• The Korean Journal of Quaternary Research
• /
• v.15 no.2
• /
• pp.75-81
• /
• 2001

We have analyzed the pollen sequence since the Late Glacial at Sorori Archaeological Site. The Sorori Site is an open site located at Soro-ri, Oksan-myeon, Cheongwon-gun, Chungchongbukdo. The main results are as follows: Four forest zones have been distinguished. \circled1 OS-1 zone : Pinus-Abies-Picea forest (the sub-alpine conifer forest), the Late Glacial (about 15,000~10,000yr. B.P.) ; \circled2 OS-2 zone : Pinus-Colyus forest (the mixed conifer and deciduous broad-leaved forest), R I (about 10,000 yr.B.P.) : \circled3 OS-3 zone : Alnus-Quercus forest (the cool temperate deciduous broadleaved forest), R II(about 10,000~2,000yr.B.P.) : \circled4 OS-4 zone : Pinus forest (the conifer forest), R III (about after 2,000yr.B.P.)

• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.16
• /
• pp.7237-7242
• /
• 2015

Background: Epithelial ovarian cancer (EOC) is the commonest malignancy involving the ovaries. Maximum surgical cytoreduction (MCR) followed by adjuvant taxane-platinum chemotherapy are the standard of care treatments. Aims: To study treatment outcomes of EOC patients that were maximally cyto-reduced and received adjuvant paclitaxel-carboplatin (PC) chemotherapy. Materials and Methods: This retrospective cohort study included 174 patients with EOC treated at the Egyptian National Cancer Institute between 2006 and 2010. For inclusion, they should have had undergone MCR with no-gross residual followed by adjuvant PC chemotherapy. MCR was total abdominal hysterectomy/bilateral salpingo-oophorectomy [TAH/BSO] or unilateral salpingo-oophorectomy [USO] plus comprehensive staging. Results: The median age was 50 years. Most patients were married (97.1%), had offspring (92.5%), were postmenopausal (53.4%), presented with abdominal/pelvic pain and swelling (93.7%), had tumors involving both ovaries (45.4%) without extra-ovarian extension i.e. stage I (55.2%) of serous histology (79.9%) and grade II (87.4%). TAH/BSO was performed in 97.7% of cases. A total of 1,014 PC chemotherapy cycles were administered and were generally tolerable with 93.7% completing 6 cycles. Alopecia and numbness were the commonest adverse events. The median follow up period was 42 months. The 2-year rates for disease free survival (DFS) and overall survival (OS) were 70.7% and 94.8%, respectively. The respective 5-year rates were 52.6% and 81.3%. Advanced stage and high-grade were significantly associated with poor DFS and OS (p<0.001). Age >65 years was associated with poor OS (p =0.008). Using Cox-regression, stage was independent predictor of poor DFS and OS. Age was an independent predictor of poor OS.

• Journal of Microbiology and Biotechnology
• /
• v.26 no.1
• /
• pp.139-144
• /
• 2016

Synthetic oscillators are gene circuits in which the protein expression will change over time. The delay of transcription, translation, and protein folding is used to form this kind of behavior. Here, we tried to design a synthetic oscillator by a negative feedback combined with a positive feedback. With the mutant promoter P_LacC repressed by LacIq and P_Lux activated by AHL-bound LuxR, two gene circuits, Os-LAA and Os-ASV, were constructed and introduced into LacI-deleted E. coli DH5α cells. When glucose was used as the carbon source, a low level of fluorescence was detected in the culture, and the bacteria with Os-ASV showed no oscillation, whereas a small portion of those carrying Os-LAA demonstrated oscillation behavior with a period of about 68.3 ± 20 min. When glycerol was used as the carbon source, bacteria with Os-ASV demonstrated high fluorescence value and oscillation behavior with the period of about 121 ± 21 min.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2014.04a
• /
• pp.325-327
• /
• 2014

애플의 iOS가 처음 출시되고 앱 마켓이 공급자와 소비자 모두에게 각광을 받으며 성공하자 구글에서도 Android를 내세워 구글 마켓을 오픈하였고 결국 다양한 종류, 높은 품질의 애플리케이션들이 사용자들에게 공급되게 되었다. 언제 어디서나 스마트 폰을 통해 고품질의 다양한 앱을 이용할 수 있다는 점이 부각되어 각 마켓의 다운로드 횟수가 급증하는 등 폭발적인 앱 시장을 이룩하게 되었다. 하지만 개발자의 입장에서는 같은 솔루션을 개발할 때 모든 플랫폼을 지원하기 위해 각각의 OS에 맞게 따로 개발하기 때문에 오히려 전체 개발기간이 늦어지는 요소가 되었다. 이런 비효율적인 개발 기간을 단축하기 위해 상용엔진을 구매하여 적용하는 경우가 있지만 영세한 규모의 프로젝트 팀에서 적용하기에는 무리가 있으며 엔진 자체를 배우거나 개발하려는 앱을 위한 커스터마이징하는 기간 역시 짧지 않아 좋은 선택이 될 수 없다. 이에 본 논문에서는 모바일 OS 크로스 플랫폼 지원이 가능한 게임 엔진을 구축하기 위한 방법을 설명하고 이를 활용하여 개발된 프로젝트를 테스트하여 초당 54~61frame 이라는 그래픽 출력 속도를 보임으로써 해당 엔진의 활용 가능성을 증명하였다.

