• JSTS:Journal of Semiconductor Technology and Science
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• v.14 no.1
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• pp.8-22
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• 2014

In the past few decades, CMOS logic technologies and devices have been successfully developed with the steady miniaturization of the feature size. At the sub-30-nm CMOS technology nodes, one of the main hurdles for continuously and successfully scaling down CMOS devices is the parametric failure caused by random variations such as line edge roughness (LER), random dopant fluctuation (RDF), and work-function variation (WFV). The characteristics of each random variation source and its effect on advanced device structures such as multigate and ultra-thin-body devices (vs. conventional planar bulk MOSFET) are discussed in detail. Further, suggested are suppression methods for the LER-, RDF-, and WFV-induced threshold voltage (VTH) variations in advanced CMOS logic technologies including the double-patterning and double-etching (2P2E) technique and in advanced device structures including the fully depleted silicon-on-insulator (FD-SOI) MOSFET and FinFET/tri-gate MOSFET at the sub-30-nm nodes. The segmented-channel MOSFET (SegFET) and junctionless transistor (JLT) that can suppress the random variations and the SegFET-/JLT-based static random access memory (SRAM) cell that enhance the read and write margins at a time, though generally with a trade-off between the read and the write margins, are introduced.

• Journal of Information Technology Services
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• v.15 no.4
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• pp.25-39
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• 2016

The drone is an unmanned aerial vehicle which has no human pilot. Drones can be classified into military drones, commercial drones, and personal drones by usage. Also, drones can be classified from large-sized to nano-sized drone by size and autonomous, remote controlled drone by control type. Especially, military drones can be classified into low-altitude drones, medium-altitude, and high-altitude drones by altitude. Recently, the drone industry is one of the fast growing industries in the world. As drone technologies have become more advanced and cost-effective, Korean government has set its goal to become a top-level country in drone business. However, the government's strict regulation for drone operations is one of the biggest hurdles for the development of the related technologies in Korea and other countries. For example, critical problems for drone delivery can be classified into technical issues and institutional issues. Technical issues include durability, conditional awareness, grasp and release mechanisms, collision avoidance systems, drone operating system. Institutional issues include pilot and operator licensing, privacy rules, noise guidelines, security rules, education for drone police. This study analyzes the trends of the drone industry from the viewpoint of technology and regulation. Also, we define the business areas of drone utilization. Especially, the drone business types or models for public sector are proposed. Drone services or functions promoting public interests need to be aligned with the business reference model of Korean government. To define ten types of drone uses for public sector, we combine the business types of government with the future uses of drones that are proposed by futurists and business analysts. Future uses of drones can be divided into three sectors or services. First, drone services for public or military sectors include early warning systems, emergency services, news reporting, police drones, library drones, healthcare drones, travel drones. Second, drone services for commercial or industrial services include parcel delivery drones, gaming drones, sporting drones, farming and agriculture drones, ranching drones, robotic arm drones. Third, drone services for household sector include smart home drones.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.11 no.1
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• pp.66-74
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• 2007

The most commonly used navigation systems work on Windows CE platforms. Linux-based embedded terminals have price competitiveness, because Linux is a free operation system. In order to develop map services on Linux-based embedded terminals, there were a number of technical hurdles that had to be resolved. Since the Linux-based embedded terminals is a low power, low cost, and small size platform with low processing capabilities, we must have developed the spatial database engine that minimize the number of disk accesses. We solved problems that are the processing korean language and the lack of debugging tools on Linux. In this paper, we has developed the spatial database engine and user interfaces on hand-held terminals based on embedded Linux for implementing the location based map system With view of this implementation results, we confirmed the possibility of using our embedded linux terminal as telematics terminals or navigation terminals.

