• Journal of Korean Society of Industrial and Systems Engineering
• /
• v.40 no.2
• /
• pp.31-40
• /
• 2017

In this paper, we compared the efficiencies of national R&D investments between NT (Nanotechnology) areas in terms of papers, patents, and commercializations, and found ways to improve the efficiencies of national R&D investments for each NT area. This is in response to huge R&D investments government has made recently in NT areas. Here, we collected data on investments, papers, patents, and commercializations for the R&D projects in NT areas through National Science & Technology Information Service. Based on the data, we analyzed the investment and performances (papers, patents, and commercializations) for each NT area, calculated the efficiency for each NT area, and compared the efficiencies between NT areas. Next, using cluster analysis, we identified several NT areas with similar characteristics in terms of paper efficiency, patent efficiency and commercialization efficiency. Finally, we derived implications for the efficiency enhancement for each grouping. The cluster analysis showed that there could be two groups, one being low in terms of technological outcome (papers and patents) efficiencies and high in terms of commercialization efficiencies, while the other being high in terms of technological outcome (papers and patents) efficiencies and low in terms of commercialization efficiencies. Therefore, the strategy for one group calls for support for technology transfer or technology introduction from other R&D performers and grant of guidance for improving R&D performers' commercialization ability to other R&D performers while the strategy for the other group calls for R&D support for transfer of technology to other R&D performers, activation of technology transfer and support for commercialization of R&D performers.

• Journal of the Society of Cosmetic Scientists of Korea
• /
• v.31 no.3 s.52
• /
• pp.245-251
• /
• 2005

Safety is one of the key issue in the regulation of cosmetics. Cosmetic Act deals with it in Korea. The guidance for the testing cosmetic ingredients and their safety evaluation are prepared by Korea Food and Drug Administration. Ultraviolet radiation could Induce skin damage, edema, erythema, photoaging, immune dysfunction and skin cancer. Ultraviolet radiation is classified as Group 2A(probably carcinogenic to humans) by International Agenry for Reaserch on Cancer(IARC). The in vitro methodologies for evaluating the toxic potential of ingredients reported in the literature have not yet been sufficiently validated for use in areas other than the study for mutagenicity/genotoxicity, for pre-screening for severe irritancy, for screening of phototoxicity and for evaluating the percutaneous absorption. The 3T3 neutral red uptake photoxicity test (3T3 NRU PT) was accepted as OECD toxicity guideline in 2002. The 3T3 NRU PT is an in vitro method based on a comparison of the cytotoxicitv of a chemical when tested in the presence and in the absence of exposure to a non-cytotoxic dose of UVA/visible light.

• Journal of dental hygiene science
• /
• v.9 no.2
• /
• pp.241-247
• /
• 2009

The objective of this research can be found in its use as a basic material to induce students from the department of dental hygiene to quit smoking, by raising the awareness of tobacco cessation as well as the actual smoking state. The graduating undergraduates from 10 universities (including colleges) based on their 61 major departments across the country took pan in this questionnaire. The questionnaire basically consists of the understanding of smoking, a state of smoking or tobacco cessation(5 questions), and the advisory guidance on quit smoking(4 questions). The questionnaire on the awareness of smoking relating to those work for the health and medical services is based upon the papers published from WHO (World Health Organization), which is aimed to find out the smoking rate of those involved in the health and medical services around the world. In addition, an adequate education for smoking students from the department of dental and hygiene should be taken into account in an effort to raise the awareness of smoking and the necessity of tobacco cessation.

• Journal of the Korean Dietetic Association
• /
• v.12 no.1
• /
• pp.55-67
• /
• 2006

The purpose of this study was to compare the food behavior and nutrient intakes, and the analysis of constituent parts of blood related to iron nutrition conditions and to investigate the correlation between iron nutrition conditions and obesity. Each subject was assigned to one of such as normal(n=55) and obese groups(n=60) according to their obesity index. Their nutritional status, serum iron status were evaluated based in 24-hr dietary recalls, questionnaire and blood analysis. The mean age of the normal group(10.76 years) and that of the obese group(10.95 years) made little difference. The height(p<0.05), weight(p<0.001), and obesity index(p<0.001) in the obese group were higher than those of the normal group in every respect. The 63.55% of the subject of this study gave an answer 'They eat breakfast daily', and the frequency of eating breakfast made little difference. The average intakes of energy were 1669.44 kcal(84.19% of EER) in the obese group and 1673.59 kcal(86.72% of EER) in the normal group respectively, which made little difference between two groups. The intake of nutrients such as calcium and folate was as insufficient as below 75% of RI. The heme iron intake of the obese group was low that of the normal group(p<0.05). Among the major 20 iron resources the iron intake through animal food intake were 1.43 mg(12.00%) in the obese group and 1.93 mg(17.72%) in the normal group respectively. The rating of iron condition in the blood showed that the number of red blood cell(p<0.01), the hemoglobin(p<0.001), and hematocrit(p<0.01) of the obese group were lower than those of the normal group. These results suggest that there should be the right choice of food according to its bioavailability and nutritive guidance to appropriate food behavior, in addition to increasing iron intake to improve iron nutrition conditions of obese male elementary school students.

