• Journal of Plant Biotechnology
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• v.44 no.2
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• pp.107-114
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• 2017

Implementation of crop improvement programs relies on genetic diversity. To overcome the limited occurrence of natural mutations, researchers and breeders applied diverse methods, ranging from conventional crossing to classical bio-technologies. Earlier generations of knockout and gain-of-function technologies often result in incomplete gene disruption or random insertions of transgenes into plant genomes. The newly developed editing tool, CRISPR/Cas9 system, not only provides a powerful platform to efficiently modify target traits, but also broadens the scope and prospects of genome editing. Customized Cas9/guide RNA (gRNA) systems suitable for efficient genomic modification of mammalian cells or plants have been reported. Following successful demonstration of this technology in mammalian cells, CRISPR/Cas9 was successfully adapted in plants, and accumulating evidence of its feasibility has been reported in model plants and major crops. Recently, a modified version of CRISPR/Cas9 with added novel functions has been developed that enables programmable direct irreversible conversion of a target DNA base. In this review, we summarized the milestone applications of CRISPR/Cas9 in plants with a focus on major crops. We also present the implications of an improved version of this technology in the current plant breeding programs.

• Journal of Families and Better Life
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• v.30 no.1
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• pp.77-88
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• 2012

This study has developed on Virtues Project program, which enhances parent communication abilities. The purpose of this study is to verify the improvement on parent communication skills after taking a program. To obtain effective children educational direction, we have offered assistance to the parents that understanding the importance of the parental instruction, improvement of the relationship between parents and children. To enhance the parent communication ability, this program is consisted of five virtue strategies, structured activity programs and various self-examination for attending parents to the program rather than listening the lecture. This program is consists of six session with two hours each session for six weeks. I have studied 26 subjects and they were divided into experiment group and control group. According to this study, this program works on improving parent communication skills. Namely, experiment group showed significant enhancement of communication abilities compared to that of control group.

• Korean Journal of Applied Biomechanics
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• v.28 no.2
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• pp.119-125
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• 2018

Objective: The purpose of this study was to compare the effect of different 12-week exercise programs for posture correction on postural alignment in elderly women. Method: The study included 36 elderly women who were randomly divided into 3 groups: Group A (core exercise, n=12), Group B (combined exercise, n=12), and Group C (Pilates exercise, n=12). Postural alignment was measured using 6 variables in frontal and sagittal planes. Two-way mixed analysis of variance was used to compare the effect of exercise program types on postural alignment and a paired t-test was used to compare differences in postural alignment after exercise. Results: The core exercise group showed statistically significant improvement (p<.05) in multiple upper and lower body postural alignment measurements. The combined exercise and Pilates exercise groups showed statistically significant improvement (p<.05) in upper body measurements alone. Conclusion: Core exercise, combined exercise, and Pilates exercise improved postural alignment in elderly woman through improvement in muscle strength and ligament flexibility around the spine and pelvis.

• Journal of the Architectural Institute of Korea Planning & Design
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• v.35 no.5
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• pp.31-40
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• 2019

The purpose of this study is to propose policy implications of youth facilities that will be expanded by analysing at the current status of youth facilities in Seoul. The study was conducted as a process of improvement directions through prior researches and analysis of policy, survey of cases and analysis of status. First, the appearance background and status of youth facilities were analyzed for the study. It also looked at research institutes and Seoul Metro Government's policies and systems. Second, the space composition of 10 youth facilities operated by the Seoul Metropolitan Government was analyzed according to local characteristics, programs and policies. Third, based on this, the policy implications of youth facilities were derived. As a result of the study, the following results were derived : First, the need to link youth facilities with policies to "live" solutions, secondly, DB of information and connection to youth facilities and jobs and thirdly, connection with major public institutions and facilities to promote active use, and finally, development of space provision and support systems and programs considering characteristics of local governments.

• Quality Improvement in Health Care
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• v.8 no.2
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• pp.146-159
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• 2001

Background : To propose effective strategies for successful implementation of QI in health care institutions, by identifying facilitating factors and barriers to conducting QI programs. Methods : In order to examine empirical evidence on the success factors or barriers to QI implementation in hospitals, a literature study was performed on the basis of MEDLINE search. Among the identified literature. 13 provided reliable findings and basis comprehensive discussion on this issue and thus were selected for in-depth analysis. A mailed questionnaire survey was conducted for hospital CEOs and QI directors of hospitals with 400 beds or greater to investigate what attributes of their organizations they perceived as success factors or obstacles to QI implementation. Result : The analysis of selected literature and survey results presented that the primary factors considered to be most important as successful implementation of QI were: strong support from hospital CEOs, setting higher priority for QI activities, continuous and persistent efforts in QI activities, and active participation of clinical staffs. The barriers identified in this study were : the lack of orientation and understanding of QI concepts, low level of interest and participation of physician in QI programs, the lack of evaluation and rewarding system for QI activities. Conclusion : By identifying factors that affect facilitation of QI, the study results will be of great use for either institutions being in the early stage of evolving QI or those looking for better strategies to achieve more active and persistent QI implementation in their institutions.

