• Proceedings of the Korea Water Resources Association Conference
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• 2012.05a
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• pp.79-82
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• 2012

최근 지진해일 발생으로 인한 막대한 피해로 인해 지진해일 방재에 대한 중요성이 높아지고 있다. 지진해일 방재연구는 주로 실제 발생하였던 역사지진해일과 발생가능성이 높은 가상의 지진해일에 대해 해당지역의 재해정보도를 제작하여, 지진해일 발생 시 인명 및 재산피해를 최소화 하는 것에 초점이 맞추어져 있다. 따라서 이번 연구에서는 이러한 재해정보도의 효율성을 높이기 위해 지진해일 발생 시 인명피해가 발생할 가능성이 높은 위험지역을 선정하였다. 지진해일 위험지역을 선정하기 위해 가상의 지진해일을 수치모의 하였으며, 지진해일 발생 시 인명피해가 발생할 수 있는 지진해일 범람 높이를 선정하여 선정한 기준 높이 이상의 범람이 발생할 확률을 계산하였다. 지진해일 수치모의는 지진해일 전파모의와 범람모의 과정으로 이루어진다. 지진해일 전파모형은 선형 Boussinesq 방정식을 지배방정식으로 사용하며, 지진해일 범람모형은 비선형 천수방정식을 지배방정식으로 사용하였다. 수치모의를 통해 주문진항에서의 가상의 지진해일에 대한 범람영역 및 범람 높이를 얻었다. 수치모의를 통해 얻어진 범람 데이터를 이용해 기준 높이 이상의 범람 발생 확률을 계산하였다. 확률 계산을 위해선 해당 데이터의 확률분포를 결정하여야 하기 때문에, 적합도 검정을 수행하였다. 이번 연구에서는 여러 가지 적합도 검정 기법 중 하나인 확률도시 상관계수 검정(Probability Plot Correlation Coefficient Test)을 사용하였으며, 범람 데이터의 확률분포로 Normal, Log-normal, Exponential, Gumbel 분포를 가정하여 검정을 수행하였다. 각 지점별로 확률도시 상관계수 검정을 수행하여, 해당 지점의 확률분포를 결정하였고, 각 지점별로 해당하는 확률분포의 누적확률분포 함수를 이용해 기준 높이 이상의 범람이 발생할 확률을 계산하였다. 얻어진 확률을 지도상에 도시하여 기준 높이 이상의 범람 발생 확률이 높은 지점을 주문진항에서의 지진해일에 대한 인명피해 발생 가능성이 높은 위험지역으로 선정하였다.

• Journal of the Earthquake Engineering Society of Korea
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• v.23 no.2
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• pp.101-108
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• 2019

The seismic safety of nuclear power plants has always been emphasized by the effects of accidents. In general, the seismic safety evaluation of nuclear power plants carries out a seismic probabilistic safety assessment. The current probabilistic safety assessment assumes that damage to the structure, system, and components (SSCs) occurs independently to each other or perfect dependently to each other. In case of earthquake events, the failure event occurs with the correlation due to the correlation between the seismic response of the SSCs and the seismic performance of the SSCs. In this study, the EEMS (External Event Mensuration System) code is developed which can perform the seismic probabilistic safety assessment considering correlation. The developed code is verified by comparing with the multiplier n, which is for calculating the joint probability of failure, which is proposed by Mankamo. It is analyzed the changes in seismic fragility curves and seismic risks with correlation. As a result, it was confirmed that the seismic fragility curves and seismic risk change according to the failure correlation coefficient. This means that it is important to select an appropriate failure correlation coefficient in order to perform a seismic probabilistic safety assessment. And also, it was confirmed that carrying out the seismic probabilistic safety assessment in consideration of the seismic correlation provides more realistic results, rather than providing conservative or non-conservative results comparing with that damage to the SSCs occurs independently.

• Korean Journal of Labor Studies
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• v.23 no.1
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• pp.197-220
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• 2017

This paper provides empirical evidence on the impact of increasing import penetration on the job stability of Korean workers. The main results are as follows. First, import penetration negatively affects job stability. If an industry's ratio of imports to total supply increases by 1 percentage point, the turnover probability of workers in that industry increases by 4.5 percentage points. Second, the effect of trade liberalization is not symmetric between imports and exports. Unlike the case of imports, an industry's ratio of exports to output does not have a significant effect on job stability. Third, the impact of import penetration is not uniform across different types of workers. The negative impact is greater for workers in small firms, less educated workers, and those not protected by labor unions.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.2
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• pp.459-467
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• 2021

