• Title/Summary/Keyword: high speed forming

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Cytotoxic Effect of Urushiol on Human Ovarian Cancer Cells

  • Choi, Ju-Youn;Park, Chang-Soo;Choi, Jong-Oh;Rhim, Hyang-Shuk;Chun, Heung-Jae
    • Journal of Microbiology and Biotechnology
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    • v.11 no.3
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    • pp.399-405
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    • 2001
  • Urushiol, a natural pro-electrophilic quinone compound, has potential structural characteristics as antitumor chemotherapeutic agents. However, urushiol's use as an antitumor drug has some problems, because it is hardly miscible with an aqueous solution. Purified urushiol is highly viscous and soluble only in strong solvents. for this study, we prepared an urushiol-ethanol micro-emulsion with a unimodal size distribution by high-speed homogenization. This generated effective delivery of urushiol to its action wites, so that we could investigate its cytotoxic activity against cancer cells. Using a colony-forming assay, we were able to show that urushiol selectively inhibited the growth of the ovarian cancer cells PA-1 and 2774 at a concentration of $10^{-6}$, whereas it had only a negligible effect on normal CHO cells at the same concentration. The data suggest that urushiol may have potential as an effective antitumor agent in the treatment of ovarian cancer. In addition, we addressed the question of whether the specific cytotoxic effect of urushiol is linked to apoptosis, by DNA fragmentation and DAPI staining assays. The inhibitory effects of urushiol on the growth of ovarian cancer cells was found to be associated with DNA fragmentation and the fragmented nuclei formation, both of which represent markers for the induction of apoptosis. Therefore, the results suggested that urushiol affected its profound cytotoxicity by triggering apoptosis in ovarian cancer cells.

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A Novel Equalization Method of Multiple Transceivers of Multiple Input Multiple Output Antenna for Beam-farming and the Estimation of Direction of Arrival (빔조향 및 전파도래각 추정을 위한 새로운 다중입력 다중출력 안테나 송수신부 구성방법)

  • 이성종;이종환;염경환;윤찬의
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.13 no.3
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    • pp.288-300
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    • 2002
  • In this paper, a novel method of equalization of RF transceivers is suggested for MIMO(Multiple Input Multiple Output) antenna actively studied for high speed data transmission in the recent IMT-2000 system. The core of suggestion is in equalizing the transfer characteristics of multiple transceivers using feedback and memory during the predefined calibration time. This makes it possible to weight the signals in the intermediate frequency, which is easier in the application of recently developed DoA(Direction of Arrival) algorithms. In addition, the time varying optimum cell formation according to traffic is feasible by antenna beam-forming based on the DoA information. The suggested method of equalizing multiple transceivers are successfully verified using envelope simulation. two outputs. This paper is concerned with the diagnosis of multiple crosstalk-faults in OSM. As the network size becomes larger in these days, the convent.nal diagnosis methods based on tests and simulation be.me inefficient, or even more impractical. We propose a simple and easily implementable alg?ithm for detection and isolation of the multiple crosstalk-faults in OSM. Specifically, we develop an algorithm for isolation of the source fault in switc.ng elements whenever the multiple crosstalk-faults are.etected in OSM. The proposed algorithm is illustrated by an example of 16$\times$16 OSM.

The Effects of Fuel Temperature on the Spray and Combustion Characteristics of a DISI Engine (직접분사식 가솔린 엔진에서 연료 온도에 따른 팬형 분무 및 연소 특성의 변화)