• Journal of the Korean Dietetic Association
• /
• v.12 no.2
• /
• pp.172-184
• /
• 2006

This study was aimed to provide safety management guidance by evaluating the microbial quality of cooked dried-seafoods in school foodservice operations. Nineteen seafood items were collected from six elementary schools, those were dried-anchovy, dried-seaweed and dried-fish, which were classified as cooking process. The temperatures at receiving and after cooking were measured and the analyses of cooking processes and microbial quality were performed. The temperatures of all foods after cooking were higher than the temperature limit of $74\^circC$. The number of total aerobic bacteria and S. aureus in dried-anchovy over the limit of $10^5$ and even the level of S. aureus was found to be unsatisfactory. The count of total aerobic bacteria was 2.1x$10^8$ CFU/g and the number of total aerobic bacteria after cooking was over the limit in one school. The level of E. coli (3.1x$10^3$ CFU/g) was over the limit at one school and the number of S. aureus (1.2×$10^4$ CFU/g) was considered as unacceptable. Dried- tangle and green laver were contaminated with total aerobic bacteria showing the over the limit. The numbers of total aerobic bacteria in dried- filefish, pollack and squid were 4.3x$10^6$, 3.4x$10^6$-3.9x$10^7$ and 4.6x$10^5$-4.1x$10^7$ CFU/g, respectively, which were in acceptable or unsatisfactory level. The E. coli in dried- filefish and pollack were over the limit. The total aerobic bacteria levels, 4.6x$10^5$-1.5x$10^6$ CFU/g in dried-pollack and 8.0x$10^5$-2.2x$10^7$ CFU/g in dried-squid, were over the limit after cooking except dried-filefish. The E. coli levels, 4.3x$10^3$ CFU/g in dried-filefish and 2.5x$10^2$ CFU/g in dried-pollack, were over the limit of $10^2$ CFU/g. The numbers of Enterobacteriaceae were either acceptable (3.3x$10^3$ CFU/g) or unsatisfactory (1.6x$10^4$ CFU/g) level in dried-pollack. S. aureus was unsatisfactory level (6.5x$10^4$ CFU/g) in dried-filefish while unacceptable in dried-pollack both before and after cooking. Unacceptable levels of S. aureus, 2.4x$10^4$ and 1.3x$10^5$ CFU/g were found from two schools, respectively. These results suggest that the contamination of raw materials and the seasonings added after cooking should be controlled to manage the microbial safety of cooked dried-seafoods.

• Journal of Digital Convergence
• /
• v.14 no.11
• /
• pp.441-448
• /
• 2016

The purpose of this study was to identify the effects of mentoring senior core fundamental nursing skills education on clinical competence and critical thinking disposition in nursing students. The research design was a one group pre-posttest design and the participants were 57 nursing students. The contents consisted of 3 core fundamental nursing skills of vital sign, nelaton catheterization and subcutaneous injection and total duration of 6 hours. Mentoring seniors conducted to rapport forming & education and evaluated them after exercise and evaluation under the guidance of professor. Data were collected using self-administered questionnaires in pre-test and post-test, the collected data were analyzed using paired t-tests. The result shows the scores of clinical competence and critical thinking disposition were increased significantly after mentoring senior core fundamental nursing skills education in nursing students. The results indicate that this study was effective in improving nursing students clinical competence and critical thinking disposition in core fundamental nursing skills and is expected to be utilized in nusing practice education. Additional studies including those on control groups are recommended to compare difference between the experimental group and control group.

• Korean Journal of Environment and Ecology
• /
• v.24 no.2
• /
• pp.101-107
• /
• 2010

This study was carried out to provide basic data for efficient park management by analysing visitors' satisfaction factors and estimated regression model through questionnaire survey method at Taeanhaean National Park in Korea. Performance(satisfaction) variables as 'touting', 'illegal merchant', 'noise', 'indiscreet use' and 'collection of natural plants or animals', and Importance variables as 'littering problem', 'water pollution act', 'careless cooking' and 'exorbitant pay' were relatively high score. It was clarified that the 'souvenir & special product', 'lack of use program' 'lack of public facility', 'lack of information facility', and 'lack of commercial facility' were 'concentrate here' ones by the Importance-Performance analysis. 'Facility management', 'Use management' and 'Resource management' factors were found out by Factor Analysis and the 'Facility management' was the biggest factor accounting for 32.6% of all. In the estimated model by Multiple Regression Analysis, 'lack of employee's guidance or kindness', 'lack of convenience facility', 'noise', 'lack of facilities to stay' and 'charge of user fee, parking fee' were the variables to impact visitors' satisfaction and to need concentrated management. These results were unique characteristics of marine national park and then the different management strategy and policy from mountain national park were necessary.

