The Journal of Internal Korean Medicine (대한한방내과학회지)

The Society of Internal Korean Medicine (대한한방내과학회)
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Comparison of Herbs in Prescription Composition of Consumptive Disease and Internal Injury in Donguibogam Through Network Analysis

네트워크 분석을 통한 동의보감(東醫寶鑑) 내상(內傷)문과 허로(虛勞)문의 처방 구성 본초 비교

  • Chien-hsin Kuo (Maek korea Medicine Clinic) ;
  • Heung Ko (Dept. of Korean Internal Medicine, College of Korean Medicine, Se-Myung University) ;
  • Seon-mi Shin (Dept. of Korean Internal Medicine, College of Korean Medicine, Se-Myung University)
  • 곽건신 (맥한의원) ;
  • 고흥 (세명대학교 한의과대학 내과학교실) ;
  • 신선미 (세명대학교 한의과대학 내과학교실)
  • Received : 2023.03.19
  • Accepted : 2023.04.03
  • Published : 2023.03.30
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Abstract

Objective: Internal injuries and consumptive disease have different causes, yet they can affect each other. The relationship and combination of prescription drugs in the clinical practice of internal injuries and consumptive disease were analyzed for various diseases of "Donguibogam" through network analysis. Methods: The prescriptions used in consumptive disease and internal injury were established by conducting a full survey on the papers extracted from Donguibogam. The R version 4.0.3 (2020-10-10) and the igraph and arules package were used to perform network analysis and association rule relationship mining analysis in the first and second prescription compositions. Results: The herb frequently used for internal injury was Glycyrrhizae Radix, while the herb combination frequently used was Citri Pericarpium-Glycyrrhizae Radix. For centrality, the main factor was generally Glycyrrhizae Radix. In the case of consumptive disease, the herb most frequently used was Angelicae Gigantis Radix, and the combination most frequently used was Rehmanniae Radix Preparata-Angelicae Gigantis Radix. In terms of centrality, it was Angelicae Gigantis Radix. As a result of the network analysis of herbal prescription frequency, each group was divided into three. Conclusion: The interrelationship between internal injury and consumptive disease prescription drugs may reveal the differences and similarities between internal injury and consumptive disease and may serve as a basis for the development of new drugs or materials that can enhance mutual effectiveness in the treatment of internal injury and consumptive diseases.

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