  • Moon, Seok-Su;Abo-Serie, Essam;Bae, Choong-Sik
    • Transactions of the Korean Society of Automotive Engineers
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    • v.14 no.3
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    • pp.103-111
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    • 2006
  • The spray behavior of direct-injection spark-ignition(DISI) engines is crucial for obtaining the required mixture distribution for optimal engine combustion. The spray characteristics of DISI engines are affected by many factors such as piston bowl shape, air flow, ambient temperature, injection pressure and fuel temperature. In this study, the effect of fuel temperature on the spray and combustion characteristics was partially investigated for the wall-guided system. The effect of fuel temperature on the fan spray characteristics was investigated in a steady flow rig embodied in a wind tunnel. The shadowgraphy and direct imaging methods were employed to visualize the spray development at different fuel temperatures. The microscopic characteristics of spray were investigated by the particle size measurements using a phase Doppler anemometry(PDA). The effect of injector temperature on the engine combustion characteristics during cold start and warming-up operating conditions was also investigated. Optical single cylinder DISI engine was used for the test, and the successive flame images captured by high speed camera, engine-out emissions and performance data have been analyzed. This could give the way of forming the stable mixture near the spark plug to achieve the stable combustion of DISI engine.

Design and Construction of the Burj Dubai Concrete Building Project (버즈 두바이 콘크리트 건물의 설계와 시공)

  • Abdelrazaq, Ahmad
    • Magazine of the Korea Concrete Institute
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    • v.20 no.6
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    • pp.28-35
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    • 2008
  • The Burj Dubai Project will be the tallest structure ever built by man; when completed the tower will be more than 700 meter tall and more than 160 floors. While the early integration of aerodynamic shaping and wind engineering considerations played a major role in the architectural massing and design of this multi-use/residential tower, where mitigating and taming the dynamic wind effects was one of the most important design criteria, the material selection for the structural systems of the tower was also a major consideration and required detailed evaluation of the material technologies and skilled labor available in the market at the time Concrete was selected for its strength, stiffness, damping, redundancy, moldability, free fireproofing, speed of construction, and cost effectiveness. In addition, the design challenges of using concrete for the design of the structural system components will be addressed. The focus on this paper will also be on the early planning of the concrete works of the Burj Dubai Project.

Analysis of CAD Design and Physical Properties of Double-raschel Spacer Fabric (더블라셀 소재의 CAD에 의한 표현과 물성연구)

  • Choi, Kyoungme;Kim, Jongjun
    • Journal of Fashion Business
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    • v.23 no.1
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    • pp.37-48
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    • 2019
  • WKSF (Warp-knitted spacer fabrics) knitted using a double Raschel machine is the three-dimensional knit that has vertically connected separate layers in loop structures. Because of its unique structure, the fabric is light, compressible and breathable. Owing to the high production speed, the use of the fabric is increasing in various areas. The purpose of this study is to establish the design process in the utilization of WKSF program and analyze the difference between WKSF and Neoprene as garment materials.. The study on the design related to WKSF has rarely been carried out because of the complexity of WKSF structure and the difficulties encountered in analyzing the structure and thread. Therefore, checking beforehand the simulation results similar to a final knit using the CAD program for WKSF can only enhance the efficiency of the design for the light knits. The conclusion drawn after designing the light knits using the CAD program and analyzing the pros and cons of WKSF through the various property evaluation techniques is as follows. The tension characteristic analysis results indicated that Neoprene specimen has the elastic transformation and resilience, thus behaving like an elastic product such as rubber. By contrast, in the event that clothing and fashion accessories are designed with WKSF, these products are kept in a boxy style fit so that the fabric can be applied flexibly to a curvy body line. In addition, WKSF is good in forming noticeably around a curvy body, because its resistance shear deformation is lower than that of Neoprene.

Microstructural Analysis of STS316L Samples Manufactured by Powder Bed Fusion and Post-heat Treatments (Powder Bed Fusion 공정으로 제조한 STS 316L의 미세조직과 후속 열처리 특성)

