• The Journal of Korean Medicine
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• v.20 no.3 s.39
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• pp.3-8
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• 1999

This study was carried out to investigate the dose of prescription in Shanghanlun. To this end, literature research and a survey of several herbal medicines have been done. As a result, the weight of 1 liang (兩) is determined to be about 15g. Furthermore, we find that Jung-Kyung Jang, who compiled Shang-hanlun, used a great quantity of herbal medicines to treat critical conditions of iIInesses. Therefore application of Shang-hanIun s prescriptions according to the various conditions of patients must have changed the quantity of dosage.

• Korean Journal of Oriental Medicine
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• v.10 no.2
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• pp.63-72
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• 2004

The decocting method of herbal medicines is various with a prescription or herbal medicine's characteristics. But it has common principles by which effective elements can be easily extracted with synergistic actions of herbs and which the therapeutic effect of a medicine is amplified. When decocting a herbal medicine, the volume of water is an important factor. Fire for decocting drugs and decocting time are also important factors. The excessive water and unproper decocting time and temperature can reduce the effect of the decoction. Besides a better decoction can be obtained by squeeze. According to herbal medicine's characteristics and prescription, there are herbs that should be treated after a specific method. For example, decoct first and decoct later. It also affects the therapeutic if a right taking method is not carried out. Methods of taking drugs include both the time and the method. We can confirm these decocting and taking methods in the ancient medical literatures of herbal medicine. This article deals with these things in detail.

• Herbal Formula Science
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• v.25 no.2
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• pp.253-270
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• 2017

Ojectives : To indicate source of prescriptions in "Wenbingtiaobian" and draw pathologic consideration for differences between prescription and source. Methods : Analysed cause and mechanism of disease, pattern identification, treatment, prescriptions and medicinal herbs based on "Translation of Wenbingtiaobian", "Modern Shanhanlun", "Jinkuiyaolueyishi", "Medical collection of Yetianshi" and "Herbal Formula Science". Results : 64.5% of prescriptions in "Wenbingtiaobian" are derived from "Linzhengzhinanyian", "shanghanlun" or "Jinkuiyaolue". Prescriptions from "shanghanlun" or "Jinkuiyaolue" have been modified to fit for heat pattern differentiations, to expand or reduce their medicinal scope, to build up efficacy by adding cold herbs, herbs of nourishing yin, engendering fluid or outthrusting through the exterior, to diffuse water-dampness or warm yang by adding warm herbs. Prescriptions from "Linzhengzhinanyian" have been modified to eliminate cold-dampness, disperse and outthrust with lightness, tonify yin. Conclusions : Wenbingtiaobian" inherited "Linzhengzhinanyian", "shanghanlun" nd "Jinkuiyaolue" andchanged and developed them to cure the febrile disease in the aspect of prescription, mechanism of disease, pattern differentiation and treatment.

• Journal of Sasang Constitutional Medicine
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• v.28 no.1
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• pp.57-66
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• 2016

Objectives The purpose of this study is to report on the collecting status of the prospective clinical data, that is designed to find clinical factors for determining the constitutional prescription.Methods We collected the prospective clinical data of 1208 subjects in the 10 oriental hospitals and 2 oriental clinic, from September 2012 to July 2015. Subjects were diagnosed and prescribed by the Sasang Constitution specialist. We counted the usage frequency of each constitutional herbal formula. Besides we check the main chief complaints on each constitutional herbal formula.Results & Conclusions In TE type, Yeoldahanso-tang, Cheongsimnyeonja-tang were used in high frequency. In SE type, Palmulgunja-tang, Gwakhyangjunggi-san were used in high frequency. In SY type, Hyeongbangjihwang-tang, Yanggyeoksanhwa-tang were used in high frequency. The both of high frequency-prescriptions in TE types were for the Interiorheat disease, expecially liver-heat lung-dry symptomatology. The main chief complaint of high frequency-prescriptions was fatigue in every constitution. We hope that the process of constitutional prescription would be standardized through the subsequent researches.

• Herbal Formula Science
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• v.21 no.1
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• pp.91-98
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• 2013

Objective : The purpose of this study was to investigate the synergistic effect of Angelicae gigantis Radix (AG) and Lycii fructus (LF) ethanol extracts on skin-whitening effects. Method : LFAG extracts were prepared by extracting with 80% ethanol. The efficacy of LFAG was judged by measurement of cell viability, tyrosinase activity, melanin production, tyrosinase and microphthalmia-associated transcription factor (MITF) expression in B16F10 murine melanoma cells by lipopolysaccharides (LPS) treatment. Results : Each extract (LF or AG) inhibited the tyrosinase activity in a dose-dependent manner. The co-treatment of LFAG extracts ($25{\mu}g/mL$ LF plus $25{\mu}g/mL$ AG) markedly suppressed the LPS-induced cellular tyrosine activity, melanin production, tyrosinase and MMP-1 expression in B16F10 murine melanoma cells. These suppressive effects were synergistically increased by their combination. Conclusions : With these observations, we suggest that the extracts from Lycii fructus and Angelica gigantis Radix could be potent natural materials for whitening skin.

• Herbal Formula Science
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• v.17 no.2
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• pp.21-38
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• 2009

This report describes 86 prescriptions related to the use of Herba Schizonepetae main blended from Dongeuibogam. The following conclusions were drawn through investigations on the prescriptions that use Herba Schizonepetae as a key component. Prescriptions that Herba Schizonepetae was taken as a monarch drug are utilized for22 therapeutic purposes, for example, eye disease, abscess disease, head and tooth, and woman disease. In particular, 16.3% of prescriptions appear in the chapter of eye. Prescriptions that utilize Herba Schizonepetae as the main component are used in the treatment of eye, abscess and woman disease, head disease, tooth disease and they are also used for treating 56 different types of disease. Herba Schizonepetae is used in pathogenic factors such as wind and used in pathology related to the liver and stomach system. The dosage of Herba Schizonepetae is 1pun 3li(about 0.49g) to 4don(about 14g), however 5pun 3li(about 1.99g)~1don(about 3.75g) has been taken the most for clinical application. Bangpungtang and Saenglyosamultang are the most useful base prescriptions which use the Herba Schizonepetae as the main ingredient.

