• Title/Summary/Keyword: ikki

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Effects of BojungIkkiTang-Gamybang on Protective of Cell Death and Anti-Oxidative in C6 Glioma Cell (보중익기탕가미방(補中益氣湯加味方)이 신경교세포의 세포사멸보호 및 항산화에 미치는 영향)

  • Hwang, Gui-Seong;Kim, Hyung-Woo;Choi, Chan-Hun;Jeong, Hyun-Woo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.3
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    • pp.401-409
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    • 2010
  • This study was designed to investigate the effects of BojungIkkiTang-Gamybang freeze dried powder (BITG) on proliferauion, protective of cell death induced by chemicals such as paraquat, hydrogen peroxide etc and anti-oxidative effects in C6 glioma cells. In our results, BITC accelerated proliferation rates of C6 cells in vitro. In addition, protective effects on cell death induced by paraquat and hydrogen peroxide. And, BITC did not have effects on SOD and total glutathione activities, but decresed malone dialdehyde activity. In conclusion, these results suggest the possibility of BojungIkkiTang-Gamybang to protect brain cell or neuronal cell from damage induced by oxidative stress. And also suggest that related mechanisms are involved in malone dialdehyde activity.

Inhibiting and Repairing Effects of Bojung-ikki-tang Gamibang on Cyclophosphamide induced Bone Marrow Injuries in Rats (보중익기탕가미방(補中益氣湯加味方)이 cyclophosphamide 투여로 인한 골수손상의 억제 및 회복에 미치는 영향)

  • Ko, Heung;Kim, Dong-Woo
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.3
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    • pp.736-742
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    • 2005
  • This study was carried out to investigate the inhibiting and repairing effects of Bojung-ikki-tang Gamibang(BI-G) on the bone marrow injuries in rats. Bone marrow injury was induced by a single intraperitoneal injection of cyclophosphamide(CP)(150mg/kg). In experiment I, designed for inhibiting effect, extract of BI-G(80mg) was administrated from pre-5 days to post-5 days of CP injection. In experiment II, designed for repairing effect, extract of BI-G(80mg) was administrated after 5 days to 12 days of CP injection. Hematological and histopathological examinations were performed at 5 days after CP injection in experiment I, and at 12 days after CP injection in experiment II. In experiment I, the results were as follows ; RBC(${\times}10^6/{\mu}l$) of BI-G treated group$(8.39{\pm}0.84)$ was increased significantly compared with control group$(7.52{\pm}7.67)$. Hemoglobin(g/dl) of BI-G treated group$(13.76{\pm}1.20)$ was increased significantly compared with control group$(12.24{\pm}1.11)$. WBC(${\times}10^3/{\mu}l$) of BI-G treated group$(1.75{\pm}0.41)$ was increased significantly compared with control group$(0.55{\pm}0.17)$. Necrotic changes of myeloid cells of BI-G treated group were less severe than those of control group. Histopathologically, distention of sinus and edematous changes of bone marrow of BI-G treated group were alleviated compared with those of control group. In experiment II, the results were as follows ; WBC(${\times}10^3/{\mu}l$) of BI-G treated group(4.27 0.94) was increased significantly compared with control group$(3.02{\pm}0.79)$. Hemoglobin(g/dl) of BI-G treated group$(12.61{\pm}0.85)$ was increased significantly compared with control group$(11.49{\pm}0.74)$. Platelets(${\times}10^3/{\mu}l$) of BI-G treated group$(1885{\pm}133)$ was increased significantly compared with control group$(1616{\pm}251)$. These results indicated that Bojung-ikki-tang Gamibang has the inhibiting and repairing effects on the cyclophosphamide-induced bone marrow injuries in rats.

RESEARCH FOR BOND STRESS-RELATIVE SLIP RELATIONSHIP (부착응력-상대슬립 관계에 대한 연구)

  • 고원준;김진호;서봉원;박선규
    • Proceedings of the Korea Concrete Institute Conference
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    • 2002.05a
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    • pp.221-226
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    • 2002
  • This paper deals with the estimation of the bond stress based on experimental data that were tensed by axial force on both sides. It is certificated that the concrete stress condition clearly affects the bond-slip relationship. The proposed method utilizes the conventional bond-slip theories as well as the characteristics of deformed reinforcement and concrete cross-sectional area. An analytical equation for the estimation of the bond stress is formulated as the function of non-dimensional factors (e.g. bond stress, relative slip, etc.). The validity, accuracy and efficiency of the proposed method are established by comparing the analytical results with the experimental data of Ikki (1996, 1999) and the representative bond stress equations of Shima (1987). The analytical results presented in this paper indicate that the proposed method can be effectively estimated the bond stress-relative slip relationship.