This study examined the onset of adolescent delinquency through discrete-time survival analysis. Our analysis used data obtained from the Korean Children & Youth Panel Survey, and included 2,277 middle school students. The main analysis results are as follows. First, the hazard probability for the occurrence of delinquency was the highest at 16.6% in the second year of middle school, slightly decreased in the third year of middle school, but continued to increase as the overall grade increased. Second, adolescent psychological and emotional factors have significantly affected the onset of delinquency. Third, negative parenting methods had a significant impact on delinquency, but neglect was not significant. Fourth, having delinquent friends was an important factor affecting the status of delinquency. Fifth, among the school factors, adjustment of learning activities, adjustment of school rules, and adjustment of friendship relations influenced the status of delinquency, while the adjustment of teacher relations was not significant. As early intervention is important to prevent juvenile delinquency, education and support for establishing healthy relationships are needed.

• Journal of Gastric Cancer
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• v.21 no.4
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• pp.335-351
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• 2021

Purpose: An underlying factor for the failure of several clinical trials of anti-epidermal growth factor receptor (EGFR) therapies is the lack of an effective method to identify patients who overexpress EGFR protein. The quantitative dot blot method (QDB) was used to measure EGFR protein levels objectively, absolutely, and quantitatively. Its feasibility was evaluated for the prognosis of overall survival (OS) of patients with gastric cancer. Materials and Methods: Slices of 2×5 ㎛ from formalin-fixed paraffin-embedded gastric cancer specimens were used to extract total tissue lysates for QDB measurement. Absolutely quantitated EGFR protein levels were used for the Kaplan-Meier OS analysis. Results: EGFR protein levels ranged from 0 to 772.6 pmol/g (n=246) for all gastric cancer patients. A poor correlation was observed between quantitated EGFR levels and immunohistochemistry scores with ρ=0.024 and P=0.717 in Spearman's correlation analysis. EGFR was identified as an independent negative prognostic biomarker for gastric cancer patients only through absolute quantitation, with a hazard ratio of 1.92 (95% confidence interval, 1.05-3.53; P=0.034) in multivariate Cox regression OS analysis. A cutoff of 208 pmol/g was proposed to stratify patients with a 3-year survival probability of 44% for patients with EGFR levels above the cutoff versus 68% for those below the cutoff based on Kaplan-Meier OS analysis (log rank test, P=0.002). Conclusions: A QDB-based assay was developed for gastric cancer specimens to measure EGFR protein levels absolutely, quantitatively, and objectively. This assay should facilitate clinical trials aimed at evaluation of anti-EGFR therapies retrospectively and prospectively for gastric cancer.

• Animal Bioscience
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• v.36 no.4
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• pp.591-600
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• 2023

Objective: We aimed to evaluate the efficacy of a modified Double-Ovsynch protocol vs artificial insemination following estrus detection (AIED) for the enhancement of reproductive performance in Hanwoo cattle. Methods: Four hundred twelve Hanwoo cows were allocated to two treatment groups. The first group of cows were administered gonadotropin releasing hormone (GnRH) on Day 36 (±0.6), prostaglandin F_2α (PGF_2α) on Day 46 (8 to 12 days later), and GnRH on Day 49, which was followed by Ovsynch, consisting of an injection of GnRH on Day 56, PGF_2α on Day 63, and GnRH 56 h and timed AI (TAI) 16 h later (modified Double-Ovsynch group, n = 203). The second group of cows underwent AIED (AIED group, n = 209) and were designated as controls. Results: The pregnancy per AI 60 days after the first AI was higher in the modified Double-Ovsynch (68.5%) than in the AIED (56.5%) group, resulting in a higher probability of pregnancy per AI (odds ratio: 1.68, p<0.05). Moreover, cows in the modified Double-Ovsynch group were more likely (hazard ratio: 1.28, p<0.05) to be pregnant by 150 days after calving than cows in the AIED group, and this difference was associated with a lower mean number of AIs per conception (1.27 vs 1.39, p<0.05) and a shorter median interval between calving and pregnancy (72 vs 78 days, p<0.1). Conclusion: The modified Double-Ovsynch protocol, adjusted according to the herd visit schedule, can be readily used to increase the pregnancy per AI following the first AI and to shorten the interval between calving and pregnancy in beef herds.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.5C
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• pp.313-322
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• 2006

Liquefaction of soil foundation is one of the major seismic damage types for infrastructures. In this paper, deterministic and probabilistic approaches for the evaluation of liquefaction potential are briefly summarized and the risk assessment method is newly proposed using seismic fragility and seismic hazard analyses. Currently the deterministic approach is widely used to evaluate the liquefaction potential in Korea. However, it is very difficult to handle a certain degree of uncertainties in the soil properties such as elastic modulus and resistant capacity by deterministic approach, and the probabilistic approaches are known as more promising. Two types of probabilistic approaches are introduced including (1) the reliability analysis (to obtain probability of failure) for a given design earthquake and (2) the seismic risk analysis of liquefaction for a specific soil for a given service life. The results from different methods show a similar trend, and the liquefaction potential can be more quantitatively evaluated using the new risk analysis method.

