• Korean Journal of Soil Science and Fertilizer
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• v.50 no.3
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• pp.195-202
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• 2017

The volcanic ash soils from the Jeju province have low available phosphate because of the high phosphate fixing power of the soils. Phosphorus fertilizerwas dressed after cultivating green manure crops and before cultivating potatoes in order to investigate potato yields, the available phosphate contents, and phosphorus balance in the soils. Green manure crops cultivated in this study were hairy vetch alone and hairy vetch and rye. During potato cultivation, four treatments were conducted in the experiments; NF (non fertilizer), P fertilizer ($N-P-K=0-25-0kg\;10a^{-1}$), NK fertilizer ($N-P-K=18-0-19kg\;10a^{-1}$), and NPK fertilizer ($N-P-K=18-25-19kg\;10a^{-1}$). There were no differences in the yields of potato stem and tuber from the cultivation plots of different green manure crops. However, in the plots with single-sown hairy vetch and mixed-sown hairy vetch and rye, the yields of potato stem and tuber were higher in the P fertilizer plot than in NF plot. The yield of tuber among the treatments with mixed-sown hairy vetch and rye was the highest in the NPK fertilizer plot. The available phosphate content in soils initially increased with time in all plots, but began to decrease gradually after Oct. 18. The available phosphate contents were high in the plots for phosphate fertilization, and the difference in available phosphate content between non-phosphorus fertilizer plots and phosphorus fertilizer plots increased with time. In the single-sown hairy vetch and mixed-sown hairy vetch and rye plot, the phosphorus balances in NF plot and NK fertilizer plot were very low, while those in the P fertilizer plot and NPK fertilizer plot were high. In conclusion, available phosphate contents in soil and the potato yields were increased by phosphorus fertilization when potatoes planted after cultivating hairy vetch and rye together, compared to hairy vetch alone.

• Journal of the Korea Concrete Institute
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• v.17 no.5 s.89
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• pp.703-708
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• 2005

The effects of polymer-cement ratio and antifoamer content on the setting time and durability of high-fluidity polymer-modified mortars using redispersible polymer powder are examined. As the result, the setting time of the polymer-modified mortars using redispersible polymer powder tends to be delayed with increasing polymer-cement ratio, regardless of the antifoamer content. The water absorption, chloride ion penetration depth and carbonation depth of the high-fluidity polymer-modified mortars using redispersible polymer powder decrease with increasing polymer-cement ratio and antifoamer content. The resistance of freezing and thawing and chemicals improvement is attributed to the improved bond between cement hydrates and aggregates because of the incorporation of redispersible polymer powder

• Convergence Security Journal
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• v.7 no.1
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• pp.19-27
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• 2007

Detecting unknown threats is a paradox ; how do you detect a threat if it is not known to exist? The answer is that unknown threat detection is the process of making a previously unknown threat identifiable in the shortest possible time frame. This paper examines the possibility of creating an unknown threat detection mechanism that security experts can use for developing a flexible protection system for networks. A system that allows the detection of unknown threats through monitoring system and the incorporation of dynamic and flexible logics with situational knowledge is described as well as the mechanisms used to develop such a system is illustrated. The system not only allows the detection of new threats but does so in a fast and efficient manner to increase the available time for responding to these threats.

• Asian-Australasian Journal of Animal Sciences
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• v.27 no.3
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• pp.422-430
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• 2014

Pasture-based automatic milking systems (AMS) require cow traffic to enable cows to be milked. The interval between milkings can be manipulated by strategically allocating pasture. The current experiment investigated the effect of replacing an allocation of grazed pasture with grazed soybean (Glycine max) with the hypothesis that incorporating soybean would increase voluntary cow traffic and milk production. One hundred and eighty mixed age, primiparous and multiparous Holstein-Friesian/Illawarra cows were randomly assigned to two treatment groups (n = 90/group) with a $2{\times}2$ Latin square design. Each group was either offered treatments of kikuyu grass (Pennisetum clandestinum Hoach ex Chiov.) pasture (pasture) or soybean from 0900 h to 1500 h during the experimental period which consisted of 2 periods of 3 days following 5 days of training and adaptation in each period with groups crossing over treatments after the first period. The number of cows trafficking to each treatment was similar together with milk yield (mean ${\approx}18$ L/cow/d) in this experiment. For the cows that arrived at soybean or pasture there were significant differences in their behaviour and consequently the number of cows exiting each treatment paddock. There was greater cow traffic (more cows and sooner) exiting pasture allocations. Cows that arrived at soybean stayed on the allocation for 25% more time and ate more forage (8.5 kg/cow/d/allocation) relative to pasture (4.7 kg/cow/d/allocation). Pasture cows predominantly replaced eating time with rumination. These findings suggest that replacing pasture with alternative grazeable forages provides no additional incentive to increase voluntary cow traffic to an allocation of feed in AMS. This work highlights the opportunity to increase forage intakes in AMS through the incorporation of alternative forages.