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The Estimation and Comparison of Flexural Crack Width Considering Bonding Characteristics in Reinforced Concrete Members (부착특성을 고려한 철근콘크리트 부재의 휨 균열폭 산정 및 비교)

  • Ko, Won-Jun;Min, Byung-Chul;Park, Sun-Kyu
    • Journal of the Korea Concrete Institute
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    • v.18 no.5 s.95
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    • pp.579-588
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    • 2006
  • In recent years, the availability of high-strength reinforcing and prestressing steels leads us to build economically and efficiently designed concrete structural members. One of critical problems faced to the structural engineers dealing with these types of structural member is controls of crack width that is used as a criterion for the serviceability in the limit state design. Especially, flexural cracking must be controlled to secure the structural safety and to improve the durability as well as serviceability of the load carving members. The proposed method utilizes the results of pure tension test in which tensile loads are applied both side of specimen, done by Ikki. The bond characteristics of deformed reinforcing bar under pure tension is considered by the area of concrete and rib area. The results of proposed method are compared with the test data and the results show that the proposed method can take into account the dimensions, variation of sectional properties, and direction of reinforcing and gives more accurate maximum bond stress and corresponding relative slip than the existing methods. the characteristics of bonding is considered by using dimensionless slip magnitude and effective reinforcement ratio. The validity of the proposed equation is verified by test experimental data.

Comparison Study on the Make-up Cultures between the Ching dynasty in China and the Edo Age in Japan based on their Aesthetic Consciousness (중국(中國) 청(淸) 왕조시대(王朝時代)와 일본(日本) 강호시대(江戶時代)의 미의식(美意識)에 따른 화장문화(化粧文化) 비교 연구)

  • Ahn, Hyun-soon;Koh, Jung-min
    • Cross-Cultural Studies
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    • v.27
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    • pp.59-79
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    • 2012
  • China and Japan are geographically close and the two countries had shared the Chinese Character Culture and the thoughts of Confucianism, Buddhism and Taoism since the ancient age. They also actively exchanged culture in various areas. Some cultural exchanges had been caused by surrounding environment and culture had been introduced to other country in a natural way; while some cultural exchanges had been forcibly introduced through artificial process. It is believed that such cultural phenomenon must have had impact on the make-up cultures of the two countries and it was assumed that there must have been commons and differences in the make-up cultures of the two countries. This study explored the historical background of the Ching dynasty of China and the Edo Age in Japan, which are in the same time frame, and studied the aesthetic consciousness of the two countries at the time. Then the make-up style of ladies in the two countries had been studied to find out how their aesthetic consciousnesses had been expressed in the make-ups of the two countries. Then the commons and differences in make-up skills between the two countries had been identified. According to the study results, the main stream of aesthetics during the Ching dynasty in China can be classified into Confucianism aesthetics and Taoism aesthetics. On the other hand, the main stream of aesthetics during the Edo Age in Japan can be classified into "mitate(見立)", "ikki(いき)" and "garumi(かるみ). The skin care in the make-up culture of Ching dynasty in China was based on "rouge (?脂, yanzhi)" and "powder(粉, fen)". The Ching ladies loved the make-up style using rouge. It had been same both in the high society and common people. The eyebrow care was delicate and curved so that the feminine beauty with elegant spirit could be emphasized. The lips had been expressed to be smaller and the ladies tried to express elegance and reliability, rather than frail and tender feminine image. The skin care in the make-up culture of Edo Age in Japan focused on even applying of white powder so that the face would look soft. The eyebrow make-up was a very important part of the make-up. The shapes of eyebrow had been advanced in various styles and there had been eyebrow make-up styles such as "crescent-shaped brow (三日月), "crane style brow (鶴眉) and "Tang style brow (唐眉). The lips had been applied of thick red color, imitating the make-up skill of the ladies in the entertainment business. The lips make-up skill expressing the lips in two colors had been quite popular. Among the make-up skills during the Edo Age in Japan, the "black teeth (齒黑)" can be said as the most unique make-up style of Edo Age.

Selaginella heterostachys Baker (Selaginellaceae): first report for Korea (부처손속 (부처손과)의 미기록종: 각시비늘이끼)

  • Lee, Chang Shook;Kim, Yoo Sung;Lee, Nam Sook
    • Korean Journal of Plant Taxonomy
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    • v.38 no.4
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    • pp.557-563
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    • 2008
  • 일본, 중국, 대만 및 베트남에 분포하는 것으로 알려진 부처손과의 각시비늘이끼 (Selaginella heterostachys Baker)가 강원도 춘천시 남산면 강촌리 저지대에서 발견되었다. 이 종은 선비늘이끼와 유사하나 측면의 소엽이 난상이며 기부가 심장저이고, 중앙부의 소엽은 길며 정단부가 구부러진 점으로 구별된다. 국명은 선비늘이끼보다 중앙부의 소엽이 구부러져 각시의 치마와 비슷하여 각시비늘이끼라고 신칭하였다. 각시비늘이끼의 형태적 특징을 기재하였고, 도해와 생태 사진을 첨부하였다.

