• Journal of Korean Traditional Oncology
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• v.20 no.1
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• pp.81-88
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• 2015

Generally, normal cells synthesize adenosine triphosphate (ATP) through oxidative phosphorylation in the mitochondria. However, they produce ATP through lactic acid fermentation on hypoxic condition. Interestingly, many cancer cells rely on aerobic glycolysis for ATP generation instead of mitochondrial oxidative phosphorylation, which is termed as "Warburg effect". According to results from recent researches on differences of cancer cell metabolism from normal cell metabolism and because chemotherapy to suppress rapidly growing cells, as a side effect of cancer treatment, can still target healthy cells, there is merit in the development of small-molecule inhibitors targeting metabolic enzymes such as pyruvate dehydrogenase kinase (PDHK), lactate dehydrogenase (LDH) and monocarboxylate transporter (MCT). For new anticancer therapy, in this review, we show recent advances in study on cancer cell metabolism and molecules targeting metabolic enzymes which are importantly associated with cancer metabolism for cancer therapy. Furthermore, we would also like to emphasize the necessity of development of molecules targeting metabolic enzymes using herbal medicines and their constituents for anticancer drugs.

• Research in Community and Public Health Nursing
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• v.23 no.3
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• pp.244-255
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• 2012

Purpose: This study was to describe and develop the female university students' healthy dieting. Methods: The data were collected from 9 female students sampled from two universities. The grounded theory of Strauss and Corbin (1990) was applied. Results: As a result, 40 concepts, 16 subcategories, and seven categories were deduced from open coding. Emerged seven major categories were as followings: (1) Recognizing of general health condition, (2) Try to actively participate on social activities, (3) Searching for continuous healthy exercising methods, (4) Utilizing of social support system for healthy dieting, (5) Making an individual healthy rhythms, (6) Exhibiting abilities of self-control, (7) Charging self-confidences. The periods of process were divided into 4 stages, the phase of facing self-health, the phase of searching living conditions, the phase of developing individual strategies, and the phase of forming self-confidence. The core variable, "discovering self competencies" incorporated the relationship between and among all categories and explained the process. Conclusion: This study had described the process of healthy dieting of female university students in Korea. These findings have important implications for health promotion of the female university students and can be utilized as material for developing health programs.

• The Korean Journal of Food And Nutrition
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• v.30 no.1
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• pp.83-95
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• 2017

This study examined the socioeconomic factors that affect self-rated health (SRH) in healthy adults, and the relationship of SRH to health-related habits, serum biochemical indices, and nutritional intakes. Subjects consisted of 1,154 healthy adults without any known disease, aged 19 to 65 years (average age of 36.7), whose information was obtained from the 2013 Korean National Health and Nutritional Examination Survey data. Of these subjects, 73 rated themselves as 'very healthy,' 460 indicated that they were 'healthy,' 568 self-identified as 'ordinary', and 53 put themselves in the 'unhealthy' category. The proportion of subjects who chose 'unhealthy' was significantly increased with higher frequencies of disruptions in their daily lives (p<0.05), regret after drinking (p<0.05), smoking (p<0.001), and higher levels of stress (p<0.001). On the other hand, the proportion of subjects reported as 'very healthy' was significantly higher with regular intense (p<0.001) or moderate physical activities (p<0.05), regular walking (p<0.05), a perception of being 'normal' in their body image (p<0.01), a decrease of body weight more than 3 kg in the past year (p<0.05), and without risk factors for metabolic syndrome (p<0.05). Serum triglyceride level was lower, and 25-(OH) vitamin D content was significantly higher, in the 'very healthy' group as compared to the 'unhealthy' group (p<0.05). Dietary fiber and vitamin C intakes were significantly higher in the 'very healthy' group than 'unhealthy' group (p<0.05). The overall results suggest that a healthy lifestyle, including regular exercise, non-smoking, good stress management, and higher intakes of fiber and vitamin C, may be potential factors that affect one's positive perception of health.

• Journal of Veterinary Clinics
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• v.36 no.4
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• pp.219-224
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• 2019

The aim of this study was to evaluate the safety and effects of a soy lecithin-based supplement on the general health, skin condition, and blood lipid levels of dogs. Twenty-five, healthy, privately-owned dogs were enrolled in the study. Oral supplementation was administered for 8 weeks in the treatment group. Evaluation items included a thorough physical examination, owner responses to a questionnaire, blood analysis (CBC, CRP, serum chemistry, lipid profile). The results showed a significant improvement in amount of exercise, water intake, skin exfoliation in the treatment group (P < 0.05) but no significant changes in the other evaluation items, including no significant changes in blood component results following administration of the supplement. Most dogs well tolerated the treatment, and there were no serious adverse events. We suggest that soy lecithin has potential as a nutraceutical for the positive effect of general health condition such as activity and skin condition. Further studies are needed to establish the appropriate dose level and administration frequency of soy lecithin in dogs.