• Korean Journal of Materials Research
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• v.8 no.3
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• pp.229-237
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• 1998

We grew the hexagonal GaN films on (100) Si and (00.1) sapphire substrates in the temperature range of $300~730^{\circ}C$ by the direct reaction between thermally ionized N-source and thermally evaporated Ga-source. The GaN growth rates are increased at the initial stage of GaN formation and it was saturated to some values by the coalescence of each crystallites. The oxygen signal was observed in XPS spectra for all the GaN films grown in this work, especially low- temperature grown GaN film may due to incorporation of the residual oxygen in the growth chamber. The surface of low-temperature and shorter time grown films covered only Ga-droplets. however, with increasing the both substrate temperature and the growth time GaN is growth to crystallites. and coalescence to ring-type crystallites. With sufficient supply of N-source, they were changed to platelets. In the PL spectrum measured at 20 K, we observed the impurity related emission at 3.32eV and 3.38eV.

• Biomolecules & Therapeutics
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• v.25 no.6
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• pp.648-658
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• 2017

7-O-Succinyl macrolactin A (SMA) exerts several pharmacological effects including anti-bacterial, anti-inflammation, and anti-cancer activities. Recently, SMA has been extensively evaluated as an anti-cancer drug. Thus, the objectives of the present study were to characterise the pharmacokinetics of SMA via both non-compartmental and compartmental analysis in mice, rats, and dogs, and to derive an appropriate first-in-man dose based on allometric scaling of the animal data. The time courses of plasma SMA concentrations after intravenous administration to rats and dogs were analysed retrospectively, as were data collected after intraperitoneal SMA injection in mice. Pharmacokinetic parameters were estimated via both noncompartmental and compartmental analysis, and were correlated with body weight and/or the potential maximum life-span. The clearance and distribution volume of SMA in humans were predicted, and a first-in-man dose proposed. A two-compartment model best described the time courses of SMA plasma concentrations after a saturation elimination process was applied to fit the dataset obtained from rats. Incorporation of the maximum potential life-span during allometric scaling was required to improve the estimation of human clearance. The SMA clearance and the distribution volume in the steady state, in a 70-kg adult male, were estimated to be 30.6 L/h and 19.5 L, respectively. To meet the area under the curve (AUC) required for anti-tumour activity, a dose of 100 mg (~1.5 mg/kg) was finally proposed as the first dose for a 70-kg human. Although toxicological profiles derived from non-clinical studies must be considered before any final decision is made, our work will facilitate clinical studies on SMA.

• Korean Journal of Ecology and Environment
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• v.38 no.spc
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• pp.31-38
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• 2005

Diel change in urea decomposition activity of epiphytic algae on Phragmites stems and phytoplankton in a shallow littoral reed zone in the south basin of Lake Biwa was investigated with an in situ technique using $^{14}C$-labelled urea. The daily rates of urea decomposition (sum of urea carbon incorporation rate and $CO_2$ liberation rate) by epiphytic and planktonic algae were calculated as 180 ${\mu}$ mole urea surface shoot area $m^{-2}\;day^{-1}$ and 210 ${\mu}$ mole urea $m^{-3}\;day^{-1}$. The chlorophyll a specific urea decomposition rates of epiphytic and planktonic algae were 4.7 to 6.4 and 4.4 to 6.2 ${\mu}$ mole urea mg chl. $a^{-1}$ incubation $time^{-1}$ in daytime and 4.2 to 5.7 and 2.4 to 3.5 ${\mu}$ mole urea mg chl. $a^{-1}\;time^{-1}$ in nighttime, respectively. High values were obtained during 12:00 ${\sim}$ 18:00 and low values during 00:00 ${\sim}$ 06:00 for both epiphytic and planktonic algal communities. A clear diel periodicity in the urea decomposing activity of the planktonic algae was observed. The activity of the epiphytic algae, on the other hand, showed no destinctive variation during a day. The present results indicate that epiphytic algae are one of the significant urea decomposers in a reed zone, and that the diel patterns are quite difference between both algal communities.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.16 no.1
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• pp.67-74
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• 1998

