• Proceedings of the Membrane Society of Korea Conference
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• 2004.05a
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• pp.199-202
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• 2004

Membrane technology is widely employed as a means of producing various qualities of water from surface water, well water, brackish water and seawater. This is also used in industrial wastewater treatment and its recycling process. A large volume of wastewater is generated by the steel industry. Presently, the treated wastewater from the steel industry cannot be recycled, because some of its components cause either direct or indirect problems.(omitted)

• Journal of Korean Society of Industrial and Systems Engineering
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• v.18 no.35
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• pp.131-138
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• 1995

For the purpose of the reduction of tile cost, a production/inventory model including the interference phenomenon was developed. By investigating the cause and the characteristics of the direct/indirect cost due to the interference phenomenon, a strategy for suitable production was developed. The developed model was quantitatively validated using an existing-EPQ model and the SIMAN package was used to simulate and animate the model. Consequently, it was presented that the total operating cost of the system could be decreased with tile proposed model.

• Journal of the Korean Home Economics Association
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• v.39 no.9
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• pp.137-152
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• 2001

On the basis of the equity theory, as the couple perceives their relationship is equitable, they tend to make decisions jointly and are satisfied with their family lives. Therefore this study is aimed to identify the relationship among perception of equity, decision-making styles and family life satisfaction in dual-career couples. As a result of analyzing the cause-effect relationship, it shows that many socioeconomic$.$psychological variables have direct indirect impact on family life satisfaction through medium factor, so this study proves the application of the cause-effect modes. However the influence of the perception of equity of wives were higher than husbands.

• Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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• 2004.11a
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• pp.223-227
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• 2004

False-tripping of MCCB(Molded Case Circuit Breaker) and ELB(Earth Leakage Circuit Breaker), using to protect overload and ground-fault accidents in power system raise direct and indirect losses like as information loss, facilities damage, slipup of goods production in industry place. Cause of false-tipping of MCCB and ELB is various and cause analysis of false-tripping is mostly made up by inference because trip is not reappeared. This paper investigated and analyzed causes and influences of false-tripping of MCCB and ELB by making up a question to safety managers of two hundred and eighteen electrical facilities for private use. Also, the necessity of experimental study on the effect of harmonics on false-tipping of MCCB and ELB was presented.

• KIEAE Journal
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• v.12 no.2
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• pp.77-82
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• 2012

Data mining is to discover problems in the large amounts of data. Also, data mining trying to find the cause of the problem and the structure. Building energy consumption patterns, the amount of data is infinite. Also, the patterns have a lot of direct and indirect effects. Discussion is needed about the correlation. This work looking for the cause of energy consumption. As a result, energy management can find out the issue. Building energy analysis utilizing data mining techniques to predict energy consumption. And the results are as follows: 1) Using data mining technique, We classified complicated data to several patterns and gained meaningful informations from them. 2) Using cluster analysis, We classified building energy consumption data of residents and analyzed characters of patterns.

• Transactions of the Korean Society of Automotive Engineers
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• v.22 no.2
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• pp.148-155
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• 2014

Most truck fires breaking out on the expressway are directly damaged by fire destruction of truck and freight and many of them cause indirect damage such as serious traffic holdups. This study analyzed the fire causes and their liability of the 25-ton truck fire breaking out during expressway driving. This truck fire was caused by manufacturing defect of return spring of a braking system. The fire liability rested with a maker(manufacturer) rather than a truck owner or a driver and the maker also bore fire liability based on the Product Liability Law.

• Journal of Acupuncture Research
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• v.23 no.4
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• pp.1-14
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• 2006

Objectives : We implemented the Moxa-Extract Moxibustion Method in order to improve the conventional moxibustion therapy. This method is aimed to eliminate burning wounds and smoke, which are the defects of conventional moxibustion therapy. And we performed to verify the efficiency by comparing the Moxa-Extract Moxibustion Method with the conventional Indirect Moxibustion Method. We measured the body heat and the lasting time of blood circulation improveent using thermography. We implemented the Moxa-Extract Moxibustion Method in order to improve the conventional moxibustion therapy. This method is aimed to eliminate burning wounds and smoke, which are the defects of conventional moxibustion therapy. And we performed to verify the efficiency by comparing the Moxa-Extract Moxibustion Method with the conventional Indirect Moxibustion Method. We measured the body heat and the lasting time of blood circulation improvement using thermography. Methods : The moxibustion therapy has two kinds of effects: The formers are pharmacological effects of the Moxa's vasodilators and antioxidants. The latters are thermal effects which cause improvement of the blood circulation. To remove the demerits without omission of above therapeutic effects, we extracted the vasodilators and antioxidant compounds from the Moxa-CH2Cl2 fraction Moxa-EtOA and composed the moxibustion kit with (Ba0.8 Sr0.2)0.996 Y0.004 TiO2 + 0.5WT SiO2% positive Temperature Coefficients Thermistor. The experimental demonstrations have been made by the stimulating the spot which is CV4(Kwan-Won), CV8(Shin-Guel), CV12(Jung-Wan) acupuncture points of the conception vessel meridian(CV). And stimulating time was one hour. We divided the subjects into 5 groups such as no stimulation group, conventional Indirect Moxibustion group, only Moxa-Extract stimulation group, only heat stimulation group, and Moxa-Extract Moxibustion group. In the different cases, we have measured the body heat in pre-stimulation, just after stimulation, 2 hours after, and 4 hours after. Results : he body heats of the group who were stimulated by the Moxa-Extract Moxibustion method were increased by over the $2^{\circ}C$. And the body heats of the group who were stimulated by the Indirect Moxibustion Method were increased by average the $1^{\circ}C$. We have evaluated that the Moxa-Extract Moxibustion Method is improvement on the Indirect Moxibustion Method by the increasing rate is 200% and increasing time is 150% with the body heat of the abdominal region. Conclusion : We have implemented the Moxa-Extract Moxibustion Method and evaluated the efficiency of the Moxa-Extract Moxibustion Method comparing with the Indirect Moxibustion Method.