• Journal of Veterinary Clinics
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• v.39 no.2
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• pp.45-50
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• 2022

Vertebral left atrial size can be used as a radiographic tool to evaluate left atrial size in dogs. Vertebral left atrial size has been studied in dogs; however, few studies have been conducted on breed-specific differences in healthy dogs. To study the median vertebral left atrial size differences by breed and to investigate the association between age, sex, body condition score, thoracic depth-to-width ratio, and vertebral left atrial size. A total of 220 dogs of the following breeds: Maltese (n = 73), Beagle (n = 30), Poodle (n = 41), Shih-tzu (n = 44), and Mongrel (n = 32) were reviewed retrospectively. Sex, body weight, age, and body condition score of each dog were collected. Thoracic radiography was conducted for dorsoventral and right/left lateral views in all dogs to measure the vertebral heart score, vertebral left atrial size, and thoracic depth-to-width ratio. No significant differences in the median vertebral left atrial size were found among the breeds. There were no effects of sex, age, body condition score, and thoracic depth-to-width ratio on vertebral left atrial size. There was a significant positive correlation between the vertebral heart score and vertebral left atrial size. Breed, age, sex, and chest conformation did not correlate with vertebral left atrial size.

• Journal of the Korean Society of Fashion and Beauty
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• v.4 no.3 s.9
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• pp.18-24
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• 2006

Hair is the part of body which expresses man into more manlike. When we create some artworks, we need the most suitable material for the artworks. Similarity, the healthy scalp hair condition and treatment are required to keep our hair clean and healthy. And the improper condition of scalp hair prohibits our hair from normal growing, proceeds the alopecia(loss of hair) and double our physical and mental stresses. The necessity of health treatment of scalp hair which was damaged by frequent permanent hair wave and hair coloring is on the rise. This study will present how to control and treat the scalp hair and will check how we feel about the necessity of scalp hair treatment. This study finally shows that people think their scalp hair conditions are not normal and chemically treated hair in spite of their natural hair. However, most people think that the scalp hair treatment is very useful to their hair and this result enables us to predict the future market of the scalp hair treatment business will be growing day by day. We need to study further not only scalp hair treatment but also prevention stage in order to keep the healthy hair and will check how we feel about the necessity of scalp hair treatment.

• The Korea Journal of Herbology
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• v.35 no.5
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• pp.41-46
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• 2020

Objectives : According to 2013 statistics, the primary infertility rate is 13.5%. The current situation is much worse than that reported, so it is even emerging as a social problem. The purpose of this study is to analyze the 5 cases of successful infertility treatment with herbal treatment and to give hope to the infertile couple to become pregnant and to suggest the possibility of herbal treatment in infertility treatment. Methods : We administered Jokyungjongok-tang gamibang as a herbal medicine and treated with acupuncture, moxibustion. Treatment was done once or twice a week. The herbal medicines were taken 30 minutes after meals and 3 times a day. While taking the herbal medicine, they were prohibited from eating flour, pork, liquor, tobacco and coffee. Patient status was assessed by consultation through pulse, tongue and abdominal diagnosis. The diagnosis of pregnancy was confirmed by ultrasonography at hospitals and the success of the treatment was judged based on healthy birth. Results : Patients had common features, such as lower abdominal pain, menstrual cramps, and blood clots during menstruation. Herbal medicine combined with acupuncture, moxibustion improved patients' overall fatigue and reduced the body's coldness. Since then, the dysmenorrhea and blood clots have decreased, and the digestion condition has improved. Therefore they became pregnant and gave birth to a healthy baby. Conclusion : Jokyungjongok-tang gamibang was effective in improving the body's coldness and uterine condition and was successful in pregnancy and helped to give birth to a healthy baby.