This paper performed terrain analysis using DTM(digital terrain model) with TIN/ GRID structure on PC environment. Contour layer from 1:5,000 scale map was used to produce DTM. DTHs were produced with and without considering breakline for each data structure. Processing time, file size, mean elevation and standard variation were analyzed for each DTM. slope map, aspect map were analyzed for grid structure with consideration of TEX>$5\times{5m},\;l0\times{10m},\;15\times{15m},\;l0\times{30m},\;45\times{45m},\;60\times{60m}$ cell size respectively. The results suggest following; The incorporation of breakline does improve mapping accuracy for highly disturbed landscape, Mean elevation doesn't increase as the grid size increases, while processing time, storage room is significantly lessened. Thus, the optimal grid size must be determined in advance for efficient application. slope decreases, while aspect increases as grid size is increasing.

• Parasites, Hosts and Diseases
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• v.47 no.2
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• pp.139-144
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• 2009

The aim of the present study was to investigate antimalarial drug pressure resulting from the clinical use of different antimalarials in Thailand. The phenotypic diversity of the susceptibility profiles of antimalarials, i.e., chloroquine (CQ), quinine (QN), mefloquine (MQ), and artesunate (ARS) in Plasmodium falciparum isolates collected during the period from 1988 to 2003 were studied. P. falciparum isolates from infected patients were collected from the Thai-Cambodian border area at different time periods (1988-1989, 1991-1992, and 2003), during which 3 different patterns of drug use had been implemented: MQ+sulphadoxine (S)+pyrimethamine (P), MQ alone and MQ+ARS, respectively. The in vitro drug susceptibilities were investigated using a method based on the incorporation of $[^3H]$ hypoxanthine. A total of 50 isolates were tested for susceptibilities to CQ, QN, MQ, and ARS. Of these isolates, 19, 16, and 15 were adapted during the periods 1988-1989, 1991-1993, and 2003, respectively. P. falciparum isolates collected during the 3 periods were resistant to CQ. Sensitivities to MQ declined from 1988 to 2003. In contrast, the parasite was sensitive to QN, and similar sensitivity profile patterns were observed during the 3 time periods. There was a significantly positive but weak correlation between the $IC_{50}$ values of CQ and QN, as well as between the $IC_{50}$, values of QN and MQ. Drug pressure has impact on sensitivity of P. falciparum to MQ. A combination therapy of MQ and ARS is being applied to reduce the parasite resistance, and also increasing the efficacy of the drug.

• Journal of the Korean institute of surface engineering
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• v.44 no.4
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• pp.131-136
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• 2011

A kinetic study has been made for the growth of nanocrystalline diamond (NCD) particles to a continuous thin film on silicon substrate in a microwave plasma chemical vapor deposition reactor. Parameters of deposition have been microwave power of 1.2 kW, the chamber pressure of 110 Torr, and the Ar/$CH_4$ ratio of 200/2 sccm. The deposition has been carried out at temperatures in the range of $400\sim700^{\circ}C$ for the times of 0.5~16 h. It has been revealed that a continuous diamond film evolves from the growth and coalescence of diamond crystallites (or particles), which have been heterogeneously nucleated at the previously scratched sites. The diamond particles grow following an $h^2$ = k't relationship, where h is the height of particles, k' is the particle growth rate constant, and t is the deposition time. The k' values at the different deposition temperatures satisfy an Arrhenius equation with the apparent activation energy of 4.37 kcal/mol or 0.19 eV/ atom. The rate limiting step should be the diffusion of carbon species over the Si substrate surface. The growth of diamond film thickness (H) shows an H = kt relationship with deposition time, t. The film growth rate constant, k, values at the different deposition temperatures show another Arrhenius-type expression with the apparent activation energy of 3.89 kcal/mol or 0.17 eV/atom. In this case, the rate limiting step might be the incorporation reaction of carbon species from the plasma on the film surface.