• Asian-Australasian Journal of Animal Sciences
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• v.32 no.8_spc
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• pp.1266-1274
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• 2019

This paper presents a review of dairy goat production in sub-Saharan Africa (SSA) from 2010- 2017, its current state, constraints and prospects for research and development. Since the introduction of dairy goats in SSA in pre-colonial times, their populations have continued to increase due to declining land size as a result of land fragmentation and increasing demand for goat milk. The current goat population in SSA is 372,716,040 head of which only 15.98% used for milk production. Populations in the Eastern and Western regions of SSA have shown an increasing trend from 2010 to 2017. The Southern Africa goat population is on the decline at an annual rate of about 1.77% whereas Central Africa has had a constant goat population within the same period. Eastern Africa reported the highest increase in the population of goats used for milk production. Milk production was highest in Eastern Africa and lowest in Southern Africa. However, dairy goat productivity remained constant in the Eastern region throughout the review period. Dairy goats are mainly raised under smallholder mixed crop-livestock systems. To enhance the development of the dairy goat, concerted efforts should be made to alleviate the constraints that stifle its growth. These constraints can be categorized into nutrition and feeding, breeding and reproduction, diseases, parasites, climate change, and underdeveloped dairy goat products market. Effective management of dairy goats requires a holistic approach and there is the need to expand the markets by further sensitization on the nutritional and medicinal advantages of dairy goat products. In order to achieve rapid development in the dairy goat sub sector, research and development initiatives should be directed towards alleviating the hurdles in nutrition and feeding, breeding, animal health and resilience as well as dairy goat markets.

• Food Science and Industry
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• v.49 no.4
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• pp.3-18
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• 2016

The status of Korean food security was analyzed by considering world food situation and food self-sufficiency of Korea, and the hurdles to be solved by science and technology were highlighted. The role of food science and technology in preparing for future food crisis was reviewed in four categories: application of modern biotechnology to increase food production, use of irradiation technology for food storage, food processing technology for rice utilization in particular, and improving food safety regulation system for waste reduction.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.49 no.7
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• pp.593-599
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• 2021

The demand for e-VTOL aircraft is expected to be increased rapidly in the future as a means of urban transportation due to operating cost reduction, eco-friendliness and convenience of vertical take-off and landing using pilot-aids automation system. However, there are many technical hurdles to be solved in securing safety and certification which are essential for commercialization and urban operation. So far, there is no e-VTOL aircraft that has received type certificate and standard airworthiness certificate due to the technical problems and safety requirement differences with conventional aircraft. The e-VTOL aircraft certification should also meet the equivalent level of safety required by the current airworthiness standards, but there are existing problems in securing safety and meeting current standards. In this study, the e-VTOL's certification problems and technical limitations in satisfying the current standards are presented.

• The Plant Pathology Journal
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• v.37 no.6
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• pp.555-565
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• 2021

Bacteriophages infecting Acidovorax citrulli, the causal agent of bacterial fruit blotch, have been proven to be effective for the prevention and control of this disease. However, the occurrence of bacteriophage-resistant bacteria is one of hurdles in phage biocontrol and the understanding of phage resistance in this bacterium is an essential step. In this study, we aim to investigate possible phage resistance of A. citrulli and relationship between phage resistance and pathogenicity, and to isolate and characterize the genes involved in these phenomena. A phage-resistant and less-virulent mutant named as AC-17-G1 was isolated among 3,264 A. citrulli Tn5 mutants through serial spot assays and plaque assays followed by pathogenicity test using seed coating method. The mutant has the integrated Tn5 in the middle of a cupin protein gene. This mutant recovered its pathogenicity and phage sensitivity by complementation with corresponding wild-type gene. Site-directed mutation of this gene from wild-type by CRISPR/Cas9 system resulted in the loss of pathogenicity and acquisition of phage resistance. The growth of AC-17-G1 in King's B medium was much less than the wild-type, but the growth turned into normal in the medium supplemented with D-mannose 6-phosphate or D-fructose 6-phosphate indicating the cupin protein functions as a phosphomannos isomerase. Sodium dodecyl sulfa analysis of lipopolysaccharide (LPS) extracted from the mutant was smaller than that from wild-type. All these data suggest that the cupin protein is a phosphomannos isomerase involved in LPS synthesis, and LPS is an important determinant of pathogenicity and phage susceptibility of A. citrulli.

