• Title/Summary/Keyword: high-throughput system

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Fin Cutting Line Detection Technique based on RANSAC for Fish Cutting Automation System (생선 가공 자동화 시스템을 위한 RANSAC 기반 지느러미 절단선 검출 기법)

  • Jang, Yonghun;Park, Changhyeon
    • Journal of KIISE
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    • v.43 no.3
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    • pp.346-352
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    • 2016
  • The fishing industry requires many workers to manually carry out the jobs of sorting and cutting fishes. There are therefore many dangerous situations in their working environment and the throughput is inefficiently low. This paper introduces an automatic fin cutting system based on RANSAC that is able to increase the throughput of fish processing jobs. The system proposed in this paper first detects the edges of a fish using a high-pass filter. The boundary lines between fin and body are then detected by adjusting parameters and the threshold of the noise filters. Finally, the optimal cutting lines are detected using RANSAC. Through an experiment with a sample of 50 fishes, this paper shows that the proposed system detects the cutting lines with about 90% accuracy.

TCP Buffer Tuning based on MBT for High-Speed Transmissions in Wireless LAN (무선 랜 고속전송을 위한 최대버퍼한계 기반 TCP 버퍼튜닝)

  • Mun, Sung-Gon;Lee, Hong-Seok;Choo, Hyun-Seung;Kong, Won-Young
    • Journal of Internet Computing and Services
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    • v.8 no.1
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    • pp.15-23
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    • 2007
  • Wireless LAN (IEEE 802.11) uses traditional TCP for reliable data transmission, But it brings the unintentional packet loss which is not congestion loss caused by handoff, interference, and fading in wireless LAN. In wireless LAN, TCP experiences performance degradation because it consumes that the cause of packet loss is congestion, and it decrease the sending rate by activating congestion control algorithm. This paper analyzes that correlation of throughput and buffer size for wireless buffer tuning. We find MBT (Maximum Buffer Threshold) which does not increase the throughput through the analysis, For calculation of MBT, we experiment the throughput by using high volume music data which is creased by real-time performance of piano. The experiment results is shown that buffer tuing based on MBT shows 20.3%, 21.4%, and 45.4% throughput improvement under 5ms RTT, 10ms RTT, and 20ms RTT, respectively, comparing with the throughput of operation system default buffer size, In addition, we describe that The setting of TCP buffer size by exceeding MBT does not have an effect on the performance of TCP.

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Full validation of high-throughput bioanalytical method for the new drug in plasma by LC-MS/MS and its applicability to toxicokinetic analysis

  • Han, Sang-Beom
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2006.11a
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    • pp.65-74
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    • 2006
  • Modem drug discovery requires rapid pharmacokinetic evaluation of chemically diverse compounds for early candidate selection. This demands the development of analytical methods that offer high-throughput of samples. Naturally, liquid chromatography / tandem mass spectrometry (LC-MS/MS) is choice of the analytical method because of its superior sensitivity and selectivity. As a result of the short analysis time(typically 3-5min) by LC-MS/MS, sample preparation has become the rate- determining step in the whole analytical cycle. Consequently tremendous efforts are being made to speed up and automate this step. In a typical automated 96-well SPE(solid-phase extraction) procedure, plasma samples are transferred to the 96-well SPE plate, internal standard and aqueous buffer solutions are added and then vacuum is applied using the robotic liquid handling system. It takes only 20-90 min to process 96 samples by automated SPE and the analyst is physically occupied for only approximately 10 min. Recently, the ultra-high flow rate liquid chromatography (turbulent-flow chromatography)has sparked a huge interest for rapid and direct quantitation of drugs in plasma. There is no sample preparation except for sample aliquotting, internal standard addition and centrifugation. This type of analysis is achieved by using a small diameter column with a large particle size(30-5O ${\mu}$m) and a high flow rate, typically between 3-5 ml/min. Silica-based monolithic HPLC columns contain a novel chromatographic support in which the traditional particulate packing has been replaced with a single, continuous network (monolith) of pcrous silica. The main advantage of such a network is decreased backpressure due to macropores (2 ${\mu}$m) throughout the network. This allows high flow rates, and hence fast analyses that are unattainable with traditional particulate columns. The reduction of particle diameter in HPLC results in increased column efficiency. use of small particles (<2 urn), however, requires p.essu.es beyond the traditional 6,000 psi of conventional pumping devices. Instrumental development in recent years has resulted in pumping devices capable of handling the requirements of columns packed with small particles. The staggered parallel HPLC system consists of four fully independent binary HPLC pumps, a modified auto sampler, and a series of switching and selector valves all controlled by a single computer program. The system improves sample throughput without sacrificing chromatographic separation or data quality. Sample throughput can be increased nearly four-fold without requiring significant changes in current analytical procedures. The process of Bioanalytical Method Validation is required by the FDA to assess and verify the performance of a chronlatographic method prior to its application in sample analysis. The validation should address the selectivity, linearity, accuracy, precision and stability of the method. This presentation will provide all overview of the work required to accomplish a full validation and show how a chromatographic method is suitable for toxirokinetic sample analysis. A liquid chromatography/tandem mass spectrometry (LC-MS/MS) method developed to quantitate drug levels in dog plasma will be used as an example of tile process.