• KIPS Transactions on Software and Data Engineering
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• v.6 no.9
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• pp.419-428
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• 2017

In an embedded system, modules exchange data by interacting among themselves. Exchanging erroneous resource data among modules may lead to execution errors. The interacting resources produce dependencies between the two modules where any change of the resources by one module affects the functionality of another module. Several investigations of the embedded systems show that interaction faults between the modules are one of the major cause of critical software failure. Therefore, interaction testing is an essential phase for reducing the interaction faults and minimizing the risk. The direct and indirect interactions between the modules generate interaction faults. The direct interaction is the explicit call relation between the modules, and the indirect interaction is the remaining relation that is made underneath the interface that possesses data dependence relationship with resources. In this paper, we investigate the errors that are based on the indirect interaction between modules and introduce a new test criterion for identifying the errors that are undetectable by existing approaches at the integration level. We propose a novel approach for generating the interaction model using the indirect interaction pattern and design test criteria that are based on different interaction errors to generate test cases. Finally, we use the fault injection technique to evaluate the feasibility and effectiveness of our approach.

• Korean Journal of Clinical Pharmacy
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• v.29 no.4
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• pp.223-230
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• 2019

Background: Small-molecule tyrosine kinase inhibitors (TKIs) have had major impacts on anticancer therapy by targeting the catalytic activities of dysregulated tyrosine kinases. TKIs have not presented traditional toxicities; however, some serious adverse effects, including hepatotoxicity, have been documented in clinical trials and post-marketing surveillance. Although TKI-induced hepatotoxicity can cause severe clinical complications in patients, the underlying mechanism is still unclear. Methods: Studies on TKI-induced hepatotoxicity were identified by Pubmed search, and relevant articles were reviewed. Results: Immunoallergic reaction, cytochrome P (CYP) 450 polymorphisms, and formation of reactive metabolites are under consideration as mechanisms of TKI-induced hepatotoxicity. Host protein-drug metabolite conjugates are recognized as antigens by class II major histocompatibility complexes and are believed to cause liver injuries. Polymorphisms in CYP, which influences TKI metabolism, can slow TKI metabolism and may induce development of hepatotoxicity. The formation of reactive metabolites during drug metabolism can induce hepatotoxicity by directly causing cytotoxicity, leading to cell dysfunction, and indirect toxicity by mediating secondary immune reactions. Concurrent use of various medications with TKI can also cause hepatotoxicity by affecting drug transporter or enzyme activities. Conclusion: Periodic monitoring of patients taking TKIs and risk/benefit reassessments though post marketing surveillance are necessary to prevent hepatotoxicity.

• Industrial Engineering and Management Systems
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• v.14 no.1
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• pp.58-72
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• 2015

A primary concern of national R&D plans is to encourage technological development in private firms and research institutes. For effective R&D planning and program support, it is necessary to assess technological impacts that may exist both directly and indirectly among technology areas within the whole technology system; however, previous studies analyze only direct impacts among technologies, failing to capture both direct and indirect impacts. Therefore, this study proposes an approach based on decision-making trial and evaluation laboratory (DEMATEL) to identifying specific characteristics of technology areas, such as technological impact and degree of cause or effect (DCE). The method employs patent co-classification analysis to construct a technological knowledge flow matrix. Next, to capture both direct and indirect effects among technology areas, it incorporates the modified DEMATEL process into patent analysis. The method helps analysts assess the technological impact and DCE of technology areas, and observe their evolving trajectories over time, thereby identifying relevant technological implications. This study presents a case study using Korean patents registered during 2003-2012. We expect our analysis results to be helpful input for R&D planning, as well as the suggested approach to be incorporated into processes for formulating national R&D plans.