• Title/Summary/Keyword: hazards ratios

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Gamma spectrum denoising method based on improved wavelet threshold

  • Xie, Bo;Xiong, Zhangqiang;Wang, Zhijian;Zhang, Lijiao;Zhang, Dazhou;Li, Fusheng
    • Nuclear Engineering and Technology
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    • v.52 no.8
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    • pp.1771-1776
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    • 2020
  • Adverse effects in the measured gamma spectrum caused by radioactive statistical fluctuations, gamma ray scattering, and electronic noise can be reduced by energy spectrum denoising. Wavelet threshold denoising can be used to perform multi-scale and multi-resolution analysis on noisy signals with small root mean square errors and high signal-to-noise ratios. However, in traditional wavelet threshold denoising methods, there are signal oscillations in hard threshold denoising and constant deviations in soft threshold denoising. An improved wavelet threshold calculation method and threshold processing function are proposed in this paper. The improved threshold calculation method takes into account the influence of the number of wavelet decomposition layers and reduces the deviation caused by the inaccuracy of the threshold. The improved threshold processing function can be continuously guided, which solves the discontinuity of the traditional hard threshold function, avoids the constant deviation caused by the traditional soft threshold method. The examples show that the proposed method can accurately denoise and preserves the characteristic signals well in the gamma energy spectrum.

A Study on the Biological Hazards Exposure for Waste Handling Industries in Korea (국내 폐기물 취급업의 생물학적 인자 노출실태)

  • Park, Hyunhee;Park, Hae Dong;Lee, Inseop
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.22 no.4
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    • pp.265-275
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    • 2012
  • Objectives: The aim of this study was to investigate the distribution patterns and exposure concentrations of biological hazards in waste handling industries. Methods: We selected 3 recyclable waste sorting plants(RWS), 2 food recycling plants(FR), 1 landfill area(LA) and 1 waste incineration plant(WI). Total airborne bacteria and fungi were measured with single stage impactor and gelatin filters. Endotoxin and glucan were measured with polycarbonate filters in total and respirable dust. Results: The geometric mean of airborne bacterial concentration was the highest in FR($3,273CFU/m^3$), followed by LA, RWS, and WI as 1,334, 934, and $860CFU/m^3$. The fungal concentrations were 6,031, 5,052, 3,307, and $713CFU/m^3$ in RWS, WI, FR, and LA, respectively. By process, WI pit showed the highest concentrations of bacteria, fungi, and endotoxin, followed by inside of bulldozer in LA. The indoor to outdoor ratios of bacteria, fungi, endotoxin and glucan were 2.3, 4.0, 2.3, and 5.0 in RWS, 29.5, 4.9, 7.6, and 5.0 in FR, 5.3, 8.7, 26.8, and 9.5 in WI, respectively. Conclusions: We found that biological hazards, specifically bacteria in FR, fungi in RWS and endotoxin in WI pit and bulldozer at LA, should be controlled to prevent worker's respiratory diseases.

Experimental and numerical study of Persian brick masonry barrel vaults under probable structural hazards

  • Saeid Sinaei;Esmaeel Izadi Zaman Abadi;Seyed Jalil Hoseini
    • Structural Engineering and Mechanics
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    • v.87 no.4
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    • pp.317-332
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    • 2023
  • Understanding and analysing the behaviour and response of historical structures in the face of climate changes and environmental conditions is of utmost significance for their preservation. There are several structural hazards associated with climate and hydrology changes in the region, including the settlement of piers, the rotation of piers, and temperature changes. The present study investigates the experimental and numerical structural behaviour of skewed and non-skewed Persian brick masonry barrel vaults under various conditions. The external loading conditions included pier rotation in five modes, settlement, and temperature variations in four states. Initially, the experiments extracted the mechanical properties of the scaled materials. Then, three semi-circular brick barrel vaults were tested with gravitational loads. The outcomes were used to develop and validate the finite element model. Following the development of the finite element model, numerical and parametric studies were conducted on the effect of the aforementioned structural hazards on the response of brick masonry barrel vaults with various Persian geometries (semi-circular, drop pointed, and four-centred), angles of skew (0, 15, 30, and 45 degrees), and dimensional ratios. According to the findings, the fragility of masonry materials makes historical structures susceptible to failure under different loading. A brick barrel vault fails in the presence of minor rotation and settlement of the piers. The four-centred geometric shape has the lowest performance among the seven Persian geometries; therefore, its health monitoring and retrofitting should be prioritised. In Isfahan, Iran, temperature variations, particularly during the warm seasons, cause critical conditions in such structures.