• Journal of Technologic Dentistry
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• v.33 no.4
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• pp.467-478
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• 2011

Purpose: The purpose of this study was to analyze dental technician's job environment and health condition level and to examine its correlation. Methods: 250 dental technicians in Seoul, Incheon, and Jeonbuk area were selected. Survey was carried out from October 11, 2010 to November 25, 2010 by using self-administered questionnaire. As for the tools for this study, the structured questionnaire was used with its proven reliability and feasibility, and the questionnaire consisted of total 49 questions which included general attribute of subjects(14 questions), job Environment(13 questions) and health condition(22 questions). The data analysis was processed by computerized system with SPSS Win 17.0. Statistical analysis techniques included frequency, percentage, T-test, One-way ANOVA analysis and regression analysis. Results: As a result of analyzing the research subjects' job environment level, there was significant difference in the item of gender, working hours a day(Hour), healthy condition, job satisfaction level with dental technician, plan for task continuity in dental technician(P<0.05). The average in the job environment was indicated to be high with 2.85. As a result of analyzing the research subjects' health condition level, there was significant difference in the item of gender, task field, working hours a day(Hour), healthy condition, job satisfaction level, plan for task continuity(P<0.05). The average in the self health recognition was indicated to be high with 2.83. Conclusion: Correlation between job environment and health condition, all of variables were indicated to have reverse correlation, thereby having been shown that the worse job environment leads to the more physical subjective symptoms.

• The Journal of Korean Physical Therapy
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• v.33 no.1
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• pp.1-6
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• 2021

Purpose: This study examined the effects of heel insoles on the static balance and leg muscle activity and posture control strategy during external perturbation. Methods: Thirty healthy young men participated in the study. The subjects underwent two experimental conditions: 1) no heel insole condition (0cm) and 2) wearing heel insole condition (5cm). The static balance was measured using an I-Balance device, which measured the change in the center of gravity (COG). The onset time of muscle activation and muscle activation of the erector spinae (ES), hamstring (HAM), gastrocnemius (GCM) were measured using surface EMG electrodes to determine the change in posture control strategy during external perturbation. Results: The speed and distance of COG were significantly higher in the wearing heel insoles condition than the no heel insole condition (p<0.05). In addition, significant differences in the onset time of the GCM, HAM, and ES muscle activation were observed when there was no heel insole condition during external perturbation (p<0.017). On the other hand, no significant differences in the onset time of muscle activation were observed between GCM and HAM when wearing the heel insole condition during external perturbation (p<0.017). Moreover, muscle activation of the GCM was significantly higher in the wearing heel insoles condition than the no heel insole condition during external perturbation (p<0.05). Conclusion: These findings suggest that heel insoles may have disadvantages, and increased efforts are needed to maintain balance and change the posture control strategy during external perturbation.

• Korean Journal of Occupational Health Nursing
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• v.10 no.1
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• pp.41-54
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• 2001

This study was designed to assess the relationship between occupational stress and health status in a study group of 197 workers employed in four newspaper publishing companies, using a self-adminstrative questionnaire. The types of occupation of them were reporters(79), clerical workers(54), and engineers (64). The studies on workers' health have been focused mainly on the physical, chemical, and biological diseases in our country. Therefore, the study of mental health, especially of occupational stress, is to be carried out. I consider stress as a factor having an effect on the health status of the newspaper employees, who have been well known to have high stress due to time pressures. I expect that this research will be helpful not only for understanding of health status by occupation, but also for making clear the issues that have been raised continuously from the previous researches. The results of this study are as follows; 1. The mean values of stress by occupation were statistically significant; the reporters had the highest stress symptom scores, and the engineers had the lowest levels of stress. The mean values of stress symptoms were higher in the workers who had long working hours. 2. The health status by occupation showed significant differences in gastrointestinal systems and in depression. The clerical workers were healthier than the engineers in gastrointestinal systems, and the reporters were more depressed than the engineers in depression. 3. The health status by the general characteristics, there was a statistical significance as for a gender, marital status, and absenteeism in the gastrointestinal systems. The men, the married, and the workers who had not been absent were more healthy. Only absenteeism had an effect on the problems in optical-dermal systems and in oro-fecal systems. Gender, marital status, absenteeism, and working hours were related with health status : the men. the married, the workers who had not been absent, and the workers who had longer working hours were more healthy. In mental stability, gender had a significant effect : the men were more healthy than the women. In general condition, the men, the older, the married, and the workers who had not been absent were more healthy. 4. Stress level had an effect on the health status in the respiratory systems, optical-dermal systems, oro-fecal system, depression, mental stability, general condition, and health condition. The workers who perceived more stress had more problems in their health status. 5. In the results of the multiple regression analyses, age in the respiratory systems, absenteeism in the optical-dermal systems, occupation and absenteeism in the gastrointestinal systems and in the oro-fecal systems, gender in depression and in mental stability, gender, age, absenteeism, and working hours in the general condition, absenteeism in the health condition had an effect on the health status of the workers.