• Wind and Structures
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• v.37 no.6
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• pp.413-423
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• 2023

Wind turbines are usually steel hollow structures that can be vulnerable to dramatic failures due to high-intensity wind (HIW) events, which are classified as a category of localized windstorms that includes tornadoes and downbursts. Analyzing Wind Turbines (WT) under tornadoes is a challenging-to-achieve task because tornadoes are much more complicated wind fields compared with the synoptic boundary layer wind fields, considering that the tornado's 3-D velocity components vary largely in space. As a result, the supporting tower of the wind turbine and the blades will experience different velocities depending on the location of the event. Wind farms also extend over a large area so that the probability of a localized windstorm event impacting one or more towers is relatively high. Therefore, the built-in-house numerical code "HIW-WT" has been developed to predict the straining actions on the blades considering the variability of the tornado's location and the blades' pitch angle. The developed HIWWT numerical model incorporates different wind fields that were generated from developed CFD models. The developed numerical model was applied on an actual wind turbine under three different tornadoes that have different tornadic structure. It is found that F2 tornado wind fields present significant hazard for the wind turbine blades and have to be taken into account if the hazardous impact of this type of unexpected load is to be avoided.

• Annals of Hepato-Biliary-Pancreatic Surgery
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• v.27 no.3
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• pp.251-257
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• 2023

Backgrounds/Aims: This is a retrospective analysis of whether the 8th edition American Joint Committee on Cancer (AJCC) was a significant improvement over the 7th AJCC distal extrahepatic cholangiocarcinoma classification. Methods: In total, 111 patients who underwent curative resection of mid-distal bile duct cancer from 2002 to 2019 were included. Cases were re-classified into 7th and 8th AJCC as well as clinicopathological univariate and multivariate, and Kaplan-Meier survival curve and log rank were calculated using R software. Results: In patient characteristics, pancreaticoduodenectomy/pylorus preserving pancreaticoduodenectomy had better survival than segmental resection. Only lymphovascular invasion was found to be significant (hazard ratio 2.01, p = 0.039) among all clinicopathological variables. The 8th edition AJCC Kaplan Meier survival curve showed an inability to properly segregate stage I and IIA, while there was a large difference in survival probability between IIA and IIB. Conclusions: The 8th distal AJCC classification did resolve the anatomical issue with the T stage, as T1 and T3 showed improvement over the 7th AJCC, and the N stage division of the N1 and N2 category was found to be justified, with poorer survival in N2 than N1. Meanwhile, in TMN staging, the 8th AJCC was able differentiate between early stage (I and IIA) and late stage (IIB and III) to better explain the patient prognosis.

• Journal of Veterinary Clinics
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• v.30 no.3
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• pp.178-185
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• 2013

This study evaluated the effects of milk yield on the postpartum health and reproductive performance of dairy cows. In total, data were collected from 1,060 cows on six dairy farms, including their milk production, body condition score (BCS), postpartum disorders, and reproductive performance. The lactation data were grouped based on the 305-day milk yield into control (< 10,000 kg, n = 445) and high milk yield (${\geq}$ 10,000 kg, n = 615) groups. The milk fat and protein, and BCS were lower during the first 5 months postpartum in the high milk yield group compared with the control group (p < 0.01). Ovarian cysts were more frequent (p < 0.0001) in the high milk yield group (28.6%) than in the control group (15.3%), whereas endometritis tended to be less frequent in the high milk yield group (29.6%) than in the control group (35.1%, p = 0.06). A higher proportion of cows tended to receive reproductive hormones (p = 0.06) in the high milk yield group (62.4%) than in the control group (56.6%). The probability of a pregnancy after first insemination tended to be lower (odds ratio = 0.78, p = 0.07) in the high milk yield group (30.2%) than in the control group (35.2%). Furthermore, the hazard of pregnancy by 210 days in milk was lower in the high milk yield group (hazard ratio = 0.84, p = 0.04) than in the control group, which resulted in a 20-day increase in the median interval to pregnancy. In conclusion, high milk yield was related to lower milk fat and protein, lower BCS, an increased incidence of ovarian cysts, and increased use of reproductive hormones, which resulted in decreased reproductive performance of dairy cows.