  • Song, S.Y.;Lee, D.W.;Cong, D.V.;Kim, J.W.;Lee, S.M.;Joo, S.H.;Kim, Jin-Chun
    • Journal of Powder Materials
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    • v.29 no.1
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    • pp.14-21
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    • 2022
  • In the powder bed fusion (PBF) process, a 3D shape is formed by the continuous stacking of very fine powder layers using computer-aided design (CAD) modeling data, following which laser irradiation can be used to fuse the layers forming the desired product. In this method, the main process parameters for manufacturing the desired 3D products are laser power, laser speed, powder form, powder size, laminated thickness, and laser diameter. Stainless steel (STS) 316L exhibits excellent strength at high temperatures, and is also corrosion resistant. Due to this, it is widely used in various additive manufacturing processes, and in the production of corrosion-resistant components with complicated shapes. In this study, rectangular specimens have been manufactured using STS 316L powder via the PBF process. Further, the effect of heat treatment at 800 ℃ on the microstructure and hardness has been investigated.

Modeling and experimental verification of phase-control active tuned mass dampers applied to MDOF structures

  • Yong-An Lai;Pei-Tzu Chang;Yan-Liang Kuo
    • Smart Structures and Systems
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    • v.32 no.5
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    • pp.281-295
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    • 2023
  • The purpose of this study is to demonstrate and verify the application of phase-control absolute-acceleration-feedback active tuned mass dampers (PCA-ATMD) to multiple-degree-of-freedom (MDOF) building structures. In addition, servo speed control technique has been developed as a replacement for force control in order to mitigate the negative effects caused by friction and inertia. The essence of the proposed PCA-ATMD is to achieve a 90° phase lag for a structure by implementing the desired control force so that the PCA-ATMD can receive the maximum power flow with which to effectively mitigate the structural vibration. An MDOF building structure with a PCA-ATMD and a real-time filter forming a complete system is modeled using a state-space representation and is presented in detail. The feedback measurement for the phase control algorithm of the MDOF structure is compact, with only the absolute acceleration of one structural floor and ATMD's velocity relative to the structure required. A discrete-time direct output-feedback optimization method is introduced to the PCA-ATMD to ensure that the control system is optimized and stable. Numerical simulation and shaking table experiments are conducted on a three-story steel shear building structure to verify the performance of the PCA-ATMD. The results indicate that the absolute acceleration of the structure is well suppressed whether considering peak or root-mean-square responses. The experiment also demonstrates that the control of the PCA-ATMD can be decentralized, so that it is convenient to apply and maintain to real high-rise building structures.

An Assessment Study on Stability of Various Coating Treatment of Metallic Artifacts Using V-Flon (불소 수지(V-Flon)를 이용한 금속유물의 코팅 형성에 대한 안전성 평가 연구)

  • Lee, Jung-Min;Wi, Koang-Chul
    • Journal of Conservation Science
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    • v.26 no.2
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    • pp.149-156
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    • 2010
  • One of resins, V-Flon is useful as a coating material because YK-D80, which is a solvent for V-Flon, is not highly volatile. However, it can not completely harden and can flow out when metal artifacts are joined and restored in the process of the treatment. Therefore, after the impregnation process in order to accelerate the hardening speed of a coating material, usually a dry oven was adopted. This study focused on finding the problems on the dry oven which is employed to increase the speed and investigating the most effective solvent and its composition by checking any change occurred depending on the concentration of solvents. Six different types of solvents were selected and samples were prepared in a manner that they were impregnated with solvents in three concentrations respectively (10%, 20%, 30%). To determine the condition of the samples, the stability evaluation was performed by measuring the change of color and the gloss, the thickness of coated layers, the corrosion after coating, the water resistance by contact angles. Through the comparative experiments between the natural drying and the artificial drying using a dry oven, it was found that when the dry oven is used, some problems are identified on the point of forming a uniform and stable layer because of the unstable data collected from the forced artificial dry. The experiments performed using 3 different concentration rates (10%, 20%, 30%) presented that in the case of 10% V-Flon in Xylene (using as a solvent), its layer was thin as well as it showed the high water-barrier property, which allows it to form the stably coated layer with the lower gloss and color change.

