• Title/Summary/Keyword: herniated lumbar disc patients

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Different Expression of Extracellular Matrix Genes: Primary vs. Recurrent Disc Herniation

  • Kuh, Sung-Uk;Kwon, Young-Min;Chin, Dong-Kyu;Kim, Keun-Su;Jin, Byung-Ho;Cho, Yong-Eun
    • Journal of Korean Neurosurgical Society
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    • v.47 no.1
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    • pp.26-29
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    • 2010
  • Objective: Recurrent lumbar disc herniation has been reported to occur in 5% to 15% of surgically treated primary lumbar disc herniation cases. We investigated the molecular biologic characteristics of primary herniated discs and recurrent discs to see whether the recurrent discs has the similar biological features with primary herniated discs. Methods: Primary hemiated disc and recurrent disc cells were obtained by discectomy of lumbar disc patients and cells were isolated and then taken through monolayer cultures. We compared chondrogenic and osteogenic mRNA gene expression, and western blot between the two groups. Results: The mRNA gene expression of recurrent disc cells were increased 1.47* times for aggrecan, 1.38 times for type I collagen, 2.04 times for type II collagen, 1.22 times for both Sox-9 and osteocalcin, and 1.31 times for alkaline phosphatase, respectively, compared with the primary herniated lumbar disc cells (*indicates p < 0.05). Westem blot results for each aggrecan, type I collagen, type II collagen, Sox-9, osteocalcin, and alkaline phosphatase were similar between the primary herniated disc cells and recurrent disc cells. Conclusion: These results indicate that the recurrent disc cells have similar chondrogenic and osteogenic gene expression compared to primary herniated disc cells. Therefore, we assumed that the regeneration of remaining discs could fill the previous discectomy space and also it could be one of the factors for disc recurrence especially in the molecular biologic field.

Effectiveness of ShinBaro Pharmacopuncture on Lumbar Spinal Herniated Intervertebral Disc : A Randomized Controlled Trial (요추추간판탈출증에 대한 신바로약침의 효과 : 무작위 대조군 시험)

  • Jun, Byung-Chul;Kim, Eun-Soo;Kim, Dong-Sub;Kim, Tae-Hun;Kim, Jee-Yong
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.6 no.2
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    • pp.109-119
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    • 2011
  • Objective : The aim of this study is to investigate the effectiveness of ShinBaro Pharmacopuncture in the treatment of patients with Lumbar spine Herniated Nucleus Pulposus. Methods : We investigated 20 cases of patients with lumbar disc herniation and devided into two groups. Experimental group were treated with ShinBaro Pharmacopuncture with integrated package treatment and control group were treated the same therapies without ShinBaro Pharmacopuncture. To evaluate the treatment effects of two groups, we used numeric rating scale(NRS), oswestry disability index(ODI). Results : In NRS of lumbar and sciatica pain and ODI, that of experimental group was much more improved than control group, and decrement of NRS of lumbar pain showed statistical significance along with the duration of treatment. Conclusions : ShinBaro Pharmacopuncture was thought to be effective for relieving symptoms of lumbar spine herniated nucleus pulposus, although further study is needed.

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The disc morphological changes on CT scan examinations after 5-7years, of acute HIVD patients who underwent oriental medical treatment (조기(早期) 한방치료(韓方治療)를 시행한 요추수핵탈출증(腰椎髓核脫出症) 환자(患者)의 C-T 상(上) 5-7년 후의 추간판(椎間板)의 변화(變化))

  • Mun, Hyung-Cheal;Hwang, Woo-Jun;Lee, Geon-Mok;Cho, Nam-Geun;Gang, Sung-Do;Cho, Jae-Woon;Chang, Byoung-Sun;Jin, Kyong-Son
    • Journal of Acupuncture Research
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    • v.18 no.4
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    • pp.1-12
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    • 2001
  • Study design : A retrospective study of lumbar disc herniations using results of follow-up computed tomographic scan examinations. Objective : Lumbar disc herniations is one of the cause low back pain and lower extremity pain. To clarify the lumbar disc herniations morphological changes over time(mean 5.3 years) in order to establish a strategy for treatment. Methods : Sixteen patients with lumbar disc herniations who underwent follow-up computed tomographic scan examinations were studied. The changes over time in herniated disc size(herniation ratio) were evaluated using this scan technique. The initial computed tomographic scan allowed classification of the herniations according to herniation ratio: small, medium and large. Results : Comparison with follow-up computed tomographic scans showed that of the 16 patients, in 14 patients(88%), the herniation ratio(HR) was decreased and among them, 8 patients had complet resolution of herniated disc. In 2 patients with small herniations, the HR of one case was increased, the other was decreased. In 8 patients with medium herniations, the HR of one case had no change, the others was decreased. In 6 patients with large herniation, the HR of all patients was decreased. Interestingly, 4 of the 16 patients showed calcification change of herniated disc. Conclusion : There is no doubt that herniated disc size is decreased over time. The largest herniations were those which had the greatest tendency to decrease in size. But in some cases, the HR was increased, or calcification change was showed.

