331, respectively. Of the inhabitants with clonorchiasis, the cases of light infection (EPG < 1, 000) and moderate infection (1.000 < EPG < 10, 000) were 93.9%. The proportion with experience of eating raw freshwater-fish was 90.5% among the infecters. Out of 138 Inhabitants examined in both 1984 and 1992, the number of the positives by both examinations was 31 (22.5%), positive to negative conversion was 35 (25.4%), negative to positive conversion was 22(15.9%). The present results reveal that there are no chanties of the e99 Positive rate of clonorchiasis among inhabitants in Sanchong and the eating habit of raw freshwater-fish persists there. In this community, the eating habit Is the most important problem to be solved for control of this endemic diease.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.15-20
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• 2013

Urinary bladder squamous cell carcinoma (SCC), one of the most common neoplasms in Egypt, is attributed to chronic urinary infection with Schistosoma haematobium (Schistosomiasis). The proto-oncogene c-KIT, encoding a tyrosine kinase receptor and implicated in the development of a number of human malignancies, has not been studied so far in schistosomal urinary bladder SCCs. We therefore determined immunohistochemical (IHC) expression of c-KIT in paraffin sections from 120 radical cystectomies of SCCs originally obtained from the Pathology Department of Suez Canal University (Ismailia, Egypt). Each slide was evaluated for staining intensity where the staining extent of >10% of cells was considered positive. c-KIT overexpression was detected in 78.3% (94/120) of the patients, the staining extents in the tumor cells were 11-50% and >50% in 40 (42.6%) and 54 (57.4%) respectively. The positive cases had 14.9%, 63.8%, 21.3% as weak, moderate and strong intensity respectively. Patients with positive bilharzial ova had significantly higher c-KIT expression than patients without (95.2% vs. 38.9%, P=0.000). Mutation analysis of exons 9-13 was negative in thirty KIT positive cases. The high rate of positivity in SBSCC was one of the striking findings; However, CD117 may be a potential target for site specific immunotherapy to improve the outcome of this tumor.

• Journal of The Korean Society of Integrative Medicine
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• v.11 no.2
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• pp.141-147
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• 2023

Purpose : This study aimed to find out the effect of aerobic exercise using Bruce protocol on heart rate, oxygen saturation, and blood pressure after recovery from COVID-19 infection. Methods : In this study, 34 students from D University located in J city were targeted, COVID-19 infected group (17 people) and non-COVID-19 non-infected group (17 people). The Bruce protocol using a treadmill was applied to the aerobic exercise of this study. The Bruce protocol has in the first stage of METs 4 (slope 10 %, speed 2.7 km/h). The second stage was METs 5 (slope 12 %, speed 4 km/h), and the third stage was METs 6 (slope 14 %, speed 5.4 km/h). All measurements were measured 3 times and the average value was used. Results : As a result of this study, as a result of comparing heart rate changes according to aerobic exercise using the Bruce protocol. EG group and the CG group increased significantly according to the progressive exercise load (METs 4~5), and in the third stage of the Bruce protocol between groups, The EG group showed a significantly lower heart rate. As a result of comparing changes in oxygen saturation and blood pressure, there was no significant difference between the EG and C groups according to the gradual exercise load. Conclusion : In conclusion, there was no difference between normal and pressure when MET of moderate intensity exercise (4 to 6) was applied to the effect on heart rate, oxygen saturation, and blood pressure in healthy adults who were fully recovered from COVID-19. Secondary side effects may occur when high intensity exercise with a MET of 6 or higher, so it is strongly recommended that hospitals or specialized institutions measure exercise and physical ability according to individual exercise intensity.

• The Journal of the Korea Contents Association
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• v.22 no.5
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• pp.446-455
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• 2022

This study investigated work experience of firefighters and risk factors for their depression during COVID-19 pandemic. We analyzed data of 53,557 firefighters who participated in the online mental health status survey. Data included experiences of COVID-19 infection, experience of COVID-19 response work, fear of social stigma, and anxiety and depression symptoms. Results showed that 45.76% of participants had experience of COVID-19 response work. Emergency job group had the highest percentage of COVID-19 related work and the greater intensity of the work and fear of social stigma than those of other job groups. Hierarchical multiple regression showed that co-workers' infection, COVID-19 related work intensity and fear of social stigma were significantly associated to the severity of depression. The findings in this study demonstrated COVID-19 related work experience can link to the development of depression in firefighters. Effort to reduce COVID-19 related work intensity and fear of social stigma could help prevent depression among firefighters.