Gas Exchanges and Dehydration in Different Intensities of Conditioning in Tifton 85 Bermudagrass: Nutritional Value during Hay Storage

  • Pasqualotto, M.;Neres, M.A.;Guimaraes, V.F.;Klein, J.;Inagaki, A.M.;Ducati, C.
    • Asian-Australasian Journal of Animal Sciences
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    • v.28 no.6
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    • pp.807-815
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    • 2015
  • The present study aimed at evaluating the intensity of Tifton 85 conditioning using a mower conditioner with free-swinging flail fingers and storage times on dehydration curve, fungi presence, nutritional value and in vitro digestibility of Tifton 85 bermudagrass hay dry matter (DM). The dehydration curve was determined in the whole plant for ten times until the baling. The zero time corresponded to the plant before cutting, which occurred at 11:00 and the other collections were carried out at 8:00, 10:00, 14:00, and 16:00. The experimental design was randomised blocks with two intensities of conditioning (high and low) and ten sampling times, with five replications. The high and low intensities related to adjusting the deflector plate of the free iron fingers (8 and 18 cm). In order to determine gas exchanges during Tifton 85 bermudagrass dehydration, there were evaluations of mature leaves, which were placed in the upper middle third of each branch before the cutting, at every hour for 4 hours. A portable gas analyser was used by an infrared IRGA (6400xt). The analysed variables were photosynthesis (A), stomatal conductance (gs), internal $CO_2$ concentration (Ci), transpiration (T), water use efficiency (WUE), and intrinsic water use efficiency (WUEi). In the second part of this study, the nutritional value of Tifton 85 hay was evaluated, so randomised blocks were designed in a split plot through time, with two treatments placed in the following plots: high and low intensity of cutting and five different time points as subplots: cutting (additional treatment), baling and after 30, 60, and 90 days of storage. Subsequently, fungi that were in green plants as well as hay were determined and samples were collected from the grass at the cutting period, during baling, and after 30, 60, and 90 days of storage. It was observed that Tifton 85 bermudagrass dehydration occurred within 49 hours, so this was considered the best time for drying hay. Gas exchanges were more intense before cutting, although after cutting they decreased until ceasing within 4 hours. The lowest values of acid detergent insoluble nitrogen were obtained with low conditioning intensity after 30 days of storage, 64.8 g/kg DM. The in vitro dry matter of Tifton 85 bermudagrass did not differ among the storage times or the conditioning intensities. There was no fungi present in the samples collected during the storage period up to 90 days after dehydration, with less than 30 colony forming units found on plate counting. The use of mower conditioners in different intensities of injury did not speed up the dehydration time of Tifton 85.

Comparative analysis of cutting performance for basalt and granite according to abrasive waterjet parameters (연마재 워터젯 변수에 따른 현무암 및 화강암 절삭성능 비교분석)

  • Park, Jun-Sik;Cha, Hyun-Jong;Jo, Seon-Ah;Jung, Ju-Hwan;Oh, Tae-Min
    • Journal of Korean Tunnelling and Underground Space Association
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    • v.24 no.5
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    • pp.395-409
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    • 2022
  • To overcome the limitation of conventional rock excavation methods, the excavation with abrasive waterjet has been actively developed. The abrasive waterjet excavation method has the effect of reducing blasting vibration and enhancing the excavation efficiency by forming a continuous free surface on the rock. However, the waterjet cutting performance varies with rock fracturing characteristics. Thus, it is necessary to analyze the cutting performance for various rocks in order to effectively utilize the waterjet excavation. In this study, cutting experiments with the high pressure waterjet system were performed for basalt and granite specimens. Water pressure, standoff distance, and traverse speed were determined as effective parameters for the abrasive waterjet cutting. The cutting depth and width of basalt specimens were analyzed to compare with granite results. The averaged cutting depth of basalt was shown in 41% deeper than granite; in addition, the averaged cutting width of basalt was formed by 18.5% narrower than granite. The results of this study are expected to be useful basic data for applying rock excavation site with low strength and high porosity such as basalt.