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A Clinical Study for Patients with Lumbar Disc Herniation: Association Between Clinical Outcomes of Conservative Treatment and Cigarette Smoking (요추 추간판 탈출증 환자의 보존적 치료결과와 흡연의 상관성에 대한 임상적 고찰)

  • Bahn, Hyo-Jung;Kim, Seok;Yoon, Hyun-Seok;Kim, Han-Kyum;Kim, Sun-Min;Kim, Jee-Yang;Kim, Tae-Hun;Park, Byoung-Yoon
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.5 no.2
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    • pp.17-32
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    • 2010
  • Objectives : To investigate the association between cigarette smoking and clinical outcomes of conservative treatment for lumbar herniated disc. Methods : We reviewed 74 male patients with lumbar herniated disc who were hospitalized at the Jaseng Oriental Medicine Hospital. 74 patients were divided into 2 groups(smokers, non-smokers) and we measured age, ODI score, SF-36 score, VAS. Results : Between smokers and non-smokers, statically significant differences were found in clinical symptoms on the time of 6 months later, effective scores of treatments, value of ODI and value of VAS on the time of 6 months later. And in these values of measurements, non-smokers were higher than those of smokers. Conclusion : These results suggest that possibility of the association between cigarette smoking and clinical outcomes of conservative treatment for lumbar herniated disc.

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Clinical Study on 32 Patients of Lumbar Herniated Intervertebral Disc with Spondylolisthesis (척추전방전위증을 동반한 요추간판 탈출증 환자 32례에 대한 한의학적 임상고찰)

  • Lee, Han;Jung, Ho-Suk;Kim, Sang-Joo;Kim, Eun-Seok;Han, Kyung-Wan;Woo, Jae-Hyuk;Lee, Joon-Seok;Lee, Seul-Ji;Lee, Seon-Goo;Cha, Yun-Yeop
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.6
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    • pp.1087-1093
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    • 2010
  • The purpose of this study is to survey the effectiveness of oriental medicine treatment on lumbar herniated intervertebral disc and spondylolisthesis. The clinical study was performed on 32 cases of patients with lumbar herniated intervertebral disc and spondylolisthesis as diagnosed by X-ray, Magnetic resonance imaging(MRI) exams amongst the patients who were admitted to Jaseng Hospital of Oriental Medicine from January 2010 to June 2010. 32 cases of patients were analyzed according to the distribution of sex, age, duration of disease, contributory factor, symptoms, admission period, disc herniation type and level of spondylolisthesis. The efficacy of treatment was evaluated respectively. The number of the female patients were larger than that of male with the ratio of 1:0.6. Most of the patients were in their fifties(43.8%), choronic phase(46.9%), those patients suffered from lower back pain and leg pain radiation(90.6%), reasons unknown(56.3%). Most of them also had mixed disc(37.5%), bulging disc(37.5%) and spondylolisthesis of LS on L5(50.0%). Most of them stayed in the hospital for 21-25days. After treatment, the percentage with good improvement was 62.5%, fair 18.8%, poor 12.5%, and excellent 6.3%, respectively. Oriental medicine treatment has on useful effect on the recovery of lumbar herniated intervertebral disc with spondylolisthesis.

The Effects of Intermittent Traction and Manual Traction on Lumbar Herniated Disc (간헐적 견인과 도수 견인이 요추 추간판 탈출에 미치는 효과)

  • Kwon, Won-An;Ma, Sang-Yeol;Hwang, Yoon-Tae
    • The Journal of Korean Physical Therapy
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    • v.21 no.3
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    • pp.9-16
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    • 2009
  • Purpose: The purpose of this study was to investigate the effects of intermittent lumbar traction and manual traction on a $L_{4-5}$ herniated disc. Method: The subjects were randomly divided into the intermittent lumbar traction group (n=10) and the manual traction group (n=10). The intermittent traction group had traction-treatment applied for 12 times in the first two weeks, and then 6 times in the next two weeks. The time the traction was applied was for 30 minutes. The manual traction group had flexion-distraction therapy applied for 12 times in first two weeks, and for 6 times in next two weeks. The time the traction was applied was 3 to 6 minutes per treatment. Results: The change of the muscle test (MT), the disc herniation index (DHI) and the sagittal $T_2$ weighted MRI was measured at pretreatment and 4weeks and 12weeks after treatment. Conclusion: We found that intermittent lumbar traction and manual traction could improved the MT and DHI and this could improve the rehabilitation of patients with lumbar herniated disc.