• Journal of KIISE:Software and Applications
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• v.32 no.8
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• pp.795-807
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• 2005

The classical approaches for computing Live Variable Analysis(LVA) use iterative algorithms across the entire programs based on the Data Flow Analysis framework. In case of Zephyr compiler, average execution time of LVA takes $7\%$ of the compilation time for the benchmark programs. The classical LVA algorithm has many aspects for improvement. The iterative algorithm for LVA scans useless basic blocks and calculates large sets of variables repeatedly. We propose the improvement of Iterative algorithm for LVA based on used variables' upward movement. Our algorithm produces the same result as the previous iterative algorithm. It is based on use-def chain. Reordering of applying the flow equation in DFA reduces the number of visiting basic blocks and redundant flow equation executions, which improves overall processing time. Experimental results say that our algorithm ran reduce $36.4\%\;of\;LVA\;execution\;time\;and\;2.6\%$ of overall computation time in Zephyr compiler with benchmark programs.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.32 no.3
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• pp.59-70
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• 2009

This study is the result of meta evaluation for the self evaluation of defense R&D programs in Korea by using meta evaluating indicators. The overall meta evaluation result of defense R&D programs gained 74.3 points out of 100, so it was evaluated as 'Good'. But it demonstrated that further improvement for overall system of defense R&D programs evaluation is required. And especially, it demonstrated that more alternatives are necessary in order to improve the utilizations and the feedbacks of evaluation results. The evaluation context component gained 80.2 points out of 100, so it was evaluated as 'Very Good'. The evaluation input component gained 73.1 points out of 100, so it was evaluated as 'Good'. The evaluation process component gained 74.8 points out of 100, so it was evaluated as 'Good'. And the evaluation outcome component gained 69.0 points out of 100, so it was evaluated as 'Good'. Basic model of meta evaluation was derived from the literature review and brain storming. And this meta evaluation model was determined by adopting the result of experts who performed evaluations for defense R&D programs in recent years. The reliability of components and items was verified by Cronbach's a coefficient. It was over 0.6 in evaluation components and items. And the reliability of evaluation context was 0.877, that of evaluation input was 0.755, that of evaluation process was 0.755, that of evaluation output was 0.755 respectively. From the analysis, it is attempted to identify possible problems and to find out the ways of improvements related to the self evaluation system of defense R&D programs. The ultimate objective of this study is to manage the programs effectively and improve the reliability and the objectiveness of the defense R&D programs.

• Journal of Korean Society of Archives and Records Management
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• v.10 no.1
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• pp.141-167
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• 2010

The goal of this study is to suggest a scheme to vitalize the National Archives of Korea's education programs for children. For this we researched the cases in Korea and abroad operating education programs for children actively. Through analysis we suggested a course of improvement to vitalize the National Archives of Korea's education programs, policy, organization, staff for children. For an area of policy we suggested a stipulation of education program and an exclusive organization and staff placement for an area of organization and staff, an education program which is different from other cultural organization for a program.

• Journal of the Korean BIBLIA Society for library and Information Science
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• v.21 no.1
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• pp.31-42
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• 2010

To expand the cultural function of public libraries is a requisite for satisfying cultural needs and meet residents' diverse requirements of cultural welfare due to the improved level of income and the increased amount of leisure time. The purpose of this study is to conduct researches on the actual state of cultural programs operated by public libraries in Jeju Island and on cultural program users' satisfaction at public libraries, along with a survey with those in charge of the cultural programs to find out problems with operation of the programs and suggest localization and improvement of the cultural programs at public libraries in Jeju Island.

• The Journal of the Society of Korean Medicine Diagnostics
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• v.10 no.1
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• pp.98-108
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• 2006

Background and Purpose: The Han(cold)-Yol(heat) patternization is one of the most usually used diagnostic methods in oriental medicine. This is studies for compensating questionnaries for Han-Yol that were made by Sook-Kyeng Kim. Methods: Questionnaries for Yol should be useful for clinical examination. So symptoms being chosen for questionnaries are based on Donguibogam that is clifnical textbook and 46 items are developed. By delphi panel and statistical analysis Items of questionnaries are choosen. Resultset: By delphi panel and statistical analysis 8 Items of questionnaries are choosen. Conclusion: Further research is necessary for improvement reliabilities and validities of the questionnaires for Yol pattemization.