• Journal of the Korea Institute of Building Construction
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• v.23 no.3
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• pp.315-326
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• 2023

The design principles and implementation of rebar lap splice in architectural structures are governed by building regulations. Nevertheless, the minimization of rebar-cutting waste (RCW) is often impeded by the mandatory requirements pertaining to the rebar lapping zone as prescribed in design codes. In real-world construction scenarios, compliance with these rules often falls short due to hurdles concerning productivity, quality, safety, time, and cost. This discrepancy between code stipulations and on-the-ground construction practices necessitates an academic exploration. The goal of this research was to delve into the effect of rebar lap splice placement on the robustness and constructability of building edifices. The study initially took on a review of the computation of rebar lapping length and the rules revolving around the lapping zone. Following this, a structural robustness and constructability examination was undertaken, focusing on adherence to the lap splice zone. The interpretations and deductions of the research led to the following insights: (1) the efficacy of rebar lap splice is not solely contingent on the moment, and (2) the implementation of rebar lap splice beyond the specified zone can match the structural integrity and robustness of those confined within the designated area. As a result, the constraints on the rebar lapping zone ought to be revisited and possibly relaxed. The conclusions drawn from this research are anticipated to reconcile the disconnect between building codes and practical construction conditions, furnishing invaluable academic substantiation to further the endeavor of achieving near-zero RCW.

• International Journal of Computer Science & Network Security
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• v.23 no.10
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• pp.135-146
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• 2023

An effective educational program warrants the inclusion of an innovative construction which enhances the higher education efficacy in such a way that accelerates the achievement of desired results and reduces the risk of failures. Educational Decision Support System (EDSS) has currently been a hot topic in educational systems, facilitating the pupil result monitoring and evaluation to be performed during their development. Insufficient information systems encounter trouble and hurdles in making the sufficient advantage from EDSS owing to the deficit of accuracy, incorrect analysis study of the characteristic, and inadequate database. DMTs (Data Mining Techniques) provide helpful tools in finding the models or forms of data and are extremely useful in the decision-making process. Several researchers have participated in the research involving distributed data mining with multi-agent technology. The rapid growth of network technology and IT use has led to the widespread use of distributed databases. This article explains the available data mining technology and the distributed data mining system framework. Distributed Data Mining approach is utilized for this work so that a classifier capable of predicting the success of students in the economic domain can be constructed. This research also discusses the Intelligent Knowledge Base Distributed Data Mining framework to assess the performance of the students through a mid-term exam and final-term exam employing Multi-agent system-based educational mining techniques. Using single and ensemble-based classifiers, this study intends to investigate the factors that influence student performance in higher education and construct a classification model that can predict academic achievement. We also discussed the importance of multi-agent systems and comparative machine learning approaches in EDSS development.

• Molecules and Cells
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• v.46 no.10
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• pp.579-588
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• 2023

Sarcomas are rare and heterogeneous mesenchymal neoplasms originating from the bone or soft tissues, which pose significant treatment challenges. The current standard treatment for sarcomas consists of surgical resection, often combined with chemo- and radiotherapy; however, local recurrence and metastasis remain significant concerns. Although immunotherapy has demonstrated promise in improving long-term survival rates for certain cancers, sarcomas are generally considered to be relatively less immunogenic than other tumors, presenting substantial challenges for effective immunotherapy. In this review, we examine the possible opportunities for sarcoma immunotherapy, noting cancer testis antigens expressed in sarcomas. We then cover the current status of immunotherapies in sarcomas, including progress in cancer vaccines, immune checkpoint inhibitors, and adoptive cellular therapy and their potential in combating these tumors. Furthermore, we discuss the limitations of immunotherapies in sarcomas, including a low tumor mutation burden and immunosuppressive tumor microenvironment, and explore potential strategies to tackle the immunosuppressive barriers in therapeutic interventions, shedding light on the development of effective and personalized treatments for sarcomas. Overall, this review provides a comprehensive overview of the current status and potential of immunotherapies in sarcoma treatment, highlighting the challenges and opportunities for developing effective therapies to improve the outcomes of patients with these rare malignancies.