The Comprehensive Proportional Hazards Model Incorporating Time-dependent Covariates for Water Pipes (상수관로에 대한 시간종속형 공변수를 포함한 포괄적 비례위험모형)

  • Park, Su-Wan
    • Journal of Korea Water Resources Association
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    • v.42 no.6
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    • pp.445-455
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    • 2009
  • In this paper proportional hazards models for the first through seventh break of 150 mm cast iron pipes in a case study area are established. During the modeling process the assumption of the proportional hazards for covariates on the hazards is examined to include the time-dependent covariate terms in the models. As a result, the pipe material/joint type and the number of customers are modeled as time-dependent for the first failure, and for the second failure only the number of customers is modeled as time-dependent. From the analysis on the baseline hazard functions the failure hazards are found to be generally increasing for the first and second failure, while the hazards of the third break and beyond showed a form of a bath-tub. Furthermore, the changes in the baseline hazard rates according to the time and number of break reflect that the general condition of the pipes is deteriorating. The factors causing pipe break and their effects are analyzed based on the estimated regression coefficients and their hazard ratios, and the constructed models are verified using the deviance residuals of the models.

Areal Distribution Ratio of Rock ffes with Geologic Ages in the Gyeonggi-Seoul-Incheon Areas (경기-서울-인천지역 구성암류의 지질시대별 분포율)

  • Yun, Hyun-Soo;Lee, Jin-Young;Yang, Dong-Yoon;Hong, Sei-Sun
    • The Journal of the Petrological Society of Korea
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    • v.16 no.4
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    • pp.208-216
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    • 2007
  • Based on digital geologic and geomorphic maps of 1 : 250,000 scale, distributive ratios of rock types were obtained by ArcGIS 9.0 program in the Gyeonggi, Seoul and Incheon areas of the Gyeonggi province. In the Gyeonggi area, 37 rock types are developed, and their geologic ages can be classified into Precambrian, Age-unknown, Triassic, Jurassic, Cretaceous and Quatemary. Among them, distributive ratios are decreasing in the order of Jurassic Daebo granites, Precambrian banded gneiss of Gyeonggi gneiss complex and Quatemary alluvium, all of which comprise about 83.7% of the rock types in the area. In the Seoul and Incheon areas, 10 and 15 rock types are developed, respectively., with the firmer being classified into Precambrian, Jurassic and Quatemary, and the latter into Precambrian, Jurassic, Cretaceous and Quatemary. In the Seoul area, distributive ratios are decreasing in the order of banded gneiss of Gyeonggi gneiss complex, Daebo granites and alluvium, which consist of 95.5% of the rocks in the area. In the Incheon area, distributive ratios are decreasing in the order of alluvium, Daebo granites, banded gneiss of Gyeonggi gneiss complex, reclaimed land, and schists of Gyeonggi gneiss complex, which occupy about 96.2% of the rocks in the area. The ratio of alluvium in the Incheon area is greater than that of Gyeonggi and Seoul areas, and the ratio of reclaimed land in the Incheon area is greater that of the Seoul, which can be attributed to the recent reclamation of the land for the industrial results such as new town development along the coastline of the Gyeonggi Bay.