• Korean Journal of Environment and Ecology
• /
• v.23 no.1
• /
• pp.78-89
• /
• 2009

As 'design for all' and 'adaptable design', universal design is highly demanded to be adopted in neighborhood forest trail. The research areas were Mt. Doeum in Pohang, Gyeongsangbuk Province and Mt. Anma in Chuncheon, Gangwon Province which were equipped based on 7 principles of universal design. The purpose of this research is providing baseline data for effective formulation of forest trail using universal design through visitors' evaluation on forest trail facilities by importance-performance analysis. Visitor's evaluation was achieved through questionnaire survey, and total 247 pieces of subjects were used for the analysis, 114 pieces from Mt. Doeum in Pohang and 113 pieces from Mt. Anma in Chuncheon. The residential areas of the respondents were mainly near each mountain - Mt. Doeum and Mt. Anma. According to the responses, nature study and education were the biggest reasons for the respondents' visits to Mt. Doeum, and so was the health to Mt. Anma, which are representative types of visiting behavior to nearby forest trails. The mean of importance was shown to be 3.87 while that of performance was 4.04, being a little higher than importance's, in importance-performance analysis of Mt. Doeum. This result suggests that the responders placed positive value on the forest trail applying universal design. It is necessary to improve the safety and convenience of guidance-safety handrail, make information sign easy to understand, and introduce an interpretive sign meeting the visiting purposes of visitors. Also, the management to make the road surface flat is in demand for the accessibility to forest trail. The mean of importance was 3.92 and that of performance was 3.99 in Mt. Anma, which suggests the necessity of improvement in safety of pavement material and boundary safety facilities.

• Clean Technology
• /
• v.17 no.4
• /
• pp.285-299
• /
• 2011

As one of the REACH obligations, the extended safety data sheet (eSDS) should be communicated within the supply chain under the REACH Regulation. Based on technical guidance documents published on the ECHAs website and survey of EU's recent REACH-related informations, this paper includes a study on details of how to develop exposure scenarios (ES) such as structure of ES, process of ES develpoment, standard workflows and key input data to develop ES with an introduction of eSDS concept. This paper also contains an overview on operational conditions (OCs) and risk management measures (RMMs) that are what to consider when building an ES. The structure of Chesar (Chemical Safety Assessment and Report tool) developed by European Chemicals Agency (ECHA) is studied with a review of the available exposure estimation tools for workers, environment and consumers. Case example of generic exposure scenario (GES) for organic solvent is presented. To guide Korean EU-exporting companies, their participating roles in three steps of preparing ES are addressed.

• Journal of Ginseng Research
• /
• v.41 no.2
• /
• pp.209-214
• /
• 2017

Background: Both ginsenoside Re and B-complex vitamins are widely used as nutritional supplements. They are often taken together so as to fully utilize their antifatigue and refreshing effects, respectively. Whether actually a drug-nutrient interaction exists between ginsenoside Re and B-complex vitamins is still unknown. The objective of this study was to simultaneously investigate the effect of B-complex vitamins on the antifatigue activity and bioavailability of ginsenoside Re after their oral administration. The study results will provide valuable theoretical guidance for the combined utilization of ginseng and B-complex vitamins. Methods: Ginsenoside Re with or without B-complex vitamins was orally administered to mice to evaluate its antifatigue effects and to rats to evaluate its bioavailability. The antifatigue activity was evaluated by the weight-loaded swimming test and biochemical parameters, including hepatic glycogen, plasma urea nitrogen, and blood lactic acid. The concentration of ginsenoside Re in plasma was determined by liquid chromatography-tandem mass spectrometry. Results: No antifatigue effect of ginsenoside Re was noted when ginsenoside Re in combination with B-complex vitamins was orally administered to mice. B-complex vitamins caused to a reduction in the bioavailability of ginsenoside Re with the area under the concentration-time curve from zero to infinity markedly decreasing from $11,830.85{\pm}2,366.47h{\cdot}ng/mL$ to $890.55{\pm}372.94h{\cdot}ng/mL$. Conclusion: The results suggested that there were pharmacokinetic and pharmacodynamic drug-nutrient interactions between ginsenoside Re and B-complex vitamins. B-complex vitamins can significantly weaken the antifatigue effect and decrease the bioavailability of ginsenoside Re when simultaneously administered orally.