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Fluorescence-based Assay System for Endocannabinoid Degradation Enzyme, Fatty Acid Amide Hydrolase

  • Kim, Dae-Woong;Kim, Gun-Joong;Kim, Hae-Jo;Ghil, Sung-Ho
    • Biomedical Science Letters
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    • v.16 no.4
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    • pp.279-285
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    • 2010
  • Endogenous cannabinoids (endocannabinoids) display various pharmacological effects including pain control, anti-inflammation, and neuroprotection. The synthesis and release of endocannabinoids are regulated under both physiological and pathological conditions. The main degrading enzyme of endocannabinoid is fatty acid amide hydrolase (FAAH). Therefore we have developed the fluorescence-based assay system for FAAH. We established stable CosM6 cell lines expressing human FAAH. We also synthesized 2-oxo-2H-chromen-7-yl decanoate (DAEC) as a fluorogenic substrate for FAAH. When crude membrane extracts stably expressing FAAH was incubated with DAEC at $25^{\circ}C$, FAAH reacted specifically to DAEC and catalyzes the hydrolysis of DAEC into decanoic acid and highly fluorescent coumarin. Furthermore, the serin hydrolase inhibitor, phenylmethanesulfonylfluoride, inhibited the coumarin release to the reaction buffer in concentration dependent manner. This assay system is suitable for high-throughput screening since this system has simple experimental procedure and measurement method.

Numerical Analysis for Improvement of Cooling Performance in Nanoimprint Lithography Process (나노임프린트 공정에서의 냉각성능 개선에 대한 수치해석)

  • Lee, Ki-Yeon;Jun, Sang-Bum;Kim, Kug-Weon
    • Journal of the Semiconductor & Display Technology
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    • v.10 no.4
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    • pp.89-94
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    • 2011
  • In recent years there have been considerable attentions on nanoimprint lithography (NIL) by the display device and semiconductor industry due to its potential abilities that enable cost-effective and high-throughput nanofabrication. A major disadvantage of thermal NIL is the thermal cycle, that is, heating over glass transition temperature and then cooling below it, which requires a significant amount of processing time and limits the throughput. One of the methods to overcome this disadvantage is to improve the cooling performance in NIL process. In this paper, a numerical analysis model of cooling system in thermal NIL was development by CAD/CAE program and the performance of the cooling system was analyzed by the model. The calculated temperatures of nanoimprint device were verified by the measurements. By using the analysis model, the case that the cooling material is replaced by liquid nitrogen is investigated.