• Korean Journal of Breeding Science
• /
• v.43 no.5
• /
• pp.457-463
• /
• 2011

Plant specific gene family, NAC (NAM, ATAF, and CUC) transcription factors have been characterized for their roles in plant growth, development, and stress tolerance. In this study, we isolated OsNAC69 gene and analyzed expression level by inoculation of bacterial leaf blight pathogen, Xanthomonas oryzae pv. oryzae (Xoo). NAC transcription factor family can be divided into five groups (I-V). On the basis of phylogenetic analysis, OsNAC69 was fall into group II. OsNAC69 was strongly induced 1 hr after infected with Xoo. To investigate its biological function in the rice, we constructed vector for overexpression in rice, and then generated transgenic rice lines. Gene expression of OsNAC69-overexpressed transgenic rice lines were analyzed by northern blot. Analysis of disease resistance to pathogen Xoo, nine OsNAC69-overexpressed transgenic rice lines showing high expression level of OsNAC69 were shown more resistant than wild type. These results suggest that OsNAC69 gene may play regulatory role during pathogen infection.

• TTA Journal
• /
• s.153
• /
• pp.73-78
• /
• 2014

• Asian Pacific Journal of Cancer Prevention
• /
• v.14 no.1
• /
• pp.533-537
• /
• 2013

Background: Malignant melanoma is a cancer that demonstrates rapid progression and atypical clinically features with a poor prognosis. Aim: This study was performed to determine the clinical characteristics and treatment outcomes of patients with malignant melanoma in Turkey. Methods: The medical records of 98 patients between 2007-2012 at our centers were retrieved from the patient registry. Overall survival (OS) was calculated using the Kaplan-Meier method. Results: In our study, with the median follow-up of all patients with cutaneous MM of 46.3 months, the median OS rate of all cases was 43.6 months and 5-year OS was 48.6%. However, five-year OS rates of patients with localized disease (stage I-II) and node involvement (stage III) were 60.3% and 39.6%, respectively. The median OS of stage IV patients was 8.7 months and 1-year OS rate was 26.2%. We showed that advanced stage, male gender, and advanced age in all patients with MM were significant prognostic factors of OS. Conclusions: Compared with the results of current studies from Western countries, we found similar findings concerning demographical features, histological variables and survival analyses for our patients with cutaneous MM in Turkey.

• Asian-Australasian Journal of Animal Sciences
• /
• v.16 no.8
• /
• pp.1137-1142
• /
• 2003

In a balanced incomplete block design, two dry Holstein cows were used to investigate the effect of $\beta$ 1-4 galactooligosaccharides (GOS) supplementation on nitrogen (N) utilization, rumen fermentation and microbial N supply in the rumen. During the experiment, cows were fed four diets: orchardgrass (Dactylis glomerata L.) silage (OS), OS with GOS supplementation (OSG), OS mixed with alfalfa (Medicago sativa L.) silage (MS) and MS with GOS supplementation (MSG). GOS was supplemented at 2% of dry matter intake. Diets were fed at maintenance level of protein and energy. Results showed that N digestion was affected by silage and interaction of silage and GOS supplementation. Cows fed OSG had the highest N digested (p<0.05) followed by MS, OS and MSG. Supplementation of GOS to OS or MS diets tended to improve N utilization through reducing the N losses on dairy cows. There was no effect of GOS supplementation on rumen fermentation parameters (i.e. pH, $NH_3$-N and total VFA) at 1 h and 6 h after feeding. Compared to cows fed MS, cows fed OS silage had higher (p<0.05) allantoin excretion (80.8 vs. 67.1 mmol/d) and higher (p<0.05) total purine derivatives excretion (92.9 vs. 78.5 mmol/d). The microbial N supply in cows fed OSG was higher (p<0.05) than those fed OS, MS and MSG.

• Journal of the Institute of Convergence Signal Processing
• /
• v.10 no.3
• /
• pp.193-197
• /
• 2009

In this paper, we study on design of vehicle control system which is based on ${\mu}C/OS-II$, We component a electric motor drive system for simulator because the most of vehicle part use electric motor for actuator. We use the XC2287 microcontroller which is often used vehicle body controller because XC2287 guarantee high confidence and durability in vehicle industry. The electric motor control system derive PWM from general I/O port in XC2287 microcontroller. The signal is supplied at electric motor after amplifying that using driver circuit. The user control duty of PWM signal through controlling potentiometer which is connected to XC2287. through that, the user control speed of electric motor. we synchronize both input process via controlling potentiometer and PWM output process using semaphore. we verify porting of ${\mu}C/OS-II$ via experimentation.

• Journal of Internet Computing and Services
• /
• v.18 no.1
• /
• pp.105-119
• /
• 2017

Smartphone users hit over eighty-five percentage of Korean populations and personal private items and various information are stored in each user's smartphone. There are so many cases to propagate malicious codes or spywares for the purpose of catching illegally these kinds of information and earning pecuniary gains. Thus, need of information security is outstanding for using smartphone but also user's security perception is important. In this paper, we investigate about how information security affects smartphone operating system choices by users. For statistical analysis, the online survey with questionnaires for users of smartphones is conducted and effective 218 subjects are collected. We test hypotheses via communalities analysis using factor analysis, reliability analysis, independent sample t-test, and linear regression analysis by IBM SPSS statistical package. As a result, it is found that hardware environment influences on perceived ease of use. Brand power affects both perceived usefulness and perceived ease of use and degree of personal risk-accepting influences on perception of smartphone spy-ware risk. In addition, it is found that perceived usefulness, perceived ease of use, degree of personal risk-accepting, and spy-ware risk of smartphone influence significantly on intention to purchase smartphone. However, results of independent sample t-test for each operating system users of Android or iOS do not present statistically significant differences among two OS user groups. In addition, each result of OS user group testing for hypotheses is different from the results of total sample testing. These results can give important suggestions to organizations and managers related to smartphone ecology and contribute to the sphere of information systems (IS) study through a new perspective.