Expression Profiles of Loneliness-associated Genes for Survival Prediction in Cancer Patients

  • You, Liang-Fu;Yeh, Jia-Rong;Su, Mu-Chun
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.185-190
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    • 2014
  • Influence of loneliness on human survival has been established epidemiologically, but genomic research remains undeveloped. We identified 34 loneliness-associated genes which were statistically significant for high-lonely and low-lonely individuals. With the univariate Cox proportional hazards regression model, we obtained corresponding regression coefficients for loneliness-associated genes fo individual cancer patients. Furthermore, risk scores could be generated with the combination of gene expression level multiplied by corresponding regression coefficients of loneliness-associated genes. We verified that high-risk score cancer patients had shorter mean survival time than their low-risk score counterparts. Then we validated the loneliness-associated gene signature in three independent brain cancer cohorts with Kaplan-Meier survival curves (n=77, 85 and 191), significantly separable by log-rank test with hazard ratios (HR) >1 and p-values <0.0001 (HR=2.94, 3.82, and 1.78). Moreover, we validated the loneliness-associated gene signature in bone cancer (HR=5.10, p-value=4.69e-3), lung cancer (HR=2.86, p-value=4.71e-5), ovarian cancer (HR=1.97, p-value=3.11e-5), and leukemia (HR=2.06, p-value=1.79e-4) cohorts. The last lymphoma cohort proved to have an HR=3.50, p-value=1.15e-7. Loneliness-associated genes had good survival prediction for cancer patients, especially bone cancer patients. Our study provided the first indication that expression of loneliness-associated genes are related to survival time of cancer patients.

Effects of Smoking on Menopausal Age: Results From the Korea National Health and Nutrition Examination Survey, 2007 to 2012

  • Yang, Hee Jung;Suh, Pae Sun;Kim, Soo Jeong;Lee, Soon Young
    • Journal of Preventive Medicine and Public Health
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    • v.48 no.4
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    • pp.216-224
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    • 2015
  • Objectives: Decreased fertility and impaired health owing to early menopause are significant health issues. Smoking is a modifiable health-related behavior that influences menopausal age. We investigated the effects of smoking-associated characteristics on menopausal age in Korean women. Methods: This study used data from the Korea National Health and Nutrition Examination Survey from 2007 to 2012. Menopausal age in relation to smoking was analyzed as a Kaplan-Meier survival curve for 11 510 women (aged 30 to 65 years). The risk of entering menopause and experiencing early menopause (before age 48) related to smoking were assessed using a Cox proportional hazards model. Results: The menopausal age among smokers was 0.75 years lower than that among non-smokers (p<0.001). The results of the Cox proportional hazards model showed pre-correction and post-correction risk ratios for entering menopause related to smoking of 1.26 (95% confidence interval [CI], 1.09 to 1.46) and 1.27 (95% CI, 1.10 to 1.47), respectively, and pre-correction and post-correction risk ratios for experiencing early menopause related to smoking of 1.36 (95% CI, 1.03 to 1.80) and 1.40 (95% CI, 1.05 to 1.85), respectively. Conclusions: Smokers reached menopause earlier than non-smokers, and their risk for experiencing early menopause was higher.

Association with Combined Occupational Hazards Exposure and Risk of Metabolic Syndrome: A Workers' Health Examination Cohort 2012-2021