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A Case Report on a Patient with Acute Herniated Lumbar Disc due to Coughing Treated with Megadose Pharmacopuncture and Combined Korean Medicine (기침으로 급성 악화된 요추 추간판 파열 환자의 대용량 약침 및 복합 한방치료 호전사례 1례)

  • Ryu, Gwang-hyun;Moon, Heeyoung;Ju, Ah-ra;Choo, Won-jung;Choi, Yo-sup;Moon, Youngjoo;Chai, Jiwon;Shin, Wonbin
    • The Journal of Internal Korean Medicine
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    • v.40 no.6
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    • pp.1248-1258
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    • 2019
  • Objective: The purpose of this study was to report the radiological and symptomatic changes in a patient with acute herniated lumbar disc due to coughing, treated with megadose pharmacopuncture and combined Korean medicine. Methods: MRI examination diagnosed an acute lumbar disc herniation by coughing. We performed a combination treatment of megadose pharmacopuncture and integrated Korean medicine. NRS, ODI, EQ-5D, SLR test, and big toe extension test were checked on admission, after two weeks, on discharge, and after four months to confirm symptom improvements. Results: In the acute stage of lumbar intervertebral disc rupture, megadose pharmacopuncture combined with Korean medicine treatment showed improvement in NRS, ODI, EQ-5D, SLRT, and big toe extension tests. In addition, absorption of the herniated intervertebral discs was observed through an MRI scan on discharge. Conclusions: For patients with herniated lumbar disc acutely deteriorated by coughing, a combination of megadose pharmacopuncture with Korean medicine treatment may be a solution.

Spinal Nerve Root Swelling Mimicking Intervertebral Disc Herniation in Magnetic Resonance Imaging -A Case Report-

  • Kim, Yu-Yil;Lee, Jun-Hak;Kwon, Young-Eun;Gim, Tae-Jun
    • The Korean Journal of Pain
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    • v.23 no.1
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    • pp.51-54
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    • 2010
  • A herniated intervertebral disc is the most common type of soft tissue mass lesion within the lumbar spinal canal. Magnetic resonance imaging (MRI) is a useful tool for the assessment of patients with lower back pain and radiating pain, especially intervertebral disc herniation. MRI findings of intervertebral disc herniation are typical. However, from time to time, despite an apparently classic history and typical MRI findings suggestive of disc herniation, surgical exploration fails to reveal any lesion of an intervertebral disc. Our patient underwent lumbar disc surgery with the preoperative diagnosis of lumbar disc herniation; however, nothing could be found during the surgical procedure, except a swollen nerve root.

Clinical Case Report on Comparison Between 6 Herniated Lumbar Disc Patients Which Were Divided into Two Groups each Treated by Decompression Therapy and Chuna Treatment. (요추 추간판탈출증 환자 6례에 대한 감압치료와 추나치료의 비교 임상보고)

  • Pi, Chien-Hsin;Kim, Esther;Song, Yong-Sun;Kim, Dong-Eun
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.4 no.1
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    • pp.75-84
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    • 2009
  • Objective : The purpose of the study is to compare the effects and efficacy of both treatments. Methods : 2 groups were divided among 6 patients who admitted to Jeonju Wonkwang hospital attached to Wonkwang University from 2009. jan. 1 to 2009. feb. 28 were diagnosed as herniated lumbar disc by lumbar CT or MRI. Each groups were treated by decompression therapy and chuna traetment daily and were measured under visual analogue scale and ODI score starting from the day of admission, after 1week, and second week to compare the results. Results and Conclusions : Decompression therapy and chuna treatment both showed effects on treating the patients though chuna traetment apparently revealed to be slightly more efficient. Due to the lack of abundant clinical data it was not objective in a strict sense but it was clinically meaningful enough.

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Seven Cases Report on the Foot Drop Patients with Herniated Intervertebral Lumbar Disc by Muscle Energy Technique & Korean Traditional Medicine Therapy (근에너지기법 및 한방치료를 적용한 족하수를 동반한 요추추간판탈출증 환자 치험 7례)

  • Chung, Jai-Hyeon;Yun, Young-Ung;Cheong, Seong-Hyun;Kim, Tae-Ho;Choi, Young-Jun;Kim, Sin-Woong;Lee, Cha-Ro
    • The Journal of Churna Manual Medicine for Spine and Nerves
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    • v.9 no.1
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    • pp.27-37
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    • 2014
  • Objectives : The present study reports seven foot drop patients with herniated intervertebral lumbar disc treated by Muscle Energy Technique and Korean traditional medicine therapy. Methods : Seven foot drop patients with herniated intervertebral lumbar disc were treated by Muscle Energy Rechnique and Korean traditional medicine therapy and were assessed by Manual Muscle Test, numeric rating scale, and oswestry low back pain disability index. Results : Among seven foot drop patients, two cases showed complete recovery, three cases showed recovery over good grade, and two cases showed recovery over good grade after temporary weakness. numeric rating scale and oswestry low back pain disability index of all cases showed improvement. Conclusions : Seven foot drop patients with herniated intervertebral lumbar disc were treated by Muscle Energy Rechnique and Korean traditional medicine therapy and showed improvement. It is anticipated that this report benefits the future in depth study and clinical treatments on the foot drop symptom in korean medicine.

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