A New Vehicle Dispatching in Semiconductor Intra-Bay Material Handling System (반도체 Intra-Bay 물류시스템에서의 차량 배차)

  • Koo, Pyung-Hoi;Suh, Jung-Dae;Jang, Jae-Jin
    • IE interfaces
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    • v.16 no.spc
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    • pp.93-98
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    • 2003
  • This paper addresses an AGV dispatching problem in semiconductor clean-room bays where AGVs move cassettes of wafers between machines or machines and a central buffer. Since each machine in a bay has a local buffer of limited capacity, material flow should be controlled in a careful way to maintain high system performance. It is regarded that two most important performance measures in a semiconductor bay are throughput rate and lead-time. The throughput rate is determined by a bottleneck resource and the lead-time depends on smooth material flow in the system. This paper presents an AGV dispatching procedure based on the concept of theory of constraints (TOC), by which dispatching decisions are made to utilize the bottleneck resource at the maximum level and to smooth the flow of material. The new dispatching procedure is compared with existing dispatching rules through simulation experiments.

Development of High Throughput Screening Techniques Using Food-borne Library against Anti-asthma Agents (식품소재 라이브러리를 이용한 천식 완화용 물질의 초고속스크리닝 기법 개발)

  • Heo Jin-Chul;Park Ja-Young;Kwon Taeg Kyu;Chung Shin Kyo;Kim Sung-Uk;Lee Sang-Han
    • Food Science and Preservation
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    • v.12 no.3
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    • pp.267-274
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    • 2005
  • Oxidant stress is a well-known pivotal parameter for the degenerative immune diseases including asthma, atopic dermatitis, and rhinitis. In order to screen for anti-asthma agents effectively, we first established the infrastructure of high throughput screening(HTS) for anti-oxidant agents from agricultural products and/or oriental medicine library extracted with water, methanol, dimethyl sulfoxide, ethyl acetate and juice, Using the screening system, we found that Chaenomelis langenariae, Rhus javanica L., Camellia sinensis, Helianthus annuus and Angelica utilis Makino had strong anti-oxidant activity. Moreover, Helianthus annuus, Rehmannia glutinosa Libo and Angelica utilis Makino have protection activities by treatment of an oxidant hydrogen peroxide. Together, these results suggest that screened agents could be potential agents against asthma, although the in vivo studies should be clearly tested.

Performance Analysis of 800Gb/s ATM Switching MCM (800Gb/s ATM 스위칭 MCM의 성능분석)

  • Jung, Un-Suk;Kim, Hoon;Park, Kwang-Chae
    • Proceedings of the IEEK Conference
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    • 2001.06a
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    • pp.155-158
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    • 2001
  • A 640Gb/s high-speed ATM switching system that is based on the technologies of advanced MCM, 0.25um CMOS and optical WDM interconnection is fabricated for future N-ISDN services. A 40 layer, 160mm$\times$114mm ceramic MCM realizes the basic ATM switch module with 80Gbps throughput. The basic unit ATM switch module with 80Gb/s throughput. The basic unit ATM switch MCM consists of in 8 chip advanced 0.25um CMOS VLSI and 32 chip I/O Bipolar VLSIs. The MCM employs an 40 layer, very thin layer ceramic MCM and a uniquely structured closed loop type liquid colling system is adopted to cope with the MCM's high-power dissipation of 230w. The MCM is Mounted on a 32cm$\times$50cm mother board. A three stage ATM switch is realized by optical WDM interconnection between the high-performance MCM.

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Analysis of Hybrid ARQ System Using Cross Layer (Cross Layer를 이용한 Hybrid ARQ System 분석)

  • Park, Tae-Doo;Kim, Min-Hyuk;Kim, Chul-Seong;Jung, Ji-Won
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.21 no.11
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    • pp.1229-1234
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    • 2010
  • High quality and high speed multimedia services will be required in the next generation mobile communications. To satisfy these services, powerful error correction techniques are used. ARQ(Auto Repeat Request) techniques, aspects of the throughput, and FEC(Forward Error Correct) techniques have disadvantages in terms of reliability. H-ARQ(Hybrid Auto Repeat Request) systems have been studied extensively as a solution of these disadvantages. In this paper introduce double layer coding and H-ARQ type, proposed H-ARQ system using double layer coding methods. Simulate BER performance and throughput. And we suggest that according to channel condition suitable H-ARQ type.