Practical Interpretation and Source of Error in Traffic Assignment Based on Korea Transport Database(KTDB) (KTDB 기반 노선배정의 예측오차 원인과 분석결과 해석)

  • KIM, Ikki
    • Journal of Korean Society of Transportation
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    • v.34 no.5
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    • pp.476-488
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    • 2016
  • This study reviewed factors and causes that affect on reliability and accuracy of transportation demand forecasting. In general, the causes of forecasting errors come from variety and irregularity of trip behaviors, data limitation, data aggregation and model simplification. Theoretical understanding about the inevitable errors will be helpful for reasonable decision making for practical transportation policies. The study especially focused on traffic assignment with the KTDB data, and described the factors and causes of errors by classifying six categories such as (1) errors in input data, (2) errors due to spacial aggregation and representation method of network, (3) errors from representing values for variations of traffic patterns, (4) errors from simplification of traffic flow model, and (5) errors from aggregation of route choice behavior.

Evaluation of Network Reshuffling Alternatives Based on Key Factors Affecting the Mode Share of Seoul Metro (서울시 도시철도 이용에 영향을 미치는 요소를 반영한 노선 조정 효과 분석)

  • Jo, Dohyoung;Sohn, Keemin;Kim, Daehyun;Kim, Ikki
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.26 no.6D
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    • pp.935-943
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    • 2006
  • Key factors affecting the mode share of Soul metro are investigated. The log-regression model, which can describe the elasticity of the factors with ease, is established rather than the conventional mode choice model is used. The log-regression model requires lower level of data availability for calibration and identifies the impact of the factors on mode share straightforwardly. As a result, it is found that the main reasons why the current mode share of railway is low are due to several problems such as winding lines, inconvenient transfers and unnecessary bypasses. The calibrated model is adopted to evaluate the network reshuffling alternatives. The network reshuffling is to rearrange the existing inefficient railway lines that have frequent transfers and many winding segments. The proposed network reshuffling, which includes straightening winding lines and changing grade separated transfers into cross-platform transfers, turned out to be a good measure to tackle the problems.

Vascular ring anomaly with a right patent ductus arteriosus and a left aortic arch in a juvenile cat

  • Aki Takeuchi ;Kazumi Shimada ;Lina Hamabe ;Tomohiko Yoshida;Yusuke Ozai ;Miki Hirose ;Aimi Yokoi ;Momoko Watanabe ;Ikki Mitsui ;Ryou Tanaka
    • Journal of Veterinary Science
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    • v.24 no.4
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    • pp.50.1-50.6
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    • 2023
  • This paper reports the clinical findings and surgical treatment of feline right patent ductus arteriosus (RPDA) with a left aortic arch. A two-month-old female Maine Coon was referred for an investigation of regurgitation after weaning. RPDA with a left aortic arch was diagnosed based on the echocardiographic and computed tomography (CT) findings. A right-fourth intercostal thoracotomy was found to be an appropriate approach to the duct. Preoperative diagnosis is crucial and diagnostic imaging, including radiography, echocardiography, and cardiac CT examination, is essential for determining if the aortic arch is right or left.

Gut microbial assessment among Hylobatidae at the National Wildlife Rescue Centre, Peninsular Malaysia

  • Roberta Chaya Tawie Tingga;Millawati Gani;Abd Rahman Mohd-Ridwan;Nor Rahman Aifat;Ikki Matsuda;Badrul Munir Md-Zain
    • Journal of Veterinary Science
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    • v.25 no.5
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    • pp.65.1-65.11
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    • 2024
  • Importance: Recent developments in genetic analytical techniques have enabled the comprehensive analysis of gastrointestinal symbiotic bacteria as a screening tool for animal health conditions, especially the endangered gibbons at the National Wildlife Rescue Centre (NWRC). Objective: High-throughput sequencing based on 16S ribosomal RNA genes was used to determine the baseline gut bacterial composition and identify potential pathogenic bacteria among three endangered gibbons housed in the NWRC. Methods: Feces were collected from 14 individuals (Hylobates lar, n = 9; Hylobates agilis, n = 4; and Symphalangus syndactylus, n = 1) from March to November 2022. Amplicon sequencing were conducted by targeting V3-V4 region. Results: The fecal microbial community of the study gibbons was dominated by Bacteroidetes and Firmicutes (phylum level), Prevotellaceae and Lachnospiraceae/Muribaculaceae (family level), and Prevotella (and its subgroups) (genera level). This trend suggests that the microbial community composition of the study gibbons differed insignificantly from previously reported conspecific or closely related gibbon species. Conclusions and Relevance: This study showed no serious health problems that require immediate attention. However, relatively low alpha diversity and few potential bacteria related to gastrointestinal diseases and streptococcal infections were detected. Information on microbial composition is essential as a guideline to sustain a healthy gut condition of captive gibbons in NWRC, especially before releasing this primate back into the wild or semi-wild environment. Further enhanced husbandry environments in the NWRC are expected through continuous health monitoring and increase diversity of the gut microbiota through diet diversification.