  • Dongmug Kang ;Eun-Soo Lee ;Tae-Kyoung Kim;Yoon-Ji Kim ;Seungho Lee ;Woojoo Lee ;Hyunman Sim ;Se-Yeong Kim
    • Safety and Health at Work
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    • v.14 no.3
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    • pp.279-286
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    • 2023
  • Background: This study aimed to evaluate the association between exposure to occupational hazards and the metabolic syndrome. A secondary objective was to analyze the additive and multiplicative effects of exposure to risk factors. Methods: This retrospective cohort was based on 31,615 health examinees at the Pusan National University Yangsan Hospital in Republic of Korea from 2012-2021. Demographic and behavior-related risk factors were treated as confounding factors, whereas three physical factors, 19 organic solvents and aerosols, and 13 metals and dust were considered occupational risk factors. Time-dependent Cox regression analysis was used to calculate hazard ratios. Results: The risk of metabolic syndrome was significantly higher in night shift workers (hazard ratio = 1.45: 95% confidence interval = 1.36-1.54) and workers who were exposed to noise (1.15:1.07-1.24). Exposure to some other risk factors was also significantly associated with a higher risk of metabolic syndrome. They were dimethylformamide, acetonitrile, trichloroethylene, xylene, styrene, toluene, dichloromethane, copper, antimony, lead, copper, iron, welding fume, and manganese. Among the 28 significant pairs, 19 exhibited both positive additive and multiplicative effects. Conclusions: Exposure to single or combined occupational risk factors may increase the risk of developing metabolic syndrome. Working conditions should be monitored and improved to reduce exposure to occupational hazards and prevent the development of the metabolic syndrome.

Use of Discriminant Analysis to Identify Soil Quality Variation by Land Use (판별분석을 이용한 토지이용별 토양 특성 변화 연구)

  • Ko Kyung-Seok;Kim Jae Gon;Lee Jin-Soo;Kim Tack Hyun;Lee Gyoo Ho;Cho Choon Hee;Oh In Suk;Cheong Young Wook
    • Economic and Environmental Geology
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    • v.38 no.3 s.172
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    • pp.207-219
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    • 2005
  • The physical and chemical characteristics of soils in a small watershed were investigated and the effect of geology and land use on soil quality were examined by using multivariate statistical methods, principal components analysis and discriminant analysis. The soil developed from andesite had finer texture and higher contents of water extractable inorganic components, clay, and mafic minerals than the soil developed from granite. It is considered that the accumulation of salts in the farmland soils indicated by electrical conductivity, contents of cations and anions and pH was caused by fertilizer input during cultivation. The low contents of organic matter in the farmland soils was due to the enhanced oxidation of organic matter by tillage and by the harvest of crops. The contents of inorganic components are increased as following order: upland > orchard > paddy field > forest. The high contents of water soluble $SO_4\;^{2-}$ of paddy soils is due to the oxidation of sulfides mineral formed during the flooding period during the air-dry and extraction. The results of principal components analysis show the difference of soil quality was controlled by geology and land use. PCI indicate the input of fertilizer, mineral weathering and ion exchange reaction by application of nitrogenous fertilizers. The results of two discriminant analyses using water extractable inorganic components and their ratios by land use were also clearly classified by discriminant function 1 and 2. In discriminant analysis by components, discriminant function 1 indicated the effect of fertilizer application and increased as following order: upland > orchard > paddy field > forest soil. The investigated and predicted data for land use from discriminant analysis showed similar results. The discriminant analysis can be used as a useful method certifying the change of land use.

Analysis of Nested Case-Control Study Designs: Revisiting the Inverse Probability Weighting Method

  • Kim, Ryung S.
    • Communications for Statistical Applications and Methods
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    • v.20 no.6
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    • pp.455-466
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    • 2013
  • In nested case-control studies, the most common way to make inference under a proportional hazards model is the conditional logistic approach of Thomas (1977). Inclusion probability methods are more efficient than the conditional logistic approach of Thomas; however, the epidemiology research community has not accepted the methods as a replacement of the Thomas' method. This paper promotes the inverse probability weighting method originally proposed by Samuelsen (1997) in combination with an approximate jackknife standard error that can be easily computed using existing software. Simulation studies demonstrate that this approach yields valid type 1 errors and greater powers than the conditional logistic approach in nested case-control designs across various sample sizes and magnitudes of the hazard ratios. A generalization of the method is also made to incorporate additional matching and the stratified Cox model. The proposed method is illustrated with data from a cohort of children with Wilm's tumor to study the association between histological signatures and relapses.