• 제목/요약/키워드: host factors

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이용자, 정보원천 및 플랫폼 차원에서의 라이브 커머스 이용 만족도 영향 요인 고찰 (An Analysis of Determinants Affecting Satisfaction of Usage of Live Commerce from the Perspective of User, Information Source and Platform)

  • 이성준
    • 한국콘텐츠학회논문지
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    • 제21권3호
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    • pp.576-589
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    • 2021
  • 언택트 소비 문화가 점차 확산하는 추세 속에서 실시간 방송과 전자상거래가 결합된 형태인 라이브 커머스가 많은 이들로부터 주목받고 있다. 이런 가운데 본 연구는 어떤 요인들이 라이브 커머스 이용 만족을 이끌어 내는지 살펴보고자 하였다. 특히 기존 연구를 바탕으로 이용자, 정보원천 및 플랫폼 차원에서 라이브 커머스 만족도 영향 가능 요인들을 도출하여 이들 요인들과 라이브 커머스 이용 만족간의 관계를 실증적으로 살펴보았다. 자료는 20대 및 30대 라이브 커머스 이용 경험자 218명을 대상으로 한 온라인 서베이 방식으로 수집되었으며 수집된 자료의 분석을 위해선 위계적 회귀 분석 방법을 사용하였다. 연구결과, 이용자 차원에서는 우울증 및 혁신성, 정보원천 차원에서는 쇼호스트의 매력성, 그리고 플랫폼 차원에서는 물리적 어포던스와 인지된 이용자간 상호작용성이 라이브 커머스 만족도에 유의미한 영향을 미치는 것으로 나타났다.

Whole-Genome Characterization of Alfalfa Mosaic Virus Obtained from Metagenomic Analysis of Vinca minor and Wisteria sinensis in Iran: with Implications for the Genetic Structure of the Virus

  • Moradi, Zohreh;Mehrvar, Mohsen
    • The Plant Pathology Journal
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    • 제37권6호
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    • pp.619-631
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    • 2021
  • Alfalfa mosaic virus (AMV), an economically important pathogen, is present worldwide with a very wide host range. This work reports for the first time the infection of Vinca minor and Wisteria sinensis with AMV using RNA sequencing and reverse transcription polymerase chain reaction confirmation. De novo assembly and annotating of contigs revealed that RNA1, RNA2, and RNA3 genomic fragments consist of 3,690, 2,636, and 2,057 nucleotides (nt) for IR-VM and 3,690, 2,594, and 2,057 nt for IR-WS. RNA1 and RNA3 segments of IR-VM and IR-WS closely resembled those of the Chinese isolate HZ, with 99.23-99.26% and 98.04-98.09% nt identity, respectively. Their RNA2 resembled that of Canadian isolate CaM and American isolate OH-2-2017, with 97.96-98.07% nt identity. The P2 gene revealed more nucleotide diversity compared with other genes. Genes in the AMV genome were under dominant negative selection during evolution, and the P1 and coat protein (CP) proteins were subject to the strongest and weakest purifying selection, respectively. In the population genetic analysis based on the CP gene sequences, all 107 AMV isolates fell into two main clades (A, B) and isolates of clade A were further divided into three groups with significant subpopulation differentiation. The results indicated moderate genetic variation within and no clear geographic or genetic structure between the studied populations, implying moderate gene flow can play an important role in differentiation and distribution of genetic diversity among populations. Several factors have shaped the genetic structure and diversity of AMV: selection, recombination/reassortment, gene flow, and random processes such as founder effects.