• Herbal Formula Science
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• v.10 no.2
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• pp.5-46
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• 2002

This report describes the studies as follows through the research into the data of Cimicifuga heraclefolia Komarov blended prescriptions from Donguibogam. Cimicifuga heracleifola Komarov blended prescriptions are utilized for 39 therapeutic ranges. such as in dentistry, onclology, and 16 therapeutic ranges occupy over 84% totally, from dentistry to nasal disease. Cimicifuga heracleifola Komarov blended prescriptions use in the symptpms resulting from dentistry, intestine, internal disease, and they are used 22 disease also. The main pathologies of Cimicifuga heracleifola Komarov blended prescriptions found weakness in the digestive system, heat of stomach, wind of stomach in the splanchnology, and pathologies of wind-heat, wind-moisture, cold, excluding they are using for energy-blood, weakness, internal disease. The actual amount of Cimicifuga heracleifola Komarov blended has a wide capacity from 2 pun to 5 don, 1 don is broadlly used by 26%. Through the research into the main factors that we know Cimicifuga heracleifola Komarov blended prescriptions are listed in Yangmyungkyung, as they are regularly used as disease treatment and increasing the level of the general energy of the body, relaxing a skin, increasing stamina, detoxication, eliminating tumor, widely.

• Journal of Sasang Constitutional Medicine
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• v.28 no.4
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• pp.338-349
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• 2016

Objectives This case study was about a Taeyangin patient with transient ischemic attack(TIA) due to vertebrobasilar insufficiency(VBI). In this study, we report the progress of mistreat with Taeyangin as Taeeumin and the improvement of symptoms after rediagnosis as Taeyangin. Methods Patient's chief complain was weakness of lower limbs, dysarthria and dizziness. Patient first time took Taeeumin prescription such as Chunghyulganggi-tang, Chunsimyonja-tang and Sanyakbopaewon-tang. After occuring side effects we changed the prescription to Taeyangin herbal medicine such as Ogapijangchuk-tang gagam and Mihudeungsikjang-tang gagam. Result and Conclusion Patient suffered from diarrhea by taking Taeeumin prescription and symptom was continue. After changing of prescription to Taeyangin herbal medicine, not only chief symptom but also original symptom was improved.

• Herbal Formula Science
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• v.23 no.2
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• pp.225-233
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• 2015

Objectives : The purpose of this study was to investigate the interpretation of the Pyeongwi-san(PWS) prescription in order to obtain the evidence for clinical applications. Methods and Result : We interpreted on the PWS-related contents based on 15 classic books, analyzed it according to followed categories ; origin, indication and precaution, usage, meaning of name, physiological and pathological situation of PWS, explain about each herbs. Conclusion : 1. PWS was first mentioned in the Bakjebang, its application was enhancing appetite. Application of PWS not only expanded digestive disease, infectious disease, and pain in articular, but also used to toniyfing drug. 2. Generous application method of PWS was ‘Sujunbok(水煎服)’. Pill preparation(丸劑) and decoction with salt(鹽湯劑) were also used 3. "Pyeongwi(平胃)“ in PWS means "flatten the stomach". There are some theory about methodology to "Pyeongwi (平胃)“, one is "drain the pathogen in stomach(敦阜說)”, other is "tonifying stomach's healthy qi(卑監說)“, the other is compromise theory. 4. Most medical literature related application situation of PWS to dampness(濕邪) in stomach. In Gangsulwongobangsunju, there are more detailed explain focused on metal qi(金氣), and fire qi(火氣) 5. Atractylodes japonica Koidz(蒼朮) drys dampness and fortifys the spleen, Magnolia officinalis Rehder(厚朴) eliminates dampness and treats fullness, Citrus reticulata Blanco(陳皮) moves and drains qi, Glycyrrhiza uralensis Fisch(甘草) tonify and harmonize in herbal formula

• The Journal of Internal Korean Medicine
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• v.44 no.1
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• pp.35-52
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• 2023

Objective: Internal injuries and consumptive disease have different causes, yet they can affect each other. The relationship and combination of prescription drugs in the clinical practice of internal injuries and consumptive disease were analyzed for various diseases of "Donguibogam" through network analysis. Methods: The prescriptions used in consumptive disease and internal injury were established by conducting a full survey on the papers extracted from Donguibogam. The R version 4.0.3 (2020-10-10) and the igraph and arules package were used to perform network analysis and association rule relationship mining analysis in the first and second prescription compositions. Results: The herb frequently used for internal injury was Glycyrrhizae Radix, while the herb combination frequently used was Citri Pericarpium-Glycyrrhizae Radix. For centrality, the main factor was generally Glycyrrhizae Radix. In the case of consumptive disease, the herb most frequently used was Angelicae Gigantis Radix, and the combination most frequently used was Rehmanniae Radix Preparata-Angelicae Gigantis Radix. In terms of centrality, it was Angelicae Gigantis Radix. As a result of the network analysis of herbal prescription frequency, each group was divided into three. Conclusion: The interrelationship between internal injury and consumptive disease prescription drugs may reveal the differences and similarities between internal injury and consumptive disease and may serve as a basis for the development of new drugs or materials that can enhance mutual effectiveness in the treatment of internal injury and consumptive diseases.