• Journal of Bio-Environment Control
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• v.4 no.2
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• pp.240-245
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• 1995

In order to find out the effect of temperature and shading on the growth and major disease infection of Eutrema wasabi Matsum., experiments were at growth chamber condition and field. Plant height, petiole and rhizome of wasabi were obvious decreased with increase the temperature, from which the optimum air temperature for the plant growth were estimated to be 17$^{\circ}C$. The light intensity of the treatment with 75% shading net was favorable to the length of main rhizome, rhizome weight and whole plant weight. Infection ratio of black leg and soft rot were increased at high temperature condition, however their infection ratio were decreased with increase the shading condition.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.23
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• pp.10463-10468
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• 2015

Opisthorchis viverrini (Ov) infection is the major etiological factor for cholangiocarcinoma (CCA), especially in northeast Thailand. We have previously reported significant involvement of PI3K/AKT/PTEN and $Wnt/{\beta}$-catenin in human CCA tissues. The present study, therefore, examined the expression and activation of PI3K/AKT/PTEN and $Wnt/{\beta}$-catenin signaling components during Ov-induced cholangiocarcinogenesis in a hamster animal model. Hamsters were divided into two groups; non-treated and Ov plus NDMA treated. The results of immunohistochemical staining showed an upregulation of PI3K/AKT signaling as determined by elevated expression of the $p85{\alpha}$-regulatory and $p110{\alpha}$-catalytic subunits of PI3K as well as increased expression and activation of AKT during cholangiocarcinogenesis. Interestingly, the staining intensity of activated AKT (p-AKT) increased in the apical regions of the bile ducts and strong staining was detected where the liver fluke resides. Moreover, PTEN, a negative regulator of PI3K/AKT, was suppressed by decreased expression and increased phosphorylation during cholangiocarcinogenesis. We also detected upregulation of $Wnt/{\beta}$-catenin signaling as determined by increased positive staining of Wnt3, Wnt3a, Wnt5a, Wnt7b and ${\beta}$-catenin, corresponded with the period of cholangiocarcinogenesis. Furthermore, nuclear staining of ${\beta}$-catenin was observed in CCA tissues. Our results suggest the liver fluke infection causes chronic inflammatory conditions which lead to upregulation of the PI3K/AKT and $Wnt/{\beta}$-catenin signaling pathways which may drive CCA carcinogenesis. These results provide useful information for drug development, prevention and treatment of CCA.

• Parasites, Hosts and Diseases
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• v.53 no.1
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• pp.51-58
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• 2015

Toxocariasis is a soil-transmitted helminthozoonosis due to infection of humans by larvae of Toxocara canis. The disease could produce cognitive and behavioral disturbances especially in children. Meanwhile, in our modern era, the incidence of immunosuppression has been progressively increasing due to increased incidence of malignancy as well as increased use of immunosuppressive agents. The present study aimed at comparing some of the pathological and immunological alterations in the brain of normal and immunosuppressed mice experimentally infected with T. canis. Therefore, 180 Swiss albino mice were divided into 4 groups including normal (control) group, immunocompetent T. canis-infected group, immunosuppressed group (control), and immunosuppressed infected group. Infected mice were subjected to larval counts in the brain, and the brains from all mice were assessed for histopathological changes, astrogliosis, and IL-5 mRNA expression levels in brain tissues. The results showed that under immunosuppression, there were significant increase in brain larval counts, significant enhancement of reactive gliosis, and significant reduction in IL-5 mRNA expression. All these changes were maximal in the chronic stage of infection. In conclusion, the immunopathological alterations in the brains of infected animals were progressive over time, and were exaggerated under the effect of immunosuppression as did the intensity of cerebral infection.