Importance of Political Elements to Attract FDI for ASEAN and Korean Economy

  • Teeramungcalanon, Monthinee;Chiu, Eric M.P.;Kim, Yoonmin
    • Journal of Korea Trade
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    • 제24권8호
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    • pp.63-80
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    • 2020
  • Purpose - Recent empirical studies have shown that FDI is expected to be strongly associated with democratic governance, political stability, and sound macroeconomic conditions of the host country. We attempt to take it a step further to see if governments implement a major change in institutional characteristics, will the institutional reform toward better governance have a substantive effect in enhancing FDI inflows. This paper thus aims to analyze the importance of good governance as an important factor in the attractiveness of FDI inflows in ASEAN+3 (Korea, China, Japan) countries. Design/methodology - To determine the effects of good governance on FDI inflows across ASEAN+3 countries recorded between 1996-2018, the Worldwide Governance Indicators (WGI) are used to investigate the impact of good governance on FDI inflows. The model has been estimated by using fixed effects to show the robustness of the results. Findings - Our main findings can be summarized as follows: Political Stability, Rule of Law, and Voice and Accountability have a statistically significant impact on the inflow of FDI in the ASEAN+3 Countries, especially for Korean economy. Moreover, GDP growth continue to exert their positive influence. However, Regulatory Quality, Government Effectiveness and Control of Corruption, though equally important, are insignificant to attract FDI inflows. The key finding is that good governance has a significant impact on inward FDI in the ASEAN+3 countries. Originality/value - Existing studies focus on the impact of political factors on FDI across countries. This paper instead attempts to investigate which type of good governance is the most important in promoting FDI inflows across ASEAN+3 countries, which is essential for multinationals to consider when choosing a foreign site as a possible FDI destination.

The impact of different diets and genders on fecal microbiota in Hanwoo cattle

  • Seunghyeun, Sim;Huseong, Lee;Sang, Yoon;Hyeonsu, Seon;Cheolju, Park;Minseok, Kim
    • Journal of Animal Science and Technology
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    • 제64권5호
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    • pp.897-910
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    • 2022
  • Bovine fecal microbiota is important for host health and its composition can be affected by various factors, such as diet, age, species, breed, regions, and environments. The objective of this study was to evaluate the impact of diet and gender on fecal microbiota in Korean native Hanwoo cattle. The 16S rRNA gene amplicon sequencing of fecal microbiota was conducted from 44 Hanwoo cattle divided into four groups: (1) 11 heifers fed an oat hay plus total mixed ration (TMR) diet for breeding (HOTB), (2) 11 heifers fed an early fattening TMR diet (HEFT), (3) 11 steers fed the early fattening TMR diet (SEFT), and (4) 11 steers fed the late fattening TMR diet (SLFT). Firmicutes and Bacteroidota were the first and second most dominant phyla in all the samples, respectively. The Firmicutes/Bacteroidota (F/B) ratio associated with feed efficiency was significantly greater in the SLFT group than in the other groups. At the genus level, Romboutsia, Paeniclostridium, and Turicibacter were the most abundant in the SLFT while Akkermansia, Bacteroides, and Monoglobus were the most abundant in the HOTB group. Although the same early fattening TMR diet was fed to Hanwoo heifers and steers, Marvinbryantia and Coprococcus were the most abundant in the HEFT group while Alistipes and Ruminococcus were the most abundant in the SEFT group. Shannon and Simpson diversity indices were significantly lower in the SLFT group than in the other groups. Distribution of fecal microbiota and functional genetic profiles were significantly different among the four treatment groups. The present study demonstrates that different diets and genders can affect fecal microbiota and the F/B ratio may be associated with feed efficiency in Hanwoo cattle. Our results may help develop strategies to improve gut health and productivity through manipulation of fecal microbiota using the appropriate diet considering Hanwoo cattle gender.

소아 신장이식 환자에서 발생한 파르보바이러스 B19에 의한 심한 빈혈에 대한 증례 보고 및 문헌 고찰 (Severe Anemia Caused by Parvovirus B19 Infection in Two Pediatric Kidney Transplantation Recipients)

  • 김경란;박환희;김두리;조희연;이상훈;이석구;김예진
    • Pediatric Infection and Vaccine
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    • 제28권3호
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    • pp.181-188
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    • 2021
  • 신장이식 환자에서 만성 빈혈은 치료 과정 중 발생하는 합병증으로 바이러스 감염, 적혈구형성호르몬결핍, 출혈, 면역억제제의 부작용 등과 관련이 있다. 신장이식 환자에서 파르보바이러스 B19에 의한 빈혈은 초감염 혹은 기존 감염의 재활성화로 발생할 수 있으며, 아직 이에 대한 치료법은 정립이 되어 있지 않다. 특히, 소아청소년 신장이식 환자에 대한 보고나 자료는 더욱 드물다. 저자들은 소아청소년 신장이식 환자에서 발생한 심각한 빈혈을 파르보바이러스 B19 PCR 검사법으로 진단하고, 정맥내글로불린으로 재발 없이 성공적으로 치료한 두 증례와 문헌 고찰을 보고하는 바이다.

What Promotes International Sustainable Development of Green Ventures? The Joint Effects of Entrepreneurial Orientation and Home Country-Based Networks

  • Dejin Su;Yeong-Gil Kim
    • Journal of Korea Trade
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    • 제26권4호
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    • pp.39-62
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    • 2022
  • Purpose - Along with the growing awareness of environmental sustainability, international green entrepreneurship is expected to realize international sustainable development (ISD) by introducing ecological innovation results, using fewer resources consumption, and reducing negative environmental impacts. Building upon contingency theory and social network theory, this paper attempts to explore the role of home country-based networks (technology ties and business ties) as contingent factors that might impact the effectiveness of entrepreneurial orientation (EO) in promoting ISD among green ventures. Design/methodology - Original data were collected from 127 green ventures in China based on the random sampling technique. These green ventures mainly focus on the lower use of energy or materials, lower CO2 emissions, and higher ecological benefits located in the Fujian province, which highlights green economic growth and economic cooperation with international markets. Moderated hierarchical linear regression analysis was conducted to test our hypotheses concerning the main relationship between EO (innovativeness, proactiveness, and risk-taking) and ISD as well as the moderating effects of home country-based networks (technology ties and business ties) on the main relationship. Findings - Empirical results indicate that: first, both innovativeness and proactiveness positively affect ISD; second, both technology ties and business ties at home might significantly strengthen the positive relationship between innovativeness (or proactiveness) and ISD. However, this study did not find significant moderating effects of technology ties or business ties at home on the relationship between risk-taking and ISD. Originality/value - Since previous literature often gives more focus on the host country context of social networks, this study shifts to a home country-based network context. Therefore, our research might enrich the international green entrepreneurship literature by empirically investigating the contingent value of home country-based networks in the relationship between EO and ISD in the context of an emerging economy such as China.

Expression of cytokines and co-stimulatory molecules in the Toxoplasma gondii-infected dendritic cells of C57BL/6 and BALB/c mice

  • Jae-Hyung Lee;Jae-Min Yuk;Guang-Ho Cha;Young-Ha Lee
    • Parasites, Hosts and Diseases
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    • 제61권2호
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    • pp.138-146
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    • 2023
  • Toxoplasma gondii is an intracellular protozoan parasite which can infect most warm-blooded animals and humans. Among the different mouse models, C57BL/6 mice are more susceptible to T. gondii infection compared to BALB/c mice, and this increased susceptibility has been attributed to various factors, including T-cell responses. Dendritic cells (DCs) are the most prominent type of antigen-presenting cells and regulate the host immune response, including the response of T-cells. However, differences in the DC responses of these mouse strains to T. gondii infection have yet to be characterized. In this study, we cultured bone marrow-derived DCs (BMDCs) from BALB/c and C57BL/6 mice. These cells were infected with T. gondii. The activation of the BMDCs was assessed based on the expression of cell surface markers and cytokines. In the BMDCs of both mouse strains, we detected significant increases in the expression of cell surface T-cell co-stimulatory molecules (major histocompatibility complex (MHC) II, CD40, CD80, and CD86) and cytokines (tumor necrosis factor (TNF)-α, interferon (IFN)-γ, interleukin (IL)-12p40, IL-1β, and IL-10) from 3 h post-T. gondii infection. The expression of MHC II, CD40, CD80, CD86, IFN-γ, IL-12p40, and IL-1β was significantly higher in the T. gondii-infected BMDCs obtained from the C57BL/6 mice than in those from the BALB/c mice. These findings indicate that differences in the activation status of the BMDCs in the BALB/c and C57BL/6 mice may account for their differential susceptibility to T. gondii.

해외진출 기업 유형의 결정요인 분석: 부패와 정치적 위험 영향을 중심으로 (Analysis of Determinants on the Entry Modes of Multinational Firms: Focused on the Effects of Corruption and Political Instability)

  • 조정환;김태황
    • 무역학회지
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    • 제43권1호
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    • pp.177-197
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    • 2018
  • 본 연구는 투자 대상국의 외부 불확실성이 다국적 기업의 해외진출 유형에 미치는 영향을 실증 분석하였다. 외부 불확실성 요인으로는 투자 대상국의 부패 정도와 정치적 위험 지수를 이용하였고, 해외진출 유형으로는 인수합병(M&A)과 그린필드 FDI(Greenfield foreign direct investment)를 고려하였다. 본 연구의 관심변수인 부패와 정치적 위험과 관련해서는 부패 수준이 낮고 정치적으로 안정될수록 M&A 투자가 증가하는 것으로 나타났다. 그러나 그린필드 FDI와 관련해서는 정치적 안정 변수만이 통계적으로 유의미한 양(+)의 값을 갖는 것으로 분석되었다. 이에 따라, M&A 유형은 부패와 정치적 위험 수준 모두에 민감하게 반응하지만, 그린필드 FDI는 투자 결과에 따라 사후적으로 매몰비용의 성격을 포함하므로 부패 수준보다는 투자 대상국의 정치적 안정성을 의미있고 강력하게 고려하는 것으로 추론된다.

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한국 패션기업의 해외시장 진입방식 연구: 해외직접투자 유형의 결정요인 분석을 중심으로 (Korean Fashion Firms' Entry into Foreign Markets: Empirical Analysis of Determinants of their Choice of Foreign Direct Investment Modes)

  • 김혜영;나원찬
    • 무역학회지
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    • 제42권1호
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    • pp.189-215
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    • 2017
  • 최근 우리나라의 패션기업들의 국제화가 매우 활발한데도 불구하고 기업들의 주요한 해외진출 방식인 해외직접투자에 관한 국내 연구는 거의 이루어지지 않았다. 본 연구는 최근 해외직접 투자로 해외에 진출한 한국 패션기업들을 대상으로 그 투자방식의 선택을 결정하는 요인들을 분석한 것이다. 이를 위해 먼저 패션산업의 특성을 분석하고 패션기업들의 국제화와 해외진출에 관한 최근의 국내 연구를 고찰하였다. 이어 단독투자, 합작투자, M&A 등 3가지 대표적인 해외직접투자 방식 간 선택에 영향을 미치는 요인으로 모기업의 규모, 국제사업 경험, 국제전략 등 기업 내부 요인과 시장잠재력, 문화적 거리, 해외투자 위험 등 기업 외부 요인들을 선정하여 이들과 투자방식 간 선택에 관한 연구가설을 설정하였다. 가설 검증을 위해 해외시장에 진출한 100개 한국 패션기업들에 관한 2차 자료를 수집하여 다항 로지스틱 회귀분석을 실시하였고, 그 결과 문화적 거리변수를 제외한 5개의 요인들이 유의하게 영향을 미침을 밝혔다. 이 논문은 학문적으로 패션산업의 국제화에 관한 연구의 발전 및 실무적으로 기업의 해외진출 전략 수립에 긍정적으로 기여할 수 있을 것으로 기대한다.

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COVID-19 progression towards ARDS: a genome wide study reveals host factors underlying critical COVID-19

  • Shama Mujawar;Gayatri Patil;Srushti Suthar;Tanuja Shendkar;Vaishnavi Gangadhar
    • Genomics & Informatics
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    • 제21권2호
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    • pp.16.1-16.14
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    • 2023
  • Coronavirus disease 2019 (COVID-19) is a viral infection produced by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus epidemic, which was declared a global pandemic in March 2020. The World Health Organization has recorded around 43.3 billion cases and 59.4 million casualties to date, posing a severe threat to global health. Severe COVID-19 indicates viral pneumonia caused by the SARS-CoV-2 infections, which can induce fatal consequences, including acute respiratory distress syndrome (ARDS). The purpose of this research is to better understand the COVID-19 and ARDS pathways, as well as to find targeted single nucleotide polymorphism. To accomplish this, we retrieved over 100 patients' samples from the Sequence Read Archive, National Center for Biotechnology Information. These sequences were processed through the Galaxy server next generation sequencing pipeline for variant analysis and then visualized in the Integrative Genomics Viewer, and performed statistical analysis using t-tests and Bonferroni correction, where six major genes were identified as DNAH7, CLUAP1, PPA2, PAPSS1, TLR4, and IFITM3. Furthermore, a complete understanding of the genomes of COVID-19-related ARDS will aid in the early identification and treatment of target proteins. Finally, the discovery of novel therapeutics based on discovered proteins can assist to slow the progression